CN102631471A - Health care product recipe for reducing blood glucose and preventing and curing diabetic complications - Google Patents
Health care product recipe for reducing blood glucose and preventing and curing diabetic complications Download PDFInfo
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- CN102631471A CN102631471A CN2012101389605A CN201210138960A CN102631471A CN 102631471 A CN102631471 A CN 102631471A CN 2012101389605 A CN2012101389605 A CN 2012101389605A CN 201210138960 A CN201210138960 A CN 201210138960A CN 102631471 A CN102631471 A CN 102631471A
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Abstract
The invention relates to a health care product recipe for reducing blood glucose and preventing and curing diabetic complications. The health care product recipe is developed for crowd in IGT (impaired glucose tolerance) states, crowd suffering from impaired fasting blood glucose and crowd with diabetes. A condensed pill is prepared by five-flavor compatibility of a sea-buckthorn seed proanthocyanidin extractive, a sea-buckthorn pericarp ursolic acid extractive, fresh sea-buckthorn pulp, a cortex lycii radicis extractive and a coptis chinensis extractive, and has the functions of reducing the blood glucose and interfering insulin secretion as well as blood pressure, blood fat, blood viscosity and insulin resistance. The health care product produced according to the health care product recipe provided by the invention is used for reducing the blood glucose and preventing the diabetic complications and the exacerbation of the complications for the crowd in the IGT states, the crowd suffering from the impaired fasting blood glucose and the crowd with the diabetes.
Description
Technical field:
The present invention relates to the reduction and the control diabetic complication function of blood glucose IGT state crowd, impaired fasting glucose crowd and diabetic population blood glucose, for it develops the concentrated pill that seed of Fructus Hippophae procyanidin extract, seabuckthorn fruit peel ursolic acid extract, fresh syrup of Fructrs Hippophae, Cortex Lycii extract and Rhizoma Coptidis extract compatibility are processed specially.
Background technology:
The latest survey data show that discloses according to General Board professor Yang Wenying of diabetes branch of Chinese Medical Association, at present, China more than 20 years old crowd's onset diabetes rate reached 9.7%, the prediabetes sickness rate is up to 15.5%.Can estimate China's diabetes number thus and exceed 9,000 ten thousand, the prediabetes number then surpasses 100,000,000.Thrilling these data be!
Western medicine though the diabetes acute complications is obviously reduced, has been died from chronic complication person and has been got more and more since the invention insulin.And primary disease is wanted blood sugar control, need take medicine all the life, and the medicine of these chemosynthesis is taken for a long time, certainly will damage Liver and kidney, the treatment of primary disease and prognosis, and situation is severe.Why can be like this? Trace it to its cause and just be: our treatment is to suit the medicine to the illness always, and not to its cause of disease.Because western medicine does not find the pathogenetic basic reason of glycosuria.Diabetes are situation occurred frequently at present, and key is the harm insufficient recognition to early stage IGT state, and the intervention of so-called life style is an empty verbiage often, has ignored the effective intervention to prediabetes (IGT state) crowd.
Effective control of diabetes; Its key is the emphasis reach with its intervention; And be comprehensive intervention, promptly seek effective prescription, prevention and reverting diabetes are the crowd of the clinical IGT of being referred to as state in earlier stage; Promptly not only blood glucose and secretion of insulin to be intervened, the opposing of blood pressure, blood fat, blood viscosity and the insulin of blood will be intervened simultaneously.
Seed of Fructus Hippophae procyanidin extract, seabuckthorn fruit peel ursolic acid extract, fresh syrup of Fructrs Hippophae, Cortex Lycii extract and Rhizoma Coptidis extract are used to develop blood sugar lowering and control diabetic complication concentrated pill health product still belong to blank.
Goal of the invention:
The object of the invention is to provide a kind of blood sugar lowering and control diabetic complication health product, and preparation method thereof.Technical scheme of the present invention is following:
Prescription:
The health product of a kind of blood sugar lowering and control diabetic complication; It is characterized in that: by seed of Fructus Hippophae procyanidin extract 10 grams-300 grams; Seabuckthorn fruit peel ursolic acid extract 20 grams-350 grams, fresh syrup of Fructrs Hippophae 500 grams-3500 grams, Cortex Lycii extract 8 grams-50 grams; Rhizoma Coptidis extract 3 grams-20 grams, starch (adjuvant) 100 grams-200 grams.Process 1000 of the concentrated pills of 0.1 gram/ball-0.5 gram/ball.
The seed of Fructus Hippophae procyanidin extract: for the seed of medicine-food two-purpose kind Fructus Hippophae through supercritical CO
2Sea-buckthorn seed cake behind the extraction Fructrs Hippophae seed oil, through the extract that the edible ethanol leach at low temperature obtains, this extract is main bioactive ingredients with the Fructus Hippophae procyanidin.The pharmacological actions that keep healthy widely such as the seed of Fructus Hippophae procyanidin extract has antioxidation, removes free radical, mutation, anticancer, antiinflammatory, antiallergic, antiviral, blood fat reducing, anticoagulant, antithrombotic, blood sugar lowering and enhancing immunity.
Seabuckthorn fruit peel ursolic acid extract: for the peel of medicine-food two-purpose kind Fructus Hippophae through supercritical CO
2Seabuckthorn fruit peel slag behind the extraction Fructus Hippophae haze wax, through the extract that the edible ethanol leach at low temperature obtains, this extract is main bioactive ingredients with the Fructus Hippophae ursolic acid.Seabuckthorn fruit peel ursolic acid extract has health care pharmacological actions such as antioxidation, antiinflammatory, mutation, antiviral, anticancer, blood sugar lowering, liver detoxification.
Fresh syrup of Fructrs Hippophae: the juice of Fructus Hippophae that obtains through squeezing for medicine-food two-purpose kind sea-buchthorn fresh fruit.Contain biological activities such as multivitamin, several amino acids, multiple organic acid, flavone compound, phytosterin compound, polyphenol compound and various trace elements in the fresh syrup of Fructrs Hippophae.Have the pharmacological actions that keep healthy widely such as blood fat reducing, reducing blood viscosity, antiplatelet aggregation, antithrombotic, cardiac function enhancing, blood sugar lowering, hepatoprotective and enhancing immunity.
Cortex Lycii extract: the extract that obtains through water extraction for the dry root bark of matrimony vine of solanaceae plant.Contain alkaloids, sterol, glycoside, peptide class, taurine, vanillic acid etc. in the Cortex Lycii extract.Cortex Lycii extract has blood sugar lowering, blood pressure lowering, immunomodulating, biological action such as antibiotic.
Rhizoma Coptidis extract: the extract that obtains through ethanol extraction for ranunculaceae plant Coptis deltoidea C.Y.Cheng et Hsiao and Coptis Teeta Wall rhizome.Contain berberine (another name berberine), coptisine, 13-methyl-.psi.-coptisine., ferulic acid, chlorogenic acid etc. in the Rhizoma Coptidis extract.Rhizoma Coptidis extract has pharmacological actions widely such as blood sugar lowering, blood fat reducing, anticoagulant, arrhythmia, antiviral.
The compatibility explanation:
Seed of Fructus Hippophae procyanidin extract, seabuckthorn fruit peel ursolic acid extract, fresh syrup of Fructrs Hippophae all are that medicine-food two-purpose kind Fructus Hippophae extraction separation makes.Cortex Lycii, Rhizoma Coptidis are the kind that allows interpolation in the health product rules.The Fructus Hippophae extract hypoglycemic activity possibly be that its powerful oxidation resistance of active component in procyanidin, ursolic acid and the fresh syrup of Fructrs Hippophae Cytotoxic effect of β, the effect of repairing pancreas tissue oxidizing damage that can effectively resist reactive oxygen free radical and cause and the effect of regulating immunity of organisms are relevant.Experimentation confirms that taurine is one of hypoglycemic effective ingredient of Cortex Lycii.Berberine in the Rhizoma Coptidis maybe be through suppressing gluconeogenesis or promoting that glycolysis produces hypoglycemic activity.
Its processing method is:
Purify the concentrated pill workshop at 100,000 grades, with seed of Fructus Hippophae procyanidin extract, seabuckthorn fruit peel ursolic acid extract, Cortex Lycii extract, Rhizoma Coptidis extract, starch (adjuvant) mix homogeneously in powder mixer in the prescription; The powder of mix homogeneously is added in the cream powder mixer, add the fresh syrup of Fructrs Hippophae condensed cream again and be mixed uniformly; The material that again the cream powder is mixed uniformly adds concentrated pill pellet processing machine pill, whole ball, drying, quality inspection, packing.For use.
Useful result of the present invention:
Prescription with seed of Fructus Hippophae procyanidin extract, seabuckthorn fruit peel ursolic acid extract, fresh syrup of Fructrs Hippophae, Cortex Lycii extract and Rhizoma Coptidis extract compatibility one-tenth; The concentrated pill of processing; Tool is with the effect of obvious blood sugar lowering and control diabetic complication; Have the effect of intervening blood pressure, blood fat, blood viscosity simultaneously, and without any side effects.Can be used for prediabetes (being the IGT state) crowd's intervention, also be applicable to the diabetic population blood sugar lowering and prevent and treat the intervention of complication.
The specific embodiment:
Embodiment 1: get fresh syrup of Fructrs Hippophae 15kg, negative pressure is concentrated into the thick paste of relative density＞1.35 (25 ℃), seed of Fructus Hippophae procyanidin extract 0.12kg; Seabuckthorn fruit peel ursolic acid extract 0.26kg; Cortex Lycii extract 0.22kg, Rhizoma Coptidis extract 0.04kg, starch (adjuvant) 0.61kg.Concentrated pill workshop 100,000 grades of purifications; With the seed of Fructus Hippophae procyanidin extract 0.12kg in the above-mentioned prescription, seabuckthorn fruit peel ursolic acid extract 0.26kg, Cortex Lycii extract 0.22kg; Rhizoma Coptidis extract 0.04kg; After being mixed uniformly in starch (adjuvant) the 0.61kg adding high efficient mixed machine, put into cream powder mixer again, progressively add the fresh syrup of Fructrs Hippophae thick paste and mix system more than 2 hours; The cream powder mixes to stir well puts into the concentrated pill that the concentrated pill pellet processing machine is processed diameter 3mm after even, and theoretical yield is 13000 (dry back ball weighs 0.3 gram/grain).Whole ball, drying, inspection ball, bottling, quality inspection, outer package.For use.Process a kind of concentrated pill of prescription.
Embodiment 2: get fresh syrup of Fructrs Hippophae 25kg, negative pressure is concentrated into the thick paste of relative density＞1.35 (25 ℃), seed of Fructus Hippophae procyanidin extract 0.2kg; Seabuckthorn fruit peel ursolic acid extract 0.45kg; Cortex Lycii extract 0.36kg, Rhizoma Coptidis extract 0.06kg, starch (adjuvant) 1.00kg.Concentrated pill workshop 100,000 grades of purifications; With the seed of Fructus Hippophae procyanidin extract 0.2kg in the above-mentioned prescription, seabuckthorn fruit peel ursolic acid extract 0.45kg, Cortex Lycii extract 0.36kg; Rhizoma Coptidis extract 0.06kg; After being mixed uniformly in starch (adjuvant) the 1.00kg adding high efficient mixed machine, put into cream powder mixer again, progressively add the fresh syrup of Fructrs Hippophae thick paste and mix system more than 2 hours; Put into the concentrated pill pellet processing machine after the cream powder is mixed uniformly and process the concentrated pill of diameter 2.5mm, theoretical yield is 26000 (dry back ball weighs 0.25 gram/grain).Whole ball, drying, inspection ball, bottling, quality inspection, outer package.For use.Process a kind of concentrated pill of prescription.
Effective component and content:
Every 100g contains Fructus Hippophae total flavones (rutin meter) >=400mg, Fructus Hippophae procyanidin >=1.4g, Fructus Hippophae ursolic acid >=1g
Suitable crowd:
Blood glucose IGT state crowd, impaired fasting glucose crowd, diabetic population
Method for using and consumption
One after each meal
0.3g/ grain, every day three times, each 20
Or the 0.25g/ grain, every day three times, each 24
Description of drawings:
Accompanying drawing is a process diagram of the present invention.
Claims (4)
1. the concentrated pill health product of blood sugar lowering and control diabetic complication; It is characterized in that: by seed of Fructus Hippophae procyanidin extract 10 grams-300 grams; Seabuckthorn fruit peel ursolic acid extract 20 grams-350 grams, fresh syrup of Fructrs Hippophae 500 grams-3500 grams, Cortex Lycii extract 8 grams-50 grams; Rhizoma Coptidis extract 3 grams-20 grams, starch (adjuvant) 100 grams-200 grams.Process 1000 of the concentrated pills of 0.1 gram/ball-0.5 gram/ball.
2. require the concentrated pill health product of described a kind of blood sugar lowering and control diabetic complication like right 1, it is characterized in that: the seed of Fructus Hippophae procyanidin extract is that seed of Fructus Hippophae is through supercritical CO
2The seed dregs of rice behind the seed oil are extracted in extraction, adopt edible ethanol to extract and make.There is document that the seed of Fructus Hippophae procyanidin extract is expressed as the seed of Fructus Hippophae proanthocyanidin extract.
3. require the concentrated pill health product of described a kind of blood sugar lowering and control diabetic complication like right 1, it is characterized in that: seabuckthorn fruit peel ursolic acid extract is that seabuckthorn fruit peel is through supercritical CO
2The peel residue behind the peel oil is extracted in extraction, adopts edible ethanol to extract and makes.
4. require the concentrated pill health product of described a kind of blood sugar lowering and control diabetic complication like right 1, it is characterized in that: the paste of (25 ℃) goes to be mixed and made into concentrated pill with powder fresh syrup of Fructrs Hippophae through negative pressure cryoconcentration to relative density＞1.15.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102823866A (en) * | 2012-09-20 | 2012-12-19 | 北京宝得瑞食品有限公司 | Dietetic therapy product of sea-buckthorn lotus leaf juice for conditioning blood fat, reducing blood viscosity and improving myocardial blood |
| CN109106733A (en) * | 2017-06-22 | 2019-01-01 | 陕西天奎生物医药科技有限公司 | A kind of composition for preventing and treating diabetes and/or vascular complication disease, drug or health care product and its application |
| CN110037258A (en) * | 2019-04-15 | 2019-07-23 | 北京宝得瑞健康产业有限公司 | A kind of anti-sea-buckthorn compound superfine powder and its preparation method for being mutated, pressing down cancer and cancer cell specific induction of apoptosis |
| CN110559322A (en) * | 2018-06-06 | 2019-12-13 | 邹玮 | Sea-buckthorn compound hard capsule for treating depression and preventing anxiety depression and preparation method thereof |
| CN110623998A (en) * | 2019-09-11 | 2019-12-31 | 中国中医科学院中医临床基础医学研究所 | Traditional Chinese medicine composition for diabetic peripheral neuropathy and application thereof |
-
2012
- 2012-05-08 CN CN2012101389605A patent/CN102631471A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102823866A (en) * | 2012-09-20 | 2012-12-19 | 北京宝得瑞食品有限公司 | Dietetic therapy product of sea-buckthorn lotus leaf juice for conditioning blood fat, reducing blood viscosity and improving myocardial blood |
| CN109106733A (en) * | 2017-06-22 | 2019-01-01 | 陕西天奎生物医药科技有限公司 | A kind of composition for preventing and treating diabetes and/or vascular complication disease, drug or health care product and its application |
| CN110559322A (en) * | 2018-06-06 | 2019-12-13 | 邹玮 | Sea-buckthorn compound hard capsule for treating depression and preventing anxiety depression and preparation method thereof |
| CN110037258A (en) * | 2019-04-15 | 2019-07-23 | 北京宝得瑞健康产业有限公司 | A kind of anti-sea-buckthorn compound superfine powder and its preparation method for being mutated, pressing down cancer and cancer cell specific induction of apoptosis |
| CN110623998A (en) * | 2019-09-11 | 2019-12-31 | 中国中医科学院中医临床基础医学研究所 | Traditional Chinese medicine composition for diabetic peripheral neuropathy and application thereof |
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Application publication date: 20120815 |