CN102631416A - Traditional Chinese medicine for treating diabetic skin itch - Google Patents
Traditional Chinese medicine for treating diabetic skin itch Download PDFInfo
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- CN102631416A CN102631416A CN2012100952956A CN201210095295A CN102631416A CN 102631416 A CN102631416 A CN 102631416A CN 2012100952956 A CN2012100952956 A CN 2012100952956A CN 201210095295 A CN201210095295 A CN 201210095295A CN 102631416 A CN102631416 A CN 102631416A
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Abstract
Description
技术领域 technical field
本发明属于治疗糖尿病的中药领域。 The invention belongs to the field of traditional Chinese medicine for treating diabetes.
背景技术 Background technique
糖尿病性皮肤瘙痒是糖尿病常见的并发症之一,约有1/5的糖尿病人患有此症。这种瘙痒是一种全身性的,而且非常顽固。目前的旨在治疗糖尿病性皮肤瘙痒的中药,存在两个方面的不足:一是效果不够明显,二是见效比较迟缓,由于得不到有效药治疗,患者常年忍受着瘙痒的折磨——全身奇痒钻心,难以忍受,彻夜抓挠,难以入睡,患者及其家属对此很不满意。 Diabetic skin itching is one of the common complications of diabetes, and about 1/5 of diabetics suffer from it. This itching is generalized and very persistent. The current traditional Chinese medicine aimed at treating diabetic skin itching has two deficiencies: one is that the effect is not obvious enough; The itching is unbearable, scratching all night, and it is difficult to fall asleep. The patient and his family are very dissatisfied with this.
针对以上提出的问题,本发明提供一种治疗糖尿病性皮肤瘙痒的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。 Aiming at the problems raised above, the present invention provides a traditional Chinese medicine for treating diabetic skin itching, which can solve the problem that the effect of traditional Chinese medicines in the past is not obvious enough, and the effect is relatively slow. Exactly, the advantage of quicker effect.
发明内容 Contents of the invention
本发明是通过以下技术方案来实现的: The present invention is achieved through the following technical solutions:
1、一种治疗糖尿病性皮肤瘙痒的中药,采用中药原料制备,中药原料的重量配比为: 1, a kind of Chinese medicine for treating diabetic skin pruritus, adopts Chinese medicine raw material to prepare, and the weight ratio of Chinese medicine raw material is:
大青叶4——12份 桑椹6——18份 灵芝6——18份 Folium Folium 4—12 parts Mulberry 6—18 parts Ganoderma lucidum 6—18 parts
三七1——3份 当归6——18份 荆芥3——9份 Panax notoginseng 1—3 servings Angelica 6—18 servings Nepeta 3—9 servings
苦参3——9份 Sophora flavescens 3 - 9 parts
这种治疗糖尿病性皮肤瘙痒的中药是由下列方法制成的: This traditional Chinese medicine for diabetic skin itching is made by the following methods:
(1)按上述重量比,将大青叶、桑椹、灵芝、当归、荆芥、苦参经常规水提取工艺提取,制成浸膏,烘干粉碎,得提取物细粉; (1) According to the above weight ratio, extract Folium Folium Folium, Mulberry, Ganoderma lucidum, Angelica, Schizonepeta, and Sophora flavescens through a conventional water extraction process to make an extract, dry and pulverize it to obtain a fine powder of the extract;
(2)按上述重量比,将三七研成细粉,与上述(1)提取物细粉混合,搅拌均匀,制成中药颗粒剂、胶囊剂、片剂。 (2) Grind notoginseng into fine powder according to the above weight ratio, mix with the fine powder of the extract from (1) above, and stir evenly to make traditional Chinese medicine granules, capsules, and tablets.
本发明根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。我们研究认为,糖尿病性皮肤瘙痒的发病机制,是皮肤的微血管病变和组织局部缺血。糖尿病患者免疫力低下,燥热内生,血液黏稠,血液流动不畅,皮肤出现微循环障碍,供血不足,瘙痒由此而生。本方之中灵芝、桑椹扶正培本,益气养血,养心安神,增强机体免疫力;当归、三七生血养血,活血化瘀,灵芝、桑椹与当归、三七为伍,气旺血足,免疫力的“清除”和“修复”作用促进血液清洁,不再黏稠,微循环改善,供血充盈,此为治疗本病的关键;臣以大青叶清热解毒,兼能凉血;辅以苦参清热燥湿,善治顽癣、阴痒;荆芥宣散透发,祛风止痒,二者合用,专治湿热风毒攻于皮肤之瘙痒难忍。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,清热燥湿,祛风止痒之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。 The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. Our research suggests that the pathogenesis of diabetic pruritus is skin microvascular lesions and tissue ischemia. Diabetic patients have low immunity, endogenous dryness, thick blood, poor blood flow, microcirculation disorder in the skin, insufficient blood supply, and itching. In this prescription, Ganoderma lucidum and mulberry strengthen the body, nourish qi and blood, nourish the heart and calm the nerves, and enhance the body's immunity; Blood foot, the "clearing" and "repairing" effect of immunity promotes blood cleansing, no longer sticky, microcirculation is improved, and blood supply is filled, which is the key to the treatment of this disease; Chen uses Folium Folium to clear away heat and detoxify, and can also cool blood; Supplemented with Sophora flavescens to clear away heat and dampness, it is good at treating stubborn tinea and pruritus vulvae. All the medicines are compatible and complement each other. They play the role of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing away heat and dampness, expelling wind and relieving itching, with good effect and quick effect. advantage.
具体实施方式 Detailed ways
通过以下实施方式对本发明做具体说明: The present invention is specifically described by the following embodiments:
1、取以下配方(重量按克为单位): 1. Take the following formula (weight in grams):
大青叶400克 桑椹600克 灵芝600克 400g Folium Folium Mulberry 600g Ganoderma lucidum 600g
三七100克 当归600克 荆芥300克 100 grams of Panax notoginseng 600 grams of Angelica sinensis Nepeta 300 grams
苦参300克 Sophora flavescens 300 grams
按规定重量,用常规水提取工艺将大青叶、桑椹、灵芝、当归、荆芥、苦参提取,制成提取物细粉280克,将三七研成细粉,与上述提取物细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊1266粒,每粒胶囊内含中药细粉及提取物0.3克。 According to the specified weight, use the conventional water extraction process to extract Folium Folium, Mulberry, Ganoderma lucidum, Angelica, Schizonepeta, and Sophora flavescens to make 280 grams of fine powder of the extract. Mix and stir evenly, make fine particles, pack into No. 0 capsules, and make 1266 Chinese medicine capsules, each capsule contains Chinese medicine fine powder and 0.3 grams of extract.
2、取以下配方(重量按克为单位): 2. Take the following formula (the weight is in grams):
大青叶800克 桑椹1200克 灵芝1200克 800g Folium Folium Mulberry 1200g Ganoderma lucidum 1200g
三七180克 当归1200克 荆芥600克 Panax notoginseng 180 grams Angelica sinensis 1200 grams Nepeta 600 grams
苦参600克 Sophora flavescens 600 grams
按上述同样的方法,制成中药胶囊2466粒,每粒胶囊内含中药细粉及提取物0.3克。 By above-mentioned same method, make 2466 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
3、取以下配方(重量按克为单位): 3. Take the following formula (the weight is in grams):
大青叶1200克 桑椹1800克 灵芝1800克 1200g Folium Folium Mulberry 1800g Ganoderma lucidum 1800g
三七260克 当归1800克 荆芥900克 Panax notoginseng 260 grams Angelica sinensis 1800 grams Nepeta 900 grams
苦参900克 Sophora flavescens 900 grams
按上述同样的方法,制成中药胶囊3666粒,每粒胶囊内含中药细粉及提取物0.3克。 By above-mentioned same method, make 3666 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
4、取以下配方(按重量比): 4. Take the following formula (by weight ratio):
大青叶4份 桑椹7份 灵芝7份 4 parts Folium Folium 7 parts mulberry 7 parts Ganoderma lucidum
三七1份 当归7份 荆芥3份 1 serving of Panax notoginseng 7 servings of Angelica sinensis 3 servings of Nepeta
苦参3份 3 parts Sophora flavescens
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make Chinese medicine capsule, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
5、取以下配方(按重量比): 5. Take the following formula (by weight ratio):
大青叶9份 桑椹14份 灵芝14份 9 parts of Folium Folium 14 parts of Mulberry 14 parts of Ganoderma lucidum
三七2份 当归14份 荆芥7份 2 servings of Panax notoginseng 14 servings of Angelica sinensis 7 servings of Nepeta
苦参7份 7 parts Sophora flavescens
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.3克。 By the above-mentioned same method, make Chinese medicine capsule, every capsule contains Chinese medicine fine powder and extract 0.3 gram.
临床资料:clinical information:
本发明以糖尿病性皮肤瘙痒为例,经17例临床观察。选择中医糖尿病性皮肤瘙痒为标准:糖尿病患者虚损严重,肢体乏力,皮肤瘙痒,久治不愈,影响睡眠。如上症状,即可确诊。在确诊观察的对象中,男性9例,女性8例,无其它严重疾病,年龄为46岁—81岁,平均年龄62.7岁。 The present invention takes diabetic pruritus as an example, through clinical observation of 17 cases. TCM diabetic skin itching was selected as the standard: Diabetic patients have serious wasting, limb weakness, skin itching, long-term treatment, affecting sleep. The above symptoms can be diagnosed. Among the confirmed observation objects, there were 9 males and 8 females, without other serious diseases, ranging in age from 46 to 81 years old, with an average age of 62.7 years.
疗效判定: Judgment of curative effect:
1、显效:体质增强,四肢有力;瘙痒明显缓解,睡眠改善。 1. Significant effect: Physical fitness is enhanced, limbs are strong; itching is significantly relieved, and sleep is improved.
2、有效:身上有劲,瘙痒程度减轻。 2. Effective: the body is strengthened, and the degree of itching is relieved.
3、无效:病症无变化。 3. Ineffective: no change in symptoms.
临床实验时,停服其它药物和保健营养品。服用本发明具体实施方式2制作的中药胶囊,观察2个月为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.3克,饭后温开水送服,1个月后症状即有缓解,服用2个月后,症状明显改善。临床实验的17人中,显效9人,有效7人,无效1人,总有效率94.1%。 During the clinical trial, stop taking other medicines and health nutrition products. Take the Chinese medicine capsule that specific embodiment 2 of the present invention makes, observe 2 months and be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.3 grams of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 2 months of taking, Symptoms improved significantly. Among the 17 people in the clinical trial, 9 were markedly effective, 7 were effective, and 1 was ineffective, with a total effective rate of 94.1%.
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| CN101396454A (en) * | 2007-09-26 | 2009-04-01 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
| CN101953892A (en) * | 2010-10-14 | 2011-01-26 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic cutaneous pruritus |
| CN101961386A (en) * | 2010-09-16 | 2011-02-02 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
| CN101961387A (en) * | 2010-10-27 | 2011-02-02 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
| CN101972422A (en) * | 2010-09-29 | 2011-02-16 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic pruritus |
| CN102389478A (en) * | 2011-08-14 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic pruritus |
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2012
- 2012-03-31 CN CN2012100952956A patent/CN102631416A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006160644A (en) * | 2004-12-06 | 2006-06-22 | Maruishi Pharmaceutical Co Ltd | Capsaicin-containing external preparation |
| CN101396454A (en) * | 2007-09-26 | 2009-04-01 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
| CN101961386A (en) * | 2010-09-16 | 2011-02-02 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
| CN101972422A (en) * | 2010-09-29 | 2011-02-16 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic pruritus |
| CN101953892A (en) * | 2010-10-14 | 2011-01-26 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic cutaneous pruritus |
| CN101961387A (en) * | 2010-10-27 | 2011-02-02 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
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Application publication date: 20120815 |