CN102489070A - Novel traditional Chinese medicine screening and separating device - Google Patents
Novel traditional Chinese medicine screening and separating device Download PDFInfo
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- CN102489070A CN102489070A CN2011103970294A CN201110397029A CN102489070A CN 102489070 A CN102489070 A CN 102489070A CN 2011103970294 A CN2011103970294 A CN 2011103970294A CN 201110397029 A CN201110397029 A CN 201110397029A CN 102489070 A CN102489070 A CN 102489070A
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- chinese medicine
- traditional chinese
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- separating device
- medicine screening
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Abstract
The invention relates to a novel traditional Chinese medicine screening and separating device. Three sealed stainless steel metal containers are arranged from top to down, and mullite-aluminium intermetallic compound porous materials are sandwiched among the containers; soaked traditional Chinese medicine is poured into from an inlet of the upmost metal container; the two metal containers below are sealing devices and are provided with two negative pressure connectors which are connected with a vacuum pump, so that the inner parts of the devices are in a vacuum state, and traditional Chinese medicine liquid is separated more completely; the bottom part of the bottommost metal container is provided with an outlet which is mainly used for collecting liquid after the traditional Chinese medicine is screened and separated. Compared with the common separating instrument, in the novel traditional Chinese medicine screening and separating device, the concentration of effective ingredients of the traditional Chinese medicine is higher and purer. The novel traditional Chinese medicine screening and separating device is simple to operate, high temperature resistant, high voltage resistant and acid and alkali resistant, can be utilized repeatedly, has higher separation and purification concentration, is simple to manufacture, has lower cost, is convenient to carry and move, and is an ideal novel traditional Chinese medicine screening and separating device.
Description
Technical field:
The chemical composition of Chinese medicine is very complicated, contains plurality of active ingredients, its active ingredient of separation screening and further purifying in addition, and obtaining effective monomer is an important content in traditional Chinese medicine research field.Effective Components of Chinese Herb generally is meant the chemical substance with clear and definite chemical structural formula and rerum natura constant; If the concentration of active ingredient is not high; Will strengthen taking dose; Because the existence invalid or part that effectiveness is low can make the easy moisture absorption of Chinese medicine rotten, be difficult to preserve simultaneously, therefore be necessary Effective Components of Chinese Herb is carried out separation screening.In recent years,, demonstrated great application prospect, made traditional Chinese medicine industry more full of life many new technologies, new method having occurred aspect the middle pharmaceutically active ingredient separation screening.
Background technology:
The conventional method of effective component separation and Extraction mainly is to adopt organic solvent extraction earlier, through separation technology such as chromatography, recrystallizations effective component is further purified then, researches and develops into new drug, is used for clinical at last.There is the problem of following aspect in conventional method.At first, in the leaching process organic solvent might with the effective component effect, make it lose original effectiveness.As when adopting alcohol precipitation process, the effective component loss late is sometimes up to 60%.In addition, the use of a large amount of organic solvents has improved production cost, again contaminated environment.The second, the leaching process step is many, and specification requirement is harsh and complicated, and energy consumption is high, and the production cycle is long, particularly when the active constituent content that is extracted is too low, separates the very difficulty that just becomes.The 3rd, non-effective component can not be removed to greatest extent, and enrichment factor is not high enough, and mouthfeel is poor, and clinical efficacy can not be not fully exerted.The 4th, process often adopts high-temperature operation, thereby can cause a large amount of decomposition of thermal sensitivity effective component.The 5th, too pay attention to the effect of single component, make Chinese medicine lose original compound characteristic.The above-mentioned defective of conventional method makes it be difficult to satisfy international market and patient's requirement day by day harsh to drug quality, also because of the too low shortage international competitiveness of new and high technology content.Therefore press for and apply new and effective separation and extraction technology of effective component and instrument.
Summary of the invention:
1, device of the present invention is flexible, and volume is less, is easy to carry, and can be used for scientific experiment; Simple for production, expense is lower.
2, metal material is processed by stainless steel, can high temperature resistant, acid and alkali-resistance, but supercharging and decompression are easy and simple to handle, can use repeatedly.
3, adopt the multilevel hierarchy separation screening, the porous parting material of different stage can be placed in the rustless steel canister junction of three sealings, can the separation screening various objectives and the Chinese medicine of requirement.
4, device of the present invention adopts physical method classifications such as filtration, sedimentation, extraction, absorption, film separation, hierarchical screening to separate, and therefore meets environmental protection, low-carbon (LC) requirement, has a extensive future.
Description of drawings:
Fig. 1 is the new medicine screen selecting and separating mechanism.
Wherein 1: feed liquor is irritated; 2: sealing gasket; 3: go up interface; 4: middle filter; 5: middle interface; 6: little sealing gasket; 7: Intermatallic Ti-Al compound porous material and rubber ring; 8: screw; 9: filter and irritate at the end; 10: end interface; 11: end sealing gasket; 12: Intermatallic Ti-Al compound porous material and rubber ring; 13: base; 14: cross pan head screw (stainless steel).
The specific embodiment:
Adopt the rustless steel canister of three sealings to install from top to bottom, the centre accompanies Intermatallic Ti-Al compound porous material and rubber ring; Chinese medicine through oozing bubble pours into from the inlet of the top canister; Below two canisters be sealing device, and two negative pressure connectors are arranged, connect vavuum pump, make device inside be in vacuum state, traditional Chinese medicine liquid is separated more completely; An outlet is arranged at the bottom of bottom canister, mainly is the liquid of collecting after Chinese medicine screening separates.
Claims (3)
1. the foundation of a new medicine screening and separating instrument: adopt the rustless steel canister of three sealings to install from top to bottom, the centre accompanies Intermatallic Ti-Al compound porous material and rubber ring; Chinese medicine through oozing bubble pours into from the inlet of the top canister; Below two canisters be sealing device, and a negative pressure connector is arranged, connect vavuum pump, make device inside be in vacuum state, traditional Chinese medicine liquid is separated more completely; An outlet is arranged at the bottom of bottom canister, mainly is the liquid of collecting after Chinese medicine screening separates.
2. the characteristic of the separate apparatus of telling according to claim 1 is: all be under the identical situation at study subjects such as experimental drug, reagent, instrument and experiment material; Through rat animal experimental analysis, FDP detection, tissue factor (Tissue Factor; TF) data of detection gained show with results of statistical analysis: new medicine screening and separating instrument is compared with common separate apparatus; Its Chinese medicine useful effect material concentration is more increased, and is purer.
3. the clinical trial meaning of the separate apparatus of telling according to claim 1 is: promptly new medicine screening and separating instrument meets the clinical testing requirement more, more helps Chinese medicine and Chinese medicine compound prescription thereof are purified, and can better launch clinical research.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103970294A CN102489070A (en) | 2011-12-05 | 2011-12-05 | Novel traditional Chinese medicine screening and separating device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103970294A CN102489070A (en) | 2011-12-05 | 2011-12-05 | Novel traditional Chinese medicine screening and separating device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102489070A true CN102489070A (en) | 2012-06-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011103970294A Pending CN102489070A (en) | 2011-12-05 | 2011-12-05 | Novel traditional Chinese medicine screening and separating device |
Country Status (1)
| Country | Link |
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| CN (1) | CN102489070A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6422848A (en) * | 1987-07-15 | 1989-01-25 | Sumitomo Chemical Co | Separation and purification of amino acid |
| CN2675123Y (en) * | 2004-01-09 | 2005-02-02 | 陈晓东 | Decompression apparatus for extracting Chinese medicine |
| CN101665295A (en) * | 2009-05-27 | 2010-03-10 | 开创阳光环保科技发展(北京)有限公司 | Water treatment device, water treatment system and water treatment method thereof |
| CN201578909U (en) * | 2009-12-17 | 2010-09-15 | 吴晓岭 | Traditional Chinese medicine liquid filter device |
-
2011
- 2011-12-05 CN CN2011103970294A patent/CN102489070A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6422848A (en) * | 1987-07-15 | 1989-01-25 | Sumitomo Chemical Co | Separation and purification of amino acid |
| CN2675123Y (en) * | 2004-01-09 | 2005-02-02 | 陈晓东 | Decompression apparatus for extracting Chinese medicine |
| CN101665295A (en) * | 2009-05-27 | 2010-03-10 | 开创阳光环保科技发展(北京)有限公司 | Water treatment device, water treatment system and water treatment method thereof |
| CN201578909U (en) * | 2009-12-17 | 2010-09-15 | 吴晓岭 | Traditional Chinese medicine liquid filter device |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120613 |