CN102526529A - Health-care product for treating nephritic syndrome - Google Patents

Abstract

The invention relates to a health-care product for treating nephritic syndrome. The health-care product is prepared by taking American ginseng, codonopsis pilosula, largehead atractylodes rhizome, tuckahoe, yak bone, cinnamomvine bud, lumbricus, safflower, longhairy antenoron herb, corn silk and liquoric root as raw materials.

Description

A kind of health product that are used for the nephrotic syndrome

Technical field

The present invention relates to health product, particularly a kind of health product that are used for the nephrotic syndrome.

Background technology

Chronic nephritis does not have specific medicament, and state of an illness delay is difficult.Chronic nephritis (CGN) has the trend that increases in the incidence rate of China, so early prevention and treatment chronic nephritis and delay it and develop into the attention that chronic renal failure receives people day by day.Mostly chronic nephritis is immune-complex disease (ICD); Except that the basement membrane infringement of immune complex to glomerule; Also have non-immune-mediated to induced renal damage: harden like " HT ", " high filter ", " high blood clotting " and intrinsic artery of kidney make that small artery is narrow, obturation etc.; All can make excess of the kidney matter impaired, cause GBM (GBM) damage.Modern study confirms that proinflammatory cytokine TNF-α and IL-6 are the key factors that causes proliferation of glomerular mesangial cells, sclerosis and kidney disease to worsen, and in CGN patient, serum TNF-α value significantly raises, and is consistent with this research observed result.The treatment nephrotic syndrome does not have specific drug at present.

Summary of the invention

A kind of health product that are used for the nephrotic syndrome of the present invention:

(1) chooses Radix Panacis Quinquefolii 100-200g, Radix Codonopsis 150-250g, Rhizoma Atractylodis Macrocephalae 100-200g, Poria 150-250g, Os Bovis grunniens 100-200g, Rhizoma Dioscoreae bud 1000-2000g, Pheretima 50-150g, Flos Carthami 150-250g, Herba Lysimachiae 150-250g, Stigma Maydis 50-150g, Radix Glycyrrhizae 30-60g;

(2) get the above-mentioned raw materials decocte with water, it is 1.21-1.28 that decoction liquor is concentrated into density;

(3) add ethanol and precipitate, filter, get filtrating, be heated to nothing alcohol flavor and promptly get preparation according to the invention.

A kind of health product that are used for the nephrotic syndrome of the present invention:

Said step (3) adds 85-95% ethanol limit edged and stirs, and when ethanol content reaches 40-60%, medicinal liquid is placed precipitated in 24-48 hour.

A kind of health product that are used for the nephrotic syndrome of the present invention:

The 15-20 of the gross mass of the raw material that the middle amount of water of said step (2) is a step (1) doubly.

The Rhizoma Dioscoreae bud: being to choose well-grown Rhizoma Dioscoreae seedling, cleaning up, under aseptic condition, is the cut-out that 1～2 cm has stem eye with its cutting, obtains the Rhizoma Dioscoreae bud.

Result of use of the present invention is good, can be effective to diseases such as the nephrotic syndrome.

The specific embodiment:

Describe specific embodiment of the present invention in detail,

Embodiment 1:

(1) chooses Radix Panacis Quinquefolii 100g, Radix Codonopsis 150g, Rhizoma Atractylodis Macrocephalae 100g, Poria 150g, Os Bovis grunniens 100g, Rhizoma Dioscoreae bud 1000g, Pheretima 50g, Flos Carthami 150g, Herba Lysimachiae 150g, Stigma Maydis 50g, Radix Glycyrrhizae 30g;

(2) get above-mentioned raw materials and add 15 times of decoctings and boil, it is 1.21 that decoction liquor is concentrated into density,

(3) add 85% ethanol limit edged and stir, reach at 60% o'clock to ethanol content, medicinal liquid is placed precipitated in 24 hours, filter, get filtrating, being heated to does not have the alcohol flavor and promptly gets preparation according to the invention.

Embodiment 2:

(1) chooses Radix Panacis Quinquefolii 200g, Radix Codonopsis 250g, Rhizoma Atractylodis Macrocephalae 200g, Poria 250g, Os Bovis grunniens 200g, Rhizoma Dioscoreae bud 2000g, Pheretima 150g, Flos Carthami 250g, Herba Lysimachiae 250g, Stigma Maydis 150g, Radix Glycyrrhizae 60g;

(2) get above-mentioned raw materials and add 20 times of decoctings and boil, it is 1.28 that decoction liquor is concentrated into density;

(3) add 95% ethanol limit edged and stir, reach at 55% o'clock to ethanol content, medicinal liquid is placed precipitated in 36 hours, filter, get filtrating, being heated to does not have the alcohol flavor and promptly gets preparation according to the invention.

Embodiment 3

Actual therapeutic case of the present invention:

Certain man, the illiteracy, 67 years old, suffered from chronic pyelonephritis 15 years, urgent micturition, frequent micturition, dysurea and urethra scorching hot sense two days are with the soreness of waist, lumbago, malaise.Through routine urianlysis: albumen ±, leukocyte +++, erythrocyte is few, epithelial cell+.Recently owing to be not careful in one's diet, took bean curd in continuous 5 days, caused disease to increase the weight of, having a meal does not have appetite.Take the preparation of embodiment 2, every day 3 times, each 10 grams, continuous 30 days, after 30 days, routine urinalysis showed negative, and appetite recovers, and continues after 60 days, and do not recur half a year.

Case two:

Certain woman 56 years old suffers from acute pyelonephritis March, and urgent micturition, frequent micturition, dysurea and urethra burn feeling are arranged, albumen+, pus cell+, leukocyte ++, erythrocyte is few, and the right renal pelvis B ultrasonic has hydrops, and slight renal pelvis separates.Take the preparation of embodiment 2, every day 3 times, each 10 grams, continuous 20 days, after 20 days, the check routine urinalysis: epithelial cell+, leukocyte is few, and other show negative.Through continuous 20 days, routine urinalysis showed negative again, and check B hydrops obviously changes, and follows up a case by regular visits to and does not recur half a year.

Case three:

Certain man 30 years old after the fatigue of drenching with rain, urgent micturition, frequent micturition and dysurea sense occur in the process of tourism, prominent sense lumbago, and fever, urine examination shows: leukocyte +++, erythrocyte is few, epithelial cell ++, albumen ±, confirm as the trouble acute pyelonephritis.Take the preparation of embodiment 2, every day 3 times, each 10 grams, continuous 15 days, two weeks back check routine urinalysis: show negative.Follow up a case by regular visits to not recurrence after 3 months.

Case four:

Certain man 27 years old because venereal infection, occurs weakly, and waist is ached, sexual hypofunction, ankle and foot Mild edema.Pale tongue, less fur, deep-slow pulse.Urine examination shows: leukocyte ++, erythrocyte is few, epithelial cell+.Take the preparation of embodiment 2, every day 3 times, each 10 grams, continuous 25 days, two weeks back check routine urinalysis: show negative.Edema disappears, and improvement of sexual function detects each item index, has reached clinical recovery.Follow up a case by regular visits to not recurrence after 6 months.The case statistics:

According to the requirement of " provisions for new drugs approval " and " new Chinese medicine clinical research guideline ",

Acute pyelonephritis 30 examples: clinical manifestation is frequent micturition, urgent micturition, dysurea, the heat that occurs together, fear of cold, waist kidney district distending pain.Routine urinalysis microscopy visible red cell, leukocyte, urine protein; Urine cultivate can detect pathogenic bacterium,

Cure: symptom, sign disappearance, blood, normal, 3 feminine genders of midstream urine antibacterial culturing of routine urinalysis;

Effectively: sx, sign and blood, routine urinalysis have improvement, and midstream urine is cultivated or be positive;

Invalid: symptom and blood, the equal no change of routine urinalysis.

Take the preparation of embodiment 2, every day 3 times, each 10 grams continuous 30 days, are cured 25 examples. effective 3 examples, invalid 2 examples.

Claims (3)

1. a kind of health product that are used for the nephrotic syndrome of the present invention is characterized in that:

(1) chooses Radix Panacis Quinquefolii 100-200g, Radix Codonopsis 150-250g, Rhizoma Atractylodis Macrocephalae 100-200g, Poria 150-250g, Os Bovis grunniens 100-200g, Rhizoma Dioscoreae bud 1000-2000g, Pheretima 50-150g, Flos Carthami 150-250g, Herba Lysimachiae 150-250g, Stigma Maydis 50-150g, Radix Glycyrrhizae 30-60g;

(2) get the above-mentioned raw materials decocte with water, it is 1.21-1.28 that decoction liquor is concentrated into density;

(3) add ethanol and precipitate, filter, get filtrating, be heated to nothing alcohol flavor and promptly get health product according to the invention.

2. a kind of health product that are used for the nephrotic syndrome as claimed in claim 1 is characterized in that:

Said step (3) adds 85-95% ethanol limit edged and stirs, and when ethanol content reaches 40-60%, medicinal liquid is placed precipitated in 24-48 hour.

3. a kind of health product that are used for the nephrotic syndrome as claimed in claim 1 is characterized in that:

The 15-20 of the gross mass of the raw material that the middle amount of water of said step (2) is a step (1) doubly.