CN106955501A - A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device - Google Patents
A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device Download PDFInfo
- Publication number
- CN106955501A CN106955501A CN201710387472.0A CN201710387472A CN106955501A CN 106955501 A CN106955501 A CN 106955501A CN 201710387472 A CN201710387472 A CN 201710387472A CN 106955501 A CN106955501 A CN 106955501A
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- CN
- China
- Prior art keywords
- crystallizing tank
- tank
- medicament
- chilled brine
- steam
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0063—Control or regulation
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- Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Devices For Medical Bathing And Washing (AREA)
- Catching Or Destruction (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device, is characterized in being made up of crystallizing tank, manhole, medicament temperatuer detector, temp probe, anchor agitator, stirring motor, steam pipeline, chilled brine delivery pipe, steam output pipe, chilled brine efferent duct, drain hole.Crystallizing tank is interlayer crystallizing tank, and its tank base is provided with medicament temperatuer detector and temp probe；Middle part is provided with above anchor agitator, crystallization tank and is provided with stirring motor in crystallizing tank, and power is provided for anchor agitator；Steam pipeline, steam output pipe are separately installed with above and below crystallizing tank side, it is cold above and below opposite side to be separately installed with jelly salt solution delivery pipe, chilled brine efferent duct for the input and output of steam, for the input and output of chilled brine；Drain hole is located at crystallization pot bottom, is exported for bulk drug.
Description
Technical field
The present invention relates to a kind of temperature detection device, especially a kind of bulk drug crystallizing tank pharmaceutical preparations temperature sensing dress
Put.
Background technology
The production of nasmil bulk drug, is that first Cromoglycic acid diethylester, sodium acid carbonate are put into added with alcohol solvent
In crystallizing tank, then by the various raw materials progress sufficiently stirring in crystallizing tank, heating, general heating will reach 75 degree, from
And form nasmil bulk drug.Then activated carbon is added in nasmil bulk drug and decolourized.Stand four hours
Afterwards, chilled brine is added into crystallizing tank to be cooled.When temperature is reduced to less than 5 degree, stop chilled brine cooling.Now tie
Nasmil bulk drug in brilliant tank just forms crystalline solid, you can is exported from drain hole in being sent to centrifuge and carries out subsequent technique
Processing.In this production process, medicament in crystallizing tank is heated, the real time temperature of cooling is observed, grasps extremely important.At present,
Because the medicament temperature sensing meter and temp probe of crystallizing tank are arranged at the top of the tank body of crystallizing tank, and because being provided with crystallizing tank
Agitator, medicament temperature sensing meter temp probe is unable to the whole tank body of up/down perforation, when the medicament in crystallizing tank is less than material temperature
When spending surveymeter temp probe, then the gas phase temperature of medicament in tank can only be detected, it is impossible to detect liquidus temperature, so as to cause
The actual temperature of medicament in crystallizing tank can not be grasped in real time, carry out normally heating, cool control, influences the production of bulk drug.
The solution that this problem has never had.
The content of the invention
For current, because the medicament temperature sensing meter and temp probe of crystallizing tank are arranged at the top of the tank body of crystallizing tank,
And because being provided with agitator in crystallizing tank, medicament temperature sensing meter temp probe is unable to the whole tank body of up/down perforation, works as crystallizing tank
In medicament be less than medicament temperature sensing meter temp probe when, then can only detect the gas phase temperature of medicament in tank, it is impossible to detect
To liquidus temperature, so as to cause that the actual temperature of medicament in crystallizing tank can not be grasped in real time, normally heat, cool and control
The problem of system, influence production of raw medicine, the purpose of the present invention is to disclose a kind of bulk drug crystallizing tank pharmaceutical preparations temperature sensing dress
Put.
The technical scheme that a kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device of the present invention is used is：It will pacify at present
Medicament temperature sensing meter and temp probe at the top of crystallization tank are installed to the tank base of crystallizing tank.
A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device of the present invention, is characterized in by crystallizing tank, manhole, medicament
Temperatuer detector, temp probe, anchor agitator, stirring motor, steam pipeline, chilled brine delivery pipe, steam output pipe,
Chilled brine efferent duct, drain hole composition.Crystallizing tank be interlayer crystallizing tank, its tank base be provided with medicament temperatuer detector and
Temp probe；Middle part is provided with above anchor agitator, crystallization tank and is provided with stirring motor in crystallizing tank, is anchor formula stirring
Device provides power；Steam pipeline, steam output pipe are separately installed with above and below crystallizing tank side, for the input of steam
With output, it is cold above and below opposite side to be separately installed with jelly salt solution delivery pipe, chilled brine efferent duct, for chilled brine
Input and output.Drain hole is located at crystallization pot bottom, is exported for bulk drug.
Because medicament temperatuer detector and temp probe are arranged on the bottom of crystallizing tank, no matter medicament in crystallizing tank is more
It is few, the real time temperature of medicament in tank can be detected, is easy to grasp and control to medicament temperature in crystallizing tank.
A kind of beneficial effect of bulk drug crystallizing tank pharmaceutical preparations temperature detection device of the present invention is：Device installs easy,
Temperature detection in real time, accurately, is easy to the grasp to medicament temperature in crystallizing tank, carries out normally heating, cool control.
Brief description of the drawings
Fig. 1 is a kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device structural representation.
In figure, 1, crystallizing tank；2nd, manhole；3rd, medicament temperatuer detector；4th, temp probe；5th, anchor agitator；6th, stir
Motor；7th, steam pipeline；8th, chilled brine delivery pipe 9, steam output pipe；10th, chilled brine efferent duct；11st, drain hole.
Fig. 2 is the structural representation of the crystallizing tank medicament temperature detection counter device before improving.
In figure, 1, crystallizing tank；2nd, manhole；3rd, medicament temperatuer detector；4th, temp probe；5th, anchor agitator；6th, stir
Motor；7th, steam pipeline；8th, chilled brine delivery pipe 9, steam output pipe；10th, chilled brine efferent duct；11st, drain hole.
Embodiment
A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device, is characterized in by crystallizing tank 1, manhole 2, medicament temperature
Detection meter 3, temp probe 4, anchor agitator 5, stirring motor 6, steam pipeline 7, chilled brine delivery pipe 8, steam output
Pipe 9, chilled brine efferent duct 10, drain hole 11 are constituted.Crystallizing tank 1 is interlayer crystallizing tank, and its tank base is provided with medicament temperature
Degree detection meter 2 and temp probe 4；Middle part is provided with above anchor agitator 5, the tank body of crystallizing tank 1 and is provided with stirring in crystallizing tank 1
Motor 6, stirring motor 6 is that anchor agitator 5 provides power；It is defeated that steam is separately installed with above and below the side of crystallizing tank 1
Pipe 7, steam output pipe 9 are sent, it is cold above and below opposite side to be separately installed with jelly salt solution conveying for the input and output of steam
Pipe 8, chilled brine efferent duct 10, for the input and output of chilled brine.Drain hole 11 is located at the bottom of crystallizing tank 1, for bulk drug
Output.
Because medicament temperatuer detector 3 and temp probe 4 are arranged on the bottom of crystallizing tank 1, no matter the medicament in crystallizing tank 1
How much, the real time temperature of medicament in tank can be detected, is easy to grasp and control to medicament temperature in crystallizing tank 1.
Claims (1)
1. a kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device, it is characterized in that by crystallizing tank, manhole, medicament temperature detection
Meter, temp probe, anchor agitator, stirring motor, steam pipeline, chilled brine delivery pipe, steam output pipe, chilled brine
Efferent duct, drain hole composition；Crystallizing tank is interlayer crystallizing tank, and its tank base is provided with medicament temperatuer detector and temperature is visited
Head；Middle part is provided with above anchor agitator, crystallization tank and is provided with stirring motor in crystallizing tank, is provided for anchor agitator
Power；Steam pipeline, steam output pipe are separately installed with above and below crystallizing tank side, for steam input with it is defeated
Go out, it is cold above and below opposite side to be separately installed with jelly salt solution delivery pipe, chilled brine efferent duct, for the input of chilled brine
With output；Drain hole is located at crystallization pot bottom, is exported for bulk drug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710387472.0A CN106955501A (en) | 2017-05-27 | 2017-05-27 | A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710387472.0A CN106955501A (en) | 2017-05-27 | 2017-05-27 | A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106955501A true CN106955501A (en) | 2017-07-18 |
Family
ID=59482610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710387472.0A Pending CN106955501A (en) | 2017-05-27 | 2017-05-27 | A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106955501A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201051852Y (en) * | 2007-04-28 | 2008-04-30 | 江苏中棉紫光棉业科技有限公司 | Device for hydrolyzing propagation protein and thalli protein |
| CN102423543A (en) * | 2011-09-02 | 2012-04-25 | 江苏斯威森生物医药工程研究中心有限公司 | Vinpocetine special-purpose crystallization pot |
| CN202223931U (en) * | 2011-10-17 | 2012-05-23 | 瓮福（集团）有限责任公司 | Electronic grade chemical crystallizer |
| CN203620538U (en) * | 2013-11-25 | 2014-06-04 | 漯河市永利食品有限公司 | Milk emulsification tank with temperature sensor |
| CN104338343A (en) * | 2013-08-07 | 2015-02-11 | 湖北宜恒茶油产业科技有限责任公司 | Temperature-adjustable crystallizing tank |
| CN204217808U (en) * | 2014-09-22 | 2015-03-25 | 扬州日顿食品实业发展有限公司 | A kind of beverage processing tank with function of temperature control |
| CN204337816U (en) * | 2014-11-17 | 2015-05-20 | 广东立国制药有限公司 | A kind of medicine production crystallizing tank |
| CN204841014U (en) * | 2015-06-17 | 2015-12-09 | 江阴市江中设备制造有限公司 | Sulphide crystallization equipment |
| CN206853175U (en) * | 2017-05-27 | 2018-01-09 | 湖北华丹医药科技股份有限公司 | A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device |
-
2017
- 2017-05-27 CN CN201710387472.0A patent/CN106955501A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201051852Y (en) * | 2007-04-28 | 2008-04-30 | 江苏中棉紫光棉业科技有限公司 | Device for hydrolyzing propagation protein and thalli protein |
| CN102423543A (en) * | 2011-09-02 | 2012-04-25 | 江苏斯威森生物医药工程研究中心有限公司 | Vinpocetine special-purpose crystallization pot |
| CN202223931U (en) * | 2011-10-17 | 2012-05-23 | 瓮福（集团）有限责任公司 | Electronic grade chemical crystallizer |
| CN104338343A (en) * | 2013-08-07 | 2015-02-11 | 湖北宜恒茶油产业科技有限责任公司 | Temperature-adjustable crystallizing tank |
| CN203620538U (en) * | 2013-11-25 | 2014-06-04 | 漯河市永利食品有限公司 | Milk emulsification tank with temperature sensor |
| CN204217808U (en) * | 2014-09-22 | 2015-03-25 | 扬州日顿食品实业发展有限公司 | A kind of beverage processing tank with function of temperature control |
| CN204337816U (en) * | 2014-11-17 | 2015-05-20 | 广东立国制药有限公司 | A kind of medicine production crystallizing tank |
| CN204841014U (en) * | 2015-06-17 | 2015-12-09 | 江阴市江中设备制造有限公司 | Sulphide crystallization equipment |
| CN206853175U (en) * | 2017-05-27 | 2018-01-09 | 湖北华丹医药科技股份有限公司 | A kind of bulk drug crystallizing tank pharmaceutical preparations temperature detection device |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170718 |