CN102552590A - 一种治疗小儿腹泻的药剂 - Google Patents
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- CN102552590A CN102552590A CN2011103666557A CN201110366655A CN102552590A CN 102552590 A CN102552590 A CN 102552590A CN 2011103666557 A CN2011103666557 A CN 2011103666557A CN 201110366655 A CN201110366655 A CN 201110366655A CN 102552590 A CN102552590 A CN 102552590A
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Abstract
本发明涉及一种治疗小儿腹泻的药剂，它是由下列原料药制成：天南星、石菖蒲、苦栋子、葛根、黄芩、木贼草、白芥子、冰片、吴茱萸、陈皮、蛇床子和枯矾。本发明所述的药剂的组方合理，疗效明确，可有效地治疗小儿腹泻。
Description
技术领域
本发明涉及医药领域，具体地说，涉及一种治疗小儿腹泻的药剂。
背景技术
小儿秋季腹泻多为轮状病毒引起，好发于3岁以下的婴幼儿，由于小儿患病时多伴有恶心、呕吐、纳差、腹胀等消化适症状，使得口服用药难以治疗。
因此，对于新的治疗小儿腹泻的药剂的寻找从未停止。
发明内容
本发明的目的是提供一种治疗小儿腹泻的药剂。
为了实现本发明的目的，本发明提供一种治疗小儿腹泻的药剂，它是由下列原料药按重量份计制成的：
优选地，它是由下列原料药按重量份计制成的：
优选地，所述药剂为片剂、分散片、贴剂、胶囊剂或硬胶囊剂。
本发明所述的药剂的组方合理，疗效明确，可有效地治疗小儿腹泻。
具体实施方式
以下通过具体实施方式的描述对本发明作进一步说明，但这并非是对本发明的限制，本领域技术人员根据本发明的基本思想，可以做出各种修改或改进，但是只要不脱离本发明的基本思想，均在本发明的范围之内。
实施例1本发明贴剂的制备
取天南星15克、石菖蒲30克、苦栋子15克、葛根10克、黄芩15克、木贼草45克、白芥子30克、冰片10克、吴茱萸10克、陈皮15克、蛇床子50克和枯矾30克，加入20升水在40℃浸泡40分钟。之后，在80℃加热两小时，过滤。使滤液在减压真空干燥至干，过80目筛。取硬脂酸甘油酯80克，加热融化，待温度降至45-50℃时加入上述过筛之后的粉末，搅拌均匀，注入模具中，冷却成型，脱模，制成0.5g圆形药片，附着于医用无纺胶布中间，包装即得。
实验例
诊断标准
西医诊断标准参照《小儿腹泻病学》第一版(方鹤松.小儿腹泻病学[M].北京：人民卫生出版社，2009.480-487.)制定：(1)临床表现：多见于6个月至2岁的婴幼儿；秋冬季多发；粪便稀薄，呈蛋花汤样或水样，每日数次至20余次；常伴发热、呕吐、腹胀和肠鸣(2)实验室检查：便常规多无异常或可看到少量白细胞，粪便检测轮状病毒抗原阳性；
中医诊断标准和辨证分型根据《中医儿科学》(汪受传.中医儿科学[M].2版.北京：中国医药出版社，2007.102-107.)制定：(1)湿热泻：泻如水样，每日数次或数十次，色褐而臭，可有粘液，腹部时感疼痛，食欲不振，或伴泛恶，发热或不发热，口渴，肛门灼热，小便短赤，舌苔黄腻(2)寒湿泻：人便每日数次或十数次，色较淡，可伴有少量粘液，臭气不甚，肠鸣腹痛，或兼恶寒发热，不渴或渴不欲饮，舌苔自腻。
符合上述西医、中医诊断标准，治疗期间未使用其他治疗药物。
选取50例腹泻患儿，男25例，女25例；年龄2个月-5岁，平均年龄3.8岁。
选取实施例1中制备的贴剂进行治疗。在患儿睡觉前使用。使用，用温水清洗患儿的肚脐，将实施例1中制备的贴剂贴于患儿的肚脐上。第二天醒后，将贴剂取下。反复操作3天为一个疗程。
治疗标准如下
疾病疗效判定标准参照《中药新药临床研究指学原则》(郑筱萸.中药新药临床研究指导原则[M].北京：中国医药科技出版社，2002.)制定：(1)痊愈：症状体征消失或基本消失；(2)显效：症状体征明显改善；(3)有效：症状体征均有好转；(4)无效：症状体征均无明显改善甚或加重。
治疗结果
在治疗1个疗程后，所有患儿均符合痊的标准，并且未观察到明显的不良反应。
Claims (3)
1.一种治疗小儿腹泻的药剂，其特征在于，它是由下列原料药按重量份计制成：
2.根据权利要求1所述的治疗小儿腹泻的药剂，其特征在于，它是由下列原料药按重量份计制成：
3.根据权利要求1或2所述的治疗小儿腹泻的药剂，其特征在于，所述药剂为片剂、分散片、贴剂、胶囊剂或硬胶囊剂。
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| CN104706867A (zh) * | 2015-03-18 | 2015-06-17 | 马亮英 | 一种用于治疗小儿腹泻的药物组分及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101822799A (zh) * | 2010-05-26 | 2010-09-08 | 成都晟铭医药科技有限公司 | 用于治疗腹泻的中药组合物、制剂及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101822799A (zh) * | 2010-05-26 | 2010-09-08 | 成都晟铭医药科技有限公司 | 用于治疗腹泻的中药组合物、制剂及其制备方法 |
Non-Patent Citations (3)
| Title |
|---|
| 常四虎等: "小儿神阙穴贴药治验2则", 《光明中医》, vol. 24, no. 11, 30 November 2009 (2009-11-30), pages 2196 * |
| 谭澹等: "中药辨证敷脐在小儿腹泻中的应用", 《光明中医》, vol. 22, no. 01, 31 January 2007 (2007-01-31), pages 23 - 24 * |
| 赵庆同: "猪苦栋子中毒", 《畜牧与兽医》, no. 5, 31 October 1981 (1981-10-31), pages 45 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104706867A (zh) * | 2015-03-18 | 2015-06-17 | 马亮英 | 一种用于治疗小儿腹泻的药物组分及其制备方法 |
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