CN102462785A - Medicinal composition for treating acquired immune deficiency syndrome viruses and preparation method thereof - Google Patents
Medicinal composition for treating acquired immune deficiency syndrome viruses and preparation method thereof Download PDFInfo
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- CN102462785A CN102462785A CN2010105438847A CN201010543884A CN102462785A CN 102462785 A CN102462785 A CN 102462785A CN 2010105438847 A CN2010105438847 A CN 2010105438847A CN 201010543884 A CN201010543884 A CN 201010543884A CN 102462785 A CN102462785 A CN 102462785A
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Abstract
The invention relates to a medicinal composition for treating acquired immune deficiency syndrome viruses and a preparation method thereof. The medicinal composition is a medicament prepared by the following steps of: carefully choosing sea backthern, Chinese caterpillar fungus, saffron, wild polyrhachis silky ant, corydalis tuber, wild cynomorium coccineum, wild desertliving cistanche, wild earthworm, wild lucid ganoderma, pseudo-ginseng root and isatis root, and refining; drying respectively, smashing, sieving with a 24-mesh sieve, soaking, combining distillates, stirring, and sterilizing; and charging into glass bottles of 250ml and 500ml on a large transfusion production line separately, and sterilizing. A compound water extraction medicament prepared with the method has low cost, a simple production process, a good treatment effect, is convenient to operate when taken as an injection, and is suitable for children, the old, virus carriers and languishers.
Description
Technical field
The present invention relates to pharmaceutical composition of a kind of treatment " HIV " and preparation method thereof.
Background technology
At present, because of environmental pollution, disease is to threaten human the biggest problem.To anti-" HIV " in the market multiple medicine is arranged, but these medicine ubiquities various problems, a part of medicine is very big to the toxicity of human body, even the normal cell in the injury blood of human body; Be difficult to " HIV " effectively control.So; This new therapy preparation of our research and development is through more than ten years clinical pharmacology operation instruction; " HIV " carrier there is good therapeutic effect.
Summary of the invention
In order to excavate China's Chinese crude drug affluent resources, the purpose of this invention is to provide the medicament that the pharmaceutical composition of a kind of treatment " HIV " is processed.This pharmaceutical composition crude drug cost is low, and the confession amount is sufficient.
Another object of the present invention provides the preparation of medicaments method of a kind of compound extract treatment " HIV ".This method technology is simple, and in the refining packing of infusion solutions GMP standard production line, easy to use all-ages.Be a kind of prevention and remarkable, the safer new formulation of treatment " HIV " carrier effect.。
The objective of the invention is to realize through following technical scheme:
The pharmaceutical composition of a kind of treatment " HIV " is characterized in that it is the medicament of being processed by following materials by weight percentage:
Cordyceps 1.7%-2.5%, Fructus Hippophae 32%-33%, Stigma Croci 1-1.5%; The wild ancient cooking vessel Formica fusca 11.7%-12.8% that dashes forward, Rhizoma Corydalis (has another name called: 8.3%-8.8% Rhizoma Corydalis), wild Pheretima 5%-5.5%; Wild Herba Cynomorii 8.3%-8.8%, wild Herba Cistanches 8.3%-8.8%, wild Ganoderma 7.3%-7.8%; Radix Notoginseng 8.3%-8.8%, Radix Isatidis 6.7%-7.7%.
The pharmaceutical composition of treatment " HIV " is processed the method for medicament, be with Fructus Hippophae, Cordyceps, Stigma Croci, the prominent Formica fusca of wild ancient cooking vessel, Rhizoma Corydalis (have another name called: Rhizoma Corydalis), wild Herba Cynomorii, wild Herba Cistanches, wild Pheretima, wild Ganoderma, Radix Notoginseng, Radix Isatidis selected refining → dry → immersion → distillate merging under 25 ℃ of pulverizings → the mistakes 24 mesh sieves choosing back → room temperatures then → with the hot air circulation sterilization tank sterilize → subsequent use; Lead by Chinese medicine is theoretical: monarch, minister, the method reasonable compatibility of helping, making, wherein: [monarch] medicine is: 34.7～37%; [minister] medicine is: 25～27.1%; [assistant] medicine is: 23.9～25.4%; [making] medicine is: 15～16.5%; After the refining packing of infusion solutions GMP standard production line, use.
It is injection that the pharmaceutical composition of above-mentioned treatment " HIV " is processed medicament.
Press the theoretical guiding of Chinese medicine, the pharmaceutical composition of treatment " HIV " is divided into monarch drug, ministerial drug, adjuvant drug, messenger drug.
Monarch drug
(1) Cordyceps: 4-5 month → excavate → peel off outer layer ?brown capsule skin → selected clean → shine dry for several times → leave in ventilate or the refrigerator vial in subsequent use → pulverizings → mistakes 24 mesh sieves select and locate to soak 28 hours → separation under → 25 ℃ of room temperatures and remove impurity → distillate → sterilization → subsequent use
(2) Fructus Hippophae: 10-11 gathers → removes and soak 32 hours → removing impurities → induce separation content → distillate → sterilization → subsequent use under crust → dry → drying → pulverizing → → 25 ℃ of room temperatures of mistake 24 mesh sieves choosing the middle of the month
(3) Stigma Croci: spring, summer, autumn height above sea level is more than 3500 meters → adopt stigma → fine day to pick flowers morning → and indoor winning soak 28 hours → removing impurities → distillate → sterilization → subsequent use under stigma → dry or end temperature oven dry → pulverizing → → 25 ℃ of room temperatures of mistake 24 mesh sieves choosing
More than (1), (2) and (3) kind Chinese medicine be [monarch drug] of this medicament
Ministerial drug
(4) the prominent silky ant of wild ancient cooking vessel: spring, summer, autumn height above sea level is more than 3500 meters → field excavate live body → water purification soak 7 days → biotechnology take good care of 3 days → dry till death → drying → refrigerator deposit subsequent use → pulverized and soaked 20 hours → derivant separation → distillate → sterilization → subsequent use under → 25 ℃ of room temperatures of 24 mesh sieves choosing
(5) Rhizoma Corydalis (have another name called: Rhizoma Corydalis): 5-6 between the month the withered fully back of plant excavated → clean in 5-7 days → put into 80-90 ℃ of boiled water part omitted boil 3-6 minute → pick up immediately to dry to drying → pulverizing → mistake 24 mesh sieves and select immersion 28 hours → removing impurities → distillate → sterilization under → 25 ℃ of room temperatures → subsequent use
(6) wild Pheretima (having another name called: Lumbricus, earthworm etc.): two cloudy extremely frigid zones spring, summer, the autumn → deep-cut soil → pick up Pheretima alive → put into after scuttlebutt → immersion 2-3 days → dry to dry → pulverized and soaked 20 hours → removing impurities → distillate → sterilization → subsequent use under → 25 ℃ of room temperatures of 24 mesh sieves choosing
More than (4), (5) and (6) kind Chinese medicine be [ministerial drug] of this medicament
Adjuvant drug
(7) wild Herba Cynomorii (have another name called: Herba Cynomorii): excavate back → remove selected behind inflorescence and the earth impurity → clean and run through section or cutting → solarizations is stiff tans by the sun → pulverizes the back again and cross 24 mesh sieves and select immersion 32 hours → removing impurities → distillate → sterilization under → 25 ℃ of room temperatures → subsequent use
(8) wild Herba Cistanches: excavate → remove inflorescence → clean earth → dry → cut into serving pieces → dry again → pulverized spring when Seedling is unearthed or just has been unearthed and soak 32 hours → removing impurities → distillate → sterilization → subsequent use under → 25 ℃ of room temperatures of 24 mesh sieves choosing
(9) wild Ganoderma: the impurity of gathering the whole year → remove → wipe out dries in the shade with rotten wood → lower end stem or 40 spends to dry → pulverized to 50 degree and soak 28 hours → removing impurities → distillate → sterilization → subsequent use under → 25 ℃ of room temperatures of 24 mesh sieves choosing
More than (7), (8) and (9) kind Chinese medicine be [adjuvant drug] of this medicament
Messenger drug
(10) Radix Notoginseng (have another name called: Radix Notoginseng): winter and It is the end of summer, just turning into autumn excavate → go fibrous root → tan by the sun to half a year → being used for crumple → tanning by the sun again → repeating several → drying → pulverized soaks 32 hours → removing impurities → distillate → sterilization → subsequent use under → 25 ℃ of room temperatures of 24 mesh sieves choosing
(11) Radix Isatidis: uproot autumn or excavate → fall stem and leaf → clean early winter and dry and deposit drying place → pulverized and soak 28 hours → removing impurities → distillate → sterilization → subsequent use under → 25 ℃ of room temperatures of 24 mesh sieves choosing
More than (10) and (11) kind Chinese medicine be [messenger drug] of this medicament.
In the pharmaceutical composition prescription of the present invention:
(1) Cordyceps: (function cures mainly): cancer-resisting, resisting fatigue, defying age, to suffer from a deficiency of the kidney, soreness of waist and knee joint, after being ill weak, antibiotic, antiviral, antiinflammatory, spontaneous sweating, hemopoietic function and two-ways regulation immunity, improve cellular energy and increase various trace elements.
(2) Fructus Hippophae: (function cures mainly) 1, diffusion suppresses to swell and ache; 2, direct killing sick cell; 3, blocking-up carcinogenic factor; 4, human body immunity improving power; 5, activation normal cell vitality, the direct killing sick cell induces sick cell to commit suiside, the repair cell damage.
(3) Stigma Croci: (function cures mainly): anemia body void, general aching, traumatic injury, neurasthenia, palpitation with fear is demented, suppress cell DNA and RNA is synthetic, stops the generation of virocyte.Regulating menstruation, invigorate blood circulation, eliminate the phlegm, pain relieving, be used for removing heat from the liver, blood stasis stasis, interior external haemorrhage, pneumonia, hepatopathy good medicine, the operation of balance human body negative and positive mechanism of qi.
(4) the prominent Formica fusca of wild ancient cooking vessel: (function cures mainly): the kidney invigorating and essence nourishing, dredge the meridian passage, removing toxic substances and promoting subsidence of swelling.Polyhachis vicina Roger, containing with proline, alanine, glutamic acid and serine is master's composition such as multiple fatty acid and protein.Effects such as insomnia and dreamful sleep, impotence and seminal emission, apoplectic hemiplegia, lupus erythematosus, scleroderma, dermatomyositis, carbuncle furuncle, venom, rheumatism, rheumatoid arthritis and hepatoprotective, diabetes, hypertension, hyperlipidemia, slow down aging.
(5) Rhizoma Corydalis (have another name called: Rhizoma Corydalis): (function cures mainly): be used for each qi depression to blood stasis of the whole province the pain, dysmenorrhea, amenorrhea, the disease purplish or white patches on the skin, postpartum stagnation, injury from falling down, hernia is had a pain, promoting blood circulation to remove blood stasis, the effect of regulating QI to relieve pain.
(6) wild Pheretima (having another name called: Lumbricus, earthworm etc.): (function cures mainly): symptoms such as calentura mania and irritation, infantile convulsion, cough, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, hemiplegia.External is coated with diseases such as erysipelas, dermatitis rhus.
1. clearing heat for calming endogenous wind: cure mainly high fever and faint from fear, wind symptom is twitched.
2. lung heat clearing Dingchuan: can control the asthma of lung-heat productive cough, better to lung-heat type bronchial asthma curative effect.
3. inducing diuresis for treating stranguria syndrome: be applicable to damp invasion of lower energizer, the puckery pain of pyretic stranguria.
4. current meridians: the available swollen swelling pain of pyretic arthralgia joint of controlling, compatibility replenishing qi and promoting blood flow medicine is usually used in blood stasis due to qi deficiency, unfavorable, the hemiplegia aphasiac of meridians.
(7) wild Herba Cynomorii (has another name called: Herba Cynomorii): (function cures mainly): put down in writing according to Compendium of Material Medica: sweet, warm, nontoxic.Big nourishing YIN gas, benefiting essence-blood, sharp stool.Moisturize nourishing muscle and tendon, control wither a little less than.Impotence and premature ejaculation, the moon the decline weak deficiency of YIN of Sanguis Draxonis, gas, constipation due to dry stool, hematuria, fatigue and weak, limbs pain, menoxenia, insomnia forgetfulness, obviously anti-cancer, antiviral and delaying senility function.
(8) wild Herba Cistanches (function cures mainly): kidney yang deficiency, essence and blood loss, sexual impotence, seminal emission, chills and pain of the waist and kness, tinnitus order flower, foul leukorrhea, frequent micturition, delayed period, metrorrhagia, sterility and infertility, dryness of the intestine constipation, ability enhancing immunity; The adjustment endocrine promotes metabolism; Promote growth promoter; Demonstrate the strong effect of androgen appearance, can antiviral and defying age and radiation resistance have the good reputation of " desert Radix Ginseng ", in history with regard to the treasure of various countries, the Western Regions as last tribute imperial court.It is sweet and warm in nature, salty and matter profit, and it is not dry to have a YANG invigorating, and the logical kidney yang the kidney invigorating of temperature is empty; Nourishing YIN is oiliness.Often take and have strong effect prolongation sex time, the miraculous effects of very fast thicker antisecosis!
(9) wild Ganoderma: (function cures mainly): Ganoderma; Sweet, flat.GUIXIN, lung, liver, kidney channel.Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, the breath heart swells and ache etc.When animal pharmacology is tested, show: Ganoderma has phlegm-dispelling functions to nervous system, in addition, also has hepatoprotective, improves immunologic function, antibiosis and antiviral functions.Calm, analgesic activity; Hypoxia-bearing capability.So wild Ganoderma can be used for treating the dysfunction that chronic poisoning, all kinds of liver cause.Promote diseases such as liver is dizzy, weak, nauseating to metabolism, the elimination of drug toxicity, uncomfortable liver area.To the high fat of blood patient, can obviously reduce cholesterolemia, lipoprotein and triglyceride, vessel softening.The Ganoderma polypeptide; 16 seed amino acids, two-way conciliation bodily fuctions, defying age.The treatment diabetes: the principle of Ganoderma blood sugar lowering is owing to promote the utilization of tissue to sugar.The instead insulin suppresses disengaging of fatty acid after taking Ganoderma, can improve symptoms such as blood glucose, glucose in urine.
Its pharmacological effect effect is summarized as follows at present:
One, antitumor, control cancer and immunoregulation effect
Two, blood pressure lowering, hypoglycemic activity
Three, protect the liver, liver protection effect
Four, defying age, skin care, the effect of conciliation endocrine
Five, antiinflammatory, antiviral, analgesic activity
Six, protection heart effect
Seven, blood coagulation resisting function
This shows the effect and the medical value of wild Ganoderma!
(10) Radix Notoginseng (has another name called: Radix Notoginseng): (function cures mainly): dissipating blood stasis hemostasis, subduing swelling and relieving pain.Be used for various inside and outside hemorrhage, breast ventral spine pain, tumbling and swelling.Removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation.
" Chinese Medicine voluminous dictionary " record:
" the Radix Notoginseng function is enriched blood, and blood stasis removing decreases, hemostasis, can lead to can mend, effect well, most precious person in the side's of being medicine.Radix Notoginseng eats something rare, eliminating blood stasis to promote regeneration of blood, subduing swelling and relieving pain, and have hemostasis not stay blood stasis, new advantage is not hindered in promoting the circulation of blood; But ripe clothes tonification is healthy and strong.Antitumor, defying age, antioxidation, blood fat reducing and cholesterol, the liver protecting, clots absorbing blood and hold back fresh blood; Title " the refreshing medicine that stops blooding ".
(11) Radix Isatidis (function cures mainly): antibiosis and antiviral functions: the Isatis indigotica Fort. root all has anti-prevention and antibacterial action to various antibacterials.Infusion all has inhibitory action to hay liver bacterium, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, paratyphoid fever hepatitis A bacterium, dysentery, bacillus, bacillus enteritidis etc.And it is obvious to the Hemolytic streptococcus effect.Heat and toxic materials clearing away medicine: blood-cooling drugs.Heat clearing away, detoxifcation, removing heat from blood, sore-throat relieving, measles, hepatitis, influenza etc.
Above compatibility is learned according to NF, Chinese Chinese medicine, modern Chinese medicine does not have taboo raw material Chinese herbal medicine in the pharmacopeia such as voluminous dictionary, Compendium of Material Medica, summarize as follows:
Crude drug treatment range of application
Cordyceps: cancer-resisting, resisting fatigue, to suffer from a deficiency of the kidney, impotence and seminal emission, soreness of waist and knee joint, after being ill weak, chronic cough is weak, phthisical cough expectorant blood, spontaneous sweating, hemopoietic function.Two-ways regulation immunity improves cellular energy, and Cordyceps extract has clear and definite inhibition, the effect of killing tumor cell.Apparent its Cordyceps, Fructus Hippophae, Stigma Croci are monarch drug in the prescription: the carrier of its anti-virus AIDS virus resisting, resisting fatigue, antitumor, effects such as enhancing immunity.Stigma Croci: to cerebral thrombosis, vasculitis, myocardial infarction, the anemia body is empty, puerperal congestion, general aching, traumatic injury, the neurasthenia, it is demented to palpitate with fear.It is synthetic to suppress sick cell DNA and RNA, stops the generation of tumor.Regulating menstruation is invigorated blood circulation, blood stasis dispelling, and pain relieving is used for removing heat from the liver, blood stasis stasis, interior external haemorrhage, pneumonia, hepatopathy good medicine.The balance human body, the operation of negative and positive mechanism of qi.Rhizoma Corydalis), the prominent Formica fusca of wild Pheretima (having another name called: Lumbricus, earthworm etc.), wild ancient cooking vessel allocating Rhizoma Corydalis once more (has another name called:; The kidney invigorating and essence nourishing, dredge the meridian passage, removing toxic substances and promoting subsidence of swelling.Polyhachis vicina Roger, containing with proline, alanine, glutamic acid and serine is master's composition such as multiple fatty acid and protein.Effects such as insomnia and dreamful sleep, impotence and seminal emission, apoplectic hemiplegia, lupus erythematosus, scleroderma, dermatomyositis, carbuncle furuncle, venom, rheumatism, rheumatoid arthritis and hepatoprotective, diabetes, hypertension, hyperlipidemia, slow down aging.Rhizoma Corydalis (have another name called: Rhizoma Corydalis): be used for pain of each qi depression to blood stasis of whole body, dysmenorrhea, amenorrhea, the disease purplish or white patches on the skin, postpartum stagnation, injury from falling down, hernia is had a pain, promoting blood circulation to remove blood stasis, the effect of regulating QI to relieve pain.Wild Pheretima (having another name called: Lumbricus, earthworm etc.): symptoms such as calentura mania and irritation, infantile convulsion, cough, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, hemiplegia.External is coated with diseases such as erysipelas, dermatitis rhus.Go up monarch drug for the ministerial drug cooperation for these three kinds and improve the curative effect of medication greatly; Herba Cynomorii), wild Herba Cistanches, wild Ganoderma be better: Ganoderma increasing the wild Herba Cynomorii of adjuvant drug again (has another name called:; Sweet, flat.GUIXIN, lung, liver, kidney channel.Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, the breath heart swells and ache etc.When animal pharmacology is tested, show: Ganoderma has phlegm-dispelling functions to nervous system, in addition, also has hepatoprotective, improves immunologic function, antibiosis and antiviral functions.Calm, analgesic activity; Hypoxia-bearing capability.So wild Ganoderma can be used for treating the dysfunction that chronic poisoning, all kinds of liver cause.Promote diseases such as liver is dizzy, weak, nauseating to metabolism, the elimination of drug toxicity, uncomfortable liver area.To the high fat of blood patient, can obviously reduce cholesterolemia, lipoprotein and triglyceride, vessel softening.The Ganoderma polypeptide; 16 seed amino acids, two-way conciliation bodily fuctions, defying age.The treatment diabetes: the principle of Ganoderma blood sugar lowering is owing to promote the utilization of tissue to sugar.The instead insulin suppresses disengaging of fatty acid after taking Ganoderma, can improve symptoms such as blood glucose, glucose in urine.Wild Herba Cynomorii (have another name called: Herba Cynomorii): the kidney invigorating intestine moistening, control sexual impotence, hematuria, the blood depletion constipation, the waist knee flaccidity, the empty deficiency of losing of essence and blood, antiinflammatory improves immunity, the anti-ageing effect of waiting for a long time.Wild Herba Cistanches: kidney yang deficiency, essence and blood loss, sexual impotence, seminal emission, chills and pain of the waist and kness, tinnitus order flower, foul leukorrhea, frequent micturition, delayed period, metrorrhagia, sterility and infertility, dryness of the intestine constipation, ability enhancing immunity; The adjustment endocrine promotes metabolism; Promote growth promoter; Demonstrate the strong effect of androgen appearance, ability antiviral and defying age and radiation resistance; Have the good reputation of " desert Radix Ginseng ", in history with regard to the treasure of various countries, the Western Regions as last tribute imperial court.It is sweet and warm in nature, salty and matter profit, and it is not dry to have a YANG invigorating, and the logical kidney yang the kidney invigorating of temperature is empty; Nourishing YIN is oiliness.Often take and have strong effect prolongation sex time, the miraculous effects that comparatively fast regain one's strength! In sum: the adjuvant drug compatibility that monarch, minister addition are held up, prepare messenger drug again: Radix Notoginseng (has another name called: Radix Notoginseng): dissipating blood stasis hemostasis, subduing swelling and relieving pain.Be used for various inside and outside hemorrhage, breast ventral spine pain, tumbling and swelling.Removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation." Chinese Medicine voluminous dictionary " record: " the Radix Notoginseng function is enriched blood, and blood stasis removing decreases, hemostasis, can lead to can mend, effect well, most precious person in the side's of being medicine.Radix Notoginseng eats something rare, eliminating blood stasis to promote regeneration of blood, subduing swelling and relieving pain, and have hemostasis not stay blood stasis, new advantage is not hindered in promoting the circulation of blood; But ripe clothes tonification is healthy and strong.Antitumor, defying age, antioxidation, blood fat reducing and cholesterol, the liver protecting, clots absorbing blood and hold back fresh blood; Title " refreshing medicine stops blooding ".Radix Isatidis: antibiotic, antivirus action: the Isatis indigotica Fort. root all has anti-prevention and antibacterial action to various antibacterials.Infusion all has inhibitory action to hay liver bacterium, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, paratyphoid fever hepatitis A bacterium, dysentery, bacillus, bacillus enteritidis etc.And it is obvious to the Hemolytic streptococcus effect.Heat and toxic materials clearing away medicine: blood-cooling drugs.Heat clearing away, detoxifcation, removing heat from blood, sore-throat relieving, measles, hepatitis, influenza etc.
Lead according to pharmacopeia such as Compendium of Material Medica, Chinese medicine theory: monarch, minister, the method reasonable compatibility of helping, making; By [monarch] [minister] [assistant] [making] prescription, wherein:
[monarch] medicine is: 34.7～37%;
[minister] medicine is: 25～27.1%;
[assistant] medicine is: 23.9～25.4%;
[making] medicine is: 15～16.5%; Mix thoroughly as one batch, dilution is sub-packed in 250ml/ bottle or 500ml/ bottle; Vial is used the qualified back of sterility test again.
The present invention's [curing mainly]: preventing virus infection, AIDS virus resisting, antibiotic, lung moistening liver-nourishing kidney-boosting, blood circulation promoting and blood stasis dispelling, resisting fatigue, defying age, improve T lymphocytes in human body immunologic function and bone-marrow-derived lymphocyte humoral immune function rapidly.
Advantage of the present invention:
It is low that the compound recipe water of the present invention's preparation is carried reagent cost, and production technology is simple, and therapeutic effect is good, and easy to operate as injection, the scope of application is extensive, and child, old man, virus are carried the patient, languisher all injectables use, and is evident in efficacy.Next medicine no side effects, cellular environment and human body environment that its active ingredient scalable is disorderly recover the gene normal function, avoid the influence of Western medicine side reaction to human body, can improve the immunologic function of human body, and the patient is easy to accept.
The specific embodiment
Below in conjunction with embodiment the present invention is remake further description:
Embodiment 1:
Get Cordyceps 2kg, Fructus Hippophae 32kg, Stigma Croci 1.0kg, the prominent ?Formica fusca 11.7kg of wild ancient cooking vessel, Rhizoma Corydalis 8.3kg, wild Pheretima 5.0kg, wild Herba Cynomorii 8.5kg, wild Herba Cistanches 8.5kg, wild Ganoderma 7.8kg, Radix Notoginseng 8.3kg and Radix Isatidis 7.2kg; Selected refining; After proceeding to drying respectively; Pulverize, cross that 25 ℃ of the choosings of 24 mesh sieves, room temperature are soaked down, distillation merges 11 kinds of distillates then and mixes thoroughly, dilutes packing by [monarch] [minister] [assistant] [making] prescription and sterilize, wherein:
[monarch] medicine is: 35%
[minister] medicine is: 25%
[assistant] medicine is: 24.5%
[making] medicine is: 15.5%
Mix thoroughly as one batch, dilution is sub-packed in 250ml/ bottle or 500ml/ bottle; Vial is used the qualified back of sterility test again.
Embodiment 2:
Get Cordyceps 2.0kg, Fructus Hippophae 32.0kg, Stigma Croci 1.5kg, the prominent ?Formica fusca 12.0kg of wild ancient cooking vessel, Rhizoma Corydalis 8.5kg, wild Pheretima 5.0kg, wild Herba Cynomorii 8.0kg, wild Herba Cistanches 8.0kg, wild Ganoderma 7.5kg, Radix Notoginseng 8.5kg, Radix Isatidis 7.5kg; Selected refining; After proceeding to drying respectively; Pulverize, cross that 25 ℃ of the choosings of 24 mesh sieves, room temperature are soaked down, distillation merges 11 kinds of distillates then and mixes thoroughly, sterilizes by [monarch] [minister] [assistant] [making] prescription dilution packing again, wherein: can be with obtaining after the following method cooperation
[monarch] medicine is: 35.5%
[minister] medicine is: 25.5%
[assistant] medicine is: 23%
[making] medicine is: 16%
Mix thoroughly as one batch, dilution is sub-packed in 250ml/ bottle or 500ml/ bottle; Vial is used the qualified back of sterility test again.
Embodiment 3:
Get Cordyceps 2.0kg, Fructus Hippophae 32kg, Stigma Croci 1.0kg, the prominent ?Formica fusca 11.5kg of wild ancient cooking vessel, Rhizoma Corydalis 8.5kg, wild Pheretima 5.0kg, wild Herba Cynomorii 8.3kg, wild Herba Cistanches 8.3kg, wild Ganoderma 7.4kg, Radix Notoginseng 8.3kg and Radix Isatidis 6.7kg; Selected refining; After proceeding to drying respectively; Pulverize, cross that 25 ℃ of the choosings of 24 mesh sieves, room temperature are soaked down, distillation merges 11 kinds of distillates then and mixes thoroughly, dilutes packing by [monarch] [minister] [assistant] [making] prescription and sterilize, wherein:
[monarch] medicine is: 35.0%
[minister] medicine is: 25.0%
[assistant] medicine is: 24.%
[making] medicine is: 15.0%
Mix thoroughly as one batch, dilution is sub-packed in 250ml/ bottle or 500ml/ bottle; Vial is used the qualified back of sterility test again.
Embodiment 4:
Get Cordyceps 2.0kg, Fructus Hippophae 32.5kg, Stigma Croci 1.5kg, the prominent ?Formica fusca 11.7kg of wild ancient cooking vessel, Rhizoma Corydalis 8.3kg, wild Pheretima 5.1kg, wild Herba Cynomorii 8.3kg, wild Herba Cistanches 8.3kg, wild Ganoderma 7.3kg, Radix Notoginseng 8.8kg and Radix Isatidis 6.7kg; Selected refining; After proceeding to drying respectively; Pulverize, cross that 25 ℃ of the choosings of 24 mesh sieves, room temperature are soaked down, distillation merges 11 kinds of distillates then and mixes thoroughly, dilutes packing by [monarch] [minister] [assistant] [making] prescription and sterilize, wherein:
[monarch] medicine is: 35.5%
[minister] medicine is: 25.1%
[assistant] medicine is: 23.9%
[making] medicine is: 16.5%
Mix thoroughly as one batch, dilution is sub-packed in 250ml/ bottle or 500ml/ bottle; Vial is used the qualified back of sterility test again.
Embodiment 5:
Cordyceps 1.7%-2.5%, Fructus Hippophae 32%-33%, Stigma Croci 1.0-1.5%; The wild ancient cooking vessel Formica fusca 11.7%-12.8% that dashes forward, Rhizoma Corydalis (has another name called: 8.3%-8.8% Rhizoma Corydalis), wild Pheretima 5.0%-5.5%; Wild Herba Cynomorii 8.3%-8.8%, wild Herba Cistanches 8.3%-8.8%, wild Ganoderma 7.3%-7.8%; Radix Notoginseng 8.3%-8.8%, Radix Isatidis 6.7%-7.7%.
Get Cordyceps 2.0kg, Fructus Hippophae 32kg, Stigma Croci 1.0kg, the prominent ?Formica fusca 11.7kg of wild ancient cooking vessel, Rhizoma Corydalis 8.3kg, wild Pheretima 5.0kg, wild Herba Cynomorii 8.5kg, wild Herba Cistanches 8.8kg, wild Ganoderma 7.7kg, Radix Notoginseng 8.5kg and Radix Isatidis 7.5kg; Selected refining; After proceeding to drying respectively; Pulverize, cross that 25 ℃ of the choosings of 24 mesh sieves, room temperature are soaked down, distillation merges 11 kinds of distillates then and mixes thoroughly, dilutes packing by [monarch] [minister] [assistant] [making] prescription and sterilize, wherein:
[monarch] medicine is: 35%
[minister] medicine is: 25%
[assistant] medicine is: 25%
[making] medicine is: 15%
Mix thoroughly as one batch, dilution is sub-packed in 250ml/ bottle or 500ml/ bottle; Vial is used the qualified back of sterility test again.
Claims (3)
1. the pharmaceutical composition of a treatment " HIV " is characterized in that it is the medicament of being processed by following materials by weight percentage:
Cordyceps 1.7%-2.5%, Fructus Hippophae 32%-33%, Stigma Croci 1-1.5%; The wild ancient cooking vessel Formica fusca 11.7%-12.8% that dashes forward, Rhizoma Corydalis 8.3%-8.8%, wild Pheretima 5%-5.5%; Wild Herba Cynomorii 8.3%-78.8%, wild Herba Cistanches 8.3%-8.8%, wild Ganoderma 7.3%-7.8%; Radix Notoginseng 8.3%-8.8%, Radix Isatidis 6.7%-7.7%.
2. the pharmaceutical composition of a kind of according to claim 1 treatment " HIV " is processed the method for medicament, it is characterized in that with the prominent Formica fusca of Fructus Hippophae, Cordyceps, Stigma Croci, wild ancient cooking vessel, Rhizoma Corydalis (have another name called: Rhizoma Corydalis), wild Herba Cynomorii, wild Herba Cistanches, wild Pheretima, wild Ganoderma, Radix Notoginseng, Radix Isatidis selected refining → dry → then immersion → distillate under 25 ℃ of pulverizings → the mistakes 24 mesh sieves choosing back → room temperatures → with the hot air circulation sterilization tank sterilize → subsequent use; Lead by Chinese medicine is theoretical: monarch, minister, the method reasonable compatibility of helping, making, use after the refining packing of infusion solutions GMP standard production line.
3. the pharmaceutical composition of a kind of according to claim 1 treatment " HIV ", it is characterized in that processing medicament is injection.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010105438847A CN102462785A (en) | 2010-11-11 | 2010-11-11 | Medicinal composition for treating acquired immune deficiency syndrome viruses and preparation method thereof |
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| CN2010105438847A CN102462785A (en) | 2010-11-11 | 2010-11-11 | Medicinal composition for treating acquired immune deficiency syndrome viruses and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106138163A (en) * | 2016-07-29 | 2016-11-23 | 桂林淮安天然保健品开发有限公司 | A kind of pharmaceutical composition treating acquired immune deficiency syndrome (AIDS) |
| CN106138162A (en) * | 2016-07-29 | 2016-11-23 | 桂林淮安天然保健品开发有限公司 | The pharmaceutical composition for the treatment of acquired immune deficiency syndrome (AIDS) |
-
2010
- 2010-11-11 CN CN2010105438847A patent/CN102462785A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106138163A (en) * | 2016-07-29 | 2016-11-23 | 桂林淮安天然保健品开发有限公司 | A kind of pharmaceutical composition treating acquired immune deficiency syndrome (AIDS) |
| CN106138162A (en) * | 2016-07-29 | 2016-11-23 | 桂林淮安天然保健品开发有限公司 | The pharmaceutical composition for the treatment of acquired immune deficiency syndrome (AIDS) |
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Application publication date: 20120523 |