CN101983683A - Traditional Chinese medicine for treating diabetic pruritus - Google Patents

Abstract

The invention relates to a traditional Chinese medicine with the characteristics of good and fast effect on treating diabetic pruritus, which belongs to the field of traditional Chinese medicine for treating diabetes. The tranditional Chinese medicine is prepared by using anemarrhena, mulberry, ganoderma, pseudo-ginseng, Chinese angelica, catnip and sophora flavescens as raw materials. The above medicine, which has a fast, certain and obvious effect on treating diabetic pruritus, has the advantages of reinforcing the vital energy, consolidating the constitution, replenishing qi and blood, activating blood, dissolving stasis, dissipating heat, drying the damp and expelling wind to arrest itching.

Description

A traditional Chinese medicine for treating diabetic skin itching

technical field

The invention belongs to the field of traditional Chinese medicine for treating diabetes.

Background technique

Diabetic skin itching is one of the common complications of diabetes, and about 1/5 of diabetics suffer from it. This itching is generalized and very persistent. The current traditional Chinese medicine aimed at treating diabetic skin itching has two deficiencies: one is that the effect is not obvious enough; The itching is unbearable, scratching all night, and it is difficult to fall asleep. The patient and his family are very dissatisfied with this.

Aiming at the problems raised above, the present invention provides a traditional Chinese medicine for treating diabetic skin itching, which can solve the problem that the effect of traditional Chinese medicines in the past is not obvious enough, and the effect is relatively slow. Exactly, the advantage of quicker effect.

Contents of the invention

The present invention is achieved through the following technical solutions:

1, a kind of Chinese medicine for the treatment of diabetic skin pruritus, adopts Chinese medicine raw material to prepare, and formula is (by weight):

Anemarrhena 5-15 parts Mulberry 6-18 parts Ganoderma lucidum 6-18 parts

Panax notoginseng 3-9 parts Angelica 6-18 parts Nepeta 5-15 parts

Sophora flavescens 5-15 parts

This traditional Chinese medicine for diabetic skin itching is made by the following methods:

(1) According to the above weight ratio, extract Ganoderma lucidum polysaccharides from Ganoderma lucidum with water extraction and alcohol precipitation method, the process is as follows: crush Ganoderma lucidum into granules, pass through a 40-mesh sieve → leaching with 1:20 hot water (95°C) → leaching Extract the liquid under reduced pressure, concentrate → mix with 3 times the volume of 95% ethanol, let stand for 10-12 hours, centrifuge → add 75% ethanol, precipitate polysaccharide → dry to obtain fine powder of Ganoderma lucidum polysaccharide extract;

(2) according to the above-mentioned weight ratio, anemarrhena, mulberry fruit, angelica, nepeta, and flavescens are extracted through a conventional water extraction process to make extract extract fine powder;

(3) According to the above weight ratio, grind Radix Notoginseng into a fine powder, mix with the fine powder of the above two kinds of extracts (1) and (2), stir evenly, and make traditional Chinese medicine granules, capsules, and tablets.

The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. Our research suggests that the pathogenesis of diabetic pruritus is skin microvascular lesions and tissue ischemia. Diabetic patients have low immunity, endogenous dryness, thick blood, poor blood flow, microcirculation disorder in the skin, insufficient blood supply, and itching. In this prescription, Ganoderma lucidum and mulberry strengthen the body, nourish qi and blood, nourish the heart and calm the nerves, and enhance the body's immunity; Blood foot, the "clearing" and "repairing" effect of immunity promotes blood cleansing, no longer sticky, microcirculation is improved, and blood supply is filled. Supplemented with Sophora flavescens to clear away heat and dampness, it is good at treating stubborn tinea and pruritus vulvae. All the medicines are compatible and complement each other. They play the role of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing away heat and dampness, expelling wind and relieving itching, with good effect and quick effect. advantage.

Detailed ways

The present invention is specifically described by the following embodiments:

1. Take the following formula (weight is in grams):

Anemarrhena 50g Mulberry 60g Ganoderma lucidum 60g

Panax notoginseng 30 grams Angelica sinensis 60 grams Nepeta 50 grams

Sophora flavescens 50 grams

Extract Ganoderma lucidum by water extraction and alcohol precipitation method according to the specified weight; extract Anemarrhena, Mulberry, Angelica, Schizonepeta, and Sophora flavescens with conventional water extraction technology, and make a total of 66 grams of fine powder of the extract, and grind Panax notoginseng into fine powder Powder, mixed with the above-mentioned extract fine powder, stirred evenly, made into fine particles, packed into No. 0 capsules, and made into 342 Chinese medicine capsules, each capsule containing Chinese medicine fine powder and 0.28 grams of extract.

2. Take the following formula (weight is in grams):

Anemarrhena 100g Mulberry 120g Ganoderma lucidum 120g

Panax notoginseng 60 grams Angelica 120 grams Nepeta 100 grams

Sophora flavescens 100 grams

By above-mentioned same method, make 685 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.

3. Take the following formula (the weight is in grams):

Anemarrhena 150g Mulberry 180g Ganoderma lucidum 180g

Panax notoginseng 90 grams Angelica 180 grams Nepeta 150 grams

Sophora flavescens 150g

By the above-mentioned same method, 1028 Chinese medicine capsules were made, and each capsule contained Chinese medicine fine powder and 0.28 grams of extract.

4. Take the following formula (by weight):

Anemarrhena 8 parts Mulberry 9 parts Ganoderma lucidum 9 parts

Panax notoginseng 4 parts Angelica 9 parts Nepeta 8 parts

Sophora 8 servings

By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

5. Take the following formula (by weight):

Anemarrhena 12 parts Mulberry 16 parts Ganoderma lucidum 16 parts

Panax notoginseng 7 parts Angelica 16 parts Nepeta 12 parts

Sophora flavescens 12 parts

By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

clinical information:

The present invention takes diabetic pruritus as an example, through clinical observation of 6 cases. TCM diabetic skin itching was selected as the standard: Diabetic patients have serious wasting, limb weakness, skin itching, long-term treatment, affecting sleep. The above symptoms can be diagnosed. Among the objects confirmed and observed, there were 4 males and 2 females, without other serious diseases, aged from 44 to 81 years old, with an average age of 63.8 years.

Judgment of curative effect:

1. Significant effect: Physical fitness is enhanced, limbs are strong; itching is significantly relieved, and sleep is improved.

2. Effective: the body is strengthened, and the degree of itching is relieved.

3. Ineffective: no change in symptoms.

During clinical trials, except for the necessary hypoglycemic drugs for diabetic patients, stop taking other drugs and health nutrition products. Take Chinese medicine capsule of the present invention, observe 2 months and be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.28g of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 2 months of taking, Symptoms improved significantly. In the 6 clinical trials, 3 people were markedly effective, 2 people were effective, and 1 person was ineffective, and the total effective rate was 83.3%.

Claims (1)

1. Chinese medicine for the treatment of diabetic skin pruritus, it is characterized in that: it is to make with the component of following weight ratio: Rhizoma Anemarrhenae 5-15 part, Fructus Mori 6-18 part, Ganoderma 6-18 part, Radix Notoginseng 3-9 part, Radix Angelicae Sinensis 6-18 part, Herba Schizonepetae 5-15 part, Radix Sophorae Flavescentis 5-15 part.