CN102440331A - Pig alfa interferon-contained feed additive - Google Patents
Pig alfa interferon-contained feed additive Download PDFInfo
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- CN102440331A CN102440331A CN2010105073852A CN201010507385A CN102440331A CN 102440331 A CN102440331 A CN 102440331A CN 2010105073852 A CN2010105073852 A CN 2010105073852A CN 201010507385 A CN201010507385 A CN 201010507385A CN 102440331 A CN102440331 A CN 102440331A
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Abstract
The invention relates to a pig alfa interferon-contained feed additive, which is prepared from mixing zymophyte, pine needle meal, black soil powder, vitamin B1, vitamin B2, vitamin E, leonurus powder, globin powder and pig alfa interferon powder. The additive has the broad spectrum antiviral function and the strong antiviral function, can be added into the feed for a long term, and is used for preventing the viral diseases. The additive plays a part in the body after entering along with the livestock and poultry feed, induces antiviral enzyme to be produced in the body, and plays the role of early prevention, simultaneously, also has the immune adjustment function, increases the immunities of the livestock and poultry and the nutrient substance of the feed, and improves the tastes of meat, egg and milk.
Description
Technical field
The present invention relates to a kind of feed addictive that is used for animal and fowl fodder, is a kind of feed addictive that contains porcine alpha-IFN and preparation method thereof specifically.
Background technology
Along with growth in the living standard, human increasing to the demand of food such as meat, egg, milk, also increasingly high to quality and nutritional requirement.
In order to satisfy the human animal products demand that enlarges day by day, the breeding way of livestock and poultry breeding industry from traditional extensive operation to high density, intensification high speed development.New breeding way is pursued delivering for sale or the speed of laying eggs of livestock and poultry owing to too pay attention to output, generally uses the feed that is added with various additives or even hormone to feed livestock and poultry.And this breeding way makes the animal products quality descend inevitably, and meat, egg, milk nutritional labeling disappearance, even cause harmful substance such as hormone residual have influenced human healthy.Simultaneously, be accompanied by high speed development expensive, intensive culture, the disease problem has inevitably formed maximum threat to the livestock and poultry industry, has caused serious economy loss to aquaculture, becomes the fast-developing big bottleneck of restriction livestock and poultry industry.
What breed endangered maximum to fowl poultry kind is infectious disease, and especially virosis accounts for 70% of disease total amount.Still lack the efficacious therapy means for the fowl poultry kind viral disease at present, the prevention and the treatment approach of fowl poultry kind infectious disease is mainly vaccine and chemical antiviral agent.But be prone to cause drug resistance after the prolonged and repeated use of most of chemical classes medicine, and cause the medicament residue in the animal body easily, bring negative effect to health.And traditional vaccine is because its high specific, can't keep out the new impact that the appearance of variation and the novel disease of virus brings to livestock and poultry breeding industry.
Porcine alpha-IFN is one type of glycoprotein that extensive BA is arranged, and is divided into 2 hypotypes, has 17 gene copies at least, is distributed in No. 1 chromosome of pig.Porcine alpha-IFN has multiple effects such as regulating human body immune function, antiviral, antitumor, antiproliferative.Use porcine alpha-IFN can reach antiviral effect through the adjusting to body immune system, do not have drug resistance and medicament residue risk, and have the antiviral activity of wide spectrum, therefore having received widely, the parent looks at.
Summary of the invention
The object of the present invention is to provide a kind of feed addictive that contains porcine alpha-IFN, to strengthen immunity of livestock, the nutrition that improves meat, egg, milk.
The present invention is by yeast powder, pine needle meal, black earth powder, Cobastab
1, Cobastab
2, vitamin E, motherwort powder, globulin powder and porcine alpha-IFN powder be that component is mixed and is made into, the weight ratio of its each component is:
0.6～1.0 part in porcine alpha-IFN powder
5～15 parts of globulin powders
5～15 parts of motherwort powders
5～10 parts of zymophytes
Cobastab
10.01～0.08 part
Cobastab
20.01～0.08 part
0.01～0.08 part of vitamin E
45～60 parts of pine needle meals
5～16 parts in black earth powder
The feed addictive parts by weight that the present invention contains porcine alpha-IFN are preferably:
0.8～0.9 part in porcine alpha-IFN powder
8～13 parts of globulin powders
8～13 parts of motherwort powders
6～8 parts of zymophytes
Cobastab
10.02～0.07 part
Cobastab
20.02～0.07 part
0.02～0.07 part of vitamin E
50～58 parts of pine needle meals
6～15 parts in black earth powder
Wherein, contain gemma bacterium, saccharomycete and lactic acid bacteria in the described zymophyte, its content separately does; Gemma bacterium 0.1～0.6 hundred million/gram, saccharomycete 0.01～0.06 hundred million/gram, lactic acid bacteria 0.01～0.06 hundred million/gram.
The invention has the beneficial effects as follows:
Contain the porcine alpha-IFN powder in the additive component of the present invention and have antiviral effect and immunoregulation effect, thereby make body be in best state of immune response, can stimulate the NK cell and strengthen its killing ability, help body and remove virus infections; Pine needle meal has rich nutrient substances and bioactivator, can promote growth of animals or poultry, improves the reproductive performance of animal, improves the animal product quality, strengthens the diseases prevention ability of animal; Contain multiple alkaloids such as stachydrine, motherwort pyridine, leonurinine in the motherwort of motherwort powder, and antenatal 1 month interpolation 2%-3% motherwort powder in feed of sow, can make sow milk in postpartum secretion increasing, weight gain of piglets is accelerated; Also contain globulin powder in the additive of the present invention in addition, it has abundant immune substance, and the content of immunoglobulin (Ig) is high; Also have a large amount of somatomedins, lysozyme etc.Can increase the palatability of feed; Improve piglet daily gain, feed intake and feed conversion rate, raising immunity; Effectively prevent the newborn animal disease; Reduce diarrhoea generation, reduce ablactation stress, can effectively replace other protein sources, also do not have side effect such as the residual and contaminated environment of harmful substances, so SDPP in the use safety with reliable.
Therefore additive of the present invention has the broad-spectrum disease resistance toxic action; And antivirus action is strong; Can be used as long-term precautionary measures, livestock and poultry only need can get in the body with the feed feed and play a role, in vivo the inducing anti-disease poison; Performance early prevention effect can be used for comprising the long-term control and the early treatment of the various viral diseases of bird flu.Also have powerful immunoregulation effect, can strengthen immunity of livestock, reinforced nutrition matter, the taste of raising meat, egg, milk.Additive of the present invention is easy to use, and is simple, and environmental protection.
The specific embodiment
Below in conjunction with embodiment the present invention is done further description, but said embodiment is not as to qualification of the present invention.
Embodiment 1:
Contain in every 100g feed addictive: zymophyte 7g, pine needle meal 57g, black earth powder 15g, Cobastab
10.07g, Cobastab
20.07g, vitamin E 0.06g, motherwort powder 10g, globulin powder 10g, porcine alpha-IFN powder 0.8g.Wherein, contain 0.3 hundred million of gemma bacterium/gram in the zymophyte, 0.05 hundred million/gram of saccharomycete, 0.05 hundred million/gram of lactic acid bacteria.Above material is pulverized in pulverizer, evenly mixed, promptly process feed addictive according to said weight.
Embodiment 2:
Feed addictive is to the influence of child care pig growth
In the basal diet of prescription pig as shown in table 1, add the feed addictive that the embodiment of the invention 1 provides.With 30 ages in days test piglet is research object, and 3 test group and 1 control group are established in test altogether, wherein add 0.1%, 0.3%, 0.5% the embodiment of the invention 1 porcine alpha-IFN feed addictive in the basal diet of test group pig respectively.In process of the test, will examine the influence of the additive of various dose to the growth of child care pig, concrete data see the following form 2:
The feed formula of table 1 basal diet and trophic level
The feed addictive of table 2 various dose is to the influence (body weight kilogram) of child care pig growth
Can know that by table 2 test the porcine alpha-IFN feed addictive that adds various dose all is higher than control group to the whole trend that is raising of child care pig growth.But the test group pig through relatively finding out the porcine alpha-IFN of interpolation 0.5% should be from feedstuff-meat ratio all than other two groups of test pig from rate of body weight gain.Therefore, the porcine alpha-IFN feed addictive can promote the growth of pig to a certain extent.
Embodiment 3:
Contain in every 100g feed addictive: zymophyte 6g, pine needle meal 54g, black earth powder 13g, Cobastab
10.05g, Cobastab
20.05g, vitamin E 0.05g, motherwort powder 13g, globulin powder 13g, porcine alpha-IFN powder 0.85g.Wherein, contain 0.3 hundred million of gemma bacterium/gram in the zymophyte, 0.05 hundred million/gram of saccharomycete, 0.05 hundred million/gram of lactic acid bacteria.Above material is pulverized in pulverizer, evenly mixed, promptly process feed addictive according to said weight.
Embodiment 4:
Contain in every 100g feed addictive: zymophyte 8g, pine needle meal 55g, black earth powder 12g, vitaminB10 .02g, vitamin B2 0.04g, vitamin E 0.04g, motherwort powder 12g, globulin powder 12g, porcine alpha-IFN powder 0.9g.Wherein, contain 0.3 hundred million of gemma bacterium/gram in the zymophyte, 0.05 hundred million/gram of saccharomycete, 0.05 hundred million/gram of lactic acid bacteria.Above material is pulverized in pulverizer, evenly mixed, promptly process feed addictive according to said weight.
Embodiment 5
Feed addictive is to the influence of pig production performance, and this application examples adds the feed addictive of embodiment 2.A control group and a test group are established in this test altogether, and control group does not add any additives, the feed addictive of the embodiment of the invention 2 porcine alpha-IFNs of test group interpolation 0.2%, sow omnidistance 0.2%.The experimental observation phase is 50 days.
Table 3 porcine alpha-IFN feed addictive uses the influence of back to the piglet production performance sow
Can know by table 3 test; Use the porcine alpha-IFN feed addictive in the nospecific immunity level that improves animal (especially piglet); Improve liver function; Improve immune relevant enzyme level and improve the specific immunity level of animal, strengthen the immune response of animal to vaccine, aspects such as raising antibody titer have a significant effect.As feed addictive, be considered to strengthen animal resist the disease power, keep body health, promote the effective means of growth.According to different growth phases of animal and health status, porcine alpha-IFN is evenly sneaked into the natural green feed that conventional feed just can be produced generation immunity behind the animal edible with corresponding ratio.
Claims (3)
1. a feed addictive that contains porcine alpha-IFN is characterized in that, said additive comprises zymophyte, pine needle meal, black earth powder, Cobastab
1, Cobastab
2, vitamin E, motherwort powder, globulin powder, porcine alpha-IFN powder, the parts by weight of its each component are:
0.6～1.0 part in porcine alpha-IFN powder
5～15 parts of globulin powders
5～15 parts of motherwort powders
5～10 parts of zymophytes
Cobastab
10.01～0.08 part
Cobastab
20.01～0.08 part
0.01～0.08 part of vitamin E
45～60 parts of pine needle meals
5～16 parts in black earth powder.
2. a kind of feed addictive that contains porcine alpha-IFN according to claim 1 is characterized in that the parts by weight of each component are:
0.8～0.9 part in porcine alpha-IFN powder
8～13 parts of globulin powders
6～13 parts of motherwort powders
6～8 parts of zymophytes
Cobastab
10.02～0.07 part
Cobastab
20.02～0.07 part
0.02～0.07 part of vitamin E
50～58 parts of pine needle meals
6～15 parts in black earth powder.
3. a kind of feed addictive that contains porcine alpha-IFN according to claim 1 and 2; It is characterized in that containing in the said zymophyte gemma bacterium, saccharomycete and lactic acid bacteria; Its content separately is: gemma bacterium 0.1～0.6 hundred million/gram; Saccharomycete 0.01～0.06 hundred million/gram, lactic acid bacteria 0.01～0.06 hundred million/gram.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105073852A CN102440331A (en) | 2010-10-15 | 2010-10-15 | Pig alfa interferon-contained feed additive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105073852A CN102440331A (en) | 2010-10-15 | 2010-10-15 | Pig alfa interferon-contained feed additive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102440331A true CN102440331A (en) | 2012-05-09 |
Family
ID=46003657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105073852A Pending CN102440331A (en) | 2010-10-15 | 2010-10-15 | Pig alfa interferon-contained feed additive |
Country Status (1)
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|---|---|
| CN (1) | CN102440331A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300247A (en) * | 2013-06-14 | 2013-09-18 | 广东旺大集团有限公司萝岗分公司 | Feed for weaned pigs and preparation method for feed |
| CN104872399A (en) * | 2014-02-28 | 2015-09-02 | 雨润慕德生物科技（连云港）有限公司 | Interferon livestock and poultry micro-ecology additive |
| CN107865216A (en) * | 2017-11-16 | 2018-04-03 | 广西壮族自治区畜牧研究所 | A kind of mulberry leaf biological feedstuff and its production and use |
-
2010
- 2010-10-15 CN CN2010105073852A patent/CN102440331A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300247A (en) * | 2013-06-14 | 2013-09-18 | 广东旺大集团有限公司萝岗分公司 | Feed for weaned pigs and preparation method for feed |
| CN104872399A (en) * | 2014-02-28 | 2015-09-02 | 雨润慕德生物科技（连云港）有限公司 | Interferon livestock and poultry micro-ecology additive |
| CN107865216A (en) * | 2017-11-16 | 2018-04-03 | 广西壮族自治区畜牧研究所 | A kind of mulberry leaf biological feedstuff and its production and use |
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Application publication date: 20120509 |