CN102482223B - 制备被芳基取代的吡唑的方法 - Google Patents

制备被芳基取代的吡唑的方法 Download PDF

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Publication number
CN102482223B
CN102482223B CN201080033361.6A CN201080033361A CN102482223B CN 102482223 B CN102482223 B CN 102482223B CN 201080033361 A CN201080033361 A CN 201080033361A CN 102482223 B CN102482223 B CN 102482223B
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China
Prior art keywords
alkyl
formula
aryl
alkoxy
halo
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CN201080033361.6A
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English (en)
Chinese (zh)
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CN102482223A (zh
Inventor
S·帕森诺克
N·卢
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Bayer Intellectual Property GmbH
Bayer CropScience AG
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Bayer CropScience AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CN201080033361.6A 2009-07-23 2010-07-14 制备被芳基取代的吡唑的方法 Active CN102482223B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09166238 2009-07-23
EP09166238.7 2009-07-23
PCT/EP2010/004285 WO2011009551A1 (de) 2009-07-23 2010-07-14 Verfahren zum herstellen von aryl-substituierten pyrazolen

Publications (2)

Publication Number Publication Date
CN102482223A CN102482223A (zh) 2012-05-30
CN102482223B true CN102482223B (zh) 2015-03-04

Family

ID=41509007

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080033361.6A Active CN102482223B (zh) 2009-07-23 2010-07-14 制备被芳基取代的吡唑的方法

Country Status (14)

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US (2) US8299260B2 (enExample)
EP (1) EP2456760B1 (enExample)
JP (1) JP5872467B2 (enExample)
KR (1) KR101701335B1 (enExample)
CN (1) CN102482223B (enExample)
BR (1) BR112012001477A8 (enExample)
DK (1) DK2456760T3 (enExample)
ES (1) ES2474015T3 (enExample)
IL (1) IL217270A0 (enExample)
IN (1) IN2012DN00635A (enExample)
MX (1) MX2012000876A (enExample)
RU (1) RU2012106072A (enExample)
TW (1) TWI482764B (enExample)
WO (1) WO2011009551A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2243777A1 (de) 2009-04-03 2010-10-27 Bayer CropScience AG Verfahren zum Herstellen von Pyridyl-substituierten Pyrazolen
MX2012000876A (es) 2009-07-23 2012-02-01 Bayer Cropscience Ag Procedimiento para la preparacion de pirazoles sustituidos con arilo.
US8242313B2 (en) 2009-07-23 2012-08-14 Bayer Cropscience Ag Alkoxy enones and enamino ketones and a process for preparation thereof
DK2456747T3 (da) * 2009-07-23 2014-07-28 Bayer Cropscience Ag Fremgangsmåde til fremstilling af alkoxyenoner og enaminoketoner
IL278754B2 (en) * 2018-05-21 2023-10-01 Pi Industries Ltd A novel process for the preparation of anthranilic diamides
PT3823953T (pt) * 2018-07-20 2024-12-16 Pi Industries Ltd Um novo processo para a preparação de diamidas antranílicas
IL309501A (en) 2021-08-19 2024-02-01 Syngenta Crop Protection Ag Method for controlling pests resistant to diamide and compounds therefor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999062885A1 (en) * 1998-06-05 1999-12-09 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents
CN1061037C (zh) * 1993-12-22 2001-01-24 拜尔公司 取代的1－芳基吡唑
CN1541206A (zh) * 2001-08-13 2004-10-27 ��Ļ���Ű˾ 取代的二氢3-卤代-1h-吡唑-5-羧酸酯其制备及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE469892T1 (de) * 2001-08-13 2010-06-15 Du Pont Substituierte 1h-dihydropyrazole, ihre herstellung und verwendung
DE102006042437A1 (de) * 2006-03-30 2007-10-04 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden Eigenschaften
DE102006032168A1 (de) * 2006-06-13 2007-12-20 Bayer Cropscience Ag Anthranilsäurediamid-Derivate mit heteroaromatischen Substituenten
MX2012000876A (es) 2009-07-23 2012-02-01 Bayer Cropscience Ag Procedimiento para la preparacion de pirazoles sustituidos con arilo.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1061037C (zh) * 1993-12-22 2001-01-24 拜尔公司 取代的1－芳基吡唑
WO1999062885A1 (en) * 1998-06-05 1999-12-09 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents
CN1541206A (zh) * 2001-08-13 2004-10-27 ��Ļ���Ű˾ 取代的二氢3-卤代-1h-吡唑-5-羧酸酯其制备及应用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Tri¯uoroacetylation of unsymmetrical ketone acetals.A convenient route to obtain alkyl side chain tri¯uoromethylated heterocycles;Helio G. Bonacorso et al.;《Journal of Fluorine Chemistry》;19990702;第99卷;第177-182页 *

Also Published As

Publication number Publication date
IN2012DN00635A (enExample) 2015-08-21
KR101701335B1 (ko) 2017-02-01
DK2456760T3 (da) 2014-07-14
BR112012001477A2 (pt) 2015-09-01
CN102482223A (zh) 2012-05-30
TW201116519A (en) 2011-05-16
WO2011009551A1 (de) 2011-01-27
US8399679B2 (en) 2013-03-19
JP2012533580A (ja) 2012-12-27
EP2456760B1 (de) 2014-05-07
MX2012000876A (es) 2012-02-01
US20110028729A1 (en) 2011-02-03
RU2012106072A (ru) 2013-08-27
KR20120039034A (ko) 2012-04-24
JP5872467B2 (ja) 2016-03-01
US20130018192A1 (en) 2013-01-17
ES2474015T3 (es) 2014-07-08
US8299260B2 (en) 2012-10-30
BR112012001477A8 (pt) 2016-07-12
TWI482764B (zh) 2015-05-01
EP2456760A1 (de) 2012-05-30
IL217270A0 (en) 2016-02-29

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Patentee before: BAYER CROPSCIENCE AG

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Address after: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789

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Address before: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789

Patentee before: BAYER INTELLECTUAL PROPERTY GmbH