CN102527453B - 一种应用于纳米颗粒制备的高并行微流道芯片 - Google Patents
一种应用于纳米颗粒制备的高并行微流道芯片 Download PDFInfo
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- CN102527453B CN102527453B CN201110454345.0A CN201110454345A CN102527453B CN 102527453 B CN102527453 B CN 102527453B CN 201110454345 A CN201110454345 A CN 201110454345A CN 102527453 B CN102527453 B CN 102527453B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
- B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
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Abstract
Description
Claims (11)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110454345.0A CN102527453B (zh) | 2011-12-30 | 2011-12-30 | 一种应用于纳米颗粒制备的高并行微流道芯片 |
PCT/CN2012/000330 WO2013097262A1 (zh) | 2011-12-30 | 2012-03-16 | 一种应用于纳米颗粒制备的高并行微流道芯片 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201110454345.0A CN102527453B (zh) | 2011-12-30 | 2011-12-30 | 一种应用于纳米颗粒制备的高并行微流道芯片 |
Publications (2)
Publication Number | Publication Date |
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CN102527453A CN102527453A (zh) | 2012-07-04 |
CN102527453B true CN102527453B (zh) | 2014-03-12 |
Family
ID=46336196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201110454345.0A Expired - Fee Related CN102527453B (zh) | 2011-12-30 | 2011-12-30 | 一种应用于纳米颗粒制备的高并行微流道芯片 |
Country Status (2)
Country | Link |
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CN (1) | CN102527453B (zh) |
WO (1) | WO2013097262A1 (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103055981A (zh) * | 2012-12-31 | 2013-04-24 | 苏州汶颢芯片科技有限公司 | 一种聚二甲基硅氧烷微流控芯片及其制备方法 |
CN104107734B (zh) * | 2014-07-18 | 2016-03-02 | 华南师范大学 | 一种微流控芯片及自组装的方法 |
CN104225964B (zh) * | 2014-09-17 | 2016-09-28 | 清华大学 | 微流体气泡排除装置及其制备方法以及微流体器件 |
US20190118174A1 (en) * | 2016-03-28 | 2019-04-25 | Nanoimmunotech, S.L. | Microfluidics for analyte detection based on the light to heat conversion properties of metal nanoparticles |
WO2021225599A1 (en) * | 2020-05-08 | 2021-11-11 | Hewlett-Packard Development Company, L.P. | Fluid structure formation via removing sacrificial structures |
CN112641957B (zh) * | 2020-12-31 | 2023-03-14 | 山西铁居环保科技有限公司 | 基于微流控芯片的嵌段共聚物PCL-b-PEO自组装包封金纳米粒的方法 |
CN114849800B (zh) * | 2022-04-15 | 2023-09-29 | 华东师范大学 | 微流控芯片及制备方法和氧化锌纳米棒阵列图案化生长的应用 |
CN114950582B (zh) * | 2022-04-20 | 2023-10-03 | 南京工业大学 | 一种用于合成纳米颗粒的微流控芯片装置及其应用 |
CN116425190B (zh) * | 2023-04-04 | 2024-04-12 | 华东师范大学 | 一种基于微流控芯片原位生长氧化锌纳米棒的方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6210986B1 (en) * | 1999-09-23 | 2001-04-03 | Sandia Corporation | Microfluidic channel fabrication method |
CN101108721A (zh) * | 2007-06-15 | 2008-01-23 | 中国科学院上海微系统与信息技术研究所 | 一种磁性微结构的制作方法 |
CN101187718A (zh) * | 2007-12-07 | 2008-05-28 | 南京邮电大学 | 电控光开关阵列微流控芯片的制作方法 |
CN101544351A (zh) * | 2009-05-08 | 2009-09-30 | 东南大学 | 低维纳米材料高柔性组装芯片及应用方法 |
CN202538793U (zh) * | 2011-12-30 | 2012-11-21 | 北京瑞斯诺生物医药技术有限公司 | 一种应用于纳米颗粒制备的高并行微流道芯片 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6167910B1 (en) * | 1998-01-20 | 2001-01-02 | Caliper Technologies Corp. | Multi-layer microfluidic devices |
JP2005334874A (ja) * | 2004-04-30 | 2005-12-08 | Sharp Corp | マイクロチャネルとその製造方法およびマイクロシステム |
CN101629143B (zh) * | 2008-12-02 | 2011-09-21 | 中国科学院上海微系统与信息技术研究所 | 用于高通量药物筛选的微流控细胞阵列芯片、方法及应用 |
CN101823686B (zh) * | 2010-04-21 | 2012-07-04 | 大连理工大学 | 一种热塑性聚合物多层微流控芯片封合方法 |
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2011
- 2011-12-30 CN CN201110454345.0A patent/CN102527453B/zh not_active Expired - Fee Related
-
2012
- 2012-03-16 WO PCT/CN2012/000330 patent/WO2013097262A1/zh active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6210986B1 (en) * | 1999-09-23 | 2001-04-03 | Sandia Corporation | Microfluidic channel fabrication method |
CN101108721A (zh) * | 2007-06-15 | 2008-01-23 | 中国科学院上海微系统与信息技术研究所 | 一种磁性微结构的制作方法 |
CN101187718A (zh) * | 2007-12-07 | 2008-05-28 | 南京邮电大学 | 电控光开关阵列微流控芯片的制作方法 |
CN101544351A (zh) * | 2009-05-08 | 2009-09-30 | 东南大学 | 低维纳米材料高柔性组装芯片及应用方法 |
CN202538793U (zh) * | 2011-12-30 | 2012-11-21 | 北京瑞斯诺生物医药技术有限公司 | 一种应用于纳米颗粒制备的高并行微流道芯片 |
Non-Patent Citations (7)
Title |
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.2011,79-83. * |
Adv. Mater.> * |
JP特开2005-334874A 2005.12.08 |
Microfluidic Platform for Controlled;Rohit Karnik et al.;《Nano Letters》;20080726;第8卷(第9期);2096-2912 * |
Minsoung Rhee et al..Synthesis of Size-Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single-Layer Microchannels.< * |
Minsoung Rhee et al..Synthesis of Size-Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single-Layer Microchannels.<Adv. Mater.>.2011,79-83. |
Rohit Karnik et al..Microfluidic Platform for Controlled.《Nano Letters》.2008,第8卷(第9期),2096-2912. |
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Publication number | Publication date |
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CN102527453A (zh) | 2012-07-04 |
WO2013097262A1 (zh) | 2013-07-04 |
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Effective date of registration: 20140429 Address after: 510006 Guangdong city of Guangzhou province Panyu District Xiaoguwei Street Outer Ring Road No. 280 Building No. 302, a department of Guangdong Pharmaceutical University Patentee after: Li Gangzhen Patentee after: Tang Min Address before: 100080, room 6, 801 South Street, Haidian District, Beijing, Zhongguancun Patentee before: Beijing Rsinno Biomedicine Technology Co.,Ltd. |
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Granted publication date: 20140312 Termination date: 20161230 |