CN102641517B - Amorphous hydrocolloid dressing - Google Patents
Amorphous hydrocolloid dressing Download PDFInfo
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- CN102641517B CN102641517B CN 201110344631 CN201110344631A CN102641517B CN 102641517 B CN102641517 B CN 102641517B CN 201110344631 CN201110344631 CN 201110344631 CN 201110344631 A CN201110344631 A CN 201110344631A CN 102641517 B CN102641517 B CN 102641517B
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- hydrocolloid dressing
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Abstract
The invention discloses amorphous hydrocolloid dressing formed by high-energy ray irradiation proper crosslinking. The amorphous hydrocolloid dressing disclosed by the invention has good deformability, film forming property, moisture retention, biocompatibility and wound healing facilitation, and can protect various surgical incisions, cover various acute and chronic wounds and wound surfaces, prevent infection, accelerate healing and relive cicatrization. The amorphous hydrocolloid dressing is suitable for the filling covering protection on various wounds with tissue defects and for the protection and treatment of the surgical incisions and burns and scales including the wound surfaces formed by chemical burns as well as various acute and chronic wounds and wound surfaces. Moreover, through radiation sterilization, the amorphous hydrocolloid dressing can be stored for a long time. The formula of the amorphous hydrocolloid dressing disclosed by the invention comprises the following components in percentage by weight: 2-8% of sodium carboxymethylcellulose, 1-6% of chitosan and the balance of water. The amorphous hydrocolloid dressing also can comprise 0.1-0.3% of silver nitrate or silver chloride, 3-8% of polyvinyl alcohol, 15-25% of propylene glycol and the like all by weight. The amorphous hydrocolloid dressing is subjected to high-energy ray irradiation proper crosslinking and sterilization, thus the irradiation dose is 5-15KGy.
Description
Technical field
The present invention relates to a kind ofly be applicable to that the damaged wound of various accompanied by tissue is filled covering protection and operative incision, burn and scald comprises wound surface, various acute and chronic wounds, the protection of wound surface and the filling dressing for the treatment of that chemical burn forms, and specifically is a kind of amorphous bearing hydrocolloid dressing.
Background technology
Being used for the protection of various operative incisions, wound and wound surface and the composite medical dressing for the treatment of at present mainly contains following several:
(1) applies medical pressure-sensitive adhesive at back lining materials such as polrvinyl chloride, polyethylene, polypropylene, non-woven fabrics polyurethane, the film that makes is directly sticked on the wound surface as medical dressing.
(2) three layers of compound medical dressing use ventilative continuous film as the protection backing layer usually; Non-woven fabrics, foamed materials or fabric etc. are as the occlusion backing layer; With the adhesion layer of skin adhesion totally three layers be composited.
(3) glue build based composite dressing for medical use.This class dressing is composited by several parts such as continuous ventilated membrane, non-woven fabrics or fabric skeleton, lamellar hydrocolloid, adhesive usually.
Though existing these wound dressings have solved problems such as absorption transudate, breathability, obstruct antibacterial, waterproof, wound comfort level, but all has fixed shape, wound surface for all kinds of traumatic wounds is difficult to cover and operation comprehensively, can't fill covering for damaged wound especially.Therefore amorphous dressing had vast demand.
Summary of the invention
The object of the present invention is to provide a kind of have good deformation behavior, film property, moisture retention, biocompatibility and wound healing facilitation; can protect all kinds of operative incisions; cover various acute, chronic wounds, wound surface, prevention infection, healing acceleration also alleviate synulotic amorphous bearing hydrocolloid dressing.
Amorphous bearing hydrocolloid dressing of the present invention forms through high-energy ray irradiation is appropriately crosslinked, and the irradiation dose scope is 5KGy-15KGy.
Amorphous bearing hydrocolloid dressing of the present invention is to comprise sodium carboxymethyl cellulose 2%-8wt%, chitosan 1%-6wt% by weight percentage, and surplus is water.
Chitosan of the present invention is for water-soluble through processing.
Amorphous bearing hydrocolloid dressing of the present invention can also contain 0.1%-0.3wt% silver nitrate or silver chloride by weight percentage.
Amorphous bearing hydrocolloid dressing of the present invention can also contain by weight percentage the 3%-8% polyvinyl alcohol to improve film property.
Amorphous bearing hydrocolloid dressing of the present invention can also contain 15%-25wt% propylene glycol by weight percentage.
Amorphous bearing hydrocolloid dressing of the present invention has good deformation nature and filming performance, can fill all kinds of otch, wound and wound surface quickly and easily to cover.The effect that institute's chitosan-containing component also has hemostasis, promotes wound healing and alleviate cicatrix.
The specific embodiment
Embodiment 1:
Take by weighing sodium carboxymethyl cellulose 200 gram, chitosan 150 grams, add 4650 gram water, quietly after the abundant stirring and dissolving of constant temperature blender cause 30 minutes, solution is taken out in the adding filling machine, be respectively charged in 100 milliliters of plastic tubes and seal, put into the irradiation 10KGy of irradiation chamber of cobalt source, after the taking-up namely.
Embodiment 2:
Take by weighing sodium carboxymethyl cellulose 150 grams, chitosan 200 grams, silver nitrate or silver chloride 0.5 gram, add 4649.5 gram water, quietly after the abundant stirring and dissolving of constant temperature blender cause 30 minutes, solution is taken out in the adding filling machine, be respectively charged in 100 milliliters of plastic tubes and seal, put into the irradiation 6KGy of irradiation chamber of cobalt source, after the taking-up namely.
Embodiment 3:
Take by weighing sodium carboxymethyl cellulose 125 grams, chitosan 175 grams, polyvinyl alcohol 150 grams, propylene glycol 1000 grams, add 3550 gram water, quietly after the abundant stirring and dissolving of constant temperature blender cause 45 minutes, solution is taken out in the adding filling machine, be respectively charged in 100 milliliters of plastic tubes and seal, put into the irradiation 15KGy of irradiation chamber of cobalt source, after the taking-up namely.
Claims (2)
1. one kind through the appropriately crosslinked amorphous bearing hydrocolloid dressing that forms of high-energy ray irradiation, it is characterized in that, described amorphous bearing hydrocolloid dressing is prepared by following method: take by weighing sodium carboxymethyl cellulose 150 grams, chitosan 200 grams, silver nitrate or silver chloride 0.5 gram, add 4649.5 gram water, after the abundant stirring and dissolving of constant temperature blender, left standstill 30 minutes, solution take out is added in the filling machine, be respectively charged in 100 milliliters of plastic tubes and seal, put into the irradiation 6KGy of irradiation chamber of cobalt source, after the taking-up namely.
2. one kind through the appropriately crosslinked amorphous bearing hydrocolloid dressing that forms of high-energy ray irradiation, it is characterized in that, described amorphous bearing hydrocolloid dressing is prepared by following method: take by weighing sodium carboxymethyl cellulose 125 grams, chitosan 175 grams, polyvinyl alcohol 150 grams, propylene glycol 1000 grams, add 3550 gram water, after the abundant stirring and dissolving of constant temperature blender, left standstill 45 minutes, solution is taken out in the adding filling machine, be respectively charged in 100 milliliters of plastic tubes and seal, put into the irradiation 15KGy of irradiation chamber of cobalt source, after the taking-up namely.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110344631 CN102641517B (en) | 2011-11-04 | 2011-11-04 | Amorphous hydrocolloid dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110344631 CN102641517B (en) | 2011-11-04 | 2011-11-04 | Amorphous hydrocolloid dressing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102641517A CN102641517A (en) | 2012-08-22 |
| CN102641517B true CN102641517B (en) | 2013-08-28 |
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| CN 201110344631 Active CN102641517B (en) | 2011-11-04 | 2011-11-04 | Amorphous hydrocolloid dressing |
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| CN (1) | CN102641517B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103127544A (en) * | 2013-03-13 | 2013-06-05 | 潘华倩 | Silver-containing chitosan dressing as well as preparation method and application thereof |
| CN103191461B (en) * | 2013-04-26 | 2015-09-16 | 华熙福瑞达生物医药有限公司 | A kind of containing hyaluronic wound care dressing |
| CN104382915B (en) * | 2014-10-28 | 2017-06-16 | 天津嘉氏堂科技有限公司 | A kind of wound repair hydrocolloid |
| CN106474526B (en) * | 2015-08-28 | 2019-08-06 | 贵州扬生医用器材有限公司 | A kind of amorphous bearing hydrocolloid dressing and preparation method thereof containing liposome |
| CN105363065A (en) * | 2015-11-13 | 2016-03-02 | 邢月军 | Antibacterial and anti-inflammatory membrane |
| CN105311684A (en) * | 2015-11-13 | 2016-02-10 | 邢月军 | Surgical film for stopping bleeding and relieving pain |
| CN105288697A (en) * | 2015-11-13 | 2016-02-03 | 邢月军 | Medical film for surgery |
| CN105396171A (en) * | 2015-11-19 | 2016-03-16 | 耿文真 | Medical film with antisepsis and anti-inflammation effects and preparation process thereof |
| CN105327384A (en) * | 2015-11-19 | 2016-02-17 | 耿文真 | Absorbable medical biological membrane dressing and preparation method thereof |
| CN105381499A (en) * | 2015-11-19 | 2016-03-09 | 耿文真 | Medical membrane with effect of promoting wound healing and preparation process thereof |
| CN105797202B (en) * | 2016-03-23 | 2020-04-24 | 广州瑞辉生物科技股份有限公司 | Liquid band-aid and preparation method thereof |
Citations (5)
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| CN1721004A (en) * | 2004-07-15 | 2006-01-18 | 深圳市清华源兴生物医药科技有限公司 | Biological active antibiotic dressing |
| CN1944495A (en) * | 2006-09-29 | 2007-04-11 | 北京大学 | Water gel containing natural high molecule and its radiation preparing method |
| CN101569758A (en) * | 2008-12-31 | 2009-11-04 | 褚加冕 | Preparation method for medical use hydrocolloid dressing |
| US20100295219A1 (en) * | 2007-12-12 | 2010-11-25 | Ylitalo Caroline M | Methods of making shaped polymeric materials |
| CN102206355A (en) * | 2011-03-28 | 2011-10-05 | 东华大学 | Silver nanoparticle-containing bacterial cellulose membrane and preparation method thereof |
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2011
- 2011-11-04 CN CN 201110344631 patent/CN102641517B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1721004A (en) * | 2004-07-15 | 2006-01-18 | 深圳市清华源兴生物医药科技有限公司 | Biological active antibiotic dressing |
| CN1944495A (en) * | 2006-09-29 | 2007-04-11 | 北京大学 | Water gel containing natural high molecule and its radiation preparing method |
| US20100295219A1 (en) * | 2007-12-12 | 2010-11-25 | Ylitalo Caroline M | Methods of making shaped polymeric materials |
| CN101569758A (en) * | 2008-12-31 | 2009-11-04 | 褚加冕 | Preparation method for medical use hydrocolloid dressing |
| CN102206355A (en) * | 2011-03-28 | 2011-10-05 | 东华大学 | Silver nanoparticle-containing bacterial cellulose membrane and preparation method thereof |
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| CN102641517A (en) | 2012-08-22 |
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Application publication date: 20120822 Assignee: Beijing utrust Haibo technology development Limited by Share Ltd Assignor: Zhou Yeping Contract record no.: 2015990000408 Denomination of invention: Amorphous hydrocolloid dressing Granted publication date: 20130828 License type: Exclusive License Record date: 20150602 |
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