CN102441116B - Traditional Chinese medicinal preparation for treating narcolepsy - Google Patents
Traditional Chinese medicinal preparation for treating narcolepsy Download PDFInfo
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- CN102441116B CN102441116B CN201110390706.XA CN201110390706A CN102441116B CN 102441116 B CN102441116 B CN 102441116B CN 201110390706 A CN201110390706 A CN 201110390706A CN 102441116 B CN102441116 B CN 102441116B
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- traditional chinese
- chinese medicinal
- medicinal preparation
- narcolepsy
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- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 201000003631 narcolepsy Diseases 0.000 title claims abstract description 14
- 241001522129 Pinellia Species 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 239000003814 drug Substances 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 238000010410 dusting Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 10
- 210000000952 spleen Anatomy 0.000 abstract description 4
- 230000001939 inductive effect Effects 0.000 abstract description 3
- 238000011084 recovery Methods 0.000 abstract description 2
- 241000132012 Atractylodes Species 0.000 abstract 1
- 241000207925 Leonurus Species 0.000 abstract 1
- 206010041349 Somnolence Diseases 0.000 description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 206010062717 Increased upper airway secretion Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000026435 phlegm Diseases 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 4
- 239000006187 pill Substances 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 2
- 208000032140 Sleepiness Diseases 0.000 description 2
- 230000001914 calming effect Effects 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 208000037920 primary disease Diseases 0.000 description 2
- 230000037321 sleepiness Effects 0.000 description 2
- 235000015096 spirit Nutrition 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000002618 waking effect Effects 0.000 description 2
- 206010063659 Aversion Diseases 0.000 description 1
- 208000019914 Mental Fatigue Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- ZRHANBBTXQZFSP-UHFFFAOYSA-M potassium;4-amino-3,5,6-trichloropyridine-2-carboxylate Chemical compound [K+].NC1=C(Cl)C(Cl)=NC(C([O-])=O)=C1Cl ZRHANBBTXQZFSP-UHFFFAOYSA-M 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000009666 routine test Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Abstract
The invention belongs to the field of traditional Chinese preparations and relates to a traditional Chinese medicinal preparation for treating narcolepsy. The traditional Chinese medicinal preparation is prepared from the following raw materials in part by weight: 3 parts of rhizoma gastrodiae, 3 parts of rhizoma acori graminei, 2 parts of pinellia ternate, 3 parts of leonurus and 2 parts of white atractylodes rhizome. The traditional Chinese medicinal preparation has the effects of tonifying spleen and overcoming dampness, and inducing resuscitation and enlightening. When being used for treating the narcolepsy, the traditional Chinese medicinal preparation has the characteristics of clear treatment effect, quick effect, short treatment period, high recovery rate, uneasiness in relapse, safety and convenience.
Description
Technical field
The invention belongs to field of traditional Chinese, particularly a kind of Chinese medicine preparation for the treatment of narcolepsy.
Background technology
Modern medicine thinks that the cause of disease of primary disease is still not clear, patient when awakening generally in often and the vigilant level of fluctuation low under, afternoon is particularly evident, while increasing, there is microsleep in drowsiness degree, most patients first feel that when showing effect sleepiness increases the weight of and once made great efforts resistance, and only a few patients precepitates into sleep from relative waking state.The traditional Chinese medical science thinks that primary disease belongs to " disorders of excessive sleepiness " category, performance day and night, sleepy constantly, that exhales can wake up, sleep again after awake; Its pathogenesis is mainly due to overabundant YIN leading to insufficient YANG, because of sun initiatively, cloudy main quiet, therefore excess of YIN is drowsirness.Clinical middle tcm treatment according to syndrome differentiation has taked spleen invigorating victory method wet, consciousness and resuscitation restoring to treat this disease, has obtained good therapeutic effect.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine preparation for the treatment of narcolepsy, has advantages of determined curative effect, instant effect, short treating period, high, the difficult recurrence of cure rate.
A kind of Chinese medicine preparation for the treatment of narcolepsy of the present invention, is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 2 parts of 3 parts, Rhizoma Gastrodiae, 3 parts of Rhizoma Acori Graminei, 2 parts of the Rhizoma Pinelliaes, 3 parts of Herba Leonuris and the Rhizoma Atractylodis Macrocephalaes.
The present invention can make acceptable various preparations on Chinese materia medica, preferably pill.
Preparation method: by medicine-feeding concoct qualified, weigh and assort, roll altogether for fine powder, cross 80 order dusting covers, with cold boiled water by upper medicated powder general be piller, dry or cold drying, pack 10 grams every bag.
Usage and consumption: oral, once a bag, day takes three times, within 20 days, is a course for the treatment of.
Drug action mechanism of the present invention is as follows:
Rhizoma Gastrodiae: endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral, this product function endogenous wind stopping relieving convulsion and Gan Run are not strong, act on gentlely, are the good medicine of disturbing on treatment wind-phlegm.
Rhizoma Acori Graminei: resuscitation inducing and mind tranquilizing, removing dampness to restore normal function of the stomach, this product is pungent to be opened bitter dry, warm leading to, and fragrance is walked to alter, and not only has the mind calming of having one's ideas straightened out, the merit of calming the nerves and has removing dampness, eliminating phlegm, happy key, the merit turbid, refreshment intelligence of drying concurrently.
The Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, externally used detumescence pain relieving, the pungent temperature of this product and dry, is the key medicine of drying dampness to eliminate phlegm, warming for resolving cold-phlegm.
Herba Leonuri: promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing.
The Rhizoma Atractylodis Macrocephalae: air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive, this product is usually used in the diseases such as deficiency of spleen-QI and stomach-QI, distension and fullness in the abdomen, the soft Mental fatigue of limb.
Curative effect judgement:
Recovery from illness: symptom all disappears, in high spirits.
Take a turn for the better: cardinal symptom disappears substantially, random thoughts are dizzy unclear, sleepy.
Invalid: symptom is without improvement.
Therapeutic outcome: clinical treatment narcolepsy 95 examples, take pill of the present invention, once a bag, day takes three times, within 20 days, is a course for the treatment of.Take after the course for the treatment of, 81 examples of fully recovering, account for 85%, and 9 examples that take a turn for the better, account for 10%, and invalid 5 examples, account for 5%, total effective rate 95%.Shown in treatment, without any side effects to patient, three large routine tests and hepatic and renal function detect no abnormal.
Below enumerate several model cases:
Case 1: patient Wang, man, 44 years old, to suffer from more than narcolepsy half a year, heaviness of the head as if it were tightly bandaged, limbs are heavy, down in spirits, all day drowsiness lazy speech.Give Drug therapy of the present invention after the course for the treatment of, transference cure, spirit is straightforward, follows up a case by regular visits to not recurrence in a year.
Case 2: patient Zhang, man, 51 years old, it is sleepy, sleepy constantly that patient feels over one year all day, sleep about half an hour at every turn, the aftersensation fatigue and weak of waking up, spirit is not good enough, with dizzy symptom, examine as drowsirness disease, oral medicine of the present invention is after the course for the treatment of, and transference cure, follows up a case by regular visits to not recurrence in a year.
Case 3: patient Lee, female, 38 years old, lassitude, sleepy, aversion to cold and cold limbs, limbs were heavy, drowsiness round the clock constantly, examined as narcolepsy.Oral medicine of the present invention is after the course for the treatment of, and transference cure, follows up a case by regular visits to not recurrence in a year.
The present invention has the following advantages:
(1) invent selected medicine and all meet Pharmacopoeia of People's Republic of China regulation, according to compatibility, the present invention has that spleen invigorating victory is wet, the merit of consciousness and resuscitation restoring.
(2) the present invention can not only treat narcolepsy effectively, and can prevent the generation of this disease.
(3) the present invention knows card fortune method, and prescription is rigorous, scientific and efficient, and treatment narcolepsy instant effect, curative effect are high, safe ready.
The specific embodiment
Below in conjunction with embodiment, the present invention is described further.
Embodiment
Pill, takes raw material by weight: 2 parts of 3 parts, Rhizoma Gastrodiae, 3 parts of Rhizoma Acori Graminei, 2 parts of the Rhizoma Pinelliaes, 3 parts of Herba Leonuris and the Rhizoma Atractylodis Macrocephalaes.
Preparation method: by medicine-feeding concoct qualified, weigh and assort, roll altogether for fine powder, cross 80 order dusting covers, with cold boiled water by upper medicated powder general be piller, dry or cold drying, pack 10 grams every bag.
Claims (1)
1. treat a Chinese medicine preparation for narcolepsy, it is characterized in that being made by the raw material of following parts by weight: 2 parts of 3 parts, Rhizoma Gastrodiae, 3 parts of Rhizoma Acori Graminei, 2 parts of the Rhizoma Pinelliaes, 3 parts of Herba Leonuris and the Rhizoma Atractylodis Macrocephalaes; The preparation method of the Chinese medicine preparation of described treatment narcolepsy be by medicine-feeding concoct qualified, weigh and assort, roll altogether for fine powder, cross 80 order dusting covers, with cold boiled water by upper medicated powder general be piller, dry or cold drying, pack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110390706.XA CN102441116B (en) | 2011-11-30 | 2011-11-30 | Traditional Chinese medicinal preparation for treating narcolepsy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110390706.XA CN102441116B (en) | 2011-11-30 | 2011-11-30 | Traditional Chinese medicinal preparation for treating narcolepsy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102441116A CN102441116A (en) | 2012-05-09 |
| CN102441116B true CN102441116B (en) | 2014-01-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201110390706.XA Expired - Fee Related CN102441116B (en) | 2011-11-30 | 2011-11-30 | Traditional Chinese medicinal preparation for treating narcolepsy |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610921B (en) * | 2013-11-05 | 2016-04-06 | 李现峰 | A kind of Chinese medicine preparation for the treatment of type of deficiency of both the heart and spleen narcolepsy |
| CN104474422A (en) * | 2014-11-26 | 2015-04-01 | 青岛祥翔生物医药科技有限公司 | Traditional Chinese medicine for treating yang qi exhaustion type somnolency disease |
| CN105727122A (en) * | 2016-04-08 | 2016-07-06 | 李国玉 | Medicine composition for treating narcolepsy and preparing method thereof |
-
2011
- 2011-11-30 CN CN201110390706.XA patent/CN102441116B/en not_active Expired - Fee Related
Non-Patent Citations (8)
| Title |
|---|
| 中医药治疗发作性睡病的临床研究概况;张殿全等;《中医药学报》;20070220;第35卷(第01期);第51-52页 * |
| 发作性睡病的中医认识及治疗概况;王少杰等;《中医杂志》;20080417;第49卷(第04期);第369-371页 * |
| 夏如宁等.辨证治疗发作性睡病体会.《中国中医药信息杂志》.2002,第9卷(第08期),第58页. |
| 崔瑞林等.醒脾开窍汤治疗发作性睡病.《河南中医》.1999,第19卷(第02期),第41-42页. |
| 张殿全等.中医药治疗发作性睡病的临床研究概况.《中医药学报》.2007,第35卷(第01期),第51-52页. |
| 王少杰等.发作性睡病的中医认识及治疗概况.《中医杂志》.2008,第49卷(第04期),第369-371页. |
| 辨证治疗发作性睡病体会;夏如宁等;《中国中医药信息杂志》;20020815;第9卷(第08期);第58页 * |
| 醒脾开窍汤治疗发作性睡病;崔瑞林等;《河南中医》;19990420;第19卷(第02期);第41-42页 * |
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| Publication number | Publication date |
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| CN102441116A (en) | 2012-05-09 |
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Effective date of registration: 20180920 Address after: 226000 639 north outer ring road, Nantong, Jiangsu Patentee after: NANTONG BEICHENG SCIENCE & TECHNOLOGY ENTREPRENEURIAL MANAGEMENT CO., LTD. Address before: 226000 1 Jin Wang Road, Zha Xi industrial park, Gangzha District, Nantong, Jiangsu. Patentee before: Nantong King Adhesive Products Co., Ltd. |
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Granted publication date: 20140115 Termination date: 20191130 |
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