CN102576498A - 用于评估剂型在胃肠道中的分解的方法、设备和计算机程序产品 - Google Patents
用于评估剂型在胃肠道中的分解的方法、设备和计算机程序产品 Download PDFInfo
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- CN102576498A CN102576498A CN201080045287XA CN201080045287A CN102576498A CN 102576498 A CN102576498 A CN 102576498A CN 201080045287X A CN201080045287X A CN 201080045287XA CN 201080045287 A CN201080045287 A CN 201080045287A CN 102576498 A CN102576498 A CN 102576498A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/06—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for physics
- G09B23/08—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for physics for statics or dynamics
- G09B23/12—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for physics for statics or dynamics of liquids or gases
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/30—Anatomical models
- G09B23/303—Anatomical models specially adapted to simulate circulation of bodily fluids
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/30—Anatomical models
- G09B23/32—Anatomical models with moving parts
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
- G01N2013/006—Dissolution of tablets or the like
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- Medicinal Chemistry (AREA)
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- Mathematical Optimization (AREA)
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- Pure & Applied Mathematics (AREA)
- Educational Administration (AREA)
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- General Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
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Abstract
Description
Claims (14)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09167516A EP2284821A1 (en) | 2009-08-07 | 2009-08-07 | Method, device and computer program product for assessing the disintegration of a dosage form in the gastrointestinal tract |
EP09167516.5 | 2009-08-07 | ||
PCT/NL2010/050500 WO2011016726A1 (en) | 2009-08-07 | 2010-08-06 | Method, device and computer program product for assessing the disintegration of a dosage form in the gastrointestinal tract |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102576498A true CN102576498A (zh) | 2012-07-11 |
CN102576498B CN102576498B (zh) | 2016-07-06 |
Family
ID=41510924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201080045287.XA Active CN102576498B (zh) | 2009-08-07 | 2010-08-06 | 用于评估剂型在胃肠道中的分解的方法和设备 |
Country Status (9)
Country | Link |
---|---|
US (1) | US9575044B2 (zh) |
EP (2) | EP2284821A1 (zh) |
JP (1) | JP5802207B2 (zh) |
CN (1) | CN102576498B (zh) |
DK (1) | DK2462578T3 (zh) |
ES (1) | ES2665891T3 (zh) |
PL (1) | PL2462578T3 (zh) |
PT (1) | PT2462578T (zh) |
WO (1) | WO2011016726A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108613766A (zh) * | 2018-02-07 | 2018-10-02 | 浙江工商大学 | 一种人工胃体内部挤压力的测定方法 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2529826A1 (en) | 2011-05-31 | 2012-12-05 | Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO | Membrane filtration system comprising a deformable side wall |
JP6168585B2 (ja) * | 2013-01-25 | 2017-07-26 | 国立研究開発法人農業・食品産業技術総合研究機構 | 胃モデル装置 |
EP2884480A1 (en) * | 2013-12-12 | 2015-06-17 | Sandoz Ag | Apparatus for simulating the function of human stomach and/or human intestine |
KR101975286B1 (ko) * | 2014-08-06 | 2019-05-07 | 헥살 아게 | 필름-형상의 약학적 투여 형태의 분해 시간을 확인하기 위한 방법 및 디바이스 |
EP3412762A1 (en) * | 2017-06-06 | 2018-12-12 | ProDigest BVBA | Gastrointestinal tract simulation system, compartments therefor, and method |
CN108682252B (zh) * | 2018-06-11 | 2020-07-03 | 江南大学 | 一种基于连杆运动的食物吞咽模拟装置 |
CN114295792B (zh) * | 2021-12-28 | 2024-05-10 | 纬壹生物医药研究院(南京)有限公司 | 一种崩解仪 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994009895A1 (en) * | 1992-11-02 | 1994-05-11 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Reactor system |
RU2200979C2 (ru) * | 2000-11-02 | 2003-03-20 | Бубнов Валерий Георгиевич | Медицинский робот-тренажер для обучения манипуляционной технике |
US20030073061A1 (en) * | 2001-10-17 | 2003-04-17 | Toomey Timothy Daniel | Breast lump detection training model with feedback |
WO2006052742A2 (en) * | 2004-11-05 | 2006-05-18 | Smithkline Beecham Corporation | Pharmaceutical analysis apparatus and method |
WO2007010238A1 (en) * | 2005-07-18 | 2007-01-25 | Plant Bioscience Limited | Apparatus, system and method |
FR2923065A1 (fr) * | 2007-10-30 | 2009-05-01 | Univ D Auvergne Clermont 1 Eta | Dispositif de simulation d'un estomac d'un mammifere monogastrique ou d'un etre humain |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3330368A (en) * | 1965-06-07 | 1967-07-11 | Baran Paul | Peristaltic gopher |
US4247298A (en) * | 1979-03-29 | 1981-01-27 | The Regents Of The University Of Minnesota | Drug dissolution with a cascade barrier bed |
AU7533494A (en) * | 1993-08-06 | 1995-02-28 | Ciba-Geigy Ag | Apparatus for simulating the effect of the living organism on the change in shape, the disintegration and dissolution behaviour and the active-ingredient release of a pharmaceutical dosage form |
US5483994A (en) * | 1995-02-01 | 1996-01-16 | Honeywell, Inc. | Pressure transducer with media isolation and negative pressure measuring capability |
US6022733A (en) * | 1997-12-02 | 2000-02-08 | Tam; Yun K. | Simulated biological dissolution and absorption system |
DE60212421T2 (de) | 2001-10-11 | 2006-12-28 | Elan Pharma International Ltd. | Vorrichtung und verfahren zur gleichzeitigen beobachtung der auflösung und des äusseren erscheinungsbildes von arzneimitteln in fester darreichungsform |
CN103509776B (zh) | 2003-06-19 | 2016-10-12 | 诺维信公司 | 蛋白酶 |
WO2005011493A1 (en) | 2003-08-04 | 2005-02-10 | Ditens A/S | Apparatus for detecting axial force in the digestive system |
WO2005095950A1 (en) * | 2004-03-30 | 2005-10-13 | Pfizer Products Inc. | Method and device for evaluation of pharmaceutical compositions |
US7331251B2 (en) * | 2005-06-22 | 2008-02-19 | Idaho State University | Dissolution testing of solid dosage forms intended to be administered in the oral cavity |
US7811297B2 (en) * | 2005-12-10 | 2010-10-12 | Teledyne Scientific & Imaging, Llc | Actuable structures and methods of fabrication and use |
US20090064768A1 (en) | 2007-03-13 | 2009-03-12 | Emad Alkhawam | Devices for Determining the Release Profile of Macromolecules and Methods of Using the Same |
EP2150810A4 (en) | 2007-05-04 | 2013-11-13 | Glaxosmithkline Llc | APPARATUS AND METHOD FOR PHARMACEUTICAL ANALYSIS |
US20090240442A1 (en) * | 2007-06-29 | 2009-09-24 | William Zeng | Method of manufacturing and testing solid dosage products, and apparatus for the testing |
US20100262381A1 (en) * | 2007-06-29 | 2010-10-14 | Zeng William B | Method of manufacturing and testing solid dosage products and apparatus for the testing |
ES2672201T3 (es) * | 2008-07-16 | 2018-06-13 | Children's Medical Center Corporation | Dispositivo de imitación de órganos con microcanales y métodos de uso |
-
2009
- 2009-08-07 EP EP09167516A patent/EP2284821A1/en not_active Withdrawn
-
2010
- 2010-08-06 ES ES10742608.2T patent/ES2665891T3/es active Active
- 2010-08-06 DK DK10742608.2T patent/DK2462578T3/en active
- 2010-08-06 PT PT107426082T patent/PT2462578T/pt unknown
- 2010-08-06 US US13/389,304 patent/US9575044B2/en active Active
- 2010-08-06 JP JP2012523580A patent/JP5802207B2/ja active Active
- 2010-08-06 WO PCT/NL2010/050500 patent/WO2011016726A1/en active Application Filing
- 2010-08-06 PL PL10742608T patent/PL2462578T3/pl unknown
- 2010-08-06 CN CN201080045287.XA patent/CN102576498B/zh active Active
- 2010-08-06 EP EP10742608.2A patent/EP2462578B1/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994009895A1 (en) * | 1992-11-02 | 1994-05-11 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Reactor system |
RU2200979C2 (ru) * | 2000-11-02 | 2003-03-20 | Бубнов Валерий Георгиевич | Медицинский робот-тренажер для обучения манипуляционной технике |
US20030073061A1 (en) * | 2001-10-17 | 2003-04-17 | Toomey Timothy Daniel | Breast lump detection training model with feedback |
WO2006052742A2 (en) * | 2004-11-05 | 2006-05-18 | Smithkline Beecham Corporation | Pharmaceutical analysis apparatus and method |
WO2006052742A3 (en) * | 2004-11-05 | 2006-09-14 | Smithkline Beecham Corp | Pharmaceutical analysis apparatus and method |
CN101087594A (zh) * | 2004-11-05 | 2007-12-12 | 史密丝克莱恩比彻姆公司 | 药物分析装置及方法 |
WO2007010238A1 (en) * | 2005-07-18 | 2007-01-25 | Plant Bioscience Limited | Apparatus, system and method |
FR2923065A1 (fr) * | 2007-10-30 | 2009-05-01 | Univ D Auvergne Clermont 1 Eta | Dispositif de simulation d'un estomac d'un mammifere monogastrique ou d'un etre humain |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108613766A (zh) * | 2018-02-07 | 2018-10-02 | 浙江工商大学 | 一种人工胃体内部挤压力的测定方法 |
Also Published As
Publication number | Publication date |
---|---|
US9575044B2 (en) | 2017-02-21 |
WO2011016726A1 (en) | 2011-02-10 |
DK2462578T3 (en) | 2018-04-30 |
EP2462578B1 (en) | 2018-01-17 |
PT2462578T (pt) | 2018-04-20 |
ES2665891T3 (es) | 2018-04-30 |
CN102576498B (zh) | 2016-07-06 |
US20120279324A1 (en) | 2012-11-08 |
JP5802207B2 (ja) | 2015-10-28 |
JP2013501947A (ja) | 2013-01-17 |
EP2462578A1 (en) | 2012-06-13 |
EP2284821A1 (en) | 2011-02-16 |
PL2462578T3 (pl) | 2018-07-31 |
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Effective date of registration: 20160719 Address after: Holland zest Patentee after: Tres Colin Address before: Delft Patentee before: The Netherlands Organization For Applied Scientific Research |
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Effective date of registration: 20230509 Address after: Delft Patentee after: Tim Holdings Ltd. Address before: Holland zest Patentee before: Tres Colin |