CN102091218A - Traditional Chinese medicine for treating diabetic skin pruritus - Google Patents
Traditional Chinese medicine for treating diabetic skin pruritus Download PDFInfo
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- CN102091218A CN102091218A CN2010105659746A CN201010565974A CN102091218A CN 102091218 A CN102091218 A CN 102091218A CN 2010105659746 A CN2010105659746 A CN 2010105659746A CN 201010565974 A CN201010565974 A CN 201010565974A CN 102091218 A CN102091218 A CN 102091218A
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- CN
- China
- Prior art keywords
- chinese medicine
- traditional chinese
- radix
- skin pruritus
- diabetic skin
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- 208000003251 Pruritus Diseases 0.000 title claims abstract description 23
- 239000003814 drug Substances 0.000 title claims abstract description 23
- 206010012601 Diabetes mellitus Diseases 0.000 title claims abstract description 19
- 210000003491 Skin Anatomy 0.000 title claims abstract description 16
- 241000222336 Ganoderma Species 0.000 claims abstract description 10
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 11
- 241000180649 Panax notoginseng Species 0.000 claims description 11
- 230000000694 effects Effects 0.000 abstract description 13
- 210000004369 Blood Anatomy 0.000 abstract description 10
- 239000008280 blood Substances 0.000 abstract description 10
- 230000017531 blood circulation Effects 0.000 abstract description 5
- 229940079593 drugs Drugs 0.000 abstract description 4
- 230000001737 promoting Effects 0.000 abstract description 4
- 230000000857 drug effect Effects 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 abstract description 2
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 240000005111 Asparagus cochinchinensis Species 0.000 abstract 1
- 235000009292 Asparagus cochinchinensis Nutrition 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 240000004678 Panax pseudoginseng Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 241000951473 Schizonepeta Species 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 239000002775 capsule Substances 0.000 description 15
- 239000000843 powder Substances 0.000 description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 201000010099 disease Diseases 0.000 description 4
- AXONCVPTTFHNOI-UHFFFAOYSA-N Kairine Chemical compound C1=CC(O)=C2N(C)CCCC2=C1 AXONCVPTTFHNOI-UHFFFAOYSA-N 0.000 description 3
- 241000207961 Sesamum Species 0.000 description 3
- 235000003434 Sesamum indicum Nutrition 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 210000003414 Extremities Anatomy 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- 238000007560 sedimentation technique Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000003809 water extraction Methods 0.000 description 2
- 206010061255 Ischaemia Diseases 0.000 description 1
- 206010062198 Microangiopathy Diseases 0.000 description 1
- 239000003472 antidiabetic agent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 201000004624 dermatitis Diseases 0.000 description 1
- 231100000406 dermatitis Toxicity 0.000 description 1
- 230000002708 enhancing Effects 0.000 description 1
- 230000003203 everyday Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 150000004676 glycans Polymers 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 201000002367 primary immunodeficiency disease Diseases 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 210000001519 tissues Anatomy 0.000 description 1
- 230000002588 toxic Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002936 tranquilizing Effects 0.000 description 1
Abstract
The invention relates to a traditional Chinese medicine for treating diabetic skin pruritus, belonging to the field of traditional Chinese medicines for treating diabetes. The traditional Chinese medicine is prepared from asparagus cochinchinensis, mulberry fruit, lucid ganoderma, radix pseudo-ginseng, Chinese angelica, fineleaf schizonepeta herb, lightyellow sophora root and other raw materials. The traditional Chinese medicine has the effects of supporting health energy, invigorating qi, nourishing blood, promoting blood circulation, dispersing blood stasis, clearing away heat, eliminating dampness, dispelling wind and arresting itching, and has the advantages of distinct effect, definite drug effect and quick action.
Description
Technical field
The invention belongs to the field of Chinese medicines of treatment diabetes.
Background technology
Diabetic skin pruritus is one of diabetes common complication, has 1/5 diabetes patient to suffer from this disease approximately.This pruritus is a kind of general, and very obstinate.The present Chinese medicine that is intended to treat diabetic skin pruritus, the deficiency that has two aspects: the one, effect is obvious inadequately, the 2nd, it is slower to take effect, owing to can not get the active drug treatment, the patient is standing the torment of pruritus throughout the year---and whole body is very itched unbearable, is difficult to stand, all night scratching, have difficulty in going to sleep, patient and family members thereof are very dissatisfied to this.
At problem set forth above, the invention provides a kind of Chinese medicine for the treatment of diabetic skin pruritus, it is obvious inadequately that it can solve in this type of treatment by Chinese herbs in the past effect, the slower problem that takes effect, effective, instant effect, it is remarkable to have effect, drug effect is definite, the advantage of quick result.
Summary of the invention
The present invention is achieved through the following technical solutions:
1, a kind of Chinese medicine for the treatment of diabetic skin pruritus adopts the raw material of Chinese medicine preparation, and filling a prescription is (by weight):
Radix Asparagi 5-15 part Fructus Mori 6-18 part Ganoderma 6-18 part
Radix Notoginseng 3-9 part Radix Angelicae Sinensis 6-18 part Herba Schizonepetae 5-15 part
Radix Sophorae Flavescentis 5-15 part
The Chinese medicine of this treatment diabetic skin pruritus is made by following method:
(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is as follows: Ganoderma is broken into graininess, cross 40 mesh sieves →, concentrate → mixed, leave standstill 10-12 hour, centrifugal → as to add 75% ethanol with 95% ethanol of 3 times of volumes with 1: 20 hot water (95 ℃) lixiviate → lixiviating solution decompression, precipitate polysaccharide → dry the ganoderan extract fine powder;
(2) by above-mentioned weight ratio, Radix Asparagi, Fructus Mori, Radix Angelicae Sinensis, Herba Schizonepetae, Radix Sophorae Flavescentis are extracted through conventional water extraction process, make extract extractum fine powder;
(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, make Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.
The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think that the pathogenesis of diabetic skin pruritus is the microangiopathies and the tissue local ischemia of skin at research.The diabetics hypoimmunity, production of dryness-heat in the interior, blood is sticky, and blood flow is not smooth, and microcirculation disturbance appears in skin, blood supply insufficiency, pruritus is given birth to therefrom.Ganoderma, Fructus Mori the body resistance strengthening and constitution consolidating among the we, benefiting QI and nourishing blood, tranquilizing by nourishing the heart, enhancing human body immunity power; Radix Angelicae Sinensis, Radix Notoginseng passage, nourishing blood, blood circulation promoting and blood stasis dispelling, Ganoderma, Fructus Mori and Radix Angelicae Sinensis, Radix Notoginseng are associated with, the prosperous hemapodium of gas, " removing " of immunity and " reparation " effect promote blood clean, and no longer sticky, microcirculation improves, and blood supply is full, and this is the key of treatment primary disease; Minister is nourshing Yin and drynsessmoistening prescription with Radix Asparagi, removing heat-phlegm; Be aided with the Radix Sophorae Flavescentis heat clearing and damp drying, kind stubborn dermatitis, the pudendal pruritus controlled; Herba Schizonepetae a surname saturating sending out of loosing, dispelling wind for relieving itching, the two share, and specially controls damp and hot pathogenic wind toxic and attacks in the pruritus of skin unbearably.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, the merit of dispelling wind for relieving itching, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.
The specific embodiment
By following embodiment the present invention is done and to specify:
1, get following prescription (weight is unit by gram):
Radix Asparagi 50 gram Fructus Moris 60 kairine sesames 60 grams
Radix Notoginseng 30 gram Radix Angelicae Sinensis 60 gram Herba Schizonepetae 50 grams
Radix Sophorae Flavescentis 50 grams
Weight is extracted Ganoderma with decoction and alcohol sedimentation technique in accordance with regulations; With conventional water extraction process Radix Asparagi, Fructus Mori, Radix Angelicae Sinensis, Herba Schizonepetae, Radix Sophorae Flavescentis are extracted, make extract fine powder 66 grams altogether, Radix Notoginseng is ground into fine powder, mix with said extracted thing fine powder, stir, make fine particle, the capsule of packing into No. 0, make 342 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
2, get following prescription (weight is unit by gram):
Radix Asparagi 100 gram Fructus Moris 120 kairine sesames 120 grams
Radix Notoginseng 60 gram Radix Angelicae Sinensis 120 gram Herba Schizonepetae 100 grams
Radix Sophorae Flavescentis 100 grams
By above-mentioned same method, make 685 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
3, get following prescription (weight is unit by gram):
Radix Asparagi 150 gram Fructus Moris 180 kairine sesames 180 grams
Radix Notoginseng 90 gram Radix Angelicae Sinensis 180 gram Herba Schizonepetae 150 grams
Radix Sophorae Flavescentis 150 grams
By above-mentioned same method, make 1028 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
4, get following prescription (by weight):
8 parts of 8 portions of Ganodermas of 6 portions of Fructus Moris of Radix Asparagi
6 parts of 8 portions of Herba Schizonepetae of 3 parts of Radix Angelicae Sinensis of Radix Notoginseng
6 parts of Radix Sophorae Flavescentiss
By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
5, get following prescription (by weight):
16 parts of 16 portions of Ganodermas of 12 portions of Fructus Moris of Radix Asparagi
12 parts of 16 portions of Herba Schizonepetae of 7 parts of Radix Angelicae Sinensis of Radix Notoginseng
12 parts of Radix Sophorae Flavescentiss
By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
Clinical data:
The present invention is example with the diabetic skin pruritus, through 6 routine clinical observations.Selecting traditional Chinese medical science diabetic skin pruritus is standard: diabetics is deficient serious, and limbs are weak, skin pruritus, obstinate, influence sleep.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 4 examples, women's 2 examples do not have other serious disease, and the age is 44 years old-81 years old, 63.8 years old mean age.
Efficacy determination:
1, produce effects: body constitution strengthens, and extremity are strong; Pruritus is obviously alleviated, and sleep improves.
2, effective: on one's body energetically, the pruritus degree alleviates.
3, invalid: the disease no change.
During clinical experiment, except that the necessary antidiabetic drug of diabetics is taken as usual, withdraw other medicines and health nutrient.Take Chinese medicinal capsule of the present invention, observing 2 months is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine fine powder and extract 0.28 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 2 months after, symptom is obviously improved.Clinical experiment 6 in, produce effects 3 people, effective 2 people, invalid 1 people, total effective rate 83.3%.
Claims (1)
1. Chinese medicine for the treatment of diabetic skin pruritus, it is characterized in that: it is to make with the component of following weight ratio: Radix Asparagi 5-15 part, Fructus Mori 6-18 part, Ganoderma 6-18 part, Radix Notoginseng 3-9 part, Radix Angelicae Sinensis 6-18 part, Herba Schizonepetae 5-15 part, Radix Sophorae Flavescentis 5-15 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105659746A CN102091218A (en) | 2010-11-25 | 2010-11-25 | Traditional Chinese medicine for treating diabetic skin pruritus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105659746A CN102091218A (en) | 2010-11-25 | 2010-11-25 | Traditional Chinese medicine for treating diabetic skin pruritus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102091218A true CN102091218A (en) | 2011-06-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105659746A Pending CN102091218A (en) | 2010-11-25 | 2010-11-25 | Traditional Chinese medicine for treating diabetic skin pruritus |
Country Status (1)
| Country | Link |
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| CN (1) | CN102091218A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102389460A (en) * | 2011-07-30 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic pruritus |
-
2010
- 2010-11-25 CN CN2010105659746A patent/CN102091218A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102389460A (en) * | 2011-07-30 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic pruritus |
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| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110615 |