CN106422417A - Novel solid-phase extraction column capable of performing suction under negative pressure - Google Patents
Novel solid-phase extraction column capable of performing suction under negative pressure Download PDFInfo
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- CN106422417A CN106422417A CN201611036957.7A CN201611036957A CN106422417A CN 106422417 A CN106422417 A CN 106422417A CN 201611036957 A CN201611036957 A CN 201611036957A CN 106422417 A CN106422417 A CN 106422417A
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- phase extraction
- extraction column
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- liquid storage
- column
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
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- Chemical Kinetics & Catalysis (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
The invention discloses a novel solid-phase extraction column capable of performing suction under negative pressure. The novel solid-phase extraction column comprises a liquid storage bottle, an adsorption filler column and a collection bottle, wherein the liquid storage bottle is arranged on the upper part of the whole solid-phase extraction column; the tail end of the liquid storage bottle is in threaded connection with the adsorption filler column; the adsorption filler column comprises a filler layer, a vacuum cavity and a collecting pipe; the filler layer is arranged at the inner lower end of the adsorption filler column; the collecting pipe is arranged below the adsorption filler column; the vacuum cavity is formed around the collecting pipe; a vacuum suction filtration pipe is arranged at the upper end of the lateral surface of the vacuum cavity; the collection bottle is arranged at the lower part of the whole solid-phase extraction column, and is connected with the adsorption filler column; the vacuum cavity is communicated with the collection bottle; the vacuum suction filtration pipe is connected with an external air pressure gauge and an air extraction device through a rubber pipe. The solid-phase extraction column is simple in structure, small in size, high in practicability and good in sealing performance.
Description
Technical field
The present invention relates to solid phase extraction techniques field, specially a kind of new can negative-pressure ward solid-phase extraction column.
Background technology
SPE is that one kind is effectively micro or trace materials isolation of purified means, is that developed recently gets up a kind of sample
Preconditioning technique, is combined and is developed by liquid-solid extraction and column liquid chromatographic technology, is mainly used in various food, farming animals produce
The sample pre-treatments of target compound in product, environmental sample and biological sample are more permissible compared with traditional liquid-liquid extraction method
Improve the rate of recovery of analyte, more effectively analyte is separated with interfering component, reduce sample pretreatment process, operation letter
Single, save time, laborsaving.
SPE technology is based on liquid-solid phase chromatographic theory, by the way of selective absorption, selective elution, sample is carried out
Enrichment, separation, purification, are a kind of inclusion liquid phase and solid phase physics extraction process；It approx can also be regarded as a kind of simple
Chromatographic process.SPE is the liquid chromatography separation principle using selective absorption and selective elution.More common method is
Make fluid sample solution pass through adsorbent, retain wherein measured matter, then wash away impurity, Ran Houyong from suitable strength solvents
A small amount of solvent elutes rapidly measured matter, thus reaching the purpose that quick separating purifies and concentrates.Also alternative adsorptive hindrance
Impurity, and allow measured matter to flow out；Or adsorbing contaminant and measured matter simultaneously, reuse suitable solvent selectivity wash-out tested
Material, is generally poured sample into SPE pillar after activation, is then pressurizeed using extraction equipment, the side such as vacuumizes or be centrifuged
Method makes sample pass through extraction column, reaches the effect of isolation of purified, but such equipment cost is big compared with high, volume, complex structure, operation
Complex steps, rate of extraction is slower, thus constrains the development further of solid phase extraction techniques.
Content of the invention
It is an object of the invention to provide a kind of new can negative-pressure ward solid-phase extraction column, it is simple to possess structure, affected
Simply, solve the equipment cost height that the solid-phase extraction device of existing negative-pressure ward exists, health check-up is big, and structure is impetuous, extraction speed
The problems such as degree is slower.
For achieving the above object, the present invention provides following technical scheme：A kind of new can negative-pressure ward solid-phase extraction column,
Including liquid storage bottle, adsorption stuffing post, receiving flask, described liquid storage bottle is located at the top of whole solid-phase extraction column, described liquid storage bottle end
Mutually threadeded with described adsorption stuffing post in end, described adsorption stuffing post includes packing layer, vacuum chamber, header, described filler
Layer is located at lower end in described adsorption stuffing post, and described header is located at below described adsorption stuffing post, and described vacuum chamber is located at institute
State header surrounding, the side upper end of described vacuum chamber is provided with vacuum filtration pipe, and described receiving flask is located at whole solid-phase extraction column
Lower section, described receiving flask is connected with described adsorption stuffing post, and described vacuum chamber is connected with described receiving flask.Described vacuum filtration
Pipe is connected by rubber tube with outside air gauge and air extractor.
Preferably, the top of described liquid storage bottle is provided with top cover, and side is provided with scale portion, and bottom is provided with filter.
Preferably, described liquid storage bottle and the junction of adsorption stuffing post are provided with manual sealed fixing device.
Preferably, described receiving flask is conical flask, and the inner tip of receiving flask is provided with screen pack.
Preferably, described liquid-collecting bottle and adsorption stuffing post junction outer end are provided with caulking gum pipe box.
Compared with prior art, beneficial effects of the present invention are as follows：
Provided by the present invention can negative-pressure ward solid-phase extraction column practical, more convenient sample pre-treatments, whole device is adopted
It is fraction movable connection method, facilitate cleaning and the reuse again of whole device；Simultaneously can be according to reality
Sample treatment needs to select different pressure, can meet to greatest extent analysis worker sample isolate and purify to new method,
New Terms set up demand.Relatively existing band die pressing type solid-phase extraction device is expensive, and using complex operation, volume is big,
Present configuration is simple, affected simple, practical.
Brief description
Fig. 1 is present configuration schematic diagram.
In figure：1 liquid storage bottle, 2 adsorption stuffing posts, 3 packing layers, 4 sealed fixing devices, 5 receiving flasks, 6
Rubber sleeve, 7 headers, 8 vacuum chambers, 9 vacuum filtration pipes, 10 air gauges, 11 air extractors, 12 filtrations
Net, 13 scale portions, 14 top covers, 15 filters.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation description is it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of not making creative work
Embodiment, broadly falls into the scope of protection of the invention.
Refer to Fig. 1, the present invention provides a kind of technical scheme：A kind of new can negative-pressure ward solid-phase extraction column, including
Liquid storage bottle 1, adsorption stuffing post 2, receiving flask 5, described liquid storage bottle 1 is located at the top of whole solid-phase extraction column, described liquid storage bottle 1 end
Mutually threadeded with described adsorption stuffing post 2 in end, described adsorption stuffing post 2 includes packing layer 3, vacuum chamber 8, header 7, described
Packing layer 3 is located at lower end in described adsorption stuffing post 2, and described header 7 is located at below described adsorption stuffing post 2, described vacuum
Chamber 8 is located at described header 7 surrounding, and the side upper end of described vacuum chamber 8 is provided with vacuum filtration pipe 9, and described receiving flask 5 is located at whole
The lower section of individual solid-phase extraction column, described receiving flask 5 is connected with described adsorption stuffing post 2, described vacuum chamber 8 and described receiving flask 5
Connection.Described vacuum filtration pipe 9 is connected by rubber tube with outside air gauge 10 and air extractor 11.
The top of described liquid storage bottle 1 is provided with top cover, and side is provided with scale portion 13, and bottom is provided with filter 15, described storage
Liquid bottle 1 is provided with manual sealed fixing device 4 with the junction of adsorption stuffing post 2, and described receiving flask 5 is conical flask, collects
The inner tip of bottle 5 is provided with screen pack 12, and described liquid-collecting bottle 5 is provided with caulking gum pipe box with adsorption stuffing post 2 junction outer end
6.
Operation principle：Add the liquid being extracted, top cover 14 in liquid storage bottle 1, open outside air extractor 11, then
Receiving flask 5 internal pressure reduces, so that the liquid being extracted is pressed downward due to due to inside and outside pressure difference, packing layer 3 absorption extraction
Take the liquid of needs, the liquid extracting flows through screen pack 15 by header 7 and flows to liquid-collecting bottle 5.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, permissible
Understand and can carry out multiple changes, modification, replacement to these embodiments without departing from the principles and spirit of the present invention
And modification, the scope of the present invention be defined by the appended.
Claims (5)
1. a kind of new can negative-pressure ward solid-phase extraction column, including liquid storage bottle（1）, adsorption stuffing post（2）, receiving flask（5）, its
It is characterised by：Described liquid storage bottle（1）It is located at the top of whole solid-phase extraction column, described liquid storage bottle（1）End is filled out with described absorption
Stock column（2）Mutually threaded, described adsorption stuffing post（2）Including packing layer（3）, vacuum chamber（8）, header（7）, described filler
Layer（3）It is located at described adsorption stuffing post（2）Interior lower end, described header（7）It is located at described adsorption stuffing post（2）Lower section, described
Vacuum chamber（8）It is located at described header（7）Surrounding, described vacuum chamber（8）Side upper end be provided with vacuum filtration pipe（9）, described
Receiving flask（5）It is located at the lower section of whole solid-phase extraction column, described receiving flask（5）With described adsorption stuffing post（2）Connect, described true
Cavity（8）With described receiving flask（5）Connection,
Described vacuum filtration pipe（9）With outside air gauge（10）And air extractor（11）Connected by rubber tube.
2. according to claim 1 a kind of new can negative-pressure ward solid-phase extraction column it is characterised in that：Described liquid storage bottle
（1）Top be provided with top cover（14）, side is provided with scale portion（13）, bottom is provided with filter（15）.
3. according to claim 1 a kind of new can negative-pressure ward solid-phase extraction column it is characterised in that：Described liquid storage bottle
（1）With adsorption stuffing post（2）Junction be provided with manual sealed fixing device（4）.
4. according to claim 1 a kind of new can negative-pressure ward solid-phase extraction column it is characterised in that：Described receiving flask
（5）For conical flask, receiving flask（5）Inner tip be provided with screen pack（12）.
5. according to claim 1 a kind of new can negative-pressure ward solid-phase extraction column it is characterised in that：Described liquid-collecting bottle
（5）With adsorption stuffing post（2）Junction outer end is provided with caulking gum pipe box（6）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611036957.7A CN106422417A (en) | 2016-11-23 | 2016-11-23 | Novel solid-phase extraction column capable of performing suction under negative pressure |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611036957.7A CN106422417A (en) | 2016-11-23 | 2016-11-23 | Novel solid-phase extraction column capable of performing suction under negative pressure |
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| CN106422417A true CN106422417A (en) | 2017-02-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201611036957.7A Pending CN106422417A (en) | 2016-11-23 | 2016-11-23 | Novel solid-phase extraction column capable of performing suction under negative pressure |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108490100A (en) * | 2018-02-25 | 2018-09-04 | 云南民族大学 | A kind of small column system of microwave chromatography pre-treatment |
| CN113521804A (en) * | 2021-07-15 | 2021-10-22 | 绍兴市食品药品检验研究院 | Food detects with preventing full-automatic solid phase extraction device of high flux of jam |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202715274U (en) * | 2012-02-14 | 2013-02-06 | 温州科技职业学院 | Simple solid phase extraction (SPE) device |
| CN204193562U (en) * | 2014-07-25 | 2015-03-11 | 新疆农业科学院农业质量标准与检测技术研究所 | A kind of polyamide solid phase extraction cartridge |
| CN105251238A (en) * | 2015-11-13 | 2016-01-20 | 黑龙江省科学院科技孵化中心 | Solid phase extraction column capable of achieving negative pressure suction and using method |
| EP3199233A1 (en) * | 2014-09-25 | 2017-08-02 | Shenzhen Cantonnet Energy Services Co. , Ltd. | Solid phase extraction column, preparation method therefor, and chemical sample pre-processing method based on solid phase extraction column |
-
2016
- 2016-11-23 CN CN201611036957.7A patent/CN106422417A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202715274U (en) * | 2012-02-14 | 2013-02-06 | 温州科技职业学院 | Simple solid phase extraction (SPE) device |
| CN204193562U (en) * | 2014-07-25 | 2015-03-11 | 新疆农业科学院农业质量标准与检测技术研究所 | A kind of polyamide solid phase extraction cartridge |
| EP3199233A1 (en) * | 2014-09-25 | 2017-08-02 | Shenzhen Cantonnet Energy Services Co. , Ltd. | Solid phase extraction column, preparation method therefor, and chemical sample pre-processing method based on solid phase extraction column |
| CN105251238A (en) * | 2015-11-13 | 2016-01-20 | 黑龙江省科学院科技孵化中心 | Solid phase extraction column capable of achieving negative pressure suction and using method |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108490100A (en) * | 2018-02-25 | 2018-09-04 | 云南民族大学 | A kind of small column system of microwave chromatography pre-treatment |
| CN113521804A (en) * | 2021-07-15 | 2021-10-22 | 绍兴市食品药品检验研究院 | Food detects with preventing full-automatic solid phase extraction device of high flux of jam |
| CN113521804B (en) * | 2021-07-15 | 2022-05-20 | 绍兴市食品药品检验研究院 | Food detects with full-automatic solid-phase extraction device of high flux of preventing blockking up |
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Application publication date: 20170222 |