CN102552795A - Drug capable of increasing gastric motility and treating chronic gastritis and preparation method thereof - Google Patents
Drug capable of increasing gastric motility and treating chronic gastritis and preparation method thereof Download PDFInfo
- Publication number
- CN102552795A CN102552795A CN2012100617996A CN201210061799A CN102552795A CN 102552795 A CN102552795 A CN 102552795A CN 2012100617996 A CN2012100617996 A CN 2012100617996A CN 201210061799 A CN201210061799 A CN 201210061799A CN 102552795 A CN102552795 A CN 102552795A
- Authority
- CN
- China
- Prior art keywords
- preparation
- drug
- rhizoma
- fructus
- parched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a preparation method of traditional Chinese medicine, in particular to a drug capable of increasing gastric motility and treating chronic gastritis and a preparation method thereof. The drug is prepared via mixing drug residues, licorice, poria cocos, fructus evodiae, grifola and rhizoma pinelliae preparata, adding water of five times, soaking for 60 minutes, extracting for 5 hours in heat reflux, filtering to prepare 1000 pieces and then coating icing. The losses of effective ingredients of the drug prepared by the preparation method are reduced. Compared with the traditional process, the yield is increased. Moreover, the drug can be rapidly absorbed in the human body. The effective ingredients are not decomposed during the preparation process, and thus the bioavailability of the drug is improved. Therefore, the preparation method has obvious advantages than the original method. Compared with the product prepared in the original process, the ratio of cream extraction is increased by 3 percent, and the bioavailability can be increased by 13 percent. Therefore, the effects are obvious after process innovation, and the efficacy of the product is improved greatly.
Description
Technical field
The present invention relates to a kind of Chinese medicinal preparation method, specifically is a kind of medicine and method for preparing that can increase gastric motility, treatment chronic gastritis.
Background technology
In prior art, the treatment dyspepsia, fall full noisy, the vomiting distension, borborygmus are rushed down down, be good for the stomach with in, the medicine that pleasantization stagnates---stomach found health sheet (drug standard is numbered WS3-B-1979-95), writing out a prescription is: Herba Pogostemonis 75g; Fructus Hordei Germinatus (stir-fry) 75g; Poria 75g; Massa Medicata Fermentata (parched with bran) 75g; Rhizoma Atractylodis 60g; Cortex Magnoliae Officinalis (stir-frying with ginger juice) 60g; Rhizoma Atractylodis Macrocephalae 60g; Radix Aucklandiae 45g; Rhizoma Alismatis 45g; Polyporus 45g; Pericarpium Citri Reticulatae 45g; Rhizoma Pinelliae 45g; Fructus Amomi Rotundus 30g; Radix Glycyrrhizae 30g; Radix Ginseng 30g; Fructus Evodiae (system) 30g.Function cures mainly: be good for the stomach with in, pleasantization stagnates.Be used for dyspepsia, it is noisy to fall to satisfy, the vomiting distension, and borborygmus are rushed down down.Usage and dosage: oral one time 4,2 times on the one.Method for preparing is: above ten Six-elements, and Radix Ginseng, Rhizoma Alismatis, Massa Medicata Fermentata are ground into fine powder; After Herba Pogostemonis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus extract volatile oil, medicinal residues again with Radix Glycyrrhizae, Poria, Fructus Evodiae, Polyporus, Rhizoma Pinelliae decocte with water secondary, 3 hours for the first time, 2 hours for the second time, filter merging filtrate; Percolation (appendix IO of Pharmacopoeia of the People's Republic of China version in 2005) under Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Rhizoma Atractylodis, the photograph fluid extract item carries out percolation with 60% ethanol as solvent, collects the liquid of filtering; Merge with above-mentioned filtrating, concentrating under reduced pressure becomes thick paste, malt fever water logging secondary; Each 2 hours; Filter, merging filtrate, concentrating under reduced pressure become thick paste to merge above-mentioned thick paste; Add fine powder and right amount of auxiliary materials such as Radix Ginseng, mixing is processed granule, and dry below 60 ℃, spray adds volatile oil such as Herba Pogostemonis, Pericarpium Citri Reticulatae, and mixing is pressed into 1000, and sugar coating promptly gets.Its shortcoming is that the product paste-forming rate that this technology obtains does, a recipe quantity need add adjuvant and can reach regulatory specifications, and the medicine of processing absorbs slower in human body; And on this method for preparing the production time long, work efficiency is low, technological temperature is too high; Its active ingredient is prone to be destroyed, and causes curative effect to reduce.
Summary of the invention
The objective of the invention is provides a kind of technological effect the better a kind of medicine and method for preparing that can increase gastric motility, treatment chronic gastritis to above-mentioned deficiency.
Summary of the invention
Technical solution of the present invention is: a kind of method for preparing that can increase gastric motility, treatment chronic gastritis medicine may further comprise the steps:
(1) raw material: Herba Pogostemonis 75g; Fructus Hordei Germinatus (parched) 75g; Poria 75g; Parched with bran Massa Medicata Fermentata 75g; Rhizoma Atractylodis 60g; Stir-frying with ginger juice Cortex Magnoliae Officinalis 60g; Rhizoma Atractylodis Macrocephalae 60g; Radix Aucklandiae 45g; Rhizoma Alismatis 45g; Polyporus 45g; Pericarpium Citri Reticulatae 45g; Rhizoma Pinelliae 45g; Fructus Amomi Rotundus 30g; Radix Glycyrrhizae 30g; Radix Ginseng 30g; Fructus Evodiae (processed) 30g;
(2) method for making: above ten Six-elements, Radix Ginseng, Rhizoma Alismatis, Massa Medicata Fermentata are ground into fine powder; After Herba Pogostemonis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus extracted volatile oil, medicinal residues added 5 times of water gagings with Radix Glycyrrhizae, Poria, Fructus Evodiae (processed), Polyporus, Rhizoma Pinelliae again, soaked 60 minutes, and heating and refluxing extraction 5 hours filters; Stir-frying with ginger juice Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Rhizoma Atractylodis carry out percolation with 60% ethanol as solvent, collect the liquid of filtering, and merge concentrating under reduced pressure relative density 1.30～1.35 thick pastes with above-mentioned filtrating; 80 ℃ of Fructus Hordei Germinatus (parched) hot water soak secondary, and each 2 hours, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.35; Merge above-mentioned thick paste; Add Radix Ginseng, Rhizoma Alismatis, parched with bran Massa Medicata Fermentata fine powder and adjuvant, mixing is processed granule, and dry below 60 ℃, spray adds Herba Pogostemonis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus volatile oil, and mixing is pressed into 1000, and sugar coating promptly gets.
Advantage of the present invention is: 1, the effective ingredient processed of the present invention decrease vow few; Improved yield than traditional handicraft; And medicine infiltration rate very fast (disintegration time shortening) in human body; Active ingredient is not decomposed in the middle of the preparation process, thereby has improved bioavailability of medicament, has remarkable advantages than former method.2, two of the present invention and former technology kinds of its paste-forming rates of the product that technology obtains differ 3%, and bioavailability can improve 13%, this shows process innovation optimization after effect obviously show the curative effect that has improved product greatly.
To combine embodiment that embodiment of the present invention is described in further detail below.
The specific embodiment
A kind of medicine and method for preparing that can increase gastric motility, treatment chronic gastritis may further comprise the steps:
(1) raw material: Herba Pogostemonis 75g; Fructus Hordei Germinatus (stir-fry) 75g; Poria 75g; Massa Medicata Fermentata (parched with bran) 75g; Rhizoma Atractylodis 60g; Cortex Magnoliae Officinalis (stir-frying with ginger juice) 60g; Rhizoma Atractylodis Macrocephalae 60g; Radix Aucklandiae 45g; Rhizoma Alismatis 45g; Polyporus 45g; Pericarpium Citri Reticulatae 45g; Rhizoma Pinelliae 45g; Fructus Amomi Rotundus 30g; Radix Glycyrrhizae 30g; Radix Ginseng 30g; Fructus Evodiae (system) 30g.
(2) method for preparing is: above ten Six-elements, and Radix Ginseng, Rhizoma Alismatis, Massa Medicata Fermentata are ground into fine powder; After Herba Pogostemonis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus extracted volatile oil, medicinal residues added 5 times of water gagings with Radix Glycyrrhizae, Poria, Fructus Evodiae, Polyporus, Rhizoma Pinelliae again, soaked 60 minutes, and heating and refluxing extraction 5 hours filters; Percolation (appendix IO of Pharmacopoeia of the People's Republic of China version in 2010) under Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Rhizoma Atractylodis, the photograph fluid extract item; Carry out percolation with 60% ethanol as solvent; The collection liquid of filtering merges concentrating under reduced pressure relative density 1.30～1.35 thick pastes with above-mentioned filtrating; Fructus Hordei Germinatus hot water (80 ℃) soaks secondary, and each 2 hours, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.35; Merge above-mentioned thick paste; Add fine powder and right amount of auxiliary materials such as Radix Ginseng, mixing is processed granule, and dry below 60 ℃, spray adds volatile oil such as Herba Pogostemonis, Pericarpium Citri Reticulatae, and mixing is pressed into 1000, and sugar coating promptly gets.
The process choice Orthogonal experiment results is:
The factor level table
Orthogonal Experiment and Design table and result
Select optimum experimental condition to be by above-mentioned result of the test: 5 hours extraction times, thickening temperature is 80 ℃.
Claims (1)
1. method for preparing that can increase gastric motility, treatment chronic gastritis medicine may further comprise the steps:
(1) raw material: Herba Pogostemonis 75g; Fructus Hordei Germinatus (parched) 75g; Poria 75g; Parched with bran Massa Medicata Fermentata 75g; Rhizoma Atractylodis 60g; Stir-frying with ginger juice Cortex Magnoliae Officinalis 60g; Rhizoma Atractylodis Macrocephalae 60g; Radix Aucklandiae 45g; Rhizoma Alismatis 45g; Polyporus 45g; Pericarpium Citri Reticulatae 45g; Rhizoma Pinelliae 45g; Fructus Amomi Rotundus 30g; Radix Glycyrrhizae 30g; Radix Ginseng 30g; Fructus Evodiae (processed) 30g;
(2) method for making: above ten Six-elements, Radix Ginseng, Rhizoma Alismatis, Massa Medicata Fermentata are ground into fine powder; After Herba Pogostemonis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus extracted volatile oil, medicinal residues added 5 times of water gagings with Radix Glycyrrhizae, Poria, Fructus Evodiae (processed), Polyporus, Rhizoma Pinelliae again, soaked 60 minutes, and heating and refluxing extraction 5 hours filters; Stir-frying with ginger juice Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Rhizoma Atractylodis carry out percolation with 60% ethanol as solvent, collect the liquid of filtering, and merge concentrating under reduced pressure relative density 1.30～1.35 thick pastes with above-mentioned filtrating; 80 ℃ of Fructus Hordei Germinatus (parched) hot water soak secondary, and each 2 hours, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.35; Merge above-mentioned thick paste; Add Radix Ginseng, Rhizoma Alismatis, parched with bran Massa Medicata Fermentata fine powder and adjuvant, mixing is processed granule, and dry below 60 ℃, spray adds Herba Pogostemonis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus volatile oil, and mixing is pressed into 1000, and sugar coating promptly gets.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100617996A CN102552795A (en) | 2012-03-09 | 2012-03-09 | Drug capable of increasing gastric motility and treating chronic gastritis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100617996A CN102552795A (en) | 2012-03-09 | 2012-03-09 | Drug capable of increasing gastric motility and treating chronic gastritis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102552795A true CN102552795A (en) | 2012-07-11 |
Family
ID=46400249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100617996A Pending CN102552795A (en) | 2012-03-09 | 2012-03-09 | Drug capable of increasing gastric motility and treating chronic gastritis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102552795A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103272169A (en) * | 2013-06-26 | 2013-09-04 | 中国科学院西北高原生物研究所 | Application of rhodiola rosea compound composite in treating erosive gastritis |
| CN105435099A (en) * | 2015-12-11 | 2016-03-30 | 王平平 | Traditional Chinese medicine for treating superficial gastritis caused by damp heat in spleen and stomach |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1733181A (en) * | 2005-08-01 | 2006-02-15 | 颜怀玮 | Medicine, food used article for preventing and curing chronic gastroenteritis and method for producing the same |
| CN101766732A (en) * | 2008-12-31 | 2010-07-07 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Chinese medicine composite for treating gastrointestinal diseases and preparation method thereof |
| CN102284041A (en) * | 2010-06-17 | 2011-12-21 | 苏州知微堂生物科技有限公司 | Preparation technology and production method of integrated novel Pingwei powder dosage form |
-
2012
- 2012-03-09 CN CN2012100617996A patent/CN102552795A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1733181A (en) * | 2005-08-01 | 2006-02-15 | 颜怀玮 | Medicine, food used article for preventing and curing chronic gastroenteritis and method for producing the same |
| CN101766732A (en) * | 2008-12-31 | 2010-07-07 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Chinese medicine composite for treating gastrointestinal diseases and preparation method thereof |
| CN102284041A (en) * | 2010-06-17 | 2011-12-21 | 苏州知微堂生物科技有限公司 | Preparation technology and production method of integrated novel Pingwei powder dosage form |
Non-Patent Citations (2)
| Title |
|---|
| 中华人民共和国卫生部药典委员会: "《中华人民共和国卫生部药品标准》", 31 December 1995 * |
| 董方言等: "《现代实用中药新剂型新技术》", 30 April 2004 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103272169A (en) * | 2013-06-26 | 2013-09-04 | 中国科学院西北高原生物研究所 | Application of rhodiola rosea compound composite in treating erosive gastritis |
| CN103272169B (en) * | 2013-06-26 | 2014-08-27 | 中国科学院西北高原生物研究所 | Application of rhodiola rosea compound composite in treating erosive gastritis |
| CN105435099A (en) * | 2015-12-11 | 2016-03-30 | 王平平 | Traditional Chinese medicine for treating superficial gastritis caused by damp heat in spleen and stomach |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102512587B (en) | Decoction for treating viral myocarditis | |
| CN105265672B (en) | Production method of walnut diaphragma juglandis tea | |
| CN105125689B (en) | A kind of lavipeditum powder containing the FUKE QIANJIN PIAN dregs of a decoction and preparation method thereof | |
| CN108029821A (en) | Bark of eucommia solid health-care tea and preparation method thereof | |
| CN102552837A (en) | Preparation method of xiaoqinglong mixture | |
| CN103417612A (en) | Chinese herbal medicine processed radix puerariae decoction pieces and preparation method thereof | |
| CN102552795A (en) | Drug capable of increasing gastric motility and treating chronic gastritis and preparation method thereof | |
| CN103849532A (en) | Reinvigoration and healthcare medicinal wine | |
| CN103566165A (en) | Process of exocarpium citri grandis tablets | |
| CN105395893A (en) | Oral solution for clearing heat from throat and preparation method thereof | |
| CN102727789B (en) | Chinese herbal medicine composition for treating lumbar intervertebral disc herniation | |
| CN106581345A (en) | Stomach disease treating medicine and production method thereof | |
| CN105586224A (en) | Xiaoyao black soybean wine, honey wine black soybeans and preparation methods thereof | |
| CN104587370A (en) | Traditional Chinese medicinal composition for treating liver cirrhosis | |
| CN111905075A (en) | Traditional Chinese medicine preparation for warming middle-jiao and harmonizing stomach and preparation method thereof | |
| CN103610799A (en) | Preparation process of immature bitter orange, longstamen onion bulb and cassia twig decoction | |
| CN1772275A (en) | Medicine for treating diseases of intestine, spleen and kidney and its making process | |
| CN100337680C (en) | Compsn. of edinebriating capsule and preparing method | |
| CN107007802B (en) | Compound Chinese medicine preparation for treating leukemia caused by deficiency of both yin and yang and its preparing process | |
| CN107029110B (en) | Traditional Chinese medicine compound preparation for treating anemia caused by spleen deficiency and blood deficiency and preparation method | |
| CN102078423B (en) | External Chinese herbal medicine preparation for treating hyperosteogeny | |
| CN106620017A (en) | Poria cocos and bamboo fungus oral solution | |
| CN107029111B (en) | Traditional Chinese medicine compound preparation for treating leukemia caused by vital qi deficiency and pathogenic factor latent and preparation method thereof | |
| CN103656570A (en) | Chinese medicine liquid for treating stomach tumor and preparation method thereof | |
| CN107007790B (en) | Chinese herbal compound preparation for treating leukemia caused by qi stagnation and phlegm accumulation and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20120711 |