CN102380048B - Traditional Chinese medicine composition for treating hypertension - Google Patents
Traditional Chinese medicine composition for treating hypertension Download PDFInfo
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- CN102380048B CN102380048B CN 201110333178 CN201110333178A CN102380048B CN 102380048 B CN102380048 B CN 102380048B CN 201110333178 CN201110333178 CN 201110333178 CN 201110333178 A CN201110333178 A CN 201110333178A CN 102380048 B CN102380048 B CN 102380048B
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- 206010020772 Hypertension Diseases 0.000 title claims abstract description 22
- 239000003814 drug Substances 0.000 title claims abstract description 21
- 239000000203 mixture Substances 0.000 title claims abstract description 11
- 241000237903 Hirudo Species 0.000 claims description 9
- 241000628997 Flos Species 0.000 claims description 8
- 241000756943 Codonopsis Species 0.000 claims description 7
- 230000001631 hypertensive effect Effects 0.000 claims description 7
- 241000219780 Pueraria Species 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 3
- 241000132012 Atractylodes Species 0.000 abstract 1
- 244000035851 Chrysanthemum leucanthemum Species 0.000 abstract 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 abstract 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 abstract 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 abstract 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 abstract 1
- 235000009685 Crataegus X maligna Nutrition 0.000 abstract 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 abstract 1
- 235000009486 Crataegus bullatus Nutrition 0.000 abstract 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 abstract 1
- 235000009682 Crataegus limnophila Nutrition 0.000 abstract 1
- 235000004423 Crataegus monogyna Nutrition 0.000 abstract 1
- 240000000171 Crataegus monogyna Species 0.000 abstract 1
- 235000002313 Crataegus paludosa Nutrition 0.000 abstract 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 abstract 1
- 241000305492 Gastrodia Species 0.000 abstract 1
- 241000545744 Hirudinea Species 0.000 abstract 1
- 240000007890 Leonurus cardiaca Species 0.000 abstract 1
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 240000001341 Reynoutria japonica Species 0.000 abstract 1
- 235000018167 Reynoutria japonica Nutrition 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 description 7
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 4
- 229910052753 mercury Inorganic materials 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000008030 elimination Effects 0.000 description 3
- 238000003379 elimination reaction Methods 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 239000002893 slag Substances 0.000 description 3
- 208000007530 Essential hypertension Diseases 0.000 description 2
- 208000031226 Hyperlipidaemia Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 241000305491 Gastrodia elata Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 201000004239 Secondary hypertension Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000001773 anti-convulsant effect Effects 0.000 description 1
- 230000003276 anti-hypertensive effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000003727 cerebral blood flow Effects 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 239000003218 coronary vasodilator agent Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
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- 230000002028 premature Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine composition for treating hypertension, which is characterized in that the traditional Chinese medicine composition is prepared by the following components in parts by weight: 6-10 parts of leech, 2-4 parts of tall gastrodia tuber, 1-2 parts of radix rehmanniae preparata, 10-13 parts of hawthorn, 9-10 parts of wild chrysanthemum, 3-5 parts of narrowleaf rockvine root or herb, 6-8 parts of tuber fleeceflower root, 1-2 parts of motherwort fruit, 7-10 parts of Chinese magnoliavine fruit, 2-4 parts of common macrocarpium fruit, 5-10 parts of kudzuvine root, 2-5 parts of pilose Asiabell root and 7-10 parts of largehead atractylodes rhizome. The traditional Chinese medicine composition has obvious efficacy for treating the hypertension and complications caused by the hypertension.
Description
Technical field the present invention relates to a kind of pharmaceutical composition, relates to more specifically a kind of hypertensive Chinese medicine composition for the treatment of.
Background technology
Hypertension (Hypertension) is a kind of global common disease, and the prevalence of countries in the world is up to 10%-20%, and can cause the pathological changes of cerebrovascular, heart, kidney, and agnogenic hyperpietic claims essential hypertension or secondary hypertension.In China, the main directly complication of hypertension is cerebrovascular, especially cerebral hemorrhage.The primary hypertension patient that one group of 312 example is in hospital was followed up a case by regular visits to for a long time through 15 years-18 years, because the heart, brain, dead 97 examples of kidney complication account for 74.6% of whole causes of the death.In 596 routine senile hypertensions follow-up observation in perspective 27 months research, the heart, cerebrovascular accumulate incidence are 68.79%, and the cerebrovascular accumulate incidence is 36.91%.Studies show that blood pressure is higher, the incidence rate of complication is also higher.
At present, if the drug main Western medicine of Hypertension disease.Because doctor trained in Western medicine can only be controlled, can not thoroughly cure hypertension, hyperlipidemia, hyperglycemia, therefore must take medicine all the life, the burden but also the long-term taking that have not only greatly increased the weight of the patient also can have side effects.
Summary of the invention
The present invention provides a kind of hypertensive Chinese medicine composition for the treatment of for overcoming above-mentioned the deficiencies in the prior art, selects Chinese herbal medicine, and it is obvious to have an antihypertensive effect, the characteristics that side effect is little.
The present invention adopts following technical scheme to realize:
A kind ofly treating hypertensive Chinese medicine composition, it is characterized in that, is to be made by the component of following parts by weight: Hirudo 6-10 part, Rhizoma Gastrodiae 2-4 part, Radix Rehmanniae Preparata 1-2 part, Fructus Crataegi 10-13 part, Flos Chrysanthemi Indici 9-10 part, Radix seu Herba Tetrastigmatis Hypoglauci 3-5 part, Radix Polygoni Multiflori 6-8 part, Fructus Leonuri 1-2 part, Fructus Schisandrae Chinensis 7-10 part, Fructus Corni 2-4 part, Radix Puerariae 5-10 part, Radix Codonopsis 2-5 part, Rhizoma Atractylodis Macrocephalae 7-10 part.
Further, a kind ofly treat hypertensive Chinese medicine composition, it is characterized in that: the parts by weight of each component are as follows: 8 parts of Hirudos, 3 parts in Rhizoma Gastrodiae, 2 parts of Radix Rehmanniae Preparata, 11 parts of Fructus Crataegis, 9 parts of Flos Chrysanthemi Indicis, 4 parts of Radix seu Herba Tetrastigmatis Hypoglaucis, 7 parts of Radix Polygoni Multiflori, 1 part of Fructus Leonuri, 8 parts of Fructus Schisandrae Chinensis, 3 parts of Fructus Corni, 6 parts of Radix Puerariaes, 4 parts of Radix Codonopsis, 8 parts of the Rhizoma Atractylodis Macrocephalaes.
Wherein in each component of the present invention:
Hirudo, the popular name Hirudo is the traditional extraordinary medicinal aquatic animal of China, the traditional Chinese medical science was used as medicine after its dry products was concocted, and had the effects such as treatment apoplexy, hypertension, the clear stasis of blood, traumatic injury.
Rhizoma Gastrodiae, Rhizoma Gastrodiae have calmness, analgesia, anticonvulsant action; Can increase cerebral blood flow, reduce cerebral vascular resistance, slightly shrink cerebrovascular, increase the coronary vasodilator flow; Can reduce blood pressure, decreased heart rate has protective effect to myocardial ischemia; Gastrodia elata polysaccharide has immunocompetence.
Flos Chrysanthemi Indici is slightly cold, and is hot, bitter; Return lung, Liver Channel.Heat-clearing and toxic substances removing; The dispelling wind suppressing the hyperactive liver.
Fructus Leonuri, acrid in the mouth, hardship, cold nature.GUIXIN bag, Liver Channel.
Preparation and instructions of taking: the impurity place to go with each crude drug is decocted in water for oral dose potion on the one.Ten days is a course for the treatment of.
The clinical observation performance:
Feng, man, 60 years old, retired worker.Patient suffers from hypertension two more than ten years, often feels dizzy headache.Fluctuation of blood pressure is between 190/90-200/100mmHg.Take medicine over the past half year, dizzy headache sx↓, blood pressure is gradually normal.
Lee so-and-so, the man, 56 years old, the patient suffered from hypertension, hyperlipidemia 7 years, high pressure 190/ low pressure 120mmHg, and premature coronary heart disease is often had a headache, dizzy, insomnia reaches 2 years.Blood pressure is always fluctuated, controls undesirablely, adheres to taking this medicine 1 year, and it is normal that the blood pressure blood fat recovers substantially.
Teacher Liu, the woman, 53 years old, live alone as a widow, live on one's own life, active.Height 156cm, body weight 60kg has been diagnosed as hypertension, blood fat raises, often walking and early morning motion exercise.Take this medicine one wheat harvesting period, recovery is desirable.
Yellow master worker, the man, 51 years old, suffered from hypertension 5 years, low pressure 100 mercury column, high pressure 160 mercury column were taken medicine of the present invention three months, low pressure 80 mercury column, high pressure 130 mercury column are followed up a case by regular visits to 1 year blood pressure and are kept more stable.
The specific embodiment
Embodiment 1:
With Hirudo 6g, Rhizoma Gastrodiae 2g, Radix Rehmanniae Preparata 1g, Fructus Crataegi 10g, Flos Chrysanthemi Indici 9g, Radix seu Herba Tetrastigmatis Hypoglauci 3g, Radix Polygoni Multiflori 6g, Fructus Leonuri 1g, Fructus Schisandrae Chinensis 7g, Fructus Corni 2g, Radix Puerariae 5g, Radix Codonopsis 2g, Rhizoma Atractylodis Macrocephalae 7g adds water 1000ml and decocts, and the elimination slag becomes the 500ml decoction, takes every day once, and ten days is a course for the treatment of.
Embodiment 2:
With Hirudo 10g, Rhizoma Gastrodiae 4g, Radix Rehmanniae Preparata 2g, Fructus Crataegi 13g, Flos Chrysanthemi Indici 10g, Radix seu Herba Tetrastigmatis Hypoglauci 5g, Radix Polygoni Multiflori 8g, Fructus Leonuri 2g, Fructus Schisandrae Chinensis 10g, Fructus Corni 4g, Radix Puerariae 10g, Radix Codonopsis 5g, Rhizoma Atractylodis Macrocephalae 10g adds water 1000ml and decocts, and the elimination slag becomes the 500ml decoction, takes every day once, and ten days is a course for the treatment of.
Embodiment 3:
With Hirudo 8g, Rhizoma Gastrodiae 3g, Radix Rehmanniae Preparata 2g, Fructus Crataegi 11g, Flos Chrysanthemi Indici 9g, Radix seu Herba Tetrastigmatis Hypoglauci 4g, Radix Polygoni Multiflori 7g, Fructus Leonuri 1g, Fructus Schisandrae Chinensis 8g, Fructus Corni 3g, Radix Puerariae 6g, Radix Codonopsis 4g, Rhizoma Atractylodis Macrocephalae 8g adds water 1000ml and decocts, and the elimination slag becomes the 500ml decoction, takes every day once, and ten days is a course for the treatment of.
Claims (2)
1. the hypertensive Chinese medicine composition for the treatment of is characterized in that, is to be made by the component of following parts by weight: Hirudo 6-10 part, Rhizoma Gastrodiae 2-4 part, Radix Rehmanniae Preparata 1-2 part, Fructus Crataegi 10-13 part, Flos Chrysanthemi Indici 9-10 part, Radix seu Herba Tetrastigmatis Hypoglauci 3-5 part, Radix Polygoni Multiflori 6-8 part, Fructus Leonuri 1-2 part, Fructus Schisandrae Chinensis 7-10 part, Fructus Corni 2-4 part, Radix Puerariae 5-10 part, Radix Codonopsis 2-5 part, Rhizoma Atractylodis Macrocephalae 7-10 part.
2. the hypertensive Chinese medicine composition for the treatment of as claimed in claim 1, it is characterized in that: the parts by weight of each component are as follows: 8 parts of Hirudos, 3 parts in Rhizoma Gastrodiae, 2 parts of Radix Rehmanniae Preparata, 11 parts of Fructus Crataegis, 9 parts of Flos Chrysanthemi Indicis, 4 parts of Radix seu Herba Tetrastigmatis Hypoglaucis, 7 parts of Radix Polygoni Multiflori, 1 part of Fructus Leonuri, 8 parts of Fructus Schisandrae Chinensis, 3 parts of Fructus Corni, 6 parts of Radix Puerariaes, 4 parts of Radix Codonopsis, 8 parts of the Rhizoma Atractylodis Macrocephalaes.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110333178 CN102380048B (en) | 2011-10-28 | 2011-10-28 | Traditional Chinese medicine composition for treating hypertension |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110333178 CN102380048B (en) | 2011-10-28 | 2011-10-28 | Traditional Chinese medicine composition for treating hypertension |
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| Publication Number | Publication Date |
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| CN102380048A CN102380048A (en) | 2012-03-21 |
| CN102380048B true CN102380048B (en) | 2013-03-13 |
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| CN 201110333178 Active CN102380048B (en) | 2011-10-28 | 2011-10-28 | Traditional Chinese medicine composition for treating hypertension |
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| CN105381154A (en) * | 2015-12-16 | 2016-03-09 | 顾海峰 | Pharmaceutical composition containing moringa oleifera and preparation method of preparation of pharmaceutical composition |
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Address after: 364300 Longyan City, Fujian Province Qingyun Wuping County Hill Industrial Park 8 Building No. 2 Patentee after: Hu Keding Address before: 315318 Wu Meicun, Henghe Town, Cixi, Zhejiang Patentee before: Hu Keding |
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Owner name: NANTONG HONGCI PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: HU KEDING Effective date: 20140616 |
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Free format text: CORRECT: ADDRESS; FROM: 364300 LONGYAN, FUJIAN PROVINCE TO: 226200 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20140616 Address after: 226200 chemical industry park, Nantong, Qidong, Jiangsu Patentee after: NANTONG HONGCI PHARMACEUTICAL CO., LTD. Address before: 364300 Longyan City, Fujian Province Qingyun Wuping County Hill Industrial Park 8 Building No. 2 Patentee before: Hu Keding |