CN102114184A - Chinese medicine for treating diabetic skin pruritus - Google Patents

Abstract

The invention relates to a Chinese medicine for treating diabetic skin pruritus, belonging to the field of Chinese medicines for treating diabetes and aiming to provide a good efficacy and a quick effect. The Chinese medicine is prepared from fragrant solomonseal rhizome, mulberry, ganoderma, panax notoginseng, Chinese angelica, schizonepeta, sophora flavescens and other raw materials. The Chinese medicine has effects of strengthening body resistance, invigorating qi, nourishing blood, promoting blood circulation, removing blood stasis, clearing heat, eliminating dampness, dispelling wind and arresting itching and the advantages of remarkable action, definite efficacy and quicker effect.

Description

A kind of Chinese medicine for the treatment of diabetic skin pruritus

Technical field

The invention belongs to the field of Chinese medicines of treatment diabetes.

Background technology

Diabetic skin pruritus is one of diabetes common complication, has 1/5 diabetes patient to suffer from this disease approximately.This pruritus is a kind of general, and very obstinate.The present Chinese medicine that is intended to treat diabetic skin pruritus, the deficiency that has two aspects: the one, effect is obvious inadequately, the 2nd, it is slower to take effect, owing to can not get the active drug treatment, the patient is standing the torment of pruritus throughout the year---and whole body is very itched unbearable, is difficult to stand, all night scratching, have difficulty in going to sleep, patient and family members thereof are very dissatisfied to this.

At problem set forth above, the invention provides a kind of Chinese medicine for the treatment of diabetic skin pruritus, it is obvious inadequately that it can solve in this type of treatment by Chinese herbs in the past effect, the slower problem that takes effect, effective, instant effect, it is remarkable to have effect, drug effect is definite, the advantage of quick result.

Summary of the invention

The present invention is achieved through the following technical solutions:

1, a kind of Chinese medicine for the treatment of diabetic skin pruritus adopts the raw material of Chinese medicine preparation, and filling a prescription is (by weight):

Rhizoma Polygonati Odorati 5---18 parts in 15 portions of Fructus Moris 6---18 portions of Ganodermas 6---

Radix Notoginseng 3---15 parts of 9 parts of Radix Angelicae Sinensis 6---18 portions of Herba Schizonepetae 5---

Radix Sophorae Flavescentis 5---15 parts

The Chinese medicine of this treatment diabetic skin pruritus is made by following method:

(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is as follows: Ganoderma is broken into graininess, cross 40 mesh sieves →, concentrate → mixed, leave standstill 10-12 hours, centrifugal → as to add 75% ethanol with 95% ethanol of 3 times of volumes with hot water (95 ℃) lixiviate of 1:20 → lixiviating solution decompression, precipitate polysaccharide → dry the ganoderan extract fine powder;

(2) by above-mentioned weight ratio, Rhizoma Polygonati Odorati, Fructus Mori, Radix Angelicae Sinensis, Herba Schizonepetae, Radix Sophorae Flavescentis are extracted through conventional water extraction process, make extract extractum fine powder;

(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, make Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.

The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think that the pathogenesis of diabetic skin pruritus is the microangiopathies and the tissue local ischemia of skin at research.The diabetics hypoimmunity, production of dryness-heat in the interior, blood is sticky, and blood flow is not smooth, and microcirculation disturbance appears in skin, blood supply insufficiency, pruritus is given birth to therefrom.Ganoderma, Fructus Mori the body resistance strengthening and constitution consolidating among the we, benefiting QI and nourishing blood, tranquilizing by nourishing the heart, enhancing human body immunity power; Radix Angelicae Sinensis, Radix Notoginseng passage, nourishing blood, blood circulation promoting and blood stasis dispelling, Ganoderma, Fructus Mori and Radix Angelicae Sinensis, Radix Notoginseng are associated with, the prosperous hemapodium of gas, " removing " of immunity and " reparation " effect promote blood clean, and no longer sticky, microcirculation improves, and blood supply is full, and this is the key of treatment primary disease; Minister is with Rhizoma Polygonati Odorati nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst; Be aided with the Radix Sophorae Flavescentis heat clearing and damp drying, kind stubborn dermatitis, the pudendal pruritus controlled; Herba Schizonepetae a surname saturating sending out of loosing, dispelling wind for relieving itching, the two share, and specially controls damp and hot pathogenic wind toxic and attacks in the pruritus of skin unbearably.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, the merit of dispelling wind for relieving itching, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.

The specific embodiment

By following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

Rhizoma Polygonati Odorati 60 gram Fructus Moris 70 kairine sesames 70 grams

Radix Notoginseng 30 gram Radix Angelicae Sinensis 70 gram Herba Schizonepetae 60 grams

Radix Sophorae Flavescentis 60 grams

Weight is extracted Ganoderma with decoction and alcohol sedimentation technique in accordance with regulations; With conventional water extraction process Rhizoma Polygonati Odorati, Fructus Mori, Radix Angelicae Sinensis, Herba Schizonepetae, Radix Sophorae Flavescentis are extracted, make extract fine powder 78 grams altogether, Radix Notoginseng is ground into fine powder, mix with said extracted thing fine powder, stir, make fine particle, the capsule of packing into No. 0, make 385 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

2, get following prescription (weight is unit by gram):

Rhizoma Polygonati Odorati 100 gram Fructus Moris 120 kairine sesames 120 grams

Radix Notoginseng 60 gram Radix Angelicae Sinensis 120 gram Herba Schizonepetae 100 grams

Radix Sophorae Flavescentis 100 grams

By above-mentioned same method, make 685 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

3, get following prescription (weight is unit by gram):

Rhizoma Polygonati Odorati 150 gram Fructus Moris 180 kairine sesames 180 grams

Radix Notoginseng 80 gram Radix Angelicae Sinensis 180 gram Herba Schizonepetae 150 grams

Radix Sophorae Flavescentis 150 grams

By above-mentioned same method, make 992 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

4, get following prescription (by weight):

6 parts of 6 portions of Ganodermas of 5 portions of Fructus Moris of Rhizoma Polygonati Odorati

5 parts of 6 portions of Herba Schizonepetae of 3 parts of Radix Angelicae Sinensis of Radix Notoginseng

5 parts of Radix Sophorae Flavescentiss

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

5, get following prescription (by weight):

16 parts of 16 portions of Ganodermas of 12 portions of Fructus Moris of Rhizoma Polygonati Odorati

12 parts of 16 portions of Herba Schizonepetae of 7 parts of Radix Angelicae Sinensis of Radix Notoginseng

12 parts of Radix Sophorae Flavescentiss

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

Clinical data:

The present invention is example with the diabetic skin pruritus, through 6 routine clinical observations.Selecting traditional Chinese medical science diabetic skin pruritus is standard: diabetics is deficient serious, and limbs are weak, skin pruritus, obstinate, influence sleep.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 4 examples, women's 2 examples do not have other serious disease, and the age is 44 years old-81 years old, 63.8 years old mean age.

Efficacy determination:

1, produce effects: body constitution strengthens, and extremity are strong; Pruritus is obviously alleviated, and sleep improves.

2, effective: on one's body energetically, the pruritus degree alleviates.

3, invalid: the disease no change.

During clinical experiment, except that the necessary antidiabetic drug of diabetics is taken as usual, withdraw other medicines and health nutrient.Take Chinese medicinal capsule of the present invention, observing 2 months is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine fine powder and extract 0.28 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 2 months after, symptom is obviously improved.6 philtrums of clinical experiment, produce effects 3 people, effective 2 people, invalid 1 people, total effective rate 83.3%.

Claims (1)

1. Chinese medicine for the treatment of diabetic skin pruritus, it is characterized in that: it is to make with the component of following weight ratio: Rhizoma Polygonati Odorati 5---15 parts, Fructus Mori 6---18 parts, Ganoderma 6---18 parts, Radix Notoginseng 3---9 parts, Radix Angelicae Sinensis 6---18 parts, Herba Schizonepetae 5---15 parts, Radix Sophorae Flavescentis 5---15 parts.