CN102423543A - Vinpocetine special-purpose crystallization pot - Google Patents
Vinpocetine special-purpose crystallization pot Download PDFInfo
- Publication number
- CN102423543A CN102423543A CN2011102579231A CN201110257923A CN102423543A CN 102423543 A CN102423543 A CN 102423543A CN 2011102579231 A CN2011102579231 A CN 2011102579231A CN 201110257923 A CN201110257923 A CN 201110257923A CN 102423543 A CN102423543 A CN 102423543A
- Authority
- CN
- China
- Prior art keywords
- vinpocetine
- pot
- special
- tank
- crystallizing tank
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The invention relates to a vinpocetine special-purpose crystallization pot, which contains a pot rack, a pot and a stirring device. The pot contains a pot body and a cover. The bottom of the pot body is provided with a discharge hatch which is equipped with a discharged valve. A feed inlet is disposed on the cover. The periphery of the pot body is provided with an insulation jacket with a steam inlet and a condensed water outlet. The crystallization pot also contains a condensation coil pipe disposed inside the pot body. The condensation coil pipe is equipped with a condensate liquid inlet and a condensate liquid outlet which extend out through the pot. According to the crystallization pot, the condensation coil pipe is arranged inside the pot. As the condensation coil pipe directly contacts with a material, the heat transfer efficiency is highest, and the material can be rapidly cooled. Therefore, the vinpocetine crystallization rate can be raised and the crystallization efficiency can be improved. In addition, the invention is simple to arrange and convenient to operate.
Description
Technical field
the present invention relates to the special-purpose crystallizing tank of a kind of vinpocetine.
Background technology
vinpocetine is the derivative of alkaloid pervone, and it is through helping aerobic glycolysis and promoting blood flow to show the activity to the neuron metabolism to the ischemic region reallocation.Report that in addition vinpocetine can increase the utilization of brain circulation and oxygen.Vinpocetine is generally used for helping improve memory, and can help antagonism senile dementia symptom.
are present, adopt the synthetic vinpocetine of chemical method, generally all need improve product purity through recrystallization.Recrystallization mainly is to select vinpocetine and all dissolvent solvent of impurity (being generally ethanol) through lowering the temperature, the vinpocetine crystallization to be separated out then dissolving crude product.Generally speaking, in order to reach whole dissolvings of bullion, generally to system be heated to 50 to 60 degrees centigrade, and, then will temperature be cooled to below 10 degrees centigrade for the vinpocetine crystallization is separated out.Above-mentioned crystallization is carried out in crystallizing tank usually.The chuck that the crystallizing tank that industry such as traditional dairy industry, food, chemical industry, beverage are used comprises a jar frame, is arranged on tank body, the agitating device on jar frame and is arranged on the tank body periphery; Wherein the bottom of tank body offers drain hole; Can the crystal of separating out be emitted; In the chuck or logical hot water or steam so that tank body is heated, or logical condensed water lowers the temperature to tank body, two functions can not and be used.When adopting such crystallizing tank to carry out the crystallization of vinpocetine; Following problem will appear: all dissolve in order to make the vinpocetine bullion, then must tank body be heated to requirement through logical heating steam of chuck or hot water, treat that the vinpocetine bullion is all after the dissolving; Can only rely on the nature cooling to lower the temperature to material in tank; Length consuming time, the crystallization rate variance, product yield is low.Suppose to use another container earlier the vinpocetine bullion all after the dissolving, to be transferred to solution the tank body of crystallizing tank again, be utilized in that logical cooling water reaches the needed low temperature of crystallization in the chuck; The former is high slightly though this method percent crystallization in massecuite is compared, and operation is trouble very, and in fact is the equal of to have used two complete equipments; Because in another container, will establish heater and agitating device in addition at least; In addition, adopt the chuck cooling, very slow to the cooling of material in tank; Percent crystallization in massecuite is not high, and efficient is also lower.
to sum up, needing badly provides vinpocetine special-purpose crystallizing tank, improves percent crystallization in massecuite and crystalline rate and reduces cost the purpose that simplifies the operation to reach.
Summary of the invention
technical problem to be solved by this invention is the deficiency that overcomes prior art, provides a kind of vinpocetine special-purpose crystallizing tank.
For solving the problems of the technologies described above, the present invention takes following technical scheme:
The special-purpose crystallizing tank of
a kind of vinpocetine; It comprises a jar frame, is arranged on tank body and agitating device on jar frame; Wherein tank body comprises can body and the cover that is tightly connected with can body, and the bottom of can body offers discharging opening, and is provided with baiting valve in the discharging opening position; Cover is provided with charging aperture; Also be provided with the insulation jacket with steam inlet and condensation-water drain in the can body periphery, described crystallizing tank also comprises the condenser coil that is arranged in the can body, and this condenser coil has condensate liquid inlet and the condensate outlet that stretches out the tank body setting.
preferably, condensate liquid inlet and condensate outlet lay respectively at the downside and the upside of can body.
preferably, the centerline direction of condenser coil is consistent with the short transverse of can body.
more preferably, the material of condenser coil is a titanium steel.
are according to further embodiment of the present invention: agitating device is a mechanical stirring device; It comprises fire-proof motor, decelerator, anchor agitator; And condenser coil is positioned at the periphery of anchor agitator, and simultaneously crystallizing tank also comprises the visor hand hole that is arranged on the cover, anti-riotly looks lamp and lead to the respirator in the tank body.
Because the enforcement of above technical scheme, the present invention compared with prior art has following advantage:
crystallizing tank of the present invention, it is provided with condenser coil in tank body, when adopting it to carry out the vinpocetine crystallization; Utilize chuck Nei Tongjia hot water or steam to heat tank body earlier, under the stirring of agitating device, make the vinpocetine dissolving crude product, behind whole vinpocetine dissolving crude products; In condenser coil, feeding condensed fluid cools off the material in the tank body; Because condenser coil directly contacts with material, this heat exchange efficiency is the highest, and material is able to by quick cooling; So, can improve the percent crystallization in massecuite and the raising crystalline rate of vinpocetine.In addition, the present invention is provided with simply, and is easy to operate.
Description of drawings
are done further detailed explanation below in conjunction with accompanying drawing and concrete embodiment to the present invention.
Fig. 1 looks sketch map for the master of the special-purpose crystallizing tank of vinpocetine of the present invention;
wherein: 1, jar frame; 2, tank body; 20, can body; 200, discharging opening; 21, cover; 210, charging aperture; 3, agitating device; 4, baiting valve; 5, insulation jacket; 50, steam inlet; 51, condensation-water drain; 6, condenser coil; 60, condensate liquid inlet; 61, condensate outlet; 7, visor hand hole; 8, the anti-riot lamp of looking; 9, respirator; 10, feed pipe.
The specific embodiment
are as shown in Figure 1, and according to the special-purpose crystallizing tank of a kind of vinpocetine of present embodiment, it comprises jar frame 1, is arranged on tank body 2 and agitating device 3 on jar frame 1; Wherein tank body 2 comprises can body 20 and the cover 21 that is tightly connected with can body 20, and the bottom of can body 20 offers discharging opening 200, and is provided with baiting valve 4 in discharging opening 200 positions; Cover 21 is provided with charging aperture 210; Be connected with feed pipe 10 in charging aperture 210 positions, can body 20 peripheries also are provided with the insulation jacket 5 with steam inlet 50 and condensation-water drain 51, and this crystallizing tank also comprises the condenser coil 6 that is arranged in the can body 20; This condenser coil 6 has the condensate liquid inlet 60 and condensate outlet 61 that stretches out tank body 2 settings; In addition, for the needs of reality, also on kettle cover 21, be provided with visor hand hole 7, explosion-proof lamp 8 and the respirator 9 etc. looked.
Downside and upside that condensate liquid inlet 60 that
are above-mentioned and condensate outlet 61 lay respectively at can body 20; The centerline direction of condenser coil 6 is consistent with the short transverse of can body 20; And the material of condenser coil 6 is a titanium steel, has excellent corrosion resisting performance, simultaneously; Agitating device 3 in the present embodiment is a mechanical stirring device; It comprises fire-proof motor 30, decelerator 31, anchor agitator 32, and condenser coil 6 is positioned at the periphery of anchor agitator, does not influence the operate as normal of agitator 32.
The special-purpose crystallizing tank of vinpocetine is set up condenser coil at tank body, when adopting it to carry out the vinpocetine crystallization in
present embodiment; Utilize chuck Nei Tongjia hot water or steam to heat tank body earlier, under the stirring of agitating device, make the vinpocetine dissolving crude product, behind whole vinpocetine dissolving crude products; In condenser coil, feeding condensed fluid cools off the material in the tank body; Because condenser coil directly contacts with material, this heat exchange efficiency is the highest, and material is able to by quick cooling; So, can improve the percent crystallization in massecuite and the raising crystalline rate of vinpocetine.In addition, the present invention is provided with simply, and is easy to operate.
More than the present invention has been done detailed description; Its purpose is to let the personage that is familiar with this art can understand content of the present invention and implements; Can not limit protection scope of the present invention with this; All equivalences of doing according to spirit of the present invention change or modify, and all should be encompassed in protection scope of the present invention
Claims (6)
1. the special-purpose crystallizing tank of a vinpocetine; It comprises a jar frame (1), is arranged on tank body (2) and agitating device (3) on the said jar of frame (1); Said tank body (2) comprises can body (20) and the cover (21) that is tightly connected with can body (20); The bottom of said can body (20) offers discharging opening (200); And be provided with baiting valve (4) in discharging opening (200) position, said cover (21) is provided with charging aperture (210), also is provided with the insulation jacket (5) with steam inlet (50) and condensation-water drain (51) in said can body (20) periphery; It is characterized in that: described crystallizing tank also comprises the condenser coil (6) that is arranged in the said can body (20), and described condenser coil (6) has condensate liquid inlet (60) and the condensate outlet (61) that stretches out said tank body (2) setting.
2. the special-purpose crystallizing tank of vinpocetine according to claim 1, it is characterized in that: described condensate liquid inlet (60) and condensate outlet (61) lay respectively at the downside and the upside of described can body (20).
3. the special-purpose crystallizing tank of vinpocetine according to claim 1, it is characterized in that: the centerline direction of described condenser coil (6) is consistent with the short transverse of described can body (20).
4. the special-purpose crystallizing tank of vinpocetine according to claim 1, it is characterized in that: the material of described condenser coil (6) is a titanium steel.
5. the special-purpose crystallizing tank of vinpocetine according to claim 1; It is characterized in that: described agitating device (3) is a mechanical stirring device; It comprises fire-proof motor (30), decelerator (31), anchor agitator (32), and described condenser coil (6) is positioned at the periphery of described anchor agitator (32).
6. the special-purpose crystallizing tank of vinpocetine according to claim 1 is characterized in that: described crystallizing tank also comprises the visor hand hole (7) that is arranged on the said cover (21), anti-riotly looks lamp (8) and lead to the respirator (9) in the said tank body (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102579231A CN102423543A (en) | 2011-09-02 | 2011-09-02 | Vinpocetine special-purpose crystallization pot |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102579231A CN102423543A (en) | 2011-09-02 | 2011-09-02 | Vinpocetine special-purpose crystallization pot |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102423543A true CN102423543A (en) | 2012-04-25 |
Family
ID=45957627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011102579231A Pending CN102423543A (en) | 2011-09-02 | 2011-09-02 | Vinpocetine special-purpose crystallization pot |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102423543A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106521039A (en) * | 2016-12-26 | 2017-03-22 | 广西崇左市湘桂糖业有限公司 | Molasses cooking device for sugar manufacturing |
| CN106807106A (en) * | 2015-11-30 | 2017-06-09 | 中美华世通生物医药科技（武汉）有限公司 | Crystal system and method for crystallising |
| CN106955501A (en) * | 2017-05-27 | 2017-07-18 | 湖北华丹医药科技股份有限公司 | A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device |
| CN108905268A (en) * | 2018-09-25 | 2018-11-30 | 江西中医药大学 | A kind of alternating temperature crystallization oil water separator and volatile oil extracting system |
| CN108905267A (en) * | 2018-09-25 | 2018-11-30 | 江西中医药大学 | A kind of volatile oil crystallization extraction system and essential oil production line |
| CN108940014A (en) * | 2018-07-27 | 2018-12-07 | 芜湖市黄山松工业地坪新材料有限公司 | A kind of thinning tank processed for building wear-resistant material |
| CN109589640A (en) * | 2018-11-23 | 2019-04-09 | 衡阳市晋宏精细化工有限公司 | The crystallizer of hot and cold water alternate functions is provided |
| CN113019177A (en) * | 2021-02-01 | 2021-06-25 | 李成娟 | Cosmetics stirring cooling device capable of automatically adding additives at proper temperature |
| CN113041643A (en) * | 2020-09-11 | 2021-06-29 | 禹城鼎盛天成生物科技有限公司 | Nervonic acid oil spin crystallization device and method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201399256Y (en) * | 2009-04-10 | 2010-02-10 | 江阴苏利科技有限公司 | Continual recrystallization solvent distilling device |
| CN202199158U (en) * | 2011-09-02 | 2012-04-25 | 江苏斯威森生物医药工程研究中心有限公司 | Special crystalizing tank for vinpocetine |
-
2011
- 2011-09-02 CN CN2011102579231A patent/CN102423543A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201399256Y (en) * | 2009-04-10 | 2010-02-10 | 江阴苏利科技有限公司 | Continual recrystallization solvent distilling device |
| CN202199158U (en) * | 2011-09-02 | 2012-04-25 | 江苏斯威森生物医药工程研究中心有限公司 | Special crystalizing tank for vinpocetine |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106807106A (en) * | 2015-11-30 | 2017-06-09 | 中美华世通生物医药科技（武汉）有限公司 | Crystal system and method for crystallising |
| CN106521039A (en) * | 2016-12-26 | 2017-03-22 | 广西崇左市湘桂糖业有限公司 | Molasses cooking device for sugar manufacturing |
| CN106955501A (en) * | 2017-05-27 | 2017-07-18 | 湖北华丹医药科技股份有限公司 | A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device |
| CN108940014A (en) * | 2018-07-27 | 2018-12-07 | 芜湖市黄山松工业地坪新材料有限公司 | A kind of thinning tank processed for building wear-resistant material |
| CN108905268A (en) * | 2018-09-25 | 2018-11-30 | 江西中医药大学 | A kind of alternating temperature crystallization oil water separator and volatile oil extracting system |
| CN108905267A (en) * | 2018-09-25 | 2018-11-30 | 江西中医药大学 | A kind of volatile oil crystallization extraction system and essential oil production line |
| CN108905268B (en) * | 2018-09-25 | 2023-09-22 | 江西中医药大学 | Variable-temperature crystallization oil-water separator and volatile oil extraction system |
| CN108905267B (en) * | 2018-09-25 | 2023-09-26 | 江西中医药大学 | Volatile oil crystallization extraction system and essential oil production line |
| CN109589640A (en) * | 2018-11-23 | 2019-04-09 | 衡阳市晋宏精细化工有限公司 | The crystallizer of hot and cold water alternate functions is provided |
| CN113041643A (en) * | 2020-09-11 | 2021-06-29 | 禹城鼎盛天成生物科技有限公司 | Nervonic acid oil spin crystallization device and method thereof |
| CN113041643B (en) * | 2020-09-11 | 2023-11-24 | 禹城鼎盛天成生物科技有限公司 | Nervonic acid grease spin crystallization device and method thereof |
| CN113019177A (en) * | 2021-02-01 | 2021-06-25 | 李成娟 | Cosmetics stirring cooling device capable of automatically adding additives at proper temperature |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102423543A (en) | Vinpocetine special-purpose crystallization pot | |
| CN202961948U (en) | Acrylamide crystallization equipment with multiple kettles connected in series | |
| CN202199158U (en) | Special crystalizing tank for vinpocetine | |
| CN203494209U (en) | Vacuum evaporative crystallization device of dihydroxy acetone aqueous solution | |
| CN109621478B (en) | Static melting crystallizer for material purification and separation | |
| CN203155229U (en) | Continuous nitration system with automatic overflow function | |
| CN203196371U (en) | Continuous potassium dihydrogen phosphate crystallization device | |
| CN202052347U (en) | Continuous material dissolving and column chromatography recrystallization purification system | |
| CN202715268U (en) | Crystallizer | |
| CN102350082B (en) | Crystallizing tank used for Arteether | |
| CN204219828U (en) | Energy-saving crystallizer | |
| CN206240108U (en) | A kind of crystallizer | |
| CN104801060A (en) | Industrial crystallization kettle | |
| CN204699436U (en) | A kind of industrial crystallization kettle | |
| CN203954727U (en) | A kind of glucose equipment of crystallisation by cooling | |
| CN218321282U (en) | Melting crystallization system for purifying crude nervonic acid by using rapeseed oil as source | |
| CN102350292A (en) | Reaction kettle for preparing dihydroartemisinin | |
| CN203634852U (en) | Crystallization kettle for producing perfluoroethylene propylene | |
| CN209475628U (en) | Crystallization apparatus is used in a kind of preparation of organic synthesis raw material | |
| CN206853677U (en) | Recrystallize reactor | |
| CN102895934A (en) | Improved cold and heat exchange reaction kettle | |
| CN207575943U (en) | A kind of purification used filter crystallization apparatus of chemical industry | |
| CN206027141U (en) | Be used for refine crystallization device of chlorophenol | |
| CN204767570U (en) | Concentrated crystallization kettle of material | |
| CN205495587U (en) | Reaction kettle |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20120425 |