CN102600300B - Externally-applied liquid medicine for treatment of pinkeye and preparation method thereof - Google Patents
Externally-applied liquid medicine for treatment of pinkeye and preparation method thereof Download PDFInfo
- Publication number
- CN102600300B CN102600300B CN201110424457.1A CN201110424457A CN102600300B CN 102600300 B CN102600300 B CN 102600300B CN 201110424457 A CN201110424457 A CN 201110424457A CN 102600300 B CN102600300 B CN 102600300B
- Authority
- CN
- China
- Prior art keywords
- lotion
- chinese liquor
- eye disease
- treatment
- folium camelliae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of medicine, and discloses externally-applied liquid medicine for treatment of pinkeye and a preparation method thereof. The externally-applied liquid medicine for the treatment of pinkeye is prepared with liquor, calcium oxide, tea leaves and sodium bicarbonate into a spray preparation, can be used conveniently and certain preventative effects on the pinkeye. The pinkeye can be treated rapidly and effectively, the raw materials can be obtained easily and inexpensive, and the prepared product has no toxic or side effects and can be applied widely.
Description
Technical field
The present invention relates to a kind of lotion for the treatment of pink eye disease, relate in particular to and a kind ofly can prevent and treat lotion of pink eye disease and preparation method thereof.
Background technology
A kind of acute infection ophthalmia of pink eye disease, according to different pathogenesiss, can be divided into bacterial conjunctivitis and viral conjunctivitis two classes, and its clinical symptoms is similar, but popularity degree and hazardness are attached most importance to viral conjunctivitis.Pink eye disease morbidity is anxious, generally in bacterial infection 1-2 days, starts morbidity, and infectiousness is strong, because immunity after curing is low, therefore can repeated infection (also can fall ill as contacted again patient), and from baby to eight old man of 90 years old of some months, all may fall ill; Popular fast, suffer from after pink eye disease, be usually that a people falls ill, at 1-2, in week, cause the wide-scale distribution such as the whole family, kindergarten, school, factory, infect large quantities of patients.
Mostly pink eye disease is the first sequela of eyes, ill early stage, and patient feels that eyes are hot, burns, photophobia, furious, conscious eyes mill pain, as entering as sand ground roll pain unbearably, and then eyelid is red and swollen, eye secretion is many, keep in dark place, shed tears, morning WA, the normal secreted thing of eyelid clings, and is difficult for opening.On some patient's conjunctivas, there is little petechia or ecchymosis, secretions is mucus purulence, sometimes on palpebral conjunctiva surface, form one deck canescence pseudomembrane, edge of cornea can have canescence to infiltrate point, and serious can be with General Symptomies such as headache, heating, fatigue, preauricular lymph nodes enlargements.
At present, the method for the treatment of pink eye disease mainly contains: suffering from discharge of eye when more, with suitable irrigation as normal saline or 2% boric acid water flushing conjunctival sac, every day 2-3 time, and clean margo palpebrae with disinfecting cotton swab.Also can be to suffering from eyespot collyrium or being coated with spongaion.As be bacterial infection, can select the most effective antibiotic eye dropping of eye drops according to the strain checking out, according to state of an illness weight, every 2-3 hour or per hour putting drops in one's eyes 1 time, conventional collyrium has 10%-20% sulphacetamide, 0.3% norfloxacin, 0.25% chloromycetin eyedrops etc., can be coated with Antibiotic Eye Ointment, as ciprofloxacin, chlortetracycline or tetracycline spongaion before sleeping evening, before each some medicine, need secretions scrub, to improve curative effect.The conjunctivitis that hybrid virus is infected, except the above Drug therapy of application, available antiviral collyrium also, as can be with 0.1% hydrobenzole collyrium, 0.1% peptide butylamine Emulsion for adenovirus, as can be with 0.1% iodouracil desoxyriboside, 0.1% acyclovir eyedrop etc. for small virus, every day 2-3 time, if desired also can application of interference element etc.But treatment time is long, easily recurrence, causes very big misery to patient.
Summary of the invention
The present invention is directed to deficiency of the prior art, provide a kind of and can prevent lotion with fast treating pink eye disease and preparation method thereof.
In order to solve the problems of the technologies described above, the present invention is solved by following technical proposals:
Treat a lotion for pink eye disease, by the preparation of raw material of following weight proportioning, formed: Chinese liquor 88-94%, calcium oxide 4-6%, Folium Camelliae sinensis 0.1-0.8%, sodium bicarbonate 1-6%.
Calcium oxide of the present invention (quicklime) is met water generation calcium hydroxide and is played disinfective action.Sodium bicarbonate (sodium bicarbonate), is commonly called as " sodium bicarbonate " or " soda powder ", and character is white powder or grain, and odorless, salty in the mouth, soluble in water, present alkalescence when water-soluble, and aqueous solution is alkalescence, can in and sour environment; The sodium bicarbonate solution of 2%-4% can Antifungi breeding.
As preferably, the weight proportion of each raw material is: Chinese liquor 90-92%, calcium oxide 4-6%, Folium Camelliae sinensis 0.3-0.6%, sodium bicarbonate 3-4%.
As preferably, the weight proportion of each raw material is: Chinese liquor 91%, calcium oxide 5%, Folium Camelliae sinensis 0.5%, sodium bicarbonate 3.5%.
As preferably, the number of degrees of described Chinese liquor are 40-50 °.In Chinese liquor, contain ethanol, have certain disinfective action.
As preferably, described Folium Camelliae sinensis is green Folium Camelliae sinensis.In green Folium Camelliae sinensis, contain tea polyphenols, caffeine, chlorophyll and vitamin.Green tea is azymic tea, and due to its characteristic natural materials in fresh leaf that determined reservation that it is more, wherein tea polyphenols, caffeine have retained the more than 85% of fresh leaf, and chlorophyll retains 50% left and right, and vitamin loss is also less.Green tea contributes to suppress and resist viral bacterium, and tea polyphenols has stronger astriction, and pathogen, virus are had to obvious inhibition and killing action.The natural materials composition retaining in green tea, has the effect of anti-aging, anti-cancer, anticancer, sterilization, antiinflammatory.
As preferably, described sodium bicarbonate is Powdered.
As preferably, described lotion is spray agent.
A preparation method for the treatment of the lotion of pink eye disease, comprises the following steps:
Step a: take by weight ratio Chinese liquor, calcium oxide, sodium bicarbonate, Folium Camelliae sinensis;
Step b: Folium Camelliae sinensis is put into the water of 180-220 times of weight, boiled, then cooling, obtain tea, standby;
Step c: calcium oxide powder is broken into powder, mixs homogeneously with sodium bicarbonate, put into reaction tank;
Steps d: add the 1%-25% of Chinese liquor in step a, furnishing paste, standing and reacting 1-2 hour;
Step e: the Chinese liquor of 75%-99% in remaining step a, all pour in reaction tank, stir, with steam boiler, be heated to, after 70-100 ℃, naturally cool to 30 ℃, obtain stock solution;
Step f: get tea and the stock solution of step b and step e, mix by the part by weight of 94:6, sedimentation and filtration twice, obtains filtrate, treats the lotion of pink eye disease.
As preferably, the Chinese liquor adding during steps d furnishing paste is the 4%-6% of Chinese liquor in step a.
According to technical scheme of the present invention, lotion of the present invention is made spray agent, easy to use; Pink eye disease is had to certain preventive effect, and treatment pink eye disease is effective fast; Use raw material is simple, low price, and the product making is used and has no side effect, and can popularly use.
The specific embodiment
Below in conjunction with embodiment, the present invention is described in further detail.
Embodiment 1
The lotion for the treatment of pink eye disease, is formed by the preparation of raw material of following weight proportioning: Chinese liquor 88g, calcium oxide 4g, Folium Camelliae sinensis 0.1g, sodium bicarbonate 1g.The number of degrees of Chinese liquor are 40 °, and Folium Camelliae sinensis is green Folium Camelliae sinensis.
The method of the lotion of preparation treatment pink eye disease comprises the following steps:
Step a: take Chinese liquor 88g, calcium oxide 4g, Folium Camelliae sinensis 0.1g, sodium bicarbonate 1g;
Step b: Folium Camelliae sinensis is put into 20mL water, boil, then cooling, obtain tea, standby;
Step c: calcium oxide powder is broken into powder, mixs homogeneously with sodium bicarbonate powder, put into reaction tank;
Steps d: add 0.88g Chinese liquor, furnishing paste, standing and reacting 1 hour;
Step e: remaining 87.12g Chinese liquor, all pour in reaction tank, stir, with steam boiler, be heated to, after 70 ℃, naturally cool to 30 ℃, obtain stock solution;
Step f: get tea and the stock solution of step b and step e, mix by the part by weight of 94:6, sedimentation and filtration twice, obtains filtrate, treats the lotion of pink eye disease.
Using method: 2-3 time on the one, a 1g.
Embodiment 2
The lotion for the treatment of pink eye disease, is formed by the preparation of raw material of following weight proportioning: Chinese liquor 94g, calcium oxide 6g, Folium Camelliae sinensis 0.8g, sodium bicarbonate 6g.The number of degrees of Chinese liquor are 50 °, and Folium Camelliae sinensis is green Folium Camelliae sinensis.
The method of the lotion of preparation treatment pink eye disease comprises the following steps:
Step a: take Chinese liquor 94g, calcium oxide 6g, Folium Camelliae sinensis 0.8g, sodium bicarbonate 6g;
Step b: Folium Camelliae sinensis is put into 170mL water, boil, then cooling, obtain tea, standby;
Step c: calcium oxide powder is broken into powder, mixs homogeneously with sodium bicarbonate powder, put into reaction tank;
Steps d: add 23g Chinese liquor, furnishing paste, standing and reacting 2 hours;
Step e: remaining Chinese liquor, all pour in reaction tank, stir, with steam boiler, be heated to, after 100 ℃, naturally cool to 30 ℃, obtain stock solution;
Step f: get tea and the stock solution of step b and step e, mix by the part by weight of 94:6, precipitated
Filter twice, obtains filtrate, treats the lotion of pink eye disease.
Using method: 2-3 time on the one, a 1g.
Embodiment 3
The lotion for the treatment of pink eye disease, is formed by the preparation of raw material of following weight proportioning: Chinese liquor 91g, calcium oxide 5g, Folium Camelliae sinensis 0.5g, sodium bicarbonate 3.5g.The number of degrees of Chinese liquor are 45 °, and Folium Camelliae sinensis is green Folium Camelliae sinensis.
The method of the lotion of preparation treatment pink eye disease comprises the following steps:
Step a: take Chinese liquor 91g, calcium oxide 5g, Folium Camelliae sinensis 0.5g, sodium bicarbonate 3.5g;
Step b: Folium Camelliae sinensis is put into 100mL water, boil, then cooling, obtain tea, standby;
Step c: calcium oxide powder is broken into powder, mixs homogeneously with sodium bicarbonate powder, put into reaction tank; Add 5g Chinese liquor, furnishing paste, standing and reacting 1.5 hours;
Steps d: remaining Chinese liquor, all pour in reaction tank, stir, with steam boiler, be heated to, after 80 ℃, naturally cool to 30 ℃, obtain stock solution;
Step e: get tea and the stock solution of step b and step e, mix by the part by weight of 94:6, sedimentation and filtration twice, obtains filtrate, treats the lotion of pink eye disease.
Using method: 2-3 time on the one, a 1g.
The therapeutic test of 4 pairs of pink eye disease of embodiment
Test group: select suitable patient's 50 examples of the state of an illness, male 23 examples, female's 27 examples, age 25-83 year, (patient's eyes are furious, eyelid is red and swollen, photophobia, and ophthalmic pruritus, burning sensation in eye, shed tears or excessive tear, and eye secretion is many) is in a bad way.The lotion making by embodiment 1, makes spray agent, is sprayed onto around patient's eyes and eye socket, and 3 times on the one, a 1g.
Matched group: select suitable patient's 50 examples of the state of an illness, male 24 examples, female's 26 examples, age 25-80 year, (patient's eyes are furious, eyelid is red and swollen, photophobia, and ophthalmic pruritus, burning sensation in eye, shed tears or excessive tear, and eye secretion is many) is in a bad way.Eye drips 0.25% chloromycetin eyedrops, and every 2 hours once.
After 5 days, observe therapeutic effect.Test group and matched group are compared, and cure rate and relapse rate are in Table 1.
The cure rate of table 1 test group and matched group and relapse rate
| Test group | Matched group | |
| Cure rate | 98% (male 22 examples, female's 27 examples) | 84% (male 22 examples, female's 20 examples) |
| Relapse rate | 2% (female's 1 example) | 8% (male 3 examples, female's 1 example) |
Conclusion: for the patient who is in a bad way, the present invention is more effective than traditional treatment to the therapeutic effect of pink eye disease, the present invention treats the relapse rate of pink eye disease lower than traditional therapy.
The therapeutic test of 5 pairs of pink eye disease of embodiment
Test group: select suitable patient's 70 examples of the state of an illness, male 30 examples, female's 40 examples, age 23-70 year, the state of an illness general (patient's eyes are furious, eyelid is red and swollen, photophobia, ophthalmic pruritus, burning sensation in eye).The lotion making by embodiment 2, makes spray agent, is sprayed onto around patient's eyes and eye socket, and 3 times on the one, a 1g.
Matched group: select suitable patient's 70 examples of the state of an illness, male 38 examples, female's 32 examples, age 25-69 year, the state of an illness general (patient's eyes are furious, eyelid is red and swollen, photophobia, ophthalmic pruritus, burning sensation in eye).Eye drips 0.25% chloromycetin eyedrops, and every 2 hours once.
After 5 days, observe therapeutic effect.Test group and matched group are compared, and cure rate and relapse rate are in Table 2.
The cure rate of table 2 test group and matched group and relapse rate
| Test group | Matched group | |
| Cure rate | 97.1% (male 29 examples, female's 39 examples) | 90.0% (male 33 examples, female's 30 examples) |
| Relapse rate | 1.4% (female's 1 example) | 5.7% (male 3 examples, female's 1 example) |
Conclusion: for the general patient of the state of an illness, the present invention is more effective than traditional treatment to the therapeutic effect of pink eye disease, the present invention treats the relapse rate of pink eye disease lower than traditional therapy.
The therapeutic test of 6 pairs of pink eye disease of embodiment
Test group: select suitable patient's 80 examples of the state of an illness, male 33 examples, female's 47 examples, age 25-83 year, the state of an illness slight (patient's eyes are furious, eyelid is red and swollen, photophobia).The lotion making by embodiment 3, makes spray agent, is sprayed onto around patient's eyes and eye socket, and 2 times on the one, a 1g.
Matched group: select suitable patient's 80 examples of the state of an illness, male 41 examples, female's 39 examples, age 25-80 year, the state of an illness slight (patient's eyes are furious, eyelid is red and swollen, photophobia).Eye drips 0.25% chloromycetin eyedrops, and every 2 hours once.
After 5 days, observe therapeutic effect.Test group and matched group are compared, and cure rate and relapse rate are in Table 3.
The cure rate of table 3 test group and matched group and relapse rate
| Test group | Matched group | |
| Cure rate | 98.8% (male 33 examples, female's 46 examples) | 93.8% (male 40 examples, female's 35 examples) |
| Relapse rate | 0％ | 3.8% (male 2 examples, female's 1 example) |
Conclusion: for the slight patient of the state of an illness, the present invention is more effective than traditional treatment to the therapeutic effect of pink eye disease, the present invention treats the relapse rate of pink eye disease lower than traditional therapy.
In a word, the foregoing is only preferred embodiment of the present invention, all equalizations of doing according to the present patent application the scope of the claims change and modify, and all should belong to the covering scope of patent of the present invention.
Claims (9)
1. a lotion for the treatment of pink eye disease, is characterized in that, is formed: Chinese liquor 88-94%, calcium oxide 4-6%, Folium Camelliae sinensis 0.1-0.8%, sodium bicarbonate 1-6% by the preparation of raw material of following weight proportioning;
Step a: take by weight ratio Chinese liquor, calcium oxide, sodium bicarbonate, Folium Camelliae sinensis, standby;
Step b: Folium Camelliae sinensis is put into the water of 180-220 times of weight, boiled, then cooling, obtain tea, standby;
Step c: calcium oxide powder is broken into powder, mixs homogeneously with sodium bicarbonate, put into reaction tank;
Steps d: add the Chinese liquor of 1%-25% in step a, furnishing paste, standing and reacting 1-2 hour;
Step e: by the Chinese liquor of 75%-99% remaining in step a, all pour in reaction tank, stir, be heated to, after 70-100 ℃, naturally cool to 30 ℃ with steam boiler, obtain stock solution;
Step f: get the stock solution of tea and the step e of step b, mix by the part by weight of 94:6, sedimentation and filtration twice, obtains filtrate, treats the lotion of pink eye disease.
2. a kind of lotion for the treatment of pink eye disease according to claim 1, is characterized in that, wherein the weight proportion of each raw material is: Chinese liquor 90-92%, calcium oxide 4-6%, Folium Camelliae sinensis 0.3-0.6%, sodium bicarbonate 3-4%.
3. a kind of lotion for the treatment of pink eye disease according to claim 1, is characterized in that, wherein the weight proportion of each raw material is: Chinese liquor 91%, calcium oxide 5%, Folium Camelliae sinensis 0.5%, sodium bicarbonate 3.5%.
4. according to a kind of lotion for the treatment of pink eye disease described in claim 1 or 2 or 3, it is characterized in that, the number of degrees of described Chinese liquor are 40-50 °.
5. according to a kind of lotion for the treatment of pink eye disease described in claim 1 or 2 or 3, it is characterized in that, described Folium Camelliae sinensis is green Folium Camelliae sinensis.
6. according to a kind of lotion for the treatment of pink eye disease described in claim 1 or 2 or 3, it is characterized in that, described sodium bicarbonate is Powdered.
7. a kind of lotion for the treatment of pink eye disease according to claim 1, is characterized in that, described lotion is made spray agent.
8. a kind of preparation method for the treatment of the lotion of pink eye disease according to claim 1, comprises the following steps:
Step a: take by weight ratio Chinese liquor, calcium oxide, sodium bicarbonate, Folium Camelliae sinensis, standby;
Step b: Folium Camelliae sinensis is put into the water of 180-220 times of weight, boiled, then cooling, obtain tea, standby;
Step c: calcium oxide powder is broken into powder, mixs homogeneously with sodium bicarbonate, put into reaction tank;
Steps d: add the Chinese liquor of 1%-25% in step a, furnishing paste, standing and reacting 1-2 hour;
Step e: by the Chinese liquor of 75%-99% remaining in step a, all pour in reaction tank, stir, be heated to, after 70-100 ℃, naturally cool to 30 ℃ with steam boiler, obtain stock solution;
Step f: get the stock solution of tea and the step e of step b, mix by the part by weight of 94:6, sedimentation and filtration twice, obtains filtrate, treats the lotion of pink eye disease.
9. a kind of preparation method for the treatment of the lotion of pink eye disease according to claim 8, is characterized in that, the Chinese liquor adding during steps d furnishing paste is 4%-6%, adds the Chinese liquor of 94%-96% remaining in step a in step e.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110424457.1A CN102600300B (en) | 2011-12-17 | 2011-12-17 | Externally-applied liquid medicine for treatment of pinkeye and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110424457.1A CN102600300B (en) | 2011-12-17 | 2011-12-17 | Externally-applied liquid medicine for treatment of pinkeye and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102600300A CN102600300A (en) | 2012-07-25 |
| CN102600300B true CN102600300B (en) | 2014-04-16 |
Family
ID=46518319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110424457.1A Expired - Fee Related CN102600300B (en) | 2011-12-17 | 2011-12-17 | Externally-applied liquid medicine for treatment of pinkeye and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102600300B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100998695A (en) * | 2006-12-28 | 2007-07-18 | 江蕾 | Eye-washing medicine for treating acute conjunctivitis |
| CN101134064A (en) * | 2005-06-04 | 2008-03-05 | 李子春 | Traditional Chinese medicine ophthalmology department antisenescence recovering paste, liquid and pellets |
-
2011
- 2011-12-17 CN CN201110424457.1A patent/CN102600300B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101134064A (en) * | 2005-06-04 | 2008-03-05 | 李子春 | Traditional Chinese medicine ophthalmology department antisenescence recovering paste, liquid and pellets |
| CN100998695A (en) * | 2006-12-28 | 2007-07-18 | 江蕾 | Eye-washing medicine for treating acute conjunctivitis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102600300A (en) | 2012-07-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101279027B (en) | Chinese medicine lotion preparation for curing acute conjunctivitis | |
| CN101590149A (en) | A kind of Chinese medicine composition and preparation method thereof with asthenopia releasing function | |
| CN102362924B (en) | Medicinal composition for treating ophthalmic diseases and preparation method thereof | |
| CN106038612A (en) | Pharmaceutical composition for protecting eyesight as well as preparation method and application thereof | |
| KR100995379B1 (en) | Body care composition and method for preparing the same | |
| CN102166203A (en) | Eye pad for alleviating eye fatigue and preparation method thereof | |
| CN109394829A (en) | A kind of antiallergic and antipruritic composition | |
| CN104523853B (en) | A kind of Glycyrrhiza Oil Compound external preparation and preparation method thereof | |
| CN102600300B (en) | Externally-applied liquid medicine for treatment of pinkeye and preparation method thereof | |
| CN105687086A (en) | Pien Tze Huang pearl cream and production process thereof | |
| CN101601782A (en) | A kind of compound spirit for the treatment of tinea pedis | |
| CN109731040A (en) | A kind of wound remediation composition, preparation method and applications | |
| CN104027651A (en) | Eye drops for treating eye diseases | |
| CN101590132B (en) | Whelk-removing liniment and preparation method thereof | |
| CN101053602B (en) | Medicine for treating oral ulcer and its preparing method | |
| CN105535628A (en) | Medicine for treating amblyopic eye | |
| CN100457167C (en) | Externally used traditional Chinese medicine preparation for treating nasal mucosa erosion and nosebleed and its preparation method | |
| CN105943718B (en) | Agilawood compound traditional Chinese medicine composition as well as preparation method and application thereof | |
| CN104491629A (en) | External traditional Chinese medicinal composition for treating perianal eczema, and preparation method thereof | |
| CN104491562A (en) | Traditional Chinese medicine composition used for treating conjunctivitis | |
| CN115154580B (en) | Traditional Chinese medicine composition for treating corneal pannus, medicine and preparation method of medicine | |
| CN108434203A (en) | A kind of Chinese medicine ointment and its preparation method and application for treating nasal polyp | |
| CN103550357B (en) | A kind of control muscae volitantes collyrium and its production and use | |
| CN104906217A (en) | Traditional Chinese medicine ointment for treating acute catarrhal conjunctivitis and preparation method thereof | |
| CN102327567B (en) | Preparation method for Chinese medicinal lotion for treating engorgement bedsore |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140416 Termination date: 20181217 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |