CN102423371A - Chinese medicinal drug withdrawal cigarette and preparation process thereof - Google Patents
Chinese medicinal drug withdrawal cigarette and preparation process thereof Download PDFInfo
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- CN102423371A CN102423371A CN2011103862213A CN201110386221A CN102423371A CN 102423371 A CN102423371 A CN 102423371A CN 2011103862213 A CN2011103862213 A CN 2011103862213A CN 201110386221 A CN201110386221 A CN 201110386221A CN 102423371 A CN102423371 A CN 102423371A
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Abstract
The invention discloses a Chinese medicinal drug withdrawal cigarette and a preparation process thereof and relates to a Chinese medicine and a preparation process thereof. Thick paste which is blended into the cigarette comprises the following components in percentage by weight: 20.12 percent of deer fetus and red ginseng paste, 23.50 percent of prepared rehmannia root, 9.63 percent of Chinese wolfberry, 16.23 percent of suberect spatholobus stem, 20.32 percent of liquoric root and 10.20 percent of mint. The preparation process comprises the following steps of: leaching, filtering and concentrating to obtain the thick paste, adding ethanol to ensure that the alcohol-containing concentration reaches 45 percent, standing for 8 hours, filtering, recovering the ethanol under reduced pressure until the product is odorless, placing the obtained thick paste of which the relative density is 1.29 to 1.31 at the temperature of 71 DEG C for later use, and blending the prepared thick paste into a cigarette to obtain a finished cigarette. The smoke is inhaled through a respiratory tract and then enters the deep part of the respiratory tract, a fluid and pulmonary alveolus, so that the permeability of intestinal capillary walls and alveolar walls is strengthened; and the smoke contains Chinese medicinal active ingredients and enters the capillaries so as to achieve the effects of detoxification and drug withdrawal, partial smoke is absorbed by skin and a gastrointestinal tract, and about 70 to 90 percent of smoke is discharged from urine through metabolism, so that the symptoms of a drug addict are relieved.
Description
Technical field
The present invention relates to a kind of Chinese medicine and preparation technology thereof, particularly a kind of Chinese medicine drug rehabilitation cigarette and preparation technology thereof.
Background technology
Experiment showed, that entanglement has treatment and return action to neurotransmitter in the Chinese medicine drug rehabilitation.The curative effect of Chinese medicine drug rehabilitation is singly on the control withdrawal symptom, and to quite grow the treatment and the rehabilitation of protracted abstinence symptom (psa)s such as the insomnia of surviving in the years, anxiety, pain after the detoxification, and in the abolishment that the physiology of drugs is craved for of surviving for a long time.Chinese medicine drug rehabilitation has fast, the anti-characteristic such as revert to take drugs of heart-addiction prevented, anxiety, disconnected addiction, and the superstitious prescription of unusual peculiar Chinese medicine is got through the human body main threads, and compromise animal nerve style is strengthened blood flow.
All carry out drug addiction treatment to have dependent Western medicine both at home and abroad, this type Western medicine often is difficult for effecting a permanent cure, and the relapse rate of the poison of reverting to take drugs is high, and cost is high, has certain toxic and side effects.Drug addiction treatment for opiate addiction is the problem of all tackling key problems in research in countries in the world always; Western medicine methadone (methadone) that adopts at present and clonidine hydrochloride sheet are after taking, with untoward reaction such as xerostomia, asthenia, dizzy, constipation and body property hypotension.Become the new developing direction of research topic and utilize natural plants such as Chinese herbal medicine to quit drug abuse.Narcotics (drugs) is meant that continuous use back is prone to produce dependency; The medicine of ability addiction; Comprising: opiates, cocaines, cannabis, a synthetic anesthesia type medicine class, very serious to human health damage, once use a large amount of or frequent application can cause poisonings, deadly.The situation of drug-breaking medicine is at present: all carry out drug addiction treatment to have dependent Western medicine both at home and abroad, this type Western medicine often is difficult for effecting a permanent cure, and the relapse rate of the poison of reverting to take drugs is high, and cost is high, has certain toxic and side effects.To how giving up drug addiction is the problem of all tackling key problems in research in countries in the world always; Be difficult to find curative effect drug-relief medicine accurately at present; Utilizing natural plants such as Chinese herbal medicine to quit drug abuse becomes the new developing direction of this research topic, but does not see prescription listing evident in efficacy yet, and many places are in experimental stage.The key of Chinese medicine drug rehabilitation is reasonable proportioning component and pharmaceutical technology thereof, awaits in this respect constantly exploring.
For this reason, the applicant had once applied in 1998.11.25 that " drug rehabilitation cigarette and preparation technology thereof " patent No. was: 98121001.5, received effect preferably; But abnormal flavour is arranged on the mouthfeel, and drug effect is limited, and prescription is not too reasonable; Withdrawal symptoms such as the pain that relieves the pain are not obvious, and backwardness is also arranged on the method for preparing.
In disclosed Chinese medicine drug rehabilitation prescription; Prescription is basically to abolish the drugs physical dependence; Decline is to the drugs physiological dependence, " treating the poisonous disease with poisonous drugs " general plan be main, ignored with Chinese medicine and remedied the human body nutrient; Strengthen health to working as power, the booster immunization function is closed the endocrine function with treatment human body inner phase, is made it the coupling of the balanced aspect of metabolism.
And on preparation technology, adopt traditional prepared.Comprise decocting cooking method, infusion process, percolation, improvement gelatin method, circumfluence method etc., there is more shortcoming in traditional method: the decocting method loss of effective components is more, especially water insoluble active ingredient; In the leaching process organic solvent might with the effective ingredient effect, make it lose original effectiveness; Non-active ingredients can not be removed to greatest extent, and enrichment factor is not high enough; Except that effective ingredient, often impurity is more in the extracting solution, and a small amount of liposoluble constituent is still arranged, give refining bring unfavorable; The high-temperature operation meeting causes a large amount of decomposition of thermal sensitivity effective ingredient.
It is thus clear that; Existing prescription is basically to abolish the drugs physical dependence; Decline is to the drugs physiological dependence, " treating the poisonous disease with poisonous drugs " general plan be main, ignored with Chinese medicine and remedied the human body nutrient; Strengthen health to working as power, the booster immunization function is closed the endocrine function, is made it to reach balanced metabolic coupling with treatment human body inner phase.
With satisfy have more scientific, not only abolished drugs physical dependence but also booster immunization function and cure the human body inner phase and close the endocrine function, make it to reach balanced metabolic rational Match; Adopt scientific modern Chinese medicine extraction technology simultaneously; Both improved labor productivity; Increase the extraction of middle pharmaceutically active ingredient again, become problem demanding prompt solution in the Chinese medicine drug rehabilitation.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine drug rehabilitation cigarette and preparation technology thereof, proposed a kind of prescription of rational Match, is raw material with the natural Chinese medicinal herb; Process the pain relieving medicine after the coupling; Call in then in the Nicotiana tabacum L., as carrier, adopt the form of Medicated cigarette with cigarette; Reach drug rehabilitation, improve health QI and blood balance, aim of alleviating pain through smoking, and tool this a kind of new preparation technology is proposed.
The present invention is realized by following technical scheme:
A kind of Chinese medicine drug rehabilitation cigarette, it is processed by following method:
1) press column weight amount percentage ratio and take by weighing raw material, promptly call in the thick paste percentage ratio component in the cigarette:
Deer ginseng cream 20.12%, Radix Rehmanniae Preparata 23.50%, Fructus Lycii 9.63%, Caulis Spatholobi 16.23%, Radix Glycyrrhizae 20.32%, Herba Menthae 10.20%;
2) lixiviate: get under 40 ℃ of the deer ginseng cream, Radix Rehmanniae Preparata, Fructus Lycii, Caulis Spatholobi, Radix Glycyrrhizae, Herba Menthae and extract 34min with extractor, extraction ratio is 92.5%, leaves standstill 4 hours;
3) filter: filter filters removes residue;
4) concentrate: filtrating is condensed into thick paste, adds ethanol again and makes and contain determining alcohol and reach 45%, leaves standstill 8 hours, filters, and decompression backwater ethanol to the relative density of tasteless gained thick paste in the time of 71 ℃ is that 1.29-1.31 is subsequent use;
5) call in the cigarette: the above-mentioned thick paste that makes is called in make finished cigarettes in the cigarette and get final product.
Described a kind of Chinese medicine drug rehabilitation cigarette, wherein the consumption of raw material is:
Deer ginseng cream 1610 grams, Radix Rehmanniae Preparata 1880 grams, Fructus Lycii 770 grams, Caulis Spatholobi 1298 grams, Radix Glycyrrhizae 1626 grams, Herba Menthae 816 grams.
A kind of preparation technology of Chinese medicine drug rehabilitation cigarette:
1) press column weight amount percentage ratio and take by weighing raw material, promptly call in the thick paste percentage ratio component in the cigarette:
Deer ginseng cream 20.12%, Radix Rehmanniae Preparata 23.50%, Fructus Lycii 9.63%, Caulis Spatholobi 16.23%, Radix Glycyrrhizae 20.32%, Herba Menthae 10.20%;
2) lixiviate: get under 40 ℃ of the deer ginseng cream, Radix Rehmanniae Preparata, Fructus Lycii, Caulis Spatholobi, Radix Glycyrrhizae, Herba Menthae and extract 34min with extractor, extraction ratio is 92.5%, leaves standstill 4 hours;
3) filter: filter filters removes residue;
4) concentrate: filtrating is condensed into thick paste, adds ethanol again and makes and contain determining alcohol and reach 45%, leaves standstill 8 hours, filters, and decompression backwater ethanol to the relative density of tasteless gained thick paste in the time of 71 ℃ is that 1.29-1.31 is subsequent use;
5) call in the cigarette: the above-mentioned thick paste that makes is called in make finished cigarettes in the cigarette and get final product.
The preparation technology of described a kind of Chinese medicine drug rehabilitation cigarette, wherein the consumption of raw material is:
Deer ginseng cream 1610 grams, Radix Rehmanniae Preparata 1880 grams, Fructus Lycii 770 grams, Caulis Spatholobi 1298 grams, Radix Glycyrrhizae 1626 grams, Herba Menthae 816 grams.
Advantage of the present invention and good effect are:
1. the set of dispense of Chinese herbal medicine of the present invention ratio is through repeatedly clinical verification; Can make full use of the pharmacological action of each component, maximum performance drug effect makes QI-blood circulation unobstructed; Make body nature toxin expelling; And the adjusting central nervous system disorder, correcting intractable insomnia, prescription the present invention of the whole immunologic function of enhancing body is a new effective way with cigarette as the carrier of pain relieving medicine.The patient sucks the back the cigarette smog that contains effective components of Chinese medicinal; Suck through respiratory tract; Cigarette smog is that gas vapor and the grit mixture that the Nicotiana tabacum L. imperfect combustion is produced decomposes synthetic in the lit end temperature up to 900 degrees centigrade of generation conditions; Contain in the smog that chemical compound combines in effective components of Chinese medicinal and the smog, make the inspirator reach analgesic effect.Smog sucks through respiratory tract, gets into the respiratory tract deep, the advanced dynamic process of fluid and alveolar, lung tissue gap and lymphatics of lung exchange operation; Intestinal capillary wall and alveolar wall permeability strengthen; Contain effective components of Chinese medicinal entering blood capillary in the smog and reach detoxifcation, the effect of drug rehabilitation, most of poisonous substances are by RE; Through urine, poisonous substance is discharged.Breathe smog and get into human body, part is also arranged through skin stomach function regulating intestinal absorption, about 70～90% discharge from urine through metabolism, make the junkie sx, rehabilitation rapidly.The set of dispense ratio of Chinese herbal medicine of the present invention is a pharmacological action that makes full use of each component through repeatedly clinical verification, maximum performance drug effect, effectively also rapid analgesic prescription.
2. preparation technology of the present invention uses the modern Chinese medicine extractive technique to the proprietary characteristics of Chinese medicine against drug dependence, has both met the Chinese medical theory of Chinese medicine against drug dependence, can reach the yield of raising effective ingredient and the purpose of purity again.Extract with extractor and to have realized the lixiviate of low micro content natural activity composition, filtration, concentrate, pouring process, directly obtain purified product, cost be merely conventional extract about 1/4th.
The specific embodiment
Below in conjunction with embodiment the present invention is made further detailed description:
Get raw material: deer ginseng cream 1610 grams are the rectangular blocks of brownish black; Feeble QI, it is little sweet to distinguish the flavor of; Radix Rehmanniae Preparata 1880 grams are cut sheet and are used; The dry rattan of Caulis Spatholobi 1298 grams is removed branch and leaf, and section is dried; Herba Menthae 816 gram cured leaf or Herba Menthae herbs; Fructus Lycii 770 grams are used as medicine with the plant drying mature fruit; Radix Glycyrrhizae 1626 grams remove removing LU, stem foot, and branch fork fibrous root, the section that is cut into suitable length is shone to half-dried, breaks into wisp, shines to absolutely dry again, puts aeration-drying place, and is mothproof; Extract: get under 40 ℃ of the deer ginseng cream, Radix Rehmanniae Preparata, Fructus Lycii, Caulis Spatholobi, Radix Glycyrrhizae, Herba Menthae and extract 34min with extractor, extraction ratio is 92.5%, leaves standstill 4 hours; Filter: filter filters removes residue; The extracting solution of medical material separates the processing with ceramic membrane through high speed centrifugation, adopts 0.08 micron alumina sintering film to carry out fine straining, and diameter is greater than 0.08 micron insoluble granule in the removal solution.Adopt NF membrane that the extracting solution of handling well is carried out cold concentration again; Concentrate: filtrating is condensed into thick paste, adds ethanol again and makes and contain determining alcohol and reach 45%, leaves standstill 8 hours; Filter, decompression backwater ethanol to the relative density of tasteless gained thick paste in the time of 71 ℃ is that 1.29-1.31 is subsequent use; The above-mentioned thick paste that makes called in make finished cigarettes in the cigarette and get final product.
The pharmacology of Chinese medicinal ingredients of the present invention is:
1. deer is joined cream: nourishing blood and invigorating qi, regulating menstruation is cold.Be used to suffer from a deficiency of the kidney deficiency of both QI and blood, irregular menstruation, abdominal pain in menstruation.
2. Radix Rehmanniae Preparata: meridian distribution of property and flavor: sweet, tepor.Return liver, kidney channel.Function cures mainly: nourishing YIN and supplementing blood, beneficial essence is filled out marrow.Be used for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.
3. Caulis Spatholobi: nature and flavor are bitter, sweet, and temperature is returned liver, kidney channel, enriches blood, and invigorates blood circulation collateral dredging.Be used for blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
4. Herba Menthae: stimulate and suppress neural effect: the Herba Menthae product has the effect that stimulates nervus centralis, and acting on skin has the sense of burning and creeping chill simultaneously, and it has the effect that suppresses and benumb again to sensory nerve ending; Therefore, can be used as counter-stimulus and cutaneous stimulant.Both skin pruritus was had antiallergic and itching-relieving action, again neuralgia and rheumatic arthritis were had tangible alleviation and analgesic activity.
5. Fructus Lycii: the treating the liver kidney yin is lost, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
6. Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Medicinal liquid of the present invention extracts and adopts the circulating ultrasonic extractor, and ultrasonic extractor is high-power multistage energy gathering type ultrasonic power, and the large power supersonic field directly acts on the extraction material, and the ultrasonic energy utilization rate is high, and extraction effect is good; Extracting mode is ultrasonic dynamic outer circulating extracting; Power of motor 400 W; Supersonic frequency is from motion tracking 20KHz frequency, ultrasonic power 4800 W, maximum heating power 5000 W; Outer circulation mixing speed (rpm): 0-1500, be integrated digital display stepless speed regulation, controllable temperature ℃: room temperature-60 disposal ability (kg/hr): 70.0--150.0; Extract the workshop and can adopt automatization, link to each other with the automatization chamber, control the process instrument of each technique unit, input-output equipment such as valve through the configuration fieldbus.Can be through the shared realization execute-in-place of hardware, simply, conveniently, reliably.Extract the workshop by extract, evaporation, concentrate, operations such as separation and drying form, extraction element, thin film evaporation unit, triple effect enrichment facility, disc centrifuge and spray-drying installation are existing complexes.
Claims (4)
1. Chinese medicine drug rehabilitation cigarette is characterized in that it is processed by following method:
1) press column weight amount percentage ratio and take by weighing raw material, promptly call in the thick paste percentage ratio component in the cigarette:
Deer ginseng cream 20.12%, Radix Rehmanniae Preparata 23.50%, Fructus Lycii 9.63%, Caulis Spatholobi 16.23%, Radix Glycyrrhizae 20.32%, Herba Menthae 10.20%;
2) lixiviate: get under 40 ℃ of the deer ginseng cream, Radix Rehmanniae Preparata, Fructus Lycii, Caulis Spatholobi, Radix Glycyrrhizae, Herba Menthae and extract 34min with extractor, extraction ratio is 92.5%, leaves standstill 4 hours;
3) filter: filter filters removes residue;
4) concentrate: filtrating is condensed into thick paste, adds ethanol again and makes and contain determining alcohol and reach 45%, leaves standstill 8 hours, filters, and decompression backwater ethanol to the relative density of tasteless gained thick paste in the time of 71 ℃ is that 1.29-1.31 is subsequent use;
5) call in the cigarette: the above-mentioned thick paste that makes is called in make finished cigarettes in the cigarette and get final product.
2. a kind of Chinese medicine drug rehabilitation cigarette according to claim 1, wherein the consumption of raw material is:
Deer ginseng cream 1610 grams, Radix Rehmanniae Preparata 1880 grams, Fructus Lycii 770 grams, Caulis Spatholobi 1298 grams, Radix Glycyrrhizae 1626 grams, Herba Menthae 816 grams.
3. the preparation technology of Chinese medicine drug rehabilitation cigarette is characterized in that:
1) press column weight amount percentage ratio and take by weighing raw material, promptly call in the thick paste percentage ratio component in the cigarette:
Deer ginseng cream 20.12%, Radix Rehmanniae Preparata 23.50%, Fructus Lycii 9.63%, Caulis Spatholobi 16.23%, Radix Glycyrrhizae 20.32%, Herba Menthae 10.20%;
2) lixiviate: get under 40 ℃ of the deer ginseng cream, Radix Rehmanniae Preparata, Fructus Lycii, Caulis Spatholobi, Radix Glycyrrhizae, Herba Menthae and extract 34min with extractor, extraction ratio is 92.5%, leaves standstill 4 hours;
3) filter: filter filters removes residue;
4) concentrate: filtrating is condensed into thick paste, adds ethanol again and makes and contain determining alcohol and reach 45%, leaves standstill 8 hours, filters, and decompression backwater ethanol to the relative density of tasteless gained thick paste in the time of 71 ℃ is that 1.29-1.31 is subsequent use;
5) call in the cigarette: the above-mentioned thick paste that makes is called in make finished cigarettes in the cigarette and get final product.
4. the preparation technology of a kind of Chinese medicine drug rehabilitation cigarette according to claim 3, wherein the consumption of raw material is:
Deer ginseng cream 1610 grams, Radix Rehmanniae Preparata 1880 grams, Fructus Lycii 770 grams, Caulis Spatholobi 1298 grams, Radix Glycyrrhizae 1626 grams, Herba Menthae 816 grams.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103862213A CN102423371A (en) | 2011-11-29 | 2011-11-29 | Chinese medicinal drug withdrawal cigarette and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103862213A CN102423371A (en) | 2011-11-29 | 2011-11-29 | Chinese medicinal drug withdrawal cigarette and preparation process thereof |
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| Publication Number | Publication Date |
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| CN102423371A true CN102423371A (en) | 2012-04-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2011103862213A Pending CN102423371A (en) | 2011-11-29 | 2011-11-29 | Chinese medicinal drug withdrawal cigarette and preparation process thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103815543A (en) * | 2014-03-26 | 2014-05-28 | 福建中烟工业有限责任公司 | Chinese style health-care cigarette and manufacturing method thereof |
| CN108208925A (en) * | 2016-12-09 | 2018-06-29 | 金朝晖 | Anti-additive medicament containing anti-additive medicament sucks device, cigarette filter and cigarette |
-
2011
- 2011-11-29 CN CN2011103862213A patent/CN102423371A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103815543A (en) * | 2014-03-26 | 2014-05-28 | 福建中烟工业有限责任公司 | Chinese style health-care cigarette and manufacturing method thereof |
| CN108208925A (en) * | 2016-12-09 | 2018-06-29 | 金朝晖 | Anti-additive medicament containing anti-additive medicament sucks device, cigarette filter and cigarette |
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Application publication date: 20120425 |