CN102406831A - Traditional Chinese medicine composition for insomnia and dreaminess and preparation method thereof - Google Patents
Traditional Chinese medicine composition for insomnia and dreaminess and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for insomnia and dreaminess, which comprises the following raw materials in parts by weight: 30 parts of radix rehmanniae recen, 20 parts of flos albiziae, 18 parts of radix codonopsis pilosulae, 15 parts of radix ophiopogonis, 12 parts of radix achyranthis bidentatae, 15 parts of radix scrophulariae, 10 parts of radix salviae miltiorrhizae, 10 parts of caulis polygoni multiflori, 9 parts of radix astragali, 9 parts of glossy privet fruit, 8 parts of spina date seed, 8 parts of pinellia ternate, 9 parts of Chinese yam, 7 parts of radix puerariae, 8 parts of liquorice and 5 parts of poria. Clinical verification shows that the traditional Chinese medicine composition for treating insomnia and dreaminess has the effect of curing insomnia, and is non-toxic and harmless to human bodies. Treats both principal and secondary aspects of diseases, has no side effect, low price, simple and convenient preparation and wide application prospect.
Description
Technical field
The invention belongs to the Chinese medicine technical field of pharmaceuticals, concrete, relate to pharmaceutical composition of a kind of Cure for insomnia dreaminess and preparation method thereof.
Background technology
Insomnia is modal sleep disorder, and main clinical manifestation is a difficulty falling asleep, and the back of sleeping is prone to wake up, and has difficulty in going to sleep after waking up, and early awakening is with dreaminess; Dizziness, headache, lethargy is depressed, the extremity fatigue and weak; The memory persistence goes down, bradykinesia etc., and the patient feels that antisecosis is not good next day, even anxiety, nervous or sense of depression are arranged; Severe patient has heart rate to accelerate, fervescence, and autonomic nerve symptoms such as peripheral vessels contraction still have after the awakening that asthenia is unhappy, sense of discomfort such as have one's head in the clouds.Its many by internal injury caused by excess of seven emotions, ponder over too, due to being terrified suddenly, innate deficiency or the body deficiency due to old age etc., qi-blood disharmony, imbalance of YIN and YANG, visceral dysfunction so that the mind is tired, mental derangement must not be slept.An investigation of the U.S. 1992 is also found; 1/3 the adult dormancy of ating fault in is in the previous year arranged; World Health Organization (WHO) shows in basic medical unit prescription on individual diagnosis patient's survey result 25916 examples in 15 bases of 14 countries; 27% people has sleeping problems, and the patient who is diagnosed as the insomnia half the near the actual diseased number.
Doctor trained in Western medicine is started with from following three aspects on the insomnia disease rule: 1, with the ascending reticular activating system of sedative hypnotic drug with the blocking-up reticular formation of brain stem, thereby reach the effect of tranquilizing soporific, represent medicine to have: stabilize, estazolam etc.2, central stimulants: because of the insomniac can not fall asleep night, brain can not get having a rest, and daytime is sleepy, impels daytime excited with central stimulants, represents medicine to have: caffeine etc.3, regulate the neural medicine of nutrient plant; Have suitable ratio to cause because of the autonomic nervous dysfunction in the insomnia case, the initial stage can be selected for use and regulated the neural medicine of nutrient plant, and only a few patient can obtain certain effect.Represent medicine to have: oryzanol tablets, vitamin B1, vitamin B6 sheet.In case suffer from the insomnia, some people can adopt western medicine, but in therapeutic process, tends to find own sleepy weak, unstable on foot; Hypomnesis, forgetful, thirsty etc., also excitement, impatience, inappetence can appear in the somebody, go out erythra, and hemogram abnormity can appear in a few peoples, the patient of long-term prescription is very easily caused the dependence of medicine.In case the drug withdrawal meeting produces bad dream, the appearance that this can bring mental disorder, depression for a lot of patients, often side effect is big, and is habit-forming easily, produces dependency.
The traditional Chinese medical science about be insomnia, i.e. the cause of disease of insomnia thinks for a long time: being insomnia is because a variety of causes has influence on and defends gas and go into the moon by sun, make negative and positive intercept so.Chinese medicine is being brought into play huge effect aspect the insomnia medical treatment good effect being arranged.Because of its treating both the principal and secondary aspects of a disease, safe without toxic side effect and cause compatriots' extensive use and concern.Insomnia preferably will be nursed one's health with Chinese medicine comprehensively.But general Chinese medicine is because condition is limit and is difficult to reach theoretic therapeutic effect, and some belongs to cures the symptoms, not the disease, and some interrupts using owing to uncertain therapeutic efficacy is fixed in application process, in addition, also has the technical problem of specific aim difference.
Summary of the invention
The purpose of this invention is to provide a kind of treating both the principal and secondary aspects of a disease, have no side effect, safe ready, cheap pure traditional Chinese compound medicine.
The application inventor combines secret prescription handed down in the family from generation to generation according to forefathers' experience and oneself practice of practising medicine for many years, through the research to Chinese medicine, and combines dialectical demonstration; In many ways collect the length of many families, seek therapeutic regimen, from motherland's medical treasure-house; Filter out the natural Chinese medicine of enriching yin and nourishing kidney, tranquilizing by nourishing the heart,, skim the cream off milk by the theory of Chinese medical science prescription; Its performance is cleared away heart-fire, and the place is tired, YIN nourishing and the production of body fluid promoting, the effect of calming the nerves and nourishing heart, and adopts the natural Chinese medicines raw material, through systematic study, science compatibility; Be mixed with the Chinese medicine composition that is used for insomnia and dreamful sleep of the present invention meticulously in conjunction with traditional lunar physics technique, insomnia and dreamful sleep had the effect of rapid healing.
For realizing above-mentioned purpose, the technical scheme that the present invention adopts is following:
A kind of Chinese medicine composition of Cure for insomnia dreaminess, it is got by following weight proportioning feedstock production,
Radix Rehmanniae 20-35 part, Flos Albiziae 18-30 part, Radix Codonopsis 15-30 part, Radix Ophiopogonis 12-25 part,
Radix Achyranthis Bidentatae 10-18 part, Radix Scrophulariae 10-18 part, Radix Salviae Miltiorrhizae 8-10 part, Caulis Polygoni Multiflori 8-10 part,
Radix Astragali 8-10 part, Fructus Ligustri Lucidi 5-10 part, Semen Ziziphi Spinosae 5-10 part, Rhizoma Pinelliae 5-8 part,
Rhizoma Dioscoreae 8-10 part, Radix Puerariae 5-10 part, Radix Glycyrrhizae 8-10 part, Poria 5-8 part.
A kind of Chinese medicine composition of Cure for insomnia dreaminess, it is preferably got by following weight proportioning feedstock production,
30 parts of Radix Rehmanniae, 20 parts of Flos Albiziaes, 18 parts of Radix Codonopsis, 15 parts of Radix Ophiopogonis,
12 parts of Radix Achyranthis Bidentataes, 15 parts of Radix Scrophulariaes, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Caulis Polygoni Multiflori,
9 parts of the Radixs Astragali, 9 parts of Fructus Ligustri Lucidi, 8 parts of Semen Ziziphi Spinosaes, 8 parts of the Rhizoma Pinelliaes,
9 parts of Rhizoma Dioscoreaes, 7 parts of Radix Puerariaes, 8 parts in Radix Glycyrrhizae, 5 parts in Poria.
Dosage form and usage: our pharmaceutically dosage form is a decoction.Be decocted in water for oral dose, potion on the one, 15 days is a course of treatment.
Decoct twice, take by weighing each component medical material (proportioning unit: gram), with 500ml cold water said medicine was soaked 2 hours earlier, changed slow fire boiling after intense fire boils 30 minutes, get the 150ml medicine juice according to the above ratio; Add hot water 400ml second time, changed slow fire boiling after intense fire boils 4050 minutes, get the 150ml medicine juice, twice medicine juice mixed, respectively obeyed 150ml, warm water delivery service sooner or later in 2 hours after meal.Period in a medicine avoids pungent food and cold and cool food, avoids feelings will to stimulate, and life is regular.
The excellent results of Chinese medicine composition of Cure for insomnia dreaminess of the present invention and preparation method thereof is:
1. medicament of the present invention is processed by pure Chinese medicine, and each component meets the pharmaceutical control law regulation, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and does not contain chemical components, does not contain hormone, has no side effect, and treating both the exterior and interior reaches better enriching yin and nourishing kidney, tranquilizing by nourishing the heart effect;
2. this medicament short treating period, total effective rate is high, and more the back is difficult for recurrence.
3. technology of the present invention is simple, has reduced production cost, has alleviated patient's financial burden.
The specific embodiment
Below will describe the present invention in detail through correlation step.It will be understood by those skilled in the art that following method that illustrates for example and step only are used to explain the present invention but not are used for it is made any restriction.
Embodiment 1
A kind of Chinese medicine composition of Cure for insomnia dreaminess, it is got by following weight proportioning feedstock production,
30 parts of Radix Rehmanniae, 20 parts of Flos Albiziaes, 18 parts of Radix Codonopsis, 15 parts of Radix Ophiopogonis,
12 parts of Radix Achyranthis Bidentataes, 15 parts of Radix Scrophulariaes, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Caulis Polygoni Multiflori,
9 parts of the Radixs Astragali, 9 parts of Fructus Ligustri Lucidi, 8 parts of Semen Ziziphi Spinosaes, 8 parts of the Rhizoma Pinelliaes,
9 parts of Rhizoma Dioscoreaes, 7 parts of Radix Puerariaes, 8 parts in Radix Glycyrrhizae, 5 parts in Poria.
Embodiment 2
Take by weighing each component medical material (proportioning unit: gram), with 500ml cold water said medicine was soaked 2 hours earlier, changed slow fire boiling after intense fire boils 30 minutes, get the 150ml medicine juice in embodiment 1 said ratio; Add hot water 400ml second time, changed slow fire boiling after intense fire boils 40 minutes, get the 150ml medicine juice, twice medicine juice mixed, respectively obeyed 150ml, warm water delivery service sooner or later in 2 hours after meal.
Potion on the one, two weeks were a course of treatment, and period in a medicine avoids pungent food and cold and cool food, avoids feelings will to stimulate, and life is regular.
Embodiment 3
Clinical data
Following standard is formulated in the selected reference of case " insomnia definition, diagnosis and Drug therapy expert common recognition (draft) " and " Chinese mental disorder classification and diagnostic criteria (CCMD-3) ": the incubation period of 1. sleeping is long: time for falling asleep surpasses 30min; 2. obstacle is kept in sleep: the number of times of awakening night is greater than 2 times; 3. sleep quality descends: shallow, the dreaminess of sleeping; 4. total sleep time shortens: be less than 5 hours; 5. residual effect is big in the daytime: sensation giddy in inferior morning, lassitude, drowsiness, weak etc.
Exclusion standard:
1. the age is under-18s, over-65s person; 2. serious body illness and principal characteristic mental sickness person; 3. and with other drug and antipsychotic drug person; 4. serious suicidal attempt and actor are arranged; 5. gestation and women breast-feeding their children; 6. mismatch therapist.
Select clinic case 105 example to be the treatment group at random, male 58 examples, women 47 examples, age 18-60 year, 40 years old mean age, the course of disease 6 months-11 years; Select the same period 78 examples as matched group, male 36 examples, women 42 examples, age 25-64 year, the course of disease 1 year-10 years.Two groups at aspects such as sex, age, the course of disease, the state of an illness through statistical procedures, there was no significant difference (P＞0.05) has comparability.
Therapeutic Method:
105 examples are organized in treatment, take medicine of the present invention, potion on the one, and two weeks were a course of treatment; Matched group 78 examples are taken estazolam, and 2mg is each, once-a-day, take warm boiled water before the sleep every night on time.Two groups all continuously clothes around, do not obey other drug during the treatment.
Efficacy assessment standard:
" traditional Chinese medical science disease diagnosis criterion of therapeutical effect " formulated with reference to State Administration of Traditional Chinese Medicine combines clinical drafting.Insomnia primary symptom before and after two groups of patient treatments is scored.Score standard: severe: the difficulty of falling asleep, wake up more, dreaminess, wake up early morning, and be lasting appearance, and residual effect is obvious in the daytime, remembers 3 fens; Moderate: above disease is interrupted appearance, and residual effect is slight in the daytime, remembers 2 fens; Slightly: disease is light, or occurs once in a while, remembers 1 fen; No associated conditions note 0 minute.Cure: the insomnia primary symptom disappears; Produce effects: insomnia primary symptom integration reduces＞2/3; Effectively: insomnia primary symptom integration reduces 1/3-2/3; Invalid: insomnia primary symptom integration reduces＜1/3.
Therapeutic outcome:
105 examples are organized in treatment, cure 98 examples (93.33%), produce effects 3 examples (2.86%), effective 2 examples (1.90%), invalid 2 examples (1.90%), total effective rate 98%; Matched group 78 examples are cured 25 examples (31.25%), produce effects 29 examples (36.25%), effective 10 examples (12.5%), invalid 14 examples (17.5%), total effective rate 82.5%.Two groups of curative effects are relatively checked through X2, and the treatment group obviously is superior to matched group, has significant difference (P＜0.01).
Embodiment 4
Exemplary embodiments
Case 1: Chen, man, 28 years old; The irregular serious insomnia that causes of secular operating pressure and daily schedule shows as 2:00 AM and has difficulty in going to sleep basically before, can not sleep soundly after falling asleep; Again and again have a dream, the length of one's sleep of every day, generally about 4 hours, energy did not recover after sleeping; Once used a variety of Drug therapys, fruit does not take effect.Use medicine of the present invention after course of treatment, sleep quality obviously improves, and has a dream no longer again and again; Energy is good more a lot of than in the past after waking up, and continues to use medicine of the present invention, after two courses of treatment; Extend to 7 hours the length of one's sleep, uses again after two courses of treatment, extends to 8 hours the length of one's sleep; Sleep quality obviously improves, and energy is also vigorous, and work efficiency has had large increase.Followed up a case by regular visits to six months, and do not have recurrence.
Case 2: consolidate certain, the woman, 51 years old, needed just can fall asleep night in 2-3 hour, wakes up 2-3 time conscious dizziness on daytime, weak after falling asleep at least.Look into: red tongue, yellow and greasy fur, thready pulse and counting.Dialectical is heart-liver blood deficiency, type of phlegm-heat attacking the heart.Give decoction of the present invention and take a course of treatment, symptom subtracts greatly, continues and takes a course of treatment, and it is normal to fall asleep, and daytime is full of physical strength.Follow up a case by regular visits to half a year, not recurrence again.
Case 3: Wu, the woman, 58 years old, suffered from the insomnia companioned with headache nearly 10 years, the back of sleeping is prone to wake up, and is difficult to sleeping after waking up again; Very then lie awake all night, headache as split, the time heavy when light, being irritable and irascible, anorexia, thirst and liking drink; Red eyes and bitter taste in the mouth, yellowish or reddish urine, constipation, red tongue, yellow and thin fur, wiry and frequent pulse.Repeatedly capable electroencephalogram, cranium brain CT examination do not see obviously that unusually the state of an illness day by day increases the weight of.Through taking medicine of the present invention after two courses of treatment, the symptom that is prone to wake up is obviously improved, even if early awakening can also reenter and sleep 1-2 hour, take a course of treatment again after, sleep is basic to recover normal, transference cures such as headache.Followed up a case by regular visits to 1 year, and do not have recurrence.
Above-mentioned each Chinese medicine that the present invention adopts is made compatibility mutually, can bring into play its collaborative effect of curing the disease, and has drug effect between each composition of used raw material of Chinese medicine and is interweaved and mutually promotes and coordinate usefulness; Through clinical verification, insomnia and dreamful sleep there is good therapeutic effect, in the medical practice in nearly ten years of the applicant; The case number of curing is numerous; All obtain good effect, and with low cost, alleviate patient's burden.
The application be used for insomnia and dreamful sleep Chinese medicine composition with low cost, evident in efficacy, have broad application prospects.
Claims (3)
1. Chinese medicine composition that is used for insomnia and dreamful sleep; It is got by following weight proportioning feedstock production, Radix Rehmanniae 20-35 part, Flos Albiziae 18-30 part, Radix Codonopsis 15-30 part, Radix Ophiopogonis 12-25 part, Radix Achyranthis Bidentatae 10-18 part, Radix Scrophulariae 10-18 part, Radix Salviae Miltiorrhizae 8-10 part, Caulis Polygoni Multiflori 8-10 part, Radix Astragali 8-10 part, Fructus Ligustri Lucidi 5-10 part, Semen Ziziphi Spinosae 5-10 part, Rhizoma Pinelliae 5-8 part, Rhizoma Dioscoreae 8-10 part, Radix Puerariae 5-10 part, Radix Glycyrrhizae 8-10 part, Poria 5-8 part.
2. the described Chinese medicine composition of claim 1; It gets 30 parts of Radix Rehmanniae, 20 parts of Flos Albiziaes, 18 parts of Radix Codonopsis, 15 parts of Radix Ophiopogonis, 12 parts of Radix Achyranthis Bidentataes, 15 parts of Radix Scrophulariaes, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Caulis Polygoni Multiflori, 9 parts of the Radixs Astragali, 9 parts of Fructus Ligustri Lucidi, 8 parts of Semen Ziziphi Spinosaes, 8 parts of the Rhizoma Pinelliaes, 9 parts of Rhizoma Dioscoreaes, 7 parts of Radix Puerariaes, 8 parts in Radix Glycyrrhizae, 5 parts in Poria by following weight proportioning feedstock production.
3. claim 1 or the 2 described Chinese medicine compositions purposes in preparation Cure for insomnia dreaminess medicine.
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| CN103815543A (en) * | 2014-03-26 | 2014-05-28 | 福建中烟工业有限责任公司 | Chinese style health-care cigarette and manufacturing method thereof |
| CN103977247A (en) * | 2014-05-31 | 2014-08-13 | 全椒县尹氏油脂有限公司 | Chinese medicine for treating excessive night dream |
| CN104983902A (en) * | 2015-06-23 | 2015-10-21 | 中国人民解放军第三军医大学 | Traditional Chinese medicine composition for treating insomnia and dreaminess and preparation method and application thereof |
| CN105362609A (en) * | 2015-12-07 | 2016-03-02 | 王建 | Traditional Chinese medicine preparation for treating insomnia and dreaminess |
| CN105596721A (en) * | 2015-09-18 | 2016-05-25 | 于洁 | Traditional Chinese medicine for treatment of insomnia |
| CN108244637A (en) * | 2018-03-20 | 2018-07-06 | 罗正都 | It is a kind of using bamboo magma as the biosynthesis healthy liquid of primary raw material |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103815543A (en) * | 2014-03-26 | 2014-05-28 | 福建中烟工业有限责任公司 | Chinese style health-care cigarette and manufacturing method thereof |
| CN103977247A (en) * | 2014-05-31 | 2014-08-13 | 全椒县尹氏油脂有限公司 | Chinese medicine for treating excessive night dream |
| CN104983902A (en) * | 2015-06-23 | 2015-10-21 | 中国人民解放军第三军医大学 | Traditional Chinese medicine composition for treating insomnia and dreaminess and preparation method and application thereof |
| CN105596721A (en) * | 2015-09-18 | 2016-05-25 | 于洁 | Traditional Chinese medicine for treatment of insomnia |
| CN105362609A (en) * | 2015-12-07 | 2016-03-02 | 王建 | Traditional Chinese medicine preparation for treating insomnia and dreaminess |
| CN108244637A (en) * | 2018-03-20 | 2018-07-06 | 罗正都 | It is a kind of using bamboo magma as the biosynthesis healthy liquid of primary raw material |
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| CN102406831B (en) | 2013-06-19 |
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