CN102445553B - Blending incubation device - Google Patents
Blending incubation device Download PDFInfo
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- CN102445553B CN102445553B CN201010507038.XA CN201010507038A CN102445553B CN 102445553 B CN102445553 B CN 102445553B CN 201010507038 A CN201010507038 A CN 201010507038A CN 102445553 B CN102445553 B CN 102445553B
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- reaction utensil
- blending incubation
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Abstract
The invention discloses and a kind of blending incubation device is provided, comprising: malleation source of the gas; And gas outlet, be communicated with described malleation source of the gas by conduit; In addition, also comprise thermostat, be arranged in the path between described malleation source of the gas and described gas outlet, for controlling the temperature of the gas that described gas outlet exports.According to the blending incubation device of the embodiment of the present invention, reaction efficiency and the reaction velocity of reagent and sample effectively can be improved.
Description
Technical field
The present invention relates to a kind of blending incubation device, particularly relate to a kind of blending incubation device for analytical test.
Background technology
In the various analytical tests of such as blood type analysis, fully whether reagent and sample (such as blood sample) result of reacting analyzing (such as blood type analysis) play an important role, and reagent and sample whether fully react with its mixability and temperature relevant.Storage temperature due to reagent is generally at 2 DEG C-8 DEG C, so temperature when reagent mixes with the sample of such as blood sample compares the end, sometimes also there will be condensation.
For full-automatic blood type analytical instrument, only have evenly mixing device at present and constant temperature process do not carried out to it, only making it hatch by environment temperature.Cause the concrete shortcomings of existing blood type analytical instrument thus, such as the reaction time is long, and may produce condensation.
Therefore, need a kind of reaction efficiency and the reaction velocity that can improve the sample of reagent and such as blood sample, can the blending incubation device of effective Reaction time shorten.
Summary of the invention
The object of the invention is the defect existed to overcome prior art, a kind of reaction efficiency of sample and the blending incubation device of reaction velocity that can improve reagent and such as blood sample are provided.In order to realize this purpose, the technical solution used in the present invention is as follows.
According to the first aspect of the embodiment of the present invention, a kind of blending incubation device is provided, comprises: malleation source of the gas; And gas outlet, be communicated with described malleation source of the gas by conduit; In addition, also comprise thermostat, be arranged in the path between described malleation source of the gas and described gas outlet, for controlling the temperature of the gas that described gas outlet exports.
In one embodiment, described blending incubation device also comprises filtrator, is arranged in the path between described malleation source of the gas and described gas outlet, for filtering the gas from described malleation source of the gas.In one embodiment, preferably, described filtrator is arranged in the path between described malleation source of the gas and described thermostat.
In one embodiment, described blending incubation device also comprises mechnical oscillator, and this mechnical oscillator comprises further: drive motor; Cam, connects with the output shaft of described drive motor; Spring base, one end of spring wherein is configured to by described actuated by cams; And vibrating mass, be connected to the other end of the spring in described spring base, and be configured to contact with reaction utensil base band.
In one embodiment, described blending incubation device also comprises hertz oscilltor, and this hertz oscilltor comprises further: solenoid; Spring, one end connects with described solenoid; And vibrating mass, be connected to the other end of described spring, and be configured to contact with reaction utensil base band.
In one embodiment, described blending incubation device also comprises ultrasonator, and this ultrasonator comprises further: electro coupled oscillator; Transducer, connects with described electro coupled oscillator; And ultrasonic probe, connect with described transducer, and be configured to be positioned at reaction utensil near baseband.
In one embodiment, preferably, described gas outlet is configured to be on the arc-shaped edges of reaction utensil concave surface, and makes outgassing direction become predetermined angular along in reaction utensil orientation with plane residing for reaction utensil.
In one embodiment, further preferably, described gas outlet is configured to make outgassing direction perpendicular to plane residing for reaction utensil and is in the middle part of reaction utensil.
In one embodiment, described thermostat comprises further: heat pipe; For passing through the gas from described malleation source of the gas; Well heater, is positioned near described heat pipe, for heating described heat pipe; And temperature sensor, for sensing the gas temperature exported from described heat pipe.
According to the second aspect of the embodiment of the present invention, provide a kind of blood type analytical instrument, comprise the blending incubation device of the first aspect according to the embodiment of the present invention.
Be specifically described the present invention by specific embodiment below in conjunction with accompanying drawing, wherein identical or substantially identical parts adopt identical Reference numeral instruction.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the blending incubation device according to one embodiment of the invention;
Fig. 2 a and 2b is the schematic diagram of display according to the gas outlet outgassing direction of one embodiment of the invention;
Fig. 3 be gas pass through according to one embodiment of the invention blending incubation device time, temperature T changes to the change procedure schematic diagram that design temperature T establishes from room temperature T room;
Fig. 4 is the schematic diagram comprising the blending incubation device of mechnical oscillator according to one embodiment of the invention;
Fig. 5 is the schematic diagram comprising the blending incubation device of hertz oscilltor according to one embodiment of the invention;
Fig. 6 is the schematic diagram comprising the blending incubation device of ultrasonator according to one embodiment of the invention.
Embodiment
As shown in Figure 1, be the blending incubation device according to one embodiment of the invention, comprise: malleation source of the gas 100, gas outlet 102, and thermostat 104.After wherein malleation source of the gas 100 is started shooting, exportable permanent barotropic gas; Gas outlet 102 is communicated with described malleation source of the gas 100 by conduit 106, and thermostat 104 is arranged in the path between described malleation source of the gas 100 and described gas outlet 102, for controlling the temperature of the gas exported from described gas outlet, sees Fig. 1.
In one embodiment, gas outlet 102 is configured on the arc-shaped edges of reaction utensil 110 concave surface be in reaction utensil base band 108, outgassing direction is made to become predetermined angular along in reaction utensil 110 orientation with plane residing for reaction utensil 110 (namely reaction utensil base band 108 surface), such as 30-90 degree, such as 45 degree or about 45 degree again, as shown in the side view of Fig. 2 a and the vertical view of Fig. 2 b.Like this under the blowing of constant temperature gas, reagent in reaction utensil 110 and sample (such as blood sample) mixing material will rotate along the arc-shaped edges of reaction utensil, and from low-temperature condition, (reagent storage temperature is 2-8 DEG C, so blood sample is lower than room temperature after adding reagent (ratio is about 1:1)) under be increased to the temperature (such as about 37 DEG C) of setting fast, thus play the effect of mixing and constant-temperature incubation, fully react to make reagent and blood sample.When wherein gas is by blending incubation device according to the present embodiment, temperature T changes to change procedure that design temperature T establishes as shown in Figure 3 from room temperature T room.
In other embodiments, what such as will describe below comprises in the embodiment of oscillator, and described gas outlet 102 is configured to make outgassing direction perpendicular to plane residing for reaction utensil 110 and is in the middle part of reaction utensil 110.
In another embodiment, described blending incubation device also comprises filtrator 112 alternatively, and this filtrator 112 is arranged in the path between described malleation source of the gas 100 and described gas outlet 102, for filtering the gas from described malleation source of the gas 100.In one embodiment, described filtrator 112 is preferably arranged in the path between described malleation source of the gas 100 and described thermostat 104, as shown in Figure 1.
In one embodiment, described blending incubation device also comprises mechnical oscillator, and as shown in Figure 4, this mechnical oscillator comprises further: drive motor 114, cam 116, spring base 118, and vibrating mass 120.Its cam 116 connects with the output shaft of described drive motor 114; Spring base 118 is configured to be suitable for being fixed in frame, and one end of spring in spring base 118 is configured to be driven by described cam 116; Vibrating mass 120 is connected to the other end of the spring in described spring base 118, and is configured to contact with reaction utensil base band 108, such as, contact from the side of reaction utensil base band 108 with reaction utensil base band 108.Like this, when drive motor 114 works, band moving cam 116 rotates; Under the effect of cam 116, spring in spring base 118 can be compressed and discharge, thus the vibrating mass 120 being connected to the spring other end just can vibrate back and forth, reaction utensil base band 108 is applied repeatedly to knock (dynamics of knocking can according to actual needs by selecting the spring of the suitable coefficient of stiffiness to determine), and then the vibration realized the mixing material in the reaction utensil 110 in reaction utensil base band, its amplitude is equivalent to the difference of cam 116 height substantially, such as, can be set as about 1mm.
In one embodiment, described blending incubation device also comprises hertz oscilltor, and as shown in Figure 5, this hertz oscilltor comprises further: solenoid 122, spring 124, and vibrating mass 126.Wherein solenoid 122 can be configured to be suitable for being fixed in frame, and one end of spring 124 connects with solenoid 122, and the other end is connected with vibrating mass 126; The other end of vibrating mass 126 can be configured to contact with reaction utensil base band 108, such as, contact with the side of reaction utensil base band 108, and this vibrating mass 126 can be made with ferromagnetic material.Like this, when solenoid 122 does not power up, this hertz oscilltor remains static; When solenoid 122 powers up, will produce electromagnetic force, vibrating mass 126 moves to solenoid 122 under the effect of this electromagnetic force; When solenoid 122 power-off, vibrating mass 126 moves to reaction utensil base band 108 again under spring force.So along with powering up and power-off of solenoid 122, vibrating mass 126 just can vibrate back and forth under the repeated action of electromagnetic force and spring force, realizes reaction utensil base band 108 and then the vibration to the mixing material in the reaction utensil 110 on it.
In one embodiment, described blending incubation device also comprises ultrasonator, and as shown in Figure 6, this ultrasonator comprises further: electro coupled oscillator 128, transducer 130, and ultrasonic probe 132.Wherein electro coupled oscillator 128, transducer 130 and ultrasonic probe 132 connect successively.Electro coupled oscillator 128 produces electromagnetic oscillation, this electromagnetic oscillation is converted to ultrasound wave by transducer 130, and give coupled ultrasonic probe 132 by this ultrasonic transmission, ultrasonic probe 132 is configured to be positioned near reaction utensil base band 108, such as relative with the reaction utensil 110 in reaction utensil base band 108 side.So the ultrasound wave that ultrasonic probe 132 sends can be transferred to the mixing material in reaction utensil 110, realize the ultrasonic vibration to the mixing material in reaction utensil 110.
Thermostat 104 is temperature control equipments, and in one embodiment, it is made up of well heater, temperature sensor and heat pipe (such as metal tube, preferably copper pipe).Heat pipe is used for by the gas from described malleation source of the gas, and well heater is positioned at for heating described heat pipe near described heat pipe, and temperature sensor is for sensing the gas temperature exported from described heat pipe.Gas flows through in heat pipe, and the outside of heat pipe is heated by well heater, can be controlled the temperature of gas in gas outlet like this by temperature sensor.
Can be implemented in various analytical test equipment according to the blending incubation device of the embodiment of the present invention, such as, include but not limited to blood type analytical instrument, this is easily realize to those skilled in the art, is not described in detail at this.
Described the present invention by specific embodiment above, but the present invention is not limited to these specific embodiments.It will be understood by those skilled in the art that and can also make various amendment, equivalent replacement, change etc. to the present invention.But, as long as these conversion do not deviate from spirit of the present invention, all should within protection scope of the present invention.In addition, some terms that present specification and claims use not are restriction, are only used to be convenient to describe.In addition, " embodiment ", " another embodiment " etc. described in above many places represent different embodiments, can certainly by its all or part of realization in one embodiment.
Claims (8)
1. a blending incubation device, comprising:
Malleation source of the gas; And
Gas outlet, is communicated with described malleation source of the gas by conduit;
It is characterized in that, also comprise:
Thermostat, is arranged in the path between described malleation source of the gas and described gas outlet, for controlling the temperature of the gas that described gas outlet exports,
Wherein, described gas outlet is configured on the arc-shaped edges of the reaction utensil concave surface being in blending incubation device, and make outgassing direction become predetermined angular along on the linear array direction of described reaction utensil with plane residing for reaction utensil, to promote the liquid in rotation in described reaction utensil.
2. blending incubation device as claimed in claim 1, is characterized in that, also comprise:
Filtrator, is arranged in the path between described malleation source of the gas and described gas outlet, for filtering the gas from described malleation source of the gas.
3. blending incubation device as claimed in claim 2, is characterized in that: described filtrator is arranged in the path between described malleation source of the gas and described thermostat.
4. blending incubation device as claimed in claim 1, it is characterized in that, also comprise mechnical oscillator, this mechnical oscillator comprises further:
Drive motor;
Cam, connects with the output shaft of described drive motor;
Spring base, one end of spring wherein is configured to by described actuated by cams; And
Vibrating mass, is connected to the other end of the spring in described spring base, and is configured to contact with reaction utensil base band.
5. blending incubation device as claimed in claim 1, it is characterized in that, also comprise hertz oscilltor, this hertz oscilltor comprises further:
Solenoid;
Spring, one end connects with described solenoid; And
Vibrating mass, is connected to the other end of described spring, and is configured to contact with reaction utensil base band.
6. blending incubation device as claimed in claim 1, it is characterized in that, also comprise ultrasonator, this ultrasonator comprises further:
Electro coupled oscillator;
Transducer, connects with described electro coupled oscillator; And
Ultrasonic probe, connects with described transducer, and is configured to be positioned at reaction utensil near baseband.
7. the blending incubation device as described in any one of claim 1 to 6, is characterized in that, described thermostat comprises further:
Heat pipe, for passing through the gas from described malleation source of the gas;
Well heater, is positioned near described heat pipe, for heating described heat pipe; And
Temperature sensor, for sensing the gas temperature exported from described heat pipe.
8. a blood type analytical instrument, is characterized in that: comprise the blending incubation device described in any one of claim 1 to 7.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010507038.XA CN102445553B (en) | 2010-09-30 | 2010-09-30 | Blending incubation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010507038.XA CN102445553B (en) | 2010-09-30 | 2010-09-30 | Blending incubation device |
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| CN102445553A CN102445553A (en) | 2012-05-09 |
| CN102445553B true CN102445553B (en) | 2015-07-29 |
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| CN201010507038.XA Active CN102445553B (en) | 2010-09-30 | 2010-09-30 | Blending incubation device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102943041B (en) * | 2012-11-21 | 2014-11-12 | 陈子怡 | Oxygen continuously filling cell and tissue hatching device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2923717Y (en) * | 2005-07-21 | 2007-07-18 | 高春平 | Immune magnetically-activated-cell automatic separating device |
| CN201134741Y (en) * | 2007-12-24 | 2008-10-15 | 杜纪高 | High frequency vibrator |
| CN201583539U (en) * | 2009-12-23 | 2010-09-15 | 上海裕隆生物科技有限公司 | Vibration reactor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06186235A (en) * | 1992-12-18 | 1994-07-08 | Olympus Optical Co Ltd | Agitation device |
| DE112010005273B4 (en) * | 2009-02-27 | 2014-01-16 | Hitachi High-Technologies Corporation | Chemical analyzer |
| CN201382950Y (en) * | 2009-04-17 | 2010-01-13 | 武汉医尔特科技有限公司 | Air blast mixing device for novel full-automatic blood analyzer |
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2010
- 2010-09-30 CN CN201010507038.XA patent/CN102445553B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2923717Y (en) * | 2005-07-21 | 2007-07-18 | 高春平 | Immune magnetically-activated-cell automatic separating device |
| CN201134741Y (en) * | 2007-12-24 | 2008-10-15 | 杜纪高 | High frequency vibrator |
| CN201583539U (en) * | 2009-12-23 | 2010-09-15 | 上海裕隆生物科技有限公司 | Vibration reactor |
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| CN102445553A (en) | 2012-05-09 |
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Address after: 519031 office 2320, No. 3000, Huandao East Road, Hengqin new area, Zhuhai, Guangdong Patentee after: Yangpu Medical Technology Co.,Ltd. Address before: 510530 No.102, Kaiyuan Avenue, Science City, Guangzhou Economic and Technological Development Zone, Guangdong Province Patentee before: GUANGZHOU IMPROVE MEDICAL TECHNOLOGY Co.,Ltd. |
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