CN102470098A - 用于mpi引导的药物递送的刺激-响应性载体 - Google Patents

用于mpi引导的药物递送的刺激-响应性载体 Download PDF

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Publication number
CN102470098A
CN102470098A CN2010800299507A CN201080029950A CN102470098A CN 102470098 A CN102470098 A CN 102470098A CN 2010800299507 A CN2010800299507 A CN 2010800299507A CN 201080029950 A CN201080029950 A CN 201080029950A CN 102470098 A CN102470098 A CN 102470098A
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China
Prior art keywords
shell structure
compositions
contrast agent
mpi
composition
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CN2010800299507A
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English (en)
Chinese (zh)
Inventor
D·布丁斯基
J·A·皮克马特
B·施米特
H·格吕尔
S·朗戈埃斯
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Koninklijke Philips NV
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Koninklijke Philips Electronics NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2010800299507A 2009-07-01 2010-06-25 用于mpi引导的药物递送的刺激-响应性载体 Pending CN102470098A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09164301.5 2009-07-01
EP09164301 2009-07-01
PCT/IB2010/052918 WO2011001351A1 (en) 2009-07-01 2010-06-25 Stimuli-responsive carriers for mpi-guided drug delivery

Publications (1)

Publication Number Publication Date
CN102470098A true CN102470098A (zh) 2012-05-23

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CN2010800299507A Pending CN102470098A (zh) 2009-07-01 2010-06-25 用于mpi引导的药物递送的刺激-响应性载体

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Country Link
US (1) US20120100079A1 (https=)
EP (1) EP2448557A1 (https=)
JP (1) JP5763631B2 (https=)
CN (1) CN102470098A (https=)
RU (1) RU2561035C2 (https=)
WO (1) WO2011001351A1 (https=)

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CN103357027A (zh) * 2013-08-01 2013-10-23 孙博 一种具有mri示踪效应的纳米微囊
CN107320738A (zh) * 2017-07-12 2017-11-07 福州大学 一种四氧化三锰‑乳白蛋白纳米球及其制备与应用

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US9393198B2 (en) 2010-03-22 2016-07-19 Signpath Pharma Inc. Intravenous curcumin and derivatives for treatment of neurodegenerative and stress disorders
US10349884B2 (en) 2011-06-03 2019-07-16 Sighpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel
US12004868B2 (en) 2011-06-03 2024-06-11 Signpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
US10449193B2 (en) 2011-06-03 2019-10-22 Signpath Pharma Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies
US10238602B2 (en) 2011-06-03 2019-03-26 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies
WO2012167212A2 (en) * 2011-06-03 2012-12-06 Signpath Pharma Inc. Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current
US10117881B2 (en) 2011-06-03 2018-11-06 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies
WO2012169973A1 (en) * 2011-06-09 2012-12-13 Agency For Science, Technology And Research A core-shell nanoparticle
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
DE112013004278T5 (de) 2012-08-31 2015-05-21 Signpath Pharma Inc. Curcumin-Er, ein liposomales PLGA-Nanocurcumin mit verlängerter oder verzögerter Freisetzung zur Minimierung der QT-Verlängerung für eine Krebstherapie
WO2014090313A1 (en) * 2012-12-13 2014-06-19 Universitaet Ulm Nanoparticle with a molecularly imprinted coating
US20150374855A1 (en) * 2013-02-20 2015-12-31 Topass Gmbh Oral contrast medium for the diagnostic investigation of the gastrointestinal tract by means of mpi
KR20150026613A (ko) * 2013-09-03 2015-03-11 삼성전자주식회사 소수성 물질 및 조영제를 포함하는 리포좀 및 그의 용도
JP6895252B2 (ja) 2013-12-18 2021-06-30 サインパス ファルマ, インク.Signpath Pharma, Inc. 心筋ｉｋｒチャネルの薬剤誘発性阻害のリポソームによる軽減
GB201509934D0 (en) * 2015-06-08 2015-07-22 King S College London Nanoparticles
KR102638618B1 (ko) 2016-04-27 2024-02-21 사인패스 파마 인코포레이티드 약물 유발된 방실 차단의 방지
US10775452B2 (en) 2016-07-12 2020-09-15 Magnetic Insight, Inc. Magnetic particle imaging
BR112019018216A2 (pt) * 2017-03-03 2020-06-23 Baxalta GmbH Métodos para determinar a potência de preparações de vírus adeno-associados
KR102024273B1 (ko) 2017-03-27 2019-11-04 주식회사 피에프디 약물 작용 관리 장치 및 방법
US11045552B2 (en) 2017-04-04 2021-06-29 International Business Machines Corporation Stimulus-responsive micellar carrier
JP6934833B2 (ja) 2018-03-30 2021-09-15 三菱パワー株式会社 水質モニタリングシステムとそれを備えた蒸気タービンシステム、並びに水質モニタリング方法
WO2020186185A1 (en) 2019-03-13 2020-09-17 Magnetic Insight, Inc. Magnetic particle actuation
CN112043682B (zh) * 2020-09-19 2022-03-11 新乡医学院 一种基于多孔钆掺杂氧化铁纳米簇的磁性纳米药物载体及其制备方法
US11839458B2 (en) 2021-02-08 2023-12-12 Vanberbilt University Magnetic particle imaging using an ultrasonic driving field

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WO2005077330A1 (en) * 2004-02-17 2005-08-25 The University Of Melbourne Electromagnetic radiation addressable materials
US20070014730A1 (en) * 2005-06-29 2007-01-18 Andreas Briel Compositions containing magnetic iron oxide particles, and use of said compositions in imaging methods
US20090054722A1 (en) * 2007-08-24 2009-02-26 Ryoko Sugano Drug Carrier Containing Magnetic Fine Particles and System Using the Same
WO2009126441A1 (en) * 2008-04-10 2009-10-15 Board Of Regents, The University Of Texas System Compositions and methods for thermo-sensitive nanoparticles and magnetic nanoparticles

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CZ301067B6 (cs) * 2006-02-24 2009-10-29 Ústav makromolekulární chemie AV CR Superparamagnetické nanocástice na bázi oxidu železa s modifikovaným povrchem, zpusob jejich prípravy a použití
KR20080035926A (ko) * 2006-10-20 2008-04-24 재단법인서울대학교산학협력재단 자성체 나노입자를 함유한 코어-외각 구조의 금 나노입자의자기공명영상의 티2 조영제, 암 진단제 및 암치료제로서의 용도
CN101631619B (zh) * 2007-02-16 2012-06-27 皇家飞利浦电子股份有限公司 用于分离磁性粒子的方法和分离系统，用于分离系统中的分离柱
TWI374761B (en) * 2008-05-13 2012-10-21 Univ Nat Chiao Tung Method for forming a drug container having the magnetic nano single-crystalline capsule

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005077330A1 (en) * 2004-02-17 2005-08-25 The University Of Melbourne Electromagnetic radiation addressable materials
US20070014730A1 (en) * 2005-06-29 2007-01-18 Andreas Briel Compositions containing magnetic iron oxide particles, and use of said compositions in imaging methods
US20090054722A1 (en) * 2007-08-24 2009-02-26 Ryoko Sugano Drug Carrier Containing Magnetic Fine Particles and System Using the Same
WO2009126441A1 (en) * 2008-04-10 2009-10-15 Board Of Regents, The University Of Texas System Compositions and methods for thermo-sensitive nanoparticles and magnetic nanoparticles

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103357027A (zh) * 2013-08-01 2013-10-23 孙博 一种具有mri示踪效应的纳米微囊
CN103357027B (zh) * 2013-08-01 2016-02-10 孙博 一种具有mri示踪效应的纳米微囊
CN107320738A (zh) * 2017-07-12 2017-11-07 福州大学 一种四氧化三锰‑乳白蛋白纳米球及其制备与应用
CN107320738B (zh) * 2017-07-12 2020-06-12 福州大学 一种四氧化三锰-乳白蛋白纳米球及其制备与应用

Also Published As

Publication number Publication date
JP2012532120A (ja) 2012-12-13
JP5763631B2 (ja) 2015-08-12
WO2011001351A1 (en) 2011-01-06
US20120100079A1 (en) 2012-04-26
RU2012103347A (ru) 2013-08-10
EP2448557A1 (en) 2012-05-09
RU2561035C2 (ru) 2015-08-20

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Application publication date: 20120523