CN102579694B - Mouthwash for preventing infection after oral surgery - Google Patents
Mouthwash for preventing infection after oral surgery Download PDFInfo
- Publication number
- CN102579694B CN102579694B CN 201210076980 CN201210076980A CN102579694B CN 102579694 B CN102579694 B CN 102579694B CN 201210076980 CN201210076980 CN 201210076980 CN 201210076980 A CN201210076980 A CN 201210076980A CN 102579694 B CN102579694 B CN 102579694B
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- Prior art keywords
- parts
- mouthwash
- collutory
- radix
- oral surgery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 208000015181 infectious disease Diseases 0.000 title claims abstract description 10
- 238000001356 surgical procedure Methods 0.000 title abstract description 5
- 239000002324 mouth wash Substances 0.000 title abstract 5
- 229940051866 mouthwash Drugs 0.000 title abstract 5
- 230000002265 prevention Effects 0.000 claims abstract description 7
- 241000404844 Callicarpa nudiflora Species 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 241000628997 Flos Species 0.000 claims description 5
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 5
- 208000035965 Postoperative Complications Diseases 0.000 abstract description 2
- 206010048038 Wound infection Diseases 0.000 abstract description 2
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- 230000001225 therapeutic effect Effects 0.000 abstract description 2
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 235000005976 Citrus sinensis Nutrition 0.000 abstract 1
- 241000037740 Coptis chinensis Species 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
- 235000013719 Houttuynia cordata Nutrition 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 244000274050 Platycodon grandiflorum Species 0.000 abstract 1
- 235000006753 Platycodon grandiflorum Nutrition 0.000 abstract 1
- 230000007012 clinical effect Effects 0.000 abstract 1
- 230000008693 nausea Effects 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 description 8
- 239000003814 drug Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 5
- 241000222122 Candida albicans Species 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 229940095731 candida albicans Drugs 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002980 postoperative effect Effects 0.000 description 3
- 229920001817 Agar Polymers 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 230000003444 anaesthetic effect Effects 0.000 description 2
- 239000012531 culture fluid Substances 0.000 description 2
- 230000001408 fungistatic effect Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010058046 Post procedural complication Diseases 0.000 description 1
- 206010036410 Postoperative wound infection Diseases 0.000 description 1
- 208000031650 Surgical Wound Infection Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a mouthwash for preventing infection after oral surgery, which is prepared from the following materials according to weight ratio: 4-12 parts of houttuynia cordata, 5-15 parts of costustoot, 3-15 parts of radix paeoniae alba, 3-15 parts of cassia twig, 4-12 parts of callicarpa nudiflora, 6-9 parts of platycodon grandiflorum, 1-5 parts of fructus kochiae, 8-10 parts of safflower carthamus, 7-10 parts of coptis chinensis, 7-9 parts of Seville orange flower and 50-100 parts of water. The mouthwash has an obvious therapeutic effect on nausea which is caused after the oralsurgery, wound infection prevention and other symptoms, a patient dose not have postoperative complications after taking the mouthwash, and the mouthwash has an exact clinical effect.
Description
Technical field
The present invention relates to field of medicaments, specifically, the present invention relates to a kind of collutory for the prevention infection after mouth operation.
Background technology
The infection of wound takes place after the oral surgery easily.Many clinically at present is preventive means to take the Western medicine with antiinflammation.But oral surgery is generally all used anaesthetic, anaesthetic effect hour after operation, and the patient often has symptoms such as nauseating.This situation is not simply to use Western medicine just soluble.Therefore need clinically a kind of not only can prevention infection but also can eliminate the medicine of some ill symptomses of operation back.
Collutory is as a kind of liquid preparation, has easy to use, curative effect advantage rapidly.If can be applied to prevent infection after mouth operation, then can solve some difficult problems that run on coming personally to a great extent.
Summary of the invention
The purpose of this invention is to provide a kind of collutory for the prevention infection after mouth operation.
In order to realize purpose of the present invention, the invention provides a kind of collutory for the prevention infection after mouth operation, it is to be made by following materials by weight: 4～12 parts of Herba Houttuyniae, 5～15 parts of the Radix Aucklandiae, 3～15 parts of the Radix Paeoniae Albas, 3～15 parts of Ramulus Cinnamomi, 4～12 parts of Callicarpa nudiflora, 6～9 parts of Radix Platycodoniss, 1～5 part of the Fructus Kochiae, 8～10 parts on Flos Carthami, 7～10 parts of Rhizoma Coptidis, 7～9 parts of CitrusaurantiumL.Var.amara Engl.s and water 50-100 part.
Preferably, collutory of the present invention is to be made by following materials by weight: 80 parts in 8 parts of Herba Houttuyniae, 10 parts of the Radix Aucklandiae, 7 parts of the Radix Paeoniae Albas, 7 parts of Ramulus Cinnamomi, 8 parts of Callicarpa nudiflora, 7 parts of Radix Platycodoniss, 3 parts of the Fructus Kochiae, 9 parts on Flos Carthami, 8 parts of Rhizoma Coptidis, 8 parts of CitrusaurantiumL.Var.amara Engl.s and water.
Chinese medicine has stronger organic conception.Often can be treated from the characteristics of patient's whole body, and just be not confined to focus itself.For the patient behind the operation on oral cavity, except wanting prevent wound infection, also need to eliminate various post-operative complication, for example feel sick etc.These effects all are that Western medicine is beyond one's reach.Simultaneously collutory is as liquid preparation, and onset is quick, and effect is obvious, take collutory of the present invention after, not only do not see postoperative wound infection, patient's sensation such as more obviously be not sick in the stomach, clinical efficacy is definite.
The specific embodiment
Following examples are used for explanation the present invention, but are not used for limiting the scope of the invention.The preparation of embodiment 1 collutory of the present invention
Get Herba Houttuyniae 80 grams, the Radix Aucklandiae 100 grams, the Radix Paeoniae Alba 70 grams, Ramulus Cinnamomi 70 grams, Callicarpa nudiflora 80 grams, Radix Platycodonis 70 grams, the Fructus Kochiae 30 grams, Flos Carthami 90 grams, Rhizoma Coptidis 80 grams, CitrusaurantiumL.Var.amara Engl. 80 grams and water 800 grams, place in the flask of sealing, heating is 3 hours under 80 ℃ water-bath, filter, collect filtrate, sterilizing namely.
Experimental example 1
1, clinical data
Patient's 40 examples after the oral surgery, male 20 examples, women 20 examples: 21 years old～48 years old age.All patients are all through surgical operation, the postoperative wound suture, and wound length is all less than 5 centimetres.
2, Therapeutic Method
After operation, use the collutory of embodiment 1 preparation, use 20ml to gargle at every turn.Every day 3 times.Used for 1 week continuously.
3, therapeutic outcome
Do not see that to see lump, flicking wound in the postoperative oral cavity it is standard that the swelling sense is not arranged in obvious pain, the oral cavity.By taking collutory of the present invention, find that whole patients all satisfy above-mentioned standard.And the investigation to them learns, patient's postoperative is perception sensation such as significantly feel sick not.
Experimental example 2 external fungistatic effect tests
1. material
1.1 for the examination strain
Staphylococcus aureus (Staphylococcus aureus) ATCC 25923, Candida albicans (Candida albicans) ACTT 12228 is all available from Chinese biological goods calibrating institute.
1.2 culture fluid
Nutrient agar and nutrient broth are all available from BeiJing ZhongKe's space in morning experimental facilities company limited.
1.3 test method
Staphylococcus aureus and Candida albicans are inoculated on the agar plate nutritional solution plane, evenly gather during inoculation.The aseptic circular filter paper sheet of tweezer uses the collutory of preparation among the embodiment 1 that filter paper is squirted, and makes filter paper drop on it when vertically leaving standstill just begin to drip.Filter paper is attached on the culture fluid of inoculated bacteria.Agar plate placed in 37 ℃ the incubator incubation 24 hours.Measure the diameter of antibacterial ring.Measuring 3 times averages.
1.4 result
The average diameter of the antibacterial ring of staphylococcus aureus is 10.23mm, and the average diameter of the antibacterial ring of Candida albicans is 8.43mm, shows that collutory of the present invention has tangible fungistatic effect.
Claims (2)
1. a collutory that is used for the prevention infection after mouth operation is characterized in that it is to be made by following materials by weight: 4～12 parts of Herba Houttuyniae, 5～15 parts of the Radix Aucklandiae, 3～15 parts of the Radix Paeoniae Albas, 3～15 parts of Ramulus Cinnamomi, 4～12 parts of Callicarpa nudiflora, 6～9 parts of Radix Platycodoniss, 1～5 part of the Fructus Kochiae, 8～10 parts on Flos Carthami, 7～10 parts of Rhizoma Coptidis, 7～9 parts of CitrusaurantiumL.Var.amara Engl.s and water 50-100 part.
2. collutory according to claim 1 is characterized in that it is to be made by following materials by weight: 80 parts in 8 parts of Herba Houttuyniae, 10 parts of the Radix Aucklandiae, 7 parts of the Radix Paeoniae Albas, 7 parts of Ramulus Cinnamomi, 8 parts of Callicarpa nudiflora, 7 parts of Radix Platycodoniss, 3 parts of the Fructus Kochiae, 9 parts on Flos Carthami, 8 parts of Rhizoma Coptidis, 8 parts of CitrusaurantiumL.Var.amara Engl.s and water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210076980 CN102579694B (en) | 2012-03-22 | 2012-03-22 | Mouthwash for preventing infection after oral surgery |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210076980 CN102579694B (en) | 2012-03-22 | 2012-03-22 | Mouthwash for preventing infection after oral surgery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102579694A CN102579694A (en) | 2012-07-18 |
| CN102579694B true CN102579694B (en) | 2013-07-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210076980 Active CN102579694B (en) | 2012-03-22 | 2012-03-22 | Mouthwash for preventing infection after oral surgery |
Country Status (1)
| Country | Link |
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| CN (1) | CN102579694B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103656219B (en) * | 2013-12-07 | 2016-02-24 | 蒋云生 | Medicine for the treatment of wound and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN1895291A (en) * | 2006-06-09 | 2007-01-17 | 陈永丽 | Nano-Chinese medicinal biological product and its preparation |
-
2012
- 2012-03-22 CN CN 201210076980 patent/CN102579694B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN1895291A (en) * | 2006-06-09 | 2007-01-17 | 陈永丽 | Nano-Chinese medicinal biological product and its preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102579694A (en) | 2012-07-18 |
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| C14 | Grant of patent or utility model | ||
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Owner name: LIYANG SHANGHUANG HOSPITALS Free format text: FORMER OWNER: ZHU LIANGHUAN Effective date: 20131122 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272100 JINING, SHANDONG PROVINCE TO: 213314 CHANGZHOU, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20131122 Address after: 213314, Huang Zhen Town, Liyang, Jiangsu, Changzhou Patentee after: Liyang Huang Zhen Town Health Center Address before: 272100 Jining Stomatological Hospital, 44 Youth League Road, Shandong, Jining Patentee before: Zhu Lianghuan |