CN102579448A - 预防并减轻应激相关病症严重程度的方法 - Google Patents

预防并减轻应激相关病症严重程度的方法 Download PDF

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Publication number
CN102579448A
CN102579448A CN2011104449533A CN201110444953A CN102579448A CN 102579448 A CN102579448 A CN 102579448A CN 2011104449533 A CN2011104449533 A CN 2011104449533A CN 201110444953 A CN201110444953 A CN 201110444953A CN 102579448 A CN102579448 A CN 102579448A
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Prior art keywords
brimonidine
severity
mice
inventive method
stress
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Pending
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CN2011104449533A
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English (en)
Chinese (zh)
Inventor
D·W·吉尔
S·M·惠特卡普
M·F·布林
J·E·唐奈罗
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Allergan Inc
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Allergan Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33540268&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102579448(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CN102579448A publication Critical patent/CN102579448A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2011104449533A 2003-06-25 2004-06-22 预防并减轻应激相关病症严重程度的方法 Pending CN102579448A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/607,439 US20040266776A1 (en) 2003-06-25 2003-06-25 Methods of preventing and reducing the severity of stress-associated conditions
US10/607,439 2003-06-25

Related Parent Applications (1)

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CNA2004800178422A Division CN1812791A (zh) 2003-06-25 2004-06-22 预防并减轻应激相关病症严重程度的方法

Publications (1)

Publication Number Publication Date
CN102579448A true CN102579448A (zh) 2012-07-18

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CN2011104449533A Pending CN102579448A (zh) 2003-06-25 2004-06-22 预防并减轻应激相关病症严重程度的方法
CNA2004800178422A Pending CN1812791A (zh) 2003-06-25 2004-06-22 预防并减轻应激相关病症严重程度的方法

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Country Link
US (6) US20040266776A1 (enExample)
EP (1) EP1638569B1 (enExample)
JP (2) JP2007524625A (enExample)
KR (1) KR20060023575A (enExample)
CN (2) CN102579448A (enExample)
AT (1) ATE539751T1 (enExample)
AU (2) AU2004253500A1 (enExample)
BR (1) BRPI0411826A (enExample)
CA (1) CA2530487C (enExample)
DK (1) DK1638569T3 (enExample)
ES (1) ES2376878T3 (enExample)
MX (1) MXPA05013900A (enExample)
TW (1) TWI371276B (enExample)
WO (1) WO2005002580A1 (enExample)

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Also Published As

Publication number Publication date
US7977335B2 (en) 2011-07-12
MXPA05013900A (es) 2006-02-24
HK1090282A1 (en) 2006-12-22
AU2004253500A1 (en) 2005-01-13
CN1812791A (zh) 2006-08-02
ATE539751T1 (de) 2012-01-15
US20130217694A1 (en) 2013-08-22
EP1638569B1 (en) 2012-01-04
DK1638569T3 (da) 2012-04-02
AU2010241513B9 (en) 2011-10-20
US20120302574A1 (en) 2012-11-29
TWI371276B (en) 2012-09-01
US20040266776A1 (en) 2004-12-30
AU2010241513A1 (en) 2010-12-09
WO2005002580A1 (en) 2005-01-13
US20080207627A1 (en) 2008-08-28
JP2012092123A (ja) 2012-05-17
CA2530487A1 (en) 2005-01-13
US20130102612A1 (en) 2013-04-25
TW200524611A (en) 2005-08-01
BRPI0411826A (pt) 2006-08-08
KR20060023575A (ko) 2006-03-14
ES2376878T3 (es) 2012-03-20
EP1638569A1 (en) 2006-03-29
AU2010241513B2 (en) 2011-09-22
US20080207628A1 (en) 2008-08-28
CA2530487C (en) 2011-11-01
JP2007524625A (ja) 2007-08-30

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