CN102579306B - Toothpaste containing chrysanthemum extraction solution compound mineral salt - Google Patents

Abstract

The invention discloses toothpaste containing chrysanthemum extraction solution compound mineral salt. Simultaneously, the invention further discloses a preparation method for chrysanthemum extraction solution compound mineral salt constituents and toothpaste. The chrysanthemum extraction solution compound mineral salt constituents comprises chrysanthemum and mineral salt with weight proportion of 0.8-1.2 to 1.8-2.2. The toothpaste containing the chrysanthemum extraction solution compound mineral salt has effects on heat clearing, inflammation diminishment, ozotomia removal and the like, and especially has good alleviation effects on red swollen of gum. Due to the fact that main constituents are natural extractives, the toothpaste is suitable for the old, the young, women and children and has benefit instead of harm for long-term using.

Description

A kind of toothpaste that contains chrysanthemum extraction solution compound mineral salt

Technical field

The invention discloses a kind of toothpaste that contains chrysanthemum extraction solution compound mineral salt, meanwhile, the invention also discloses the preparation method of this chrysanthemum extraction solution compound mineral salt composition and toothpaste.

Background technology

Toothpaste is to be used from cleaning teeth with toothbrush one, and protection oral hygiene, to a kind of daily necessities of human-body safety, has very long history.Along with social progress, various types of toothpaste is come out one after another, and natural drug is applied in toothpaste and solves relevant oral problem as active component, has become market mainstream focus.But up to now, not yet there is a toothpaste Flos Chrysanthemi and mineral salt to be combined to the toothpaste of application.

Flos Chrysanthemi, plantation extensively, drink with a long history, mainly contain Flos Chrysanthemi, milli chrysanthemum, Flos Chrysanthemi, Flos Chrysanthemi, Flos Chrysanthemi, Flos Chrysanthemi, Flos Chrysanthemi and Herba Tagetis Patulae etc., Chrysanthemum morifolium in China's Chinese medicine is the dry capitulum of feverfew Flos Chrysanthemi, and Flos Chrysanthemi is as a kind of common heat-clearing and detoxifying herb, wide material sources, cheap, clinical efficacy is definite, and its extract is applied to daily chemical products, especially having a extensive future in dental products.

Summary of the invention

In order to solve the technical problem existing in prior art, the object of the present invention is to provide a kind of toothpaste that contains chrysanthemum extraction solution compound mineral salt.Meanwhile, another object of the present invention is to provide the method for preparing chrysanthemum extraction solution compound mineral salt composition and toothpaste.

The technical solution adopted in the present invention is as follows:

A kind of chrysanthemum extraction solution compound mineral salt composition, contains weight ratio and is 0.8～1.2: 1.8～2.2 Flos Chrysanthemi and mineral salt.

The preparation method of chrysanthemum extraction solution compound mineral salt composition, comprises the steps:

1., taking is Flos Chrysanthemi by weight proportion: ethanol: mineral salt: pure water=0.8～1.2: 8～12: 1.8～2.2: 8～12 raw material;

2., Flos Chrysanthemi and ethanol are mixed and soaks 36～48h, filter and to obtain Flos Chrysanthemi ethanol filter liquide A and Flos Chrysanthemi filters filtering residue B;

3., Flos Chrysanthemi filtered to filtering residue B mix with mineral salt, add pure water and decoct 2～4 times, each 2h, collects decoction liquor;

4., by 2. Flos Chrysanthemi ethanol filter liquide A and 3. decoction liquor mix homogeneously of step of step, decolouring, the concentrated chrysanthemum salt extracting solution that to obtain.

Preferably, the volumn concentration of described ethanol is 40～95%.

Preferably, 3. to decoct temperature be 70～100 DEG C to described step.

The toothpaste that contains chrysanthemum extraction solution compound mineral salt, contains weight ratio and is 1.5～2.5% chrysanthemum salt extracting solution in lotion of toothpaste total composition, other components can be prepared component according to existing toothpaste and add.

Further, the invention also discloses a kind of component and content of toothpaste, as described below:

The preparation method of the toothpaste that contains chrysanthemum extraction solution compound mineral salt, comprises the steps:

1., sodium lauryl sulfate is dissolved in pure water to formation mixture D 1;

2., Carboxymethyl cellulose sodium is scattered in silicon dioxide to formation mixture D 2;

3., by chrysanthemum salt extracting solution, tertiary sodium phosphate, saccharin sodium and mixture D 1 mix homogeneously, heating 5～10min, form mixture D 3;

4., sorbitol is mixed homogeneously with mixture D 2, heating 5～10min, forms mixture D 4;

5., mixture D 3, D4 are added in emulsifying pot, add spice mix homogeneously, under vacuum, stir 5～10min, make mastic, be filled into multiple tube.

Preferably, described step 3. heating-up temperature be 50～70 DEG C.

Preferably, described step 4. heating-up temperature be 60～70 DEG C.

Physico-chemical analysis shows, contains volatile oil, chrysanthemum glycoside, adenine, aminoacid, choline, stachydrine, berberine, flavonoid, asterin, vitamin in Flos Chrysanthemi, and the materials such as trace element can antipathogen, strengthens capillary resistance; Flavonoid material wherein has been proved to be has very strong scavenging action to free radical, and at antioxidation, and the health care aspect of waiting for a long time is fruitful.From threpsology's angle analysis, the elite of plant is flowers and fruits, contains 17 seed amino acids in Chrysanthemum Petal, and its Glutamic Acid, aspartic acid, proline equal size are higher.

In addition, in Flos Chrysanthemi, be also rich in vitamin and ferrum, zinc, copper, selenium and other trace elements, thereby there is the incomparable effect of general vegetables and fruits.

The toothpaste that the present invention contains chrysanthemum extraction solution compound mineral salt, can play the effects such as heat clearing away, pathogenic fire reducing, antiinflammatory, antihalitosis, has good remission effect especially for red swelling of gingiva.Because main component is natural extract, old and young women and children are all suitable, and life-time service is useful and harmless.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further illustrated, it should be noted that, the various raw materials such as mineral salt are delicatessen food level, or obtain according to prior art preparation.

Embodiment mono-

1, the preparation of chrysanthemum salt extracting solution

Proportioning raw materials

Raw material	Weight
		Flos Chrysanthemi	8g
40% ethanol	90g
		Mineral salt	22g
Pure water	80g

Preparation process is as follows:

1., Flos Chrysanthemi and ethanol are mixed and soaks 48h, filter and to obtain Flos Chrysanthemi ethanol filter liquide A and Flos Chrysanthemi filters filtering residue B;

2., Flos Chrysanthemi filtered to filtering residue B mix with mineral salt, add pure water and decoct 2 times, decocting temperature is 80 DEG C, each 2h, collects decoction liquor;

3., by 1. Flos Chrysanthemi ethanol filter liquide A and 2. decoction liquor mix homogeneously of step of step, decolouring, the concentrated chrysanthemum salt extracting solution that to obtain.

2, the preparation of toothpaste

Each raw material components content following (in 100g, lower same):

Raw material	Weight	Raw material	Weight
				Chrysanthemum salt extracting solution	1.5g	Tertiary sodium phosphate	0.3g
Silicon dioxide	15g	Carboxymethyl cellulose sodium	0.5g
				Sorbitol	62.5g	Saccharin sodium	0.18g
Sodium lauryl sulfate	2.5g	Spice	0.5g
				Pure water	Surplus (supplying 100g)

Preparation process is as follows:

1., sodium lauryl sulfate is dissolved in pure water to formation mixture D 1;

2., Carboxymethyl cellulose sodium is scattered in silicon dioxide to formation mixture D 2;

3., by chrysanthemum salt extracting solution, tertiary sodium phosphate, saccharin sodium and mixture D 1 mix homogeneously, heating 5min, heating-up temperature is 55 DEG C, form mixture D 3;

4., sorbitol is mixed homogeneously with mixture D 2, heating 5min, heating-up temperature is 60 DEG C, forms mixture D 4;

5., mixture D 3, D4 are added in emulsifying pot, add spice mix homogeneously, under vacuum, stir 10min, make mastic, be filled into multiple tube.

Embodiment bis-

1, the preparation of chrysanthemum salt extracting solution

Proportioning raw materials

Raw material	Weight
		Flos Chrysanthemi	17g
95% ethanol	240g
		Mineral salt	38g
Pure water	200g

Step 1. soak time is 45h, and 2. step decocts 2 times, and decocting temperature is 75 DEG C, and other is with embodiment mono-.

2, the preparation of toothpaste

Each raw material components content is as follows:

Raw material	Weight	Raw material	Weight
				Chrysanthemum salt extracting solution	1.7g	Tertiary sodium phosphate	0.5g
Silicon dioxide	18g	Carboxymethyl cellulose sodium	1g
				Sorbitol	50g	Saccharin sodium	0.25g
Sodium lauryl sulfate	2g	Spice	1g
				Pure water	Surplus

3. step heats 9min, and heating-up temperature is 60 DEG C; 4. step heats 6min, and heating-up temperature is 65 DEG C; 5. step stirs 5min, and other is with embodiment mono-.

Embodiment tri-

1, the preparation of chrysanthemum salt extracting solution

Proportioning raw materials

Raw material	Weight
		Flos Chrysanthemi	6g
90% ethanol	40g
		Mineral salt	10g
Pure water	55g

Step 1. soak time is 42h, and 2. step decocts 2 times, and decocting temperature is 70 DEG C, and other is with embodiment mono-.

2, the preparation of toothpaste

Each raw material components content is as follows:

Raw material	Weight	Raw material	Weight
				Chrysanthemum salt extracting solution	1.9g	Tertiary sodium phosphate	0.4g
Silicon dioxide	14g	Carboxymethyl cellulose sodium	1.5g
				Sorbitol	75g	Saccharin sodium	0.2g
Sodium lauryl sulfate	1.5g	Spice	1.5g
				Pure water	Surplus

3. step heats 10min, and heating-up temperature is 50 DEG C; 4. step heats 10min, and heating-up temperature is 68 DEG C; 5. step stirs 8min, and other is with embodiment mono-.

Embodiment tetra-

1, the preparation of chrysanthemum salt extracting solution

Proportioning raw materials

Raw material	Weight
		Flos Chrysanthemi	5.4g
80% ethanol	60g
		Mineral salt	12.6g
Pure water	57g

Step 1. soak time is 40h, and 2. step decocts 4 times, and decocting temperature is 85 DEG C, and other is with embodiment mono-.

2, the preparation of toothpaste

Each raw material components content is as follows:

Raw material	Weight	Raw material	Weight
				Chrysanthemum salt extracting solution	2g	Tertiary sodium phosphate	0.1g
Silicon dioxide	17g	Carboxymethyl cellulose sodium	0.75g
				Sorbitol	55g	Saccharin sodium	0.15g
Sodium lauryl sulfate	1g	Spice	0.85g
				Pure water	Surplus

3. step heats 6min, and heating-up temperature is 65 DEG C; 4. step heats 7min, and heating-up temperature is 63 DEG C; 5. step stirs 9min, and other is with embodiment mono-.

Embodiment five

1, the preparation of chrysanthemum salt extracting solution

Proportioning raw materials

Raw material	Weight
		Flos Chrysanthemi	8g
70% ethanol	88g
		Mineral salt	14.4g
Pure water	72g

Step 1. soak time is 38h, and 2. step decocts 3 times, and decocting temperature is 100 DEG C, and other is with embodiment mono-.

2, the preparation of toothpaste

Each raw material components content is as follows:

Raw material	Weight	Raw material	Weight
				Chrysanthemum salt extracting solution	2.2g	Tertiary sodium phosphate	0.2g
Silicon dioxide	16g	Carboxymethyl cellulose sodium	0.95g
				Sorbitol	65g	Saccharin sodium	0.3g
Sodium lauryl sulfate	1.8g	Spice	1.15g
				Pure water	Surplus

3. step heats 7min, and heating-up temperature is 70 DEG C; 4. step heats 8min, and heating-up temperature is 65 DEG C; 5. step stirs 7min, and other is with embodiment mono-.

Embodiment six

1, the preparation of chrysanthemum salt extracting solution

Proportioning raw materials

Raw material	Weight
		Flos Chrysanthemi	13.2g
60% ethanol	114g
		Mineral salt	24.6g
Pure water	144g

Step 1. soak time is 36h, and 2. step decocts 4 times, and decocting temperature is 90 DEG C, and other is with embodiment mono-.

2, the preparation of toothpaste

Each raw material components content is as follows:

Raw material	Weight	Raw material	Weight
				Chrysanthemum salt extracting solution	2.5g	Tertiary sodium phosphate	0.25g
Silicon dioxide	13g	Carboxymethyl cellulose sodium	1.25g
				Sorbitol	70g	Saccharin sodium	0.1g
Sodium lauryl sulfate	1.6g	Spice	1g
				Pure water	Surplus

3. step heats 8min, and heating-up temperature is 60 DEG C; 4. step heats 9min, and heating-up temperature is 70 DEG C; 5. step stirs 6min, and other is with embodiment mono-.

Comparative example one

Only be with the difference of embodiment mono-, while preparing toothpaste, do not add chrysanthemum salt extracting solution, other component and content are identical.

Clinical trial result

Test method: choose experimenter 90 people with red swelling of gingiva symptom and test, the each half of men and women, the age is from 18～59 years old, 30 years old mean age.Be divided at random 2 groups, the toothpaste (containing chrysanthemum salt extracting solution) that experimental group uses embodiment mono-to prepare, the toothpaste (not containing chrysanthemum salt extracting solution) that matched group uses comparative example one to prepare.Every morning, evening respectively brush teeth once.

Brush teeth before test, first record experimenter's red swelling of gingiva symptom.

Brush teeth test after the 7th day, more unified inspection experimenter's red swelling of gingiva symptom variation.

Criterion: brush teeth after test, experimenter's red swelling of gingiva alleviate or eliminates be effective, otherwise redness increases the weight of or unchanged person be considered as invalid.

Inspection after experimenter uses seven days, result is as follows:

From experimenter's assay, the toothpaste (fragrant grass chrysanthemum salt toothpaste) that the present invention contains chrysanthemum extraction solution compound mineral salt is 86.7% for alleviating red swelling of gingiva symptom effective percentage, can play positive effect after using continuously seven days.

Above content is only to structure of the present invention (composition) example and explanation; affiliated those skilled in the art make various amendments to described specific embodiment or supplement or adopt similar mode to substitute; only otherwise depart from the structure (composition) of invention or surmount this scope as defined in the claims, all should belong to protection scope of the present invention.

Claims (2)

1. contain a toothpaste for chrysanthemum extraction solution compound mineral salt, in lotion of toothpaste total composition, contain weight ratio and be 1.5～2.5% chrysanthemum salt extracting solution, also comprise following component:

The preparation method of described chrysanthemum salt extracting solution is:

1., taking is Flos Chrysanthemi by weight proportion: ethanol: mineral salt: the raw material of pure water=0.8～1.2:8～12:1.8～2.2:8～12;

2., Flos Chrysanthemi and ethanol are mixed and soaks 36～48h, filter and to obtain Flos Chrysanthemi ethanol filter liquide A and Flos Chrysanthemi filters filtering residue B, the volumn concentration of described ethanol is 40～95%;

3., Flos Chrysanthemi filtered to filtering residue B mix with mineral salt, add 70～100 DEG C of pure water and decoct 2～4 times, each 2h, collects decoction liquor;

4., by 2. Flos Chrysanthemi ethanol filter liquide A and 3. decoction liquor mix homogeneously of step of step, decolouring, the concentrated chrysanthemum salt extracting solution that to obtain.

2. the method for the preparation toothpaste that contains chrysanthemum extraction solution compound mineral salt claimed in claim 1, is characterized in that, comprises the steps:

1., sodium lauryl sulfate is dissolved in pure water to formation mixture D 1;

2., Carboxymethyl cellulose sodium is scattered in silicon dioxide to formation mixture D 2;

3., by chrysanthemum salt extracting solution, tertiary sodium phosphate, saccharin sodium and mixture D 1 mix homogeneously, 50～70 DEG C heating 5～10min, form mixture D 3;

4., sorbitol is mixed homogeneously with mixture D 2,60～70 DEG C of heating 5～10min, form mixture D 4;

5., mixture D 3, D4 are added in emulsifying pot, add spice mix homogeneously, under vacuum, stir 5～10min, make mastic, be filled into multiple tube.