CN102423456B - Traditional Chinese medicine preparation for treating chronic atrophic gastritis - Google Patents
Traditional Chinese medicine preparation for treating chronic atrophic gastritis Download PDFInfo
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- CN102423456B CN102423456B CN 201110370474 CN201110370474A CN102423456B CN 102423456 B CN102423456 B CN 102423456B CN 201110370474 CN201110370474 CN 201110370474 CN 201110370474 A CN201110370474 A CN 201110370474A CN 102423456 B CN102423456 B CN 102423456B
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating chronic atrophic gastritis. Traditional Chinese medicine doctors think that the key point of the chronic atrophic gastritis pathogenesis is in excess within deficiency, the spleen stomach deficiency is taken as root, the blood stasis stagnation is taken as symptom. The disease treatment is performed by aiming at the purposes of reinforcing spleen and stomach, supplementing qi and activating blood circulation. Therefore, Chinese herbal medicines like Chinese angelica, radix rehmanniae, Chinese wolfberry, radix ophiopogonis, fried atractylodes, aucklandia root, licorice, red sage root, leech, peach seed, rhizoma ligustici wallichii, paniculate swallowwort root, radix paeoniae alba, corydalis tuber and radix curcumae are carefully chosen for preparing decoction. The clinical application shows that the effective rate reaches 93.3%, the treatment cost is low, no side-effect is generated, the traditional Chinesemedicine preparation of the invention deserves the clinical expansion and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of chronic atrophic gastritis.
Background technology
Chronic atrophic gastritis is common disease of stomach.The hobby of arteriosclerosis, stomach blood flow deficiency, cigarette,wine and tea etc. all damages the barrier function of gastric mucosa easily and causes chronic atrophic gastritis.During chronic atrophic gastritis, gastric mucosa atrophy and to be replaced by the epithelial cell of intestinal be that intestinalization is given birth to; Inflammation continue to develop, and then the cell growth is not true to type, and becomes between namely.Primary disease belongs to " feeling of fullness " in Chinese medicine, categories such as " stomachaches ", and it is foster how to be become homeless by stomach, and the deficiency of vital energy can not promote blood operation, makes congestion gather the stomach network, so the basic pathogenesis of primary disease is spleen deficiency and blood stasis.The chronic atrophic gastritis clinical manifestation only indigestion symptom such as moves back for glutted, the belch of upper abdomen, stomach poor appetite, is destroyed because of gastric anti-pernicious anemia factor sometimes, and vitamin B12 malabsorption can cause anemia.
Chronic atrophic gastritis is fallen ill many clinically, easily repeatedly, is difficult to cure, companion's moderate or the above dysplasia of moderate and the big intestinal epithelial metaplasia person of imperfection are easy to canceration, Western medicine still lacks determined curative effect to primary disease at present, the medicine that side effect is little, and the treatment by Chinese herbs primary disease has its unique advantage.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of chronic atrophic gastritis.The traditional Chinese medical science thinks that the key of chronic atrophic gastritis pathogenesis is deficiency complicated with excess, and losing void with taste is basis, and blood stasis stagnates and is mark.The primary disease treatment should be with invigorating the spleen and regulating the stomach, and benefiting QI for activating blood circulation is method.
The objective of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment chronic atrophic gastritis is made by following parts by weight of Chinese traditional medicine: Radix Angelicae Sinensis 15-20 part, Radix Rehmanniae 10-15 part, Fructus Lycii 20-25 part, Radix Ophiopogonis 8-12 part, Rhizoma Atractylodis Macrocephalae (parched) 10-15 part, Radix Aucklandiae 8-13 part, Radix Glycyrrhizae 15-20 part, Radix Salviae Miltiorrhizae 5-9 part, Hirudo 7-9 part, Semen Persicae 9-13 part, Rhizoma Chuanxiong 10-15 part, Radix Cynanchi Paniculati 7-9 part, Radix Paeoniae Alba 9-13 part, Rhizoma Corydalis 7-10 part, Radix Curcumae 5-9 part.
Preferably, the Chinese medicine preparation of this treatment chronic atrophic gastritis is made by following parts by weight of Chinese traditional medicine: 17 parts of Radix Angelicae Sinensis, 13 parts in the Radix Rehmanniae, 23 parts of Fructus Lycii, 10 parts of Radix Ophiopogonis, 12 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10 parts of the Radix Aucklandiae, 17 parts in Radix Glycyrrhizae, 7 parts of Radix Salviae Miltiorrhizaes, 8 parts of Hirudos, 11 parts in Semen Persicae, 13 parts of Rhizoma Chuanxiongs, 8 parts of Radix Cynanchi Paniculatis, 11 parts of Radix Paeoniae Alba, 9 parts of Rhizoma Corydalis, 7 parts of Radix Curcumaes.
With above crude drug decocting method routinely, fry in shallow oil into decoction and take.
The void of taste is controlled in Radix Angelicae Sinensis, the Radix Rehmanniae, Fructus Lycii, Radix Ophiopogonis, Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and replenishing QI in the side to set upright gas; The Radix Aucklandiae, Radix Glycyrrhizae relieving spasm to stop pain; Radix Salviae Miltiorrhizae, Hirudo, Semen Persicae dissipating blood stasis tissue regeneration promoting; Rhizoma Chuanxiong, Radix Cynanchi Paniculati, Radix Paeoniae Alba, Rhizoma Corydalis, Radix Curcumae regulating QI to relieve pain.
Clinical data
1, physical data
120 routine patients all from year January in February, 2006 to 2008 my gate examine and inpatient, be divided into two groups at random.60 examples are organized in treatment, male 41 examples, women 19 examples; Minimum 27 years old of age, maximum 64 years old, average 43.5 years old; The course of disease is the longest 12.5, and is the shortest 1.5 years.Matched group 60 examples, male 39 examples, women 21 examples; Minimum 26 years old of age, maximum 63 years old, average 43 years old; The course of disease is the longest 13 years, and is the shortest 1 year.Two groups of patient's sexes, ages, there are no significant for course of disease difference (P＞0.05), has comparability.
2, diagnostic criteria
The diagnostic criteria of the national chronic gastritis seminar public affairs knowledge suggestion that this group 120 example all can be formulated with reference to Chinese Medical Association's digestology in 2000 and criteria for classification and make a definite diagnosis.
3, Therapeutic Method
The treatment group adopts the Chinese medicine preparation for the treatment of chronic atrophic gastritis of the present invention, get Radix Angelicae Sinensis 17g, Radix Rehmanniae 13g, Fructus Lycii 23g, Radix Ophiopogonis 10g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Radix Aucklandiae 10g, Radix Glycyrrhizae 17g, Radix Salviae Miltiorrhizae 7g, Hirudo 8g, Semen Persicae 11g, Rhizoma Chuanxiong 13g, Radix Cynanchi Paniculati 8g, Radix Paeoniae Alba 11g, Rhizoma Corydalis 9g, Radix Curcumae 7g, day potion, every dose adds water 500ml, fries in shallow oil back extracting juice 300ml and divides 3 taking medicine before meal to use.Matched group is taken the each 1g of vitacoenzyme (Hubei Ezhou City Biochemical Pharmaceutical Factory), every day 3 times.Two groups was a course for the treatment of with 4 months all, carried out efficacy evaluation after 1 course for the treatment of of taking medicine.
4, criterion of therapeutical effect
Draft with reference to " chronic gastritis combination of Chinese and Western medicine diagnosis, dialectical and criterion of therapeutical effect (tentative program) " [2].Be as the criterion with interior check result to treat preceding and to stop to treat the back two weeks.Produce effects: clinical symptoms, sign disappear or basic the disappearance; Greyish white or the pale district of fibergastroscope check gastric mucosa disappears or basic the disappearance, and exposed vessel is unclear; Mottled rotten to the corn the disappearance or basic disappearance of mucosa, the coarse injustice of mucosa, graininess disappear substantially, and bile reflux obviously improves.Effectively: clinical cardinal symptom, sign obviously alleviate; Greyish white or the pale district of fibergastroscope check gastric mucosa scope is dwindled more than 1/2, and vasoganglion dwindles more than 1/2, and mucosa is coarse, graininess alleviates, and mottled erosion disappears substantially, and bile reflux improves.Invalid: clinical symptoms, sign, fibergastroscopy all do not have obvious change or counter see increase the weight of.
5, therapeutic outcome
Take medicine and add up therapeutic effect after a course for the treatment of.60 examples are organized in treatment, produce effects 31 examples (51.7%) wherein, and effective 25 examples (41.7%), invalid 4 examples (6.7%), total effective rate is 93.3%; Matched group 60 examples, produce effects 21 examples (35.0%) wherein, effective 26 examples (43.3%), invalid 13 examples (21.7%), total effective rate is 78.3%; Two groups of curative effects relatively exist significant difference that (P＜001) is arranged.
The specific embodiment
Embodiment one: get Radix Angelicae Sinensis 17g, Radix Rehmanniae 13g, Fructus Lycii 23g, Radix Ophiopogonis 10g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Radix Aucklandiae 10g, Radix Glycyrrhizae 17g, Radix Salviae Miltiorrhizae 7g, Hirudo 8g, Semen Persicae 11g, Rhizoma Chuanxiong 13g, Radix Cynanchi Paniculati 8g, Radix Paeoniae Alba 11g, Rhizoma Corydalis 9g, Radix Curcumae 7g, day potion, every dose adds water 500ml, fries in shallow oil back extracting juice 300ml and divides 3 taking medicine before meal to use.
Embodiment two: get Radix Angelicae Sinensis 15g, Radix Rehmanniae 10g, Fructus Lycii 20g, Radix Ophiopogonis 12g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Radix Aucklandiae 8g, Radix Glycyrrhizae 15g, Radix Salviae Miltiorrhizae 9g, Hirudo 7g, Semen Persicae 9g, Rhizoma Chuanxiong 15g, Radix Cynanchi Paniculati 9g, Radix Paeoniae Alba 13g, Rhizoma Corydalis 7g, Radix Curcumae 9g, day potion, every dose adds water 500ml, fries in shallow oil back extracting juice 300ml and divides 3 taking medicine before meal to use.
Embodiment three: get Radix Angelicae Sinensis 20g, Radix Rehmanniae 15g, Fructus Lycii 25g, Radix Ophiopogonis 8g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Aucklandiae 13g, Radix Glycyrrhizae 20g, Radix Salviae Miltiorrhizae 5g, Hirudo 9g, Semen Persicae 13g, Rhizoma Chuanxiong 10g, Radix Cynanchi Paniculati 7g, Radix Paeoniae Alba 9g, Rhizoma Corydalis 10g, Radix Curcumae 5g, day potion, every dose adds water 500ml, fries in shallow oil back extracting juice 300ml and divides 3 taking medicine before meal to use.
Claims (1)
1. Chinese medicine preparation for the treatment of chronic atrophic gastritis is characterized in that this Chinese medicine preparation made by following parts by weight of Chinese traditional medicine: Radix Angelicae Sinensis 17g, Radix Rehmanniae 13g, Fructus Lycii 23g, Radix Ophiopogonis 10g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Radix Aucklandiae 10g, Radix Glycyrrhizae 17g, Radix Salviae Miltiorrhizae 7g, Hirudo 8g, Semen Persicae 11g, Rhizoma Chuanxiong 13g, Radix Cynanchi Paniculati 8g, Radix Paeoniae Alba 11g, Rhizoma Corydalis 9g, Radix Curcumae 7g.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201110370474 CN102423456B (en) | 2011-11-03 | 2011-11-03 | Traditional Chinese medicine preparation for treating chronic atrophic gastritis |
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| CN 201110370474 CN102423456B (en) | 2011-11-03 | 2011-11-03 | Traditional Chinese medicine preparation for treating chronic atrophic gastritis |
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| CN102423456B true CN102423456B (en) | 2013-09-11 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670971B (en) * | 2012-06-28 | 2014-03-26 | 高文学 | Chinese medicinal composition for treating chronic atrophic gastritis |
| CN105213780B (en) * | 2015-11-09 | 2018-09-28 | 中国人民解放军第二军医大学 | A kind of Chinese medicine composition that treating chronic gastritis and its application |
| CN114028486A (en) * | 2021-06-02 | 2022-02-11 | 陈凤羽 | Propolis stomach invigorating pill |
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2011
- 2011-11-03 CN CN 201110370474 patent/CN102423456B/en active Active
Non-Patent Citations (4)
| Title |
|---|
| 中医治疗慢性萎缩性胃炎近况;唐存雄;《广西中医药》;19971231;第20卷(第6期);第43页左栏 * |
| 中医药治疗慢性萎缩性胃炎概况;梁光宇 等;《湖北中医杂志》;20071231;第29卷(第11期);第64页右栏至第65页左栏 * |
| 唐存雄.中医治疗慢性萎缩性胃炎近况.《广西中医药》.1997,第20卷(第6期),第43页左栏. |
| 梁光宇 等.中医药治疗慢性萎缩性胃炎概况.《湖北中医杂志》.2007,第29卷(第11期),第64页右栏至第65页左栏. |
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