CN102445553A - Blending incubation device - Google Patents
Blending incubation device Download PDFInfo
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- CN102445553A CN102445553A CN201010507038XA CN201010507038A CN102445553A CN 102445553 A CN102445553 A CN 102445553A CN 201010507038X A CN201010507038X A CN 201010507038XA CN 201010507038 A CN201010507038 A CN 201010507038A CN 102445553 A CN102445553 A CN 102445553A
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- gas
- mixing
- reaction utensil
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- gas outlet
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Abstract
The invention discloses a blending incubation device, which comprises a positive-pressure gas source and an air outlet which is communicated with the positive-pressure gas source through a conduit. Moreover, the blending incubation device also comprises a thermostat which is arranged in an access between the positive-pressure gas source and the gas outlet and is used for controlling the temperature of gas output from the gas outlet. According to the blending incubation device disclosed by the embodiment of the invention, the reaction efficiency and the reaction speed of a reagent and a specimen can be effectively improved.
Description
Technical field
The present invention relates to a kind of mixing and hatch device, particularly relate to a kind of mixing that is used for analytical test and hatch device.
Background technology
In the various analytical tests that for example blood group is analyzed, fully whether reagent and sample (for example blood sample) result of reaction pair analysis (for example blood group analysis) play an important role, and fully whether reaction is relevant with its mixability and temperature and reagent is with sample.Because the storage temperature of reagent generally is at 2 ℃-8 ℃, thus the temperature comparison end when reagent mixes with the sample of for example blood sample and also condensation can appear sometimes.
With the full-automatic blood type analytical instrument is example, has only evenly mixing device at present and it is not carried out constant temperature and handle, and only through environment temperature it is hatched.Cause the concrete many shortcomings of existing blood type analytical instrument thus, for example the reaction time long, and possibly produce condensation.
Therefore, need and a kind ofly can improve reagent and reaction efficiency and reaction velocity, can effectively shorten the mixing in reaction time and hatch device such as the sample of blood sample.
Summary of the invention
The objective of the invention is in order to overcome the defective that prior art exists, provide a kind of and can improve reagent and hatch device such as the reaction efficiency of the sample of blood sample and the mixing of reaction velocity.In order to realize this purpose, the technical scheme that the present invention taked is following.
According to the first aspect of the embodiment of the invention, provide a kind of mixing to hatch device, comprising: the malleation source of the gas; And the gas outlet, be communicated with said malleation source of the gas through conduit; In addition, also comprise thermostat, be arranged in the path between said malleation source of the gas and the said gas outlet, be used to control the temperature of the gas of exporting said gas outlet.
In one embodiment, said mixing is hatched device and is also comprised filtrator, is arranged in the path between said malleation source of the gas and the said gas outlet, is used for the gas from said malleation source of the gas is filtered.In one embodiment, preferably, said filtrator is arranged in the path between said malleation source of the gas and the said thermostat.
In one embodiment, said mixing is hatched device and is also comprised mechnical oscillator, and this mechnical oscillator further comprises: drive motor; Cam connects with the output shaft of said drive motor; Spring base, an end of spring wherein are configured to driven by said cam; And vibrating mass, be connected the other end of the spring in the said spring base, and be configured to and can contact with the reaction utensil base band.
In one embodiment, said mixing is hatched device and is also comprised hertz oscilltor, and this hertz oscilltor further comprises: solenoid; Spring, an end and said solenoid join; And vibrating mass, be connected the other end of said spring, and be configured to and can contact with the reaction utensil base band.
In one embodiment, said mixing is hatched device and is also comprised ultrasonator, and this ultrasonator further comprises: electro coupled oscillator; Transducer joins with said electro coupled oscillator; And ultrasonic probe, join with said transducer, and be configured to can be positioned near the reaction utensil base band.
In one embodiment, preferably, said gas outlet is configured to be on the circular arc limit of reaction utensil concave surface, and makes outgassing direction along becoming predetermined angular with reaction utensil plane of living in the reaction utensil orientation.
In one embodiment, further preferably, said gas outlet is configured to make outgassing direction perpendicular to reaction utensil plane of living in and be in reaction utensil middle part.
In one embodiment, said thermostat further comprises: heat pipe; Be used for through gas from said malleation source of the gas; Well heater is positioned near the said heat pipe, is used for said heat pipe is heated; And temperature sensor, be used for the gas temperature of sensing from said heat pipe output.
According to the second aspect of the embodiment of the invention, a kind of blood type analytical instrument is provided, comprise according to the mixing of the first aspect of the embodiment of the invention and hatch device.
To combine accompanying drawing below and the present invention specified the Reference numeral indication that wherein identical or essentially identical parts employing is identical through concrete embodiment.
Description of drawings
Fig. 1 is the schematic diagram of hatching device according to the mixing of one embodiment of the invention;
Fig. 2 a and 2b are the synoptic diagram that shows according to the gas outlet outgassing direction of one embodiment of the invention;
Fig. 3 is a gas when hatching device according to the mixing of one embodiment of the invention, and temperature T changes to the change procedure synoptic diagram that design temperature T establishes from room temperature T chamber;
Fig. 4 is hatched schematic representation of apparatus according to the mixing that comprises mechnical oscillator of one embodiment of the invention;
Fig. 5 is hatched schematic representation of apparatus according to the mixing that comprises hertz oscilltor of one embodiment of the invention;
Fig. 6 is hatched schematic representation of apparatus according to the mixing that comprises ultrasonator of one embodiment of the invention.
Embodiment
As shown in Figure 1, be to hatch device according to the mixing of one embodiment of the invention, comprising: malleation source of the gas 100, gas outlet 102, and thermostat 104.After wherein malleation source of the gas 100 is started shooting, exportable permanent barotropic gas; Gas outlet 102 is communicated with said malleation source of the gas 100 through conduit 106, and thermostat 104 is arranged in the path between said malleation source of the gas 100 and the said gas outlet 102, is used to control the temperature from the gas of said gas outlet output, sees Fig. 1.
In one embodiment; Gas outlet 102 is configured to be on the circular arc limit of reaction utensil 110 concave surfaces on the reaction utensil base band 108; Make outgassing direction along becoming predetermined angular with reaction utensil 110 planes of living in (reaction utensil base band 108 surfaces just) in reaction utensil 110 orientations; 30-90 degree for example is more for example about 45 degree or 45 degree, shown in the vertical view of the side view of Fig. 2 a and Fig. 2 b.Like this under the blowing of constant temperature gas; Reagent and sample (for example blood sample) mixing material in the reaction utensil 110 will rotate along the circular arc limit of reaction utensil; And (the reagent storage temperature is 2-8 ℃ from low-temperature condition; So it is lower than room temperature that the blood sample sample adds reagent (ratio is about 1:1) back) under be increased to the temperature (for example about 37 ℃) of setting fast, thereby play the effect that mixing and constant temperature are hatched so that reagent and blood sample sample fully react.Wherein gas is when hatching device according to the mixing of present embodiment, and temperature T changes to the change procedure that design temperature T establishes from room temperature T chamber as shown in Figure 3.
In other embodiments, among the embodiment that comprises oscillator that will describe below for example, said gas outlet 102 is configured to make outgassing direction perpendicular to reaction utensil 110 planes of living in and be in reaction utensil 110 middle parts.
In another embodiment, said mixing is hatched device and is also comprised filtrator 112 alternatively, and this filtrator 112 is arranged in the path between said malleation source of the gas 100 and the said gas outlet 102, is used for the gas from said malleation source of the gas 100 is filtered.In one embodiment, said filtrator 112 preferably is arranged in the path between said malleation source of the gas 100 and the said thermostat 104, and is as shown in Figure 1.
In one embodiment, said mixing is hatched device and also comprised mechnical oscillator, and is as shown in Figure 4, and this mechnical oscillator further comprises: drive motor 114, cam 116, spring base 118, and vibrating mass 120.Its cam 116 connects with the output shaft of said drive motor 114; Spring base 118 is configured to be suitable for being fixed on the frame, and an end of the spring in the spring base 118 is configured to driven by said cam 116; Vibrating mass 120 is connected the other end of the spring in the said spring base 118, and is configured to and can contacts with reaction utensil base band 108, and for example the side from reaction utensil base band 108 contacts with reaction utensil base band 108.Like this, when drive motor 114 work, drive cam 116 and rotate; Under the effect of cam 116; Spring in the spring base 118 can be compressed and discharge; Thereby the vibrating mass 120 that is connected the spring other end just can vibrate back and forth, reaction utensil base band 108 is applied repeatedly knock (dynamics of knocking can be confirmed through the spring of selecting the suitable coefficient of stiffiness according to actual needs), and then realizes the vibration to the mixing material in the reaction utensil on the reaction utensil base band 110; Its amplitude is equivalent to the poor of cam 116 heights basically, for example can be set at about 1mm.
In one embodiment, said mixing is hatched device and also comprised hertz oscilltor, and is as shown in Figure 5, and this hertz oscilltor further comprises: solenoid 122, spring 124, and vibrating mass 126.Wherein solenoid 122 configurable one-tenth are suitable for being fixed on the frame, and an end and the solenoid 122 of spring 124 join, and the other end is connected with vibrating mass 126; The configurable one-tenth of the other end of vibrating mass 126 contacts with reaction utensil base band 108, for example contacts with a side of reaction utensil base band 108, and this vibrating mass 126 can be processed with ferromagnetic material.Like this, when solenoid 122 did not power up, this hertz oscilltor remained static; When solenoid 122 powers up, will produce electromagnetic force, vibrating mass 126 moves to solenoid 122 under the effect of this electromagnetic force; When solenoid 122 outages, vibrating mass 126 moves to reaction utensil base band 108 again under the effect of spring force.So along with the powering up and cut off the power supply of solenoid 122, vibrating mass 126 just can vibrate under the effect repeatedly of electromagnetic force and spring force back and forth, realize to reaction utensil base band 108 and then to the vibration of the mixing material in the reaction utensil on it 110.
In one embodiment, said mixing is hatched device and also comprised ultrasonator, and is as shown in Figure 6, and this ultrasonator further comprises: electro coupled oscillator 128, transducer 130, and ultrasonic probe 132.Wherein electro coupled oscillator 128, transducer 130 and ultrasonic probe 132 join successively.Electro coupled oscillator 128 produces electromagnetic oscillation; Transducer 130 converts this electromagnetic oscillation into ultrasound wave; And give coupled ultrasonic probe 132 with this ultrasonic transmission; Ultrasonic probe 132 is configured to be positioned near the reaction utensil base band 108, for example with reaction utensil base band 108 on the relative side of reaction utensil 110.So the ultrasound wave that ultrasonic probe 132 sends can be transferred to the mixing material in the reaction utensil 110, realize ultrasonic vibration to the mixing material in the reaction utensil 110.
Thermostat 104 is temperature control equipments, and in one embodiment, it is made up of well heater, temperature sensor and heat pipe (for example metal tube, preferably copper pipe).Heat pipe is used for through the gas from said malleation source of the gas, and well heater is used for said heat pipe is heated near being positioned at said heat pipe, and temperature sensor is used for the gas temperature of sensing from said heat pipe output.Gas flows through in heat pipe, and the temperature of gas in the gas outlet can be controlled like this by heater heats in the outside of heat pipe through temperature sensor.
Hatch device according to the mixing of the embodiment of the invention and can be implemented in the various analytical test equipment, for example include but not limited to blood type analytical instrument, this is to realize easily to those skilled in the art, does not do detailed description at this.
More than describe the present invention through concrete embodiment, but the present invention is not limited to these concrete embodiment.It will be understood by those skilled in the art that and to make various modifications to the present invention, be equal to replacement, change or the like.But these conversion all should be within protection scope of the present invention as long as do not deviate from spirit of the present invention.In addition, the more employed terms of present specification and claims are not restriction, only are for the ease of describing.In addition, above many places described " embodiment ", " another embodiment " or the like represent various embodiment, can certainly be with its all or part of being implemented among the embodiment.
Claims (10)
1. a mixing is hatched device, comprising:
The malleation source of the gas; And
The gas outlet is communicated with said malleation source of the gas through conduit;
It is characterized in that, also comprise:
Thermostat is arranged in the path between said malleation source of the gas and the said gas outlet, is used to control the temperature of the gas of exporting said gas outlet.
2. mixing as claimed in claim 1 is hatched device, it is characterized in that, also comprises:
Filtrator is arranged in the path between said malleation source of the gas and the said gas outlet, is used for the gas from said malleation source of the gas is filtered.
3. mixing as claimed in claim 2 is hatched device, it is characterized in that: said filtrator is arranged in the path between said malleation source of the gas and the said thermostat.
4. mixing as claimed in claim 1 is hatched device, it is characterized in that, also comprises mechnical oscillator, and this mechnical oscillator further comprises:
Drive motor;
Cam connects with the output shaft of said drive motor;
Spring base, an end of spring wherein are configured to driven by said cam; And
Vibrating mass is connected the other end of the spring in the said spring base, and is configured to and can contacts with the reaction utensil base band.
5. mixing as claimed in claim 1 is hatched device, it is characterized in that, also comprises hertz oscilltor, and this hertz oscilltor further comprises:
Solenoid;
Spring, an end and said solenoid join; And
Vibrating mass is connected the other end of said spring, and is configured to and can contacts with the reaction utensil base band.
6. mixing as claimed in claim 1 is hatched device, it is characterized in that, also comprises ultrasonator, and this ultrasonator further comprises:
Electro coupled oscillator;
Transducer joins with said electro coupled oscillator; And
Ultrasonic probe joins with said transducer, and is configured to can be positioned near the reaction utensil base band.
7. hatch device like each described mixing of claim 1 to 6, it is characterized in that: said gas outlet is configured to be on the circular arc limit of reaction utensil concave surface, and makes outgassing direction along becoming predetermined angular with reaction utensil plane of living in the reaction utensil orientation.
8. hatch device like each described mixing of claim 1 to 6, it is held to levy and is: said gas outlet is configured to make outgassing direction perpendicular to reaction utensil plane of living in and be in reaction utensil middle part.
9. hatch device like each described mixing of claim 1 to 6, it is characterized in that said thermostat further comprises:
Heat pipe is used for through the gas from said malleation source of the gas;
Well heater is positioned near the said heat pipe, is used for said heat pipe is heated; And
Temperature sensor is used for the gas temperature of sensing from said heat pipe output.
10. blood type analytical instrument is characterized in that: comprise that each described mixing of claim 1 to 9 hatches device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010507038.XA CN102445553B (en) | 2010-09-30 | 2010-09-30 | Blending incubation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010507038.XA CN102445553B (en) | 2010-09-30 | 2010-09-30 | Blending incubation device |
Publications (2)
| Publication Number | Publication Date |
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| CN102445553A true CN102445553A (en) | 2012-05-09 |
| CN102445553B CN102445553B (en) | 2015-07-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010507038.XA Active CN102445553B (en) | 2010-09-30 | 2010-09-30 | Blending incubation device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102943041A (en) * | 2012-11-21 | 2013-02-27 | 陈子怡 | Oxygen continuously filling cell and tissue hatching device |
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| JPH06186235A (en) * | 1992-12-18 | 1994-07-08 | Olympus Optical Co Ltd | Agitation device |
| CN2923717Y (en) * | 2005-07-21 | 2007-07-18 | 高春平 | Immune magnetically-activated-cell automatic separating device |
| CN201134741Y (en) * | 2007-12-24 | 2008-10-15 | 杜纪高 | High frequency vibrator |
| CN201382950Y (en) * | 2009-04-17 | 2010-01-13 | 武汉医尔特科技有限公司 | Air blast mixing device for novel full-automatic blood analyzer |
| WO2010098053A1 (en) * | 2009-02-27 | 2010-09-02 | 株式会社 日立ハイテクノロジーズ | Chemical analysis device |
| CN201583539U (en) * | 2009-12-23 | 2010-09-15 | 上海裕隆生物科技有限公司 | Vibration reactor |
-
2010
- 2010-09-30 CN CN201010507038.XA patent/CN102445553B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06186235A (en) * | 1992-12-18 | 1994-07-08 | Olympus Optical Co Ltd | Agitation device |
| CN2923717Y (en) * | 2005-07-21 | 2007-07-18 | 高春平 | Immune magnetically-activated-cell automatic separating device |
| CN201134741Y (en) * | 2007-12-24 | 2008-10-15 | 杜纪高 | High frequency vibrator |
| WO2010098053A1 (en) * | 2009-02-27 | 2010-09-02 | 株式会社 日立ハイテクノロジーズ | Chemical analysis device |
| CN201382950Y (en) * | 2009-04-17 | 2010-01-13 | 武汉医尔特科技有限公司 | Air blast mixing device for novel full-automatic blood analyzer |
| CN201583539U (en) * | 2009-12-23 | 2010-09-15 | 上海裕隆生物科技有限公司 | Vibration reactor |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102943041A (en) * | 2012-11-21 | 2013-02-27 | 陈子怡 | Oxygen continuously filling cell and tissue hatching device |
| CN102943041B (en) * | 2012-11-21 | 2014-11-12 | 陈子怡 | Oxygen continuously filling cell and tissue hatching device |
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| Publication number | Publication date |
|---|---|
| CN102445553B (en) | 2015-07-29 |
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Address after: 519031 office 2320, No. 3000, Huandao East Road, Hengqin new area, Zhuhai, Guangdong Patentee after: Yangpu Medical Technology Co.,Ltd. Address before: 510530 No.102, Kaiyuan Avenue, Science City, Guangzhou Economic and Technological Development Zone, Guangdong Province Patentee before: GUANGZHOU IMPROVE MEDICAL TECHNOLOGY Co.,Ltd. |