CN102470098A - 用于mpi引导的药物递送的刺激-响应性载体 - Google Patents

用于mpi引导的药物递送的刺激-响应性载体 Download PDF

Info

Publication number
CN102470098A
CN102470098A CN2010800299507A CN201080029950A CN102470098A CN 102470098 A CN102470098 A CN 102470098A CN 2010800299507 A CN2010800299507 A CN 2010800299507A CN 201080029950 A CN201080029950 A CN 201080029950A CN 102470098 A CN102470098 A CN 102470098A
Authority
CN
China
Prior art keywords
shell structure
compositions
contrast agent
mpi
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800299507A
Other languages
English (en)
Chinese (zh)
Inventor
D·布丁斯基
J·A·皮克马特
B·施米特
H·格吕尔
S·朗戈埃斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics NV filed Critical Koninklijke Philips Electronics NV
Publication of CN102470098A publication Critical patent/CN102470098A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2010800299507A 2009-07-01 2010-06-25 用于mpi引导的药物递送的刺激-响应性载体 Pending CN102470098A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09164301 2009-07-01
EP09164301.5 2009-07-01
PCT/IB2010/052918 WO2011001351A1 (en) 2009-07-01 2010-06-25 Stimuli-responsive carriers for mpi-guided drug delivery

Publications (1)

Publication Number Publication Date
CN102470098A true CN102470098A (zh) 2012-05-23

Family

ID=42847651

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800299507A Pending CN102470098A (zh) 2009-07-01 2010-06-25 用于mpi引导的药物递送的刺激-响应性载体

Country Status (6)

Country Link
US (1) US20120100079A1 (https=)
EP (1) EP2448557A1 (https=)
JP (1) JP5763631B2 (https=)
CN (1) CN102470098A (https=)
RU (1) RU2561035C2 (https=)
WO (1) WO2011001351A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103357027A (zh) * 2013-08-01 2013-10-23 孙博 一种具有mri示踪效应的纳米微囊
CN107320738A (zh) * 2017-07-12 2017-11-07 福州大学 一种四氧化三锰‑乳白蛋白纳米球及其制备与应用

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393198B2 (en) 2010-03-22 2016-07-19 Signpath Pharma Inc. Intravenous curcumin and derivatives for treatment of neurodegenerative and stress disorders
US10238602B2 (en) 2011-06-03 2019-03-26 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies
US8753674B2 (en) * 2011-06-03 2014-06-17 Signpath Pharma Inc. Liposomal mitigation of drug-induced long QT syndrome and potassium delayed-rectifier current
US10117881B2 (en) 2011-06-03 2018-11-06 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies
US10349884B2 (en) 2011-06-03 2019-07-16 Sighpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel
US12004868B2 (en) 2011-06-03 2024-06-11 Signpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
US10449193B2 (en) 2011-06-03 2019-10-22 Signpath Pharma Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies
US10532045B2 (en) 2013-12-18 2020-01-14 Signpath Pharma, Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
WO2012169973A1 (en) * 2011-06-09 2012-12-13 Agency For Science, Technology And Research A core-shell nanoparticle
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
CA2882978A1 (en) 2012-08-31 2014-03-06 Signpath Pharma Inc. Curcumin-er, a liposomal-plga sustained release nanocurcumin for minimizing qt prolongation for cancer therapy
WO2014090313A1 (en) * 2012-12-13 2014-06-19 Universitaet Ulm Nanoparticle with a molecularly imprinted coating
US20150374855A1 (en) * 2013-02-20 2015-12-31 Topass Gmbh Oral contrast medium for the diagnostic investigation of the gastrointestinal tract by means of mpi
KR20150026613A (ko) * 2013-09-03 2015-03-11 삼성전자주식회사 소수성 물질 및 조영제를 포함하는 리포좀 및 그의 용도
GB201509934D0 (en) * 2015-06-08 2015-07-22 King S College London Nanoparticles
AU2017257496B2 (en) 2016-04-27 2020-05-07 Signpath Pharma, Inc. Prevention of drug-induced atrio-ventricular block
CN109952060B (zh) 2016-07-12 2023-07-18 马格内蒂克因赛特公司 磁性粒子成像
MX2019010045A (es) * 2017-03-03 2019-10-02 Baxalta Inc Metodos para determinar la potencia de preparaciones de virus adeno-asociados.
KR102024273B1 (ko) 2017-03-27 2019-11-04 주식회사 피에프디 약물 작용 관리 장치 및 방법
US11045552B2 (en) 2017-04-04 2021-06-29 International Business Machines Corporation Stimulus-responsive micellar carrier
JP6934833B2 (ja) 2018-03-30 2021-09-15 三菱パワー株式会社 水質モニタリングシステムとそれを備えた蒸気タービンシステム、並びに水質モニタリング方法
US11890488B2 (en) 2019-03-13 2024-02-06 Magnetic Insight, Inc. Magnetic particle actuation
CN112043682B (zh) * 2020-09-19 2022-03-11 新乡医学院 一种基于多孔钆掺杂氧化铁纳米簇的磁性纳米药物载体及其制备方法
US11839458B2 (en) 2021-02-08 2023-12-12 Vanberbilt University Magnetic particle imaging using an ultrasonic driving field

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005077330A1 (en) * 2004-02-17 2005-08-25 The University Of Melbourne Electromagnetic radiation addressable materials
US20070014730A1 (en) * 2005-06-29 2007-01-18 Andreas Briel Compositions containing magnetic iron oxide particles, and use of said compositions in imaging methods
US20090054722A1 (en) * 2007-08-24 2009-02-26 Ryoko Sugano Drug Carrier Containing Magnetic Fine Particles and System Using the Same
WO2009126441A1 (en) * 2008-04-10 2009-10-15 Board Of Regents, The University Of Texas System Compositions and methods for thermo-sensitive nanoparticles and magnetic nanoparticles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
US5534499A (en) 1994-05-19 1996-07-09 The University Of British Columbia Lipophilic drug derivatives for use in liposomes
US6726925B1 (en) 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
US6835394B1 (en) 1999-12-14 2004-12-28 The Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
US7672704B2 (en) * 2002-09-11 2010-03-02 Duke University Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
US8097283B2 (en) * 2004-01-15 2012-01-17 Mount Sinai School Of Medicine Methods and compositions for imaging
TWI314465B (en) * 2005-12-30 2009-09-11 Ind Tech Res Inst Thermosensitive nanostructure for hyperthermia treatment
CZ301067B6 (cs) * 2006-02-24 2009-10-29 Ústav makromolekulární chemie AV CR Superparamagnetické nanocástice na bázi oxidu železa s modifikovaným povrchem, zpusob jejich prípravy a použití
KR20080035926A (ko) * 2006-10-20 2008-04-24 재단법인서울대학교산학협력재단 자성체 나노입자를 함유한 코어-외각 구조의 금 나노입자의자기공명영상의 티2 조영제, 암 진단제 및 암치료제로서의 용도
WO2008099346A1 (en) * 2007-02-16 2008-08-21 Koninklijke Philips Electronics N. V. Method and separator system for separating magnetic particles, separator column for use in a separator system
TWI374761B (en) * 2008-05-13 2012-10-21 Univ Nat Chiao Tung Method for forming a drug container having the magnetic nano single-crystalline capsule

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005077330A1 (en) * 2004-02-17 2005-08-25 The University Of Melbourne Electromagnetic radiation addressable materials
US20070014730A1 (en) * 2005-06-29 2007-01-18 Andreas Briel Compositions containing magnetic iron oxide particles, and use of said compositions in imaging methods
US20090054722A1 (en) * 2007-08-24 2009-02-26 Ryoko Sugano Drug Carrier Containing Magnetic Fine Particles and System Using the Same
WO2009126441A1 (en) * 2008-04-10 2009-10-15 Board Of Regents, The University Of Texas System Compositions and methods for thermo-sensitive nanoparticles and magnetic nanoparticles

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103357027A (zh) * 2013-08-01 2013-10-23 孙博 一种具有mri示踪效应的纳米微囊
CN103357027B (zh) * 2013-08-01 2016-02-10 孙博 一种具有mri示踪效应的纳米微囊
CN107320738A (zh) * 2017-07-12 2017-11-07 福州大学 一种四氧化三锰‑乳白蛋白纳米球及其制备与应用
CN107320738B (zh) * 2017-07-12 2020-06-12 福州大学 一种四氧化三锰-乳白蛋白纳米球及其制备与应用

Also Published As

Publication number Publication date
JP5763631B2 (ja) 2015-08-12
JP2012532120A (ja) 2012-12-13
WO2011001351A1 (en) 2011-01-06
RU2012103347A (ru) 2013-08-10
EP2448557A1 (en) 2012-05-09
RU2561035C2 (ru) 2015-08-20
US20120100079A1 (en) 2012-04-26

Similar Documents

Publication Publication Date Title
CN102470098A (zh) 用于mpi引导的药物递送的刺激-响应性载体
Waheed et al. Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery
CN102970977B (zh) 用于药物或显像剂的脂质双层载体
Hosta-Rigau et al. Cholesterol–a biological compound as a building block in bionanotechnology
CN102149414B (zh) 提供mri对比增强的药物载体
Landon et al. Nanoscale drug delivery and hyperthermia: the materials design and preclinical and clinical testing of low temperature-sensitive liposomes used in combination with mild hyperthermia in the treatment of local cancer
Mallick et al. Liposomes: versatile and biocompatible nanovesicles for efficient biomolecules delivery
Lopes et al. Physical and chemical stimuli-responsive drug delivery systems: targeted delivery and main routes of administration
CN102149371B (zh) 螯合两亲聚合物
ES2733098T3 (es) Sistema portador magnetoenzimático para imagenología y transporte y liberación selectivos de agentes activos
Naziris et al. Stimuli-responsive drug delivery nanosystems: from bench to clinic
WO2011096230A1 (ja) 磁性粒子、及びその製造方法、並びに磁性粒子含有製剤
JP2009519894A (ja) タンパク質ナノ粒子およびその使用
CN103619802B (zh) 脂质模拟物化合物及其用途
EP2067485A1 (en) Drug carrier providing MRI contrast enhancement
Kannadasan et al. A review: nano particle drug delivery system
Li et al. Research Progress on the nano-delivery systems of antitumor drugs
Salave et al. Development of generic liposome products for drug delivery
Sengar Next-Generation Liposomal Drug Delivery Systems: Core Principles, Innovations, and Targeting Strategies
Sharma et al. Magnetic microsphere an emerging drug delivery system
WO2012014163A1 (en) An antigen specific ultrasound contrast medium, a process for the preparation thereof and its uses
Bassous et al. Elastic Liposomes for Drug Delivery
Takahashi et al. A novel and simple type of liposome carrier for recombinant interleukin-2. Kanaoka, E.

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20120523