CN102357210A - Traditional Chinese medicine composition for curing facial acne - Google Patents

Traditional Chinese medicine composition for curing facial acne Download PDF

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CN102357210A
CN102357210A CN2011103306496A CN201110330649A CN102357210A CN 102357210 A CN102357210 A CN 102357210A CN 2011103306496 A CN2011103306496 A CN 2011103306496A CN 201110330649 A CN201110330649 A CN 201110330649A CN 102357210 A CN102357210 A CN 102357210A
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chinese medicine
acne
medicine composition
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CN102357210B (en
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潘根起
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Abstract

The invention belongs to the technical field of traditional Chinese medicine and particularly discloses a traditional Chinese medicine composition for curing facial acne, which is prepared by the following raw materials by weight: 5-15 parts of root barks of white mulberry, 3-10 parts of burdock, 3-10 parts of cimicifugae foetidae, 10-15 parts of honeysuckle, 3-10 parts of scutellaria baicalensis, 10-30 parts of roots of rehmannia, 5-10 parts of rheum officinale, 3-10 parts of pangolin scales, 3-10 parts of spina gleditsiae, 5-15 parts of roots of red-rooted salvia, 3-9 parts of safflowers, 5-10 parts of rhizoma atractylodis, 10-60 parts of astragalus mongholicus, 5-10 parts of polygala tenuifolia, 10-30 parts of cortex albiziae and 6-15 parts of bamboo leaves. The traditional Chinese medicine composition for curing the facial acne has the functions of freeing lungs, expelling pathogenic factors, detoxicating, invigorating the circulation of blood, detumescence, apocenosis, tonifying spleen and eliminating dampness, not only cures the acne effectively but also enables the acne not to be prone to relapse, resolves the problems of poor effect and repeated relapse when merely western medicine is used for the cure, and brings relief to most young patients.

Description

A kind of Chinese medicine composition of treating facial acne
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Chinese medicine composition of treating facial acne.
Background technology
Facial acne belongs to the category of motherland's medical science " acne "." Yizong Jinjian surgery heart method gist " put down in writing rosacea caused by lung-wind and said: " this disease is formed by the lung meridian heat in blood.Every shape such as broomcorn millet are considered to be worth doing in the broken pimple of face nose, and red complexion swells and ache, and breaks out white lead juice "." General Treatise on the Cause and Symptoms of Diseases " said: " the acne vulgaris person has wind heat gas to give birth to skin ulcer on the meaning face, head as rice are big, and also big like paddy, white person is ".Its pathogenesis is: plain body sun heat is contained partially, the lung meridian intrinsic heat, feels ailment said due to cold or exposure, stifling facial and send out again; Or the pungent delicious food savoury of surfeit, help heat of wetting, damp-heat gluing each other, on steam face and cause; Or insufficiency of the spleen dysfunction of the spleen in transportation and transformation, stop in the turbid damp, strongly fragrant heat-transformation of a specified duration, the bright body fluid of heat is fried in shallow oil and is smelt expectorant, and damp and hot silt expectorant stagnates skin and sends out.Clinically locate to give birth to pimple like thorn with face, breast, the back of the body etc., can extrude the white kind powder juice of cracking rice is principal character.
Facial acne is the chronic inflammatory disease of hair follicle, sebaceous gland, from the beginning of being pinhead-sized hair follicle property pimple, can extrude white or faint yellow fat bolt, and because of infection forms red little pimple, pimple can appear in the top.The severe infections position is darker, aubergine tuberosity, abscess, cyst occur, even ulceration forms cicatrix or is the orange peel change.Primary disease is mainly in the young men and women of adolescence, directly influences appearance and image.And use the western medicine effect not good enough merely, erythra is prone to take place repeatedly, brings very big mental pressure for numerous youth.
Summary of the invention
For overcoming the weak point that exists in the prior art, the object of the present invention is to provide a kind of Chinese medicine composition of treating facial acne.Said composition has the function of the detoxifcation of lung qi dispersing expelling pathogenic factors from the exterior, promoting blood circulation and detumescence evacuation of pus, the spleen strengthening and damp drying.The present composition can effectively be cured acne, makes again to be difficult for recurrence.
For realizing above-mentioned purpose, the technical scheme that the present invention takes is following:
A kind of Chinese medicine composition of treating facial acne is processed by each crude drug of following portions by weight: 5 ~ 15 parts of Cortex Mori, 3 ~ 10 parts of Fructus Arctiis, 3 ~ 10 parts of Rhizoma Cimicifugaes, 10 ~ 15 parts of Flos Loniceraes, 3 ~ 10 parts of Radix Scutellariaes, 10 ~ 30 parts in the Radix Rehmanniae, 5 ~ 10 parts of Radix Et Rhizoma Rhei, 3 ~ 10 parts of Squama Maniss, 3 ~ 10 parts of Spina Gleditsiaes, 5 ~ 15 parts of Radix Salviae Miltiorrhizaes, 3 ~ 9 parts on Flos Carthami, 5 ~ 10 parts of Rhizoma Atractylodis, 10 ~ 60 parts of the Radixs Astragali, 5 ~ 10 parts of Radix Polygalaes, 10 ~ 30 parts of Cortex Albiziaes, 6 ~ 15 parts on Folium Bambusae.
Further, the parts by weight of said each crude drug are preferably:
10 parts of Cortex Mori, 10 parts of Fructus Arctiis, 6 parts of Rhizoma Cimicifugaes, 15 parts of Flos Loniceraes, 10 parts of Radix Scutellariaes, 10 parts in the Radix Rehmanniae, 5 parts of Radix Et Rhizoma Rhei, 6 parts of Squama Maniss, 10 parts of Spina Gleditsiaes, 10 parts of Radix Salviae Miltiorrhizaes, 6 parts on Flos Carthami, 10 parts of Rhizoma Atractylodis, 30 parts of the Radixs Astragali, 10 parts of Radix Polygalaes, 15 parts of Cortex Albiziaes, 6 parts on Folium Bambusae.
Preferably, Squama Manis is a Squama Manis preparata.
Process any acceptable clinically preparation by conventional method, such as can be decoct, pill, capsule, granule or concentrated pill.Can choose and add corresponding conventional adjuvant according to the needs of different preparations.
Method for preparing and method for using:
The PD phase: 1. in by weight/volume; Take by weighing Cortex Mori 5 ~ 15g, Fructus Arctii 3 ~ 10g, Rhizoma Cimicifugae 3 ~ 10g, Flos Lonicerae 10 ~ 15g, Radix Scutellariae 3 ~ 10g, the Radix Rehmanniae 10 ~ 30g, Radix Et Rhizoma Rhei 5 ~ 10g, Squama Manis 3 ~ 10g, Spina Gleditsiae 3 ~ 10g, Radix Salviae Miltiorrhizae 5 ~ 15g, Flos Carthami 3 ~ 9g, Rhizoma Atractylodis 5 ~ 10g, the Radix Astragali 10 ~ 60g, Radix Polygalae 5 ~ 10g, Cortex Albiziae 10 ~ 30g, Folium Bambusae 6 ~ 15g; Then this 16 flavor crude drug is put into marmite; First fries in shallow oil and adds water 600ml and soaked 30 minutes; After boiling with high heat earlier, used the about 350ml of taking liquid again instead 30 minutes at a simmer; Second fries in shallow oil and adds water 500ml, uses the about 350ml of taking liquid again instead 25 minutes at a simmer after boiling with high heat earlier; Two boil medicine liquid mix after clothes at twice, early, evening each clothes once, decoction being taken warmly.Or, 2. utilize prior art to process granule the present invention's 16 flavor crude drug, divide the bag of packing into, every bag of 10g obeys 1 bag at every turn, obeys warm boiled water every day three times.
The stable disease phase: by weight ratio; Take by weighing Cortex Mori 5 ~ 15g, Fructus Arctii 3 ~ 10g, Rhizoma Cimicifugae 3 ~ 10g, Flos Lonicerae 10 ~ 15g, Radix Scutellariae 3 ~ 10g, the Radix Rehmanniae 10 ~ 30g, Radix Et Rhizoma Rhei 5 ~ 10g, Squama Manis 3 ~ 10g, Spina Gleditsiae 3 ~ 10g, Radix Salviae Miltiorrhizae 5 ~ 15g, Flos Carthami 3 ~ 9g, Rhizoma Atractylodis 5 ~ 10g, the Radix Astragali 10 ~ 60g, Radix Polygalae 5 ~ 10g, Cortex Albiziae 10 ~ 30g, Folium Bambusae 6 ~ 15g; Then this 16 flavor Chinese medicine is pulverized the back and cross 120 mesh sieves; After processing superfine medicated powder: 1. medicated powder and honey are processed honeyed pill by the 1:1.5 mass ratio, every ball 3g obeys 6g at every turn; Obey warm boiled water every day three times; Or, 2. with the medicated powder Capsules of packing into, every 0.3g, obey 6, every day three times, warm boiled water at every turn; Or, 3. utilize prior art to process concentrated pill the present invention's 16 flavor crude drug, obey 6g at every turn, obey warm boiled water every day three times.
Pharmacology of the present invention:
Cortex Mori: sweet in the mouth is cold in nature, returns lung meridian, has the effect of eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.These article are cold in nature, aqueous vapor in the eliminating the pathogens from the lung of can clear purte the white holding concurrently and relieving asthma and cough, in all lungs burning hot or aqueous vapor for suffering from, all available it, kind especially clear eliminating the pathogens from the lung heat and spleen insufficiency, water is wet not to be had system and causes disease such as appearance skin edema.Because of lung governing skin and hair, get the toxic swelling of its removing summer-heat face skin.
Fructus Arctii: the acrid in the mouth bitterness is cold, attaches to the lung and stomach meridians, and has dispelling wind and heat pathogens, rash sore-throat relieving, the diffusing swollen effect of detoxifcation.These article are let out clearly and are loose, can dispelling wind and heat pathogens, and expelling heat from the exterior pyretic toxicity and impel measles to pass through and send out with controlling measles without adequate eruption or pass through and multiple latent, and is got the merit that it lets out the poison that dispels the heat clearly.These article of condition again in rise floating among, the property of falling is clearly arranged, the wind heat of loosing outward, in separate pyretic toxicity, attack outward with controlling wind heat, fire-toxin is interior ties diseases such as carbuncle sore tumefacting virus.
Rhizoma Cimicifugae: the acrid-sweet flavor cold nature, return lung, spleen, stomach, large intestine channel, have the effect of the rash of delivering, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.These article can suffering distribute table, and treating measles can be used for controlling measles from the beginning of, pathogenic factor in the exterior external beam, and rash goes out freely not wait disease.These article are good at heat-clearing toxin-expelling functions again, are the good medicine of heat-clearing and toxic substances removing, the available various disease conditions of controlling due to the pyretic toxicity, but the bright pyretic toxicity of kind especially removing summer-heat sun, and face is the Yangming Channel area-covered, it is intended to this.
Flos Lonicerae: sweet in the mouth is cold in nature, returns lung, the heart, stomach warp, has the effect of heat-clearing and toxic substances removing, dispelling wind and heat pathogens.These article sweet in the mouth is cold in nature, both heat-clearing and toxic substances removing, and tool is gently declared the property of evacuation again, and heresy that can the warm epidemic disease poison of removing summer-heat is for treating the key medicine of the positive diseases of all carbuncle furuncle.The disease such as each stage and pyretic toxicity carbuncle sore that can be used for epidemic febrile disease.
Radix Scutellariae: bitter in the mouth is cold in nature, returns lung, stomach, gallbladder, large intestine channel, has effects such as heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis.The kind clear damp-heat in upper-JIAO of these article reaches the merit of stronger eliminating fire and detoxication, is longer than the heat of half exterior and half interior clearly again, can dredge and pass through the outer heresy of going into to lack sun.So except that being used to control disease such as epidemic febrile disease, also be usually used in all diseases of carbuncle.
The Radix Rehmanniae: sweet-bitter flavor is cold in nature, and GUIXIN, liver, lung meridian have the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.These article sweet-bitter flavor is and cold in nature, and kind clearing heat in YING system divides the heresy of blood system.In order to control the warm febrile disease blood of joining the army, the heat in blood poison is contained, the purple black disease of waiting of macule.
Radix Et Rhizoma Rhei: bitter in the mouth is cold in nature, returns spleen, stomach, large intestine, liver, heart channel, has heat and toxic materials clearing away, clearing away heat-fire hemostasis, detoxifcation, the effect of blood circulation promoting and blood stasis dispelling.These article hardship is fallen, can make inflammation the fire under let out.Ability heat-clearing and toxic substances removing for oral administration, detumescence piece, and its relieving constipation by purgation effect of borrowing make under the pyretic toxicity and let out.Other has blood circulation promoting and blood stasis dispelling effect preferably, controls all diseases of pyretic toxicity carbuncle furuncle and swelling and pain due to blood stasis.
Squama Manis: the salty in the mouth cold nature, return liver, stomach warp, have the Xiao of invigorating blood circulation wei, an effect of the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis.This moral character is apt to away scurry, and the stasis of blood of ability promoting the circulation of blood branch stagnates, and the eliminating carbuncle of invigorating blood circulation, detumescence and apocenosis can make not one-tenth person dissipation of pus, and person's speed is burst to have become pus, for treating the key medicine that skin infection swells and ache.The compatibility Radix Astragali, Spina Gleditsiae are passed through inside to strengthen poison holding, promote the merit of skin infection evacuation of pus, can be used for controlling the carbuncle sore tumefacting virus of each phase.
Spina Gleditsiae: acrid in the mouth is warm in nature, has expelling pus and toxin by strengthening QI, the effect of promoting blood circulation and detumescence, be used for skin sore from the beginning of or the disease of difficulty in discharging of pus.
Radix Salviae Miltiorrhizae: the bitter in the mouth cold nature, GUIXIN, Liver Channel have effects such as blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle, relieving restlessness are calmed the nerves, regulating menstruation." merit is the promoting the circulation of blood of invigorating blood circulation to these article, interior reaches internal organs and blood stasis dispelling stagnates, and WEIJIA breaks so gather Xiao; Outer profit joint and the meridian dredging, the then strong and numbness work row of waist knee joint." book on Chinese herbal medicine justice " " its property of medicine is gentle, can promoting tissue regeneration by removing blood stasis, invigorate blood circulation and just do not hinder.Be widely used in the various diseases due to the blood stasis.And can invigorate blood circulation again by removing heat from blood, the merit of stagnant heat subduing inflammation is clearly arranged, can be used for the diseases such as sore and toxic that the resistance of the pyretic toxicity stasis of blood causes.
Flos Carthami: acrid in the mouth is warm in nature, and GUIXIN, Liver Channel have the merit of promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.The hot temperature of loosing of these article is logical, is the key medicine of promoting blood circulation, dredging meridian and relieving pain.And through blood circulation promoting and blood stasis dispelling and Da Xiao wei, unobstructed blood vessels, the effect of reducing swelling and alleviating pain, and the merit of getting its blood circulation promoting and blood stasis dispelling speckle removing are with controlling heat stagnation blood stasis, macule color secretly at disease.
Rhizoma Atractylodis: the bitter tepor of acrid in the mouth, return spleen, stomach warp, have effect drying damp and strengthening spleen, wind-damp dispelling.These article are hot to loose bitter dryly, and kind dry spleen is wet, and diseases such as, vomiting and nausea lack of appetite vexed to the gastral cavity abdominal distention due to the retention of dampness in middle-JIAO are the most suitable, more can be used for damp and hot diseases such as eczema and eczema of accumulateing due to long-pending.These article can make the strong fortune of taste, clear sun rising, the key clearly of supplementing nutrition.So be used for the pungent delicious food savoury of surfeit, help heat of wetting, damp-heat gluing each other, on steam face and the diseases such as acne noxious dampness that cause.
The Radix Astragali: the sweet in the mouth tepor, return spleen, lung meridian, have the effect that spleen reinforcing lung qi, ascending up spleen-Qi and Yang, benefit are defended consolidating superficial resistance, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening, enriched blood and invigorate blood circulation.These article have benefiting vital QI and blood, reinforcing body resistance, with the poison of admitting a child into a nursery school go out, the effect of promoting tissue regeneration and ulcer healing.So availablely control skin infection mid-term, weakened body resistance malicious Sheng can not poison holding reaches outward, skin ulcer shape is flatly collapsed, the base of lesion spread, the difficult difficult rotten person of bursting.In the skin infection later stage, malicious gesture is gone, because of deficient qi and blood, the open sore part difficulty person of holding back.With this article qi and blood tonifying, the effect of eliminating the toxic material out by tonification, promoting tissue regeneration and ulcer healing is arranged.
Radix Polygalae: the hot slightly warm in nature of bitter in the mouth, GUIXIN, kidney, lung meridian have that mind tranquilizing and the heart calming, blood stasis dispelling are had one's ideas straightened out, the effect of dissipation carbuncle.It is logical that these article hardship is let out temperature, and the heap soil or fertilizer over and around the roots that merit is arrogated to oneself promoting flow of QI and blood stagnates and the dissipation carbuncle, treats various skin sore, pays no attention to cold and heat and asthenia and sthenia and all can use, and for oral administration, external all can.
Cortex Albiziae: sweet in the mouth property is flat, and GUIXIN, Liver Channel have the effect of the resolving depression of calming the nerves, promoting blood circulation and detumescence.The sweet suffering of these article is gone into the heart, Liver Channel, can separate stagnation of liver-QI and make the happy and resolving stagnation for tranquilization of the five internal organs peaces and, will, is used for that feelings will is unsuccessful, all diseases due to the anger melancholy more.Other has the merit of promoting blood circulation and detumescence, and inside and outside carbuncle can dissipate.
Folium Bambusae: acrid in the mouth is light cold in nature, and GUIXIN, stomach, small intestine meridian have clearing heat and relieving fidgetness, a function of the diuresis of promoting the production of body fluid.It is cold that these article are done bitterness, can rush down the edema caused by disorder of QI excess-heat clearly, and certain refrigeration function is arranged.Clearing away heart-fire on the ability, following diuresis, the heat that can make the heart and small intestinal is discharged from urine, so availablely control disease such as hyperactivity of heart-fire, its China of the heart is at face again, gets its Folium Bambusae and draws heart channel pathogenic heat and separate from urine.
More than all medicine compatibilities, the effect of playing the detoxifcation of lung qi dispersing expelling pathogenic factors from the exterior, promoting blood circulation and detumescence evacuation of pus, the spleen strengthening and damp drying altogether.The plain body sun of main treatment heat is contained partially, the lung meridian intrinsic heat, feels ailment said due to cold or exposure, stifling facial and send out again; Or the pungent delicious food savoury of surfeit, help heat of wetting, damp-heat gluing each other, on steam face and cause; Or insufficiency of the spleen dysfunction of the spleen in transportation and transformation, stop in the turbid damp, strongly fragrant heat-transformation of a specified duration, the bright body fluid of heat is fried in shallow oil and is smelt expectorant, and damp and hot silt expectorant stagnates skin and sends out; Clinical in diseases such as the living acnes in places such as face, breast, the back of the body.
The present composition can effectively be cured acne, makes again to be difficult for recurrence, has remedied merely with not good enough and the easy drawback of showing effect repeatedly of western medicine effect, brings glad tidings to vast young patient.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is done to introduce in detail further, but protection scope of the present invention is not limited thereto.
Embodiment 1
Cortex Mori 5g, Fructus Arctii 6g, Rhizoma Cimicifugae 3g, Flos Lonicerae 10g, Radix Scutellariae 3g, Radix Rehmanniae 30g, Radix Et Rhizoma Rhei 10g, Squama Manis preparata 10g, Spina Gleditsiae 6g, Radix Salviae Miltiorrhizae 5g, Flos Carthami 9g, Rhizoma Atractylodis 8g, Radix Astragali 10g, Radix Polygalae 5g, Cortex Albiziae 5g, Folium Bambusae 10g.
Method for preparing and method for using:
The PD phase: 1. above-mentioned 16 flavor crude drug are put into marmite, first fries in shallow oil and adds water 600ml and soaked 30 minutes, after boiling with high heat earlier, uses the about 350ml of taking liquid again instead 30 minutes at a simmer; Second fries in shallow oil and adds water 500ml, uses the about 350ml of taking liquid again instead 25 minutes at a simmer after boiling with high heat earlier; Two boil medicine liquid mix after clothes at twice, early, evening each clothes once, decoction being taken warmly.Or, 2. utilize prior art to process granule above-mentioned 16 flavor crude drug, divide the bag of packing into, every bag of 10g obeys 1 bag at every turn, obeys warm boiled water every day three times.
The stable disease phase: above-mentioned 16 flavor Chinese medicines are pulverized the back cross 120 mesh sieves, process superfine medicated powder after: 1. medicated powder and honey are processed honeyed pill by the 1:1.5 mass ratio, every ball 3g obeys 6g, every day at every turn and obeys warm boiled water three times; Or, 2. with the medicated powder Capsules of packing into, every 0.3g, obey 6, every day three times, warm boiled water at every turn; Or, 3. utilize prior art to process concentrated pill the present invention's 16 flavor crude drug, obey 6g at every turn, obey warm boiled water every day three times.
Embodiment 2
Cortex Mori 10g, Fructus Arctii 10g, Rhizoma Cimicifugae 6g, Flos Lonicerae 15g, Radix Scutellariae 10g, Radix Rehmanniae 10g, Radix Et Rhizoma Rhei 5g, Squama Manis preparata 6g, Spina Gleditsiae 10g, Radix Salviae Miltiorrhizae 10g, Flos Carthami 6g, Rhizoma Atractylodis 10g, Radix Astragali 30g, Radix Polygalae 10g, Cortex Albiziae 15g, Folium Bambusae 6g.
Method for preparing and method for using are with embodiment 1.
Embodiment 3
Cortex Mori 15g, Fructus Arctii 3g, Rhizoma Cimicifugae 10g, Flos Lonicerae 13g, Radix Scutellariae 6g, Radix Rehmanniae 15g, Radix Et Rhizoma Rhei 8g, Squama Manis preparata 3g, Spina Gleditsiae 3g, Radix Salviae Miltiorrhizae 15g, Flos Carthami 3g, Rhizoma Atractylodis 5g, Radix Astragali 60g, Radix Polygalae 6g, Cortex Albiziae 30g, Folium Bambusae 15g.
Method for preparing and method for using are with embodiment 1.
Clinical trial
1.1 physical data
From year August in January, 2005 to 2011, accept facial acne patient 110 examples for medical treatment.All cases are all made a definite diagnosis through health check-up and lab testing, and be not in the mood for, liver, the bad person of renal function.Be divided into treatment at random and organize 55 examples, wherein male 32 examples, women 23 examples, 16 ~ 28 years old age, 19 years old mean age; Matched group 55 examples, wherein male 33 examples, women 22 examples, 17 ~ 30 years old age, 21 years old mean age.Two groups are not all had significant difference (P>0.05) at aspects such as sex, age, the state of an illness, have comparability, see table 1 for details.
Figure 960751DEST_PATH_IMAGE001
1.2 diagnostic criteria
1. how to fall ill in adolescence; 2. send out in the red little pimple of face and neck, chest etc., color is red on every side, extrudes grain of rice appearance white fat bolt with finger; 3. how before and after eating and drinking without temperance or women's menstrual phase, to increase the weight of; 4. lab testing routine blood test: leukocyte is normal or higher.
1.3 Therapeutic Method
Matched group: adopt the routine of western medicine treatment: antibiotic is with cefalexin capsule or Amoxicillin Capsules etc., external benzoyl peroxide ointment, other symptomatic treatment.
Treatment group: on the basis of matched group, add the embodiment of the invention 2 prescriptions and preparation method thereof, method for using with the routine of western medicine treatment.
Two groups treated for 4 weeks respectively after, observe facial area skin lesion and clinical symptoms and improve situation.
1.4 therapeutic evaluation
Produce effects: the healing of facial area acne, the red pimple of no New Development, clinical symptom disappearance.
Effectively: the facial area acne heals basically, the red pimple of no New Development, and clinical symptoms disappears basically.
Invalid: as not have obviously change before facial area acne and clinical symptoms and the treatment, still have the red pimple of New Development.
1.5 statistical method
Data are represented with rate, adopt X 2Check is with P<0.05 for difference has statistical significance.
1.6 result
1.6.1 two groups of clinical symptoms improvement situation relatively before and after the treatment
The treatment group is treated on the basis with routine of western medicine at matched group and is added Chinese medicine composition of the present invention, and clinical symptoms improvement rate (92.7%) significantly is superior to matched group merely with routine of western medicine treatment back clinical symptoms improvement rate (58.1%), sees table 2 for details.
Figure 877891DEST_PATH_IMAGE002
1.6.2 untoward reaction
Matched group does not have obvious adverse reaction, but has 23 routine symptoms not have obvious improvement, repeatedly outbreak.The treatment group does not have any obvious adverse reaction, has 3 routine weak curative effect persons to be scar diathesis and has a liking for article of eating pungent delicious food etc. usually.
Model case
Case 1
Shao so-and-so, the woman, 22 years old, the peasant was western Shao Xiang west Shao Ji people from village, on JIUYUE 15th, 2006, came the inventor to locate to go to a doctor with " facial acne ".The patient before 3 years because of repeated cold, cough, pharyngalgia occur, facially red pimple occurs, down here, increase gradually.Through many places treatments, the time heavy when light, outbreak repeatedly, the present closes on wedding day, it is anxious that the patient feels more, and locates so change the inventor over to.Disease is seen: facial area is covered with little abscess rash, and color is red on every side, extrudes grain of rice appearance white fat bolt with finger, and the pain of itching is arranged, thirsty, constipation, red tongue yellow fur, rapid pulse.Routine blood test: WBC 5.0 * 10 9/ L, RBC 4.0 * 10 12/ L, L:37%.
Dialectical Analyses: the plain body sun of patient heat is contained partially, and the lung meridian intrinsic heat so see thirstyly, is felt ailment said due to cold or exposure again, a stifling facial and impetigo.Red tongue yellow fur, rapid pulse are resembling of wind and heat in the lung meridian.
Diagnosis: (facial acne) acne: wind and heat in the lung meridian type.
The rule of treatment: lung qi dispersing expelling pathogenic factors from the exterior, detoxifcation, promoting blood circulation and detumescence evacuation of pus.
Side's medicine: the embodiment of the invention 2 prescriptions and preparation method thereof, method for using.
Western medicine: anti-inflammation is used cefalexin capsule, external benzoyl peroxide ointment, other symptomatic treatment.
After 3 weeks of treatment, it is normal that clinical symptoms such as facial acne disappears basically, and is thirsty is recovered.Advise 2 week of the honeyed pill back recovery from illness that continues to take the embodiment of the invention 2 prescriptions,, do not have recurrence through repeatedly following up a case by regular visits to.
Case 2
Liu so-and-so, the woman, 28 years old, the peasant was north pass people from village, area just outside a city gate town, on JIUYUE 5th, 2007, came the inventor to locate to go to a doctor with " facial acne ".The patient is in over 2 years, and face covers with red little pimple gradually, extrudes grain of rice appearance white fat bolt and heals with finger, and down here, mental pressure is very big.Once cured many places, and poor effect is so change the inventor place over to.Disease is seen: face and jaw red impetigo occurs down, swell and ache, halitosis, constipation, red tongue with yellowish and greasy fur, slippery and rapid pulse.Routine blood test: WBC 7 * 10 9/ L, RBC 4.7 * 10 12/ L, L:40%.
Dialectical Analyses: the patient has a liking for the article of eating pungent delicious food, helps heat of wetting, damp-heat gluing each other, last steaming and cause that face red impetigo occurs, swells and ache, halitosis; Damp and hot tenesmus, impairment of body fluid consumption liquid, so constipation, red tongue with yellowish and greasy fur, slippery and rapid pulse are the damp and hot disease of the intestines and stomach.
Diagnosis: (facial acne) acne: the intestines and stomach damp-heat type.
The rule of treatment: the spleen strengthening and damp drying detoxifcation, detumescence and apocenosis.
Side's medicine: the embodiment of the invention 3 prescriptions and preparation method thereof, method for using.
Western medicine: antibiotic is used the amoxicillin, external benzoyl peroxide ointment, other symptomatic treatment.
After 3 weeks of treatment, facial acne healing, disappearance, halitosis disappears, and stool transfers to normal.Advise 2 week of the honeyed pill back recovery from illness that continues to take the embodiment of the invention 3 prescriptions,, do not have recurrence through repeatedly following up a case by regular visits to.
Case 3
Zhao so-and-so, the man, 19 years old, the student was North Street people from village, area just outside a city gate town, on October 6th, 2009, came the inventor to locate to go to a doctor with " facial acne ".The patient is over 2 years, and face engenders impetigo, and repeated infection is purple dark around the rash, is nodositas individually.Once cure many places, does not prolongedly heal, and locates so change the inventor over to.Disease is seen: facial exanthema vesiculosum, color is purple dark on every side, is nodositas, abdominal distention, indigestion and loss of appetite, dark tongue quality yellow and greasy fur, stringy and rolling pulse individually.Routine blood test: WBC 5 * 10 9/ L, RBC 4.7 * 10 12/ L, L:36%.
Dialectical Analyses: eating and drinking without temperance, impairing the spleen and stomach, dysfunction of the spleen in transportation and transformation so see abdominal distension and anorexia, accumulates in the turbid damp, strongly fragrant heat-transformation of a specified duration, the heat body fluid that burns becomes expectorant, and the damp and hot stasis of blood expectorant skin that stagnates is so meeting portion exanthema vesiculosum, the color purple secretly is nodositas on every side.Dark tongue quality yellow and greasy fur, stringy and rolling pulse are stagnant the resembling of the damp-phlegm stasis of blood.
Diagnosis: (facial acne) acne: damp-phlegm stasis type.
The rule of treatment: expelling pathogenic factors from the exterior detoxifcation, the spleen strengthening and damp drying, promoting blood circulation and detumescence evacuation of pus.
Side's medicine: the embodiment of the invention 1 prescription and preparation method thereof, method for using.
Western medicine: anti-inflammation is used cefalexin capsule, external benzoyl peroxide ointment, other symptomatic treatment.
After 4 weeks of treatment, face simplex disappears, and the surrounding skin purple secretly goes down, and the tuberal part deliquescing diminishes, and abdominal distention disappears, and the appetite amelioration is almost recovered.Advise 4 week of the honeyed pill back recovery from illness that continues to take the embodiment of the invention 1 prescription,, do not have recurrence through repeatedly following up a case by regular visits to.

Claims (5)

1. a Chinese medicine composition of treating facial acne is characterized in that being processed by each crude drug of following portions by weight: 5 ~ 15 parts of Cortex Mori, 3 ~ 10 parts of Fructus Arctiis, 3 ~ 10 parts of Rhizoma Cimicifugaes, 10 ~ 15 parts of Flos Loniceraes, 3 ~ 10 parts of Radix Scutellariaes, 10 ~ 30 parts in the Radix Rehmanniae, 5 ~ 10 parts of Radix Et Rhizoma Rhei, 3 ~ 10 parts of Squama Maniss, 3 ~ 10 parts of Spina Gleditsiaes, 5 ~ 15 parts of Radix Salviae Miltiorrhizaes, 3 ~ 9 parts on Flos Carthami, 5 ~ 10 parts of Rhizoma Atractylodis, 10 ~ 60 parts of the Radixs Astragali, 5 ~ 10 parts of Radix Polygalaes, 10 ~ 30 parts of Cortex Albiziaes, 6 ~ 15 parts on Folium Bambusae.
2. the Chinese medicine composition of treatment facial acne as claimed in claim 1 is characterized in that being processed by each crude drug of following portions by weight: 10 parts of Cortex Mori, 10 parts of Fructus Arctiis, 6 parts of Rhizoma Cimicifugaes, 15 parts of Flos Loniceraes, 10 parts of Radix Scutellariaes, 10 parts in the Radix Rehmanniae, 5 parts of Radix Et Rhizoma Rhei, 6 parts of Squama Maniss, 10 parts of Spina Gleditsiaes, 10 parts of Radix Salviae Miltiorrhizaes, 6 parts on Flos Carthami, 10 parts of Rhizoma Atractylodis, 30 parts of the Radixs Astragali, 10 parts of Radix Polygalaes, 15 parts of Cortex Albiziaes, 6 parts on Folium Bambusae.
3. according to claim 1 or claim 2 the Chinese medicine composition of treatment facial acne, it is characterized in that: Squama Manis is a Squama Manis preparata.
4. according to claim 1 or claim 2 the Chinese medicine composition of treatment facial acne is characterized in that: process any acceptable clinically preparation by conventional method.
5. the Chinese medicine composition of treatment facial acne as claimed in claim 4 is characterized in that: said preparation is decoct, pill, capsule, granule or concentrated pill.
CN2011103306496A 2011-10-27 2011-10-27 Traditional Chinese medicine composition for curing facial acne Expired - Fee Related CN102357210B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104027661A (en) * 2013-03-05 2014-09-10 范德润 Traditional Chinese medicine preparation for treating facial acne

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101224287A (en) * 2007-12-27 2008-07-23 佟家勇 Oral administration Chinese traditional medicine for treating acne and preparing method thereof
CN101584794A (en) * 2008-12-08 2009-11-25 芮育健 Novel method for treating acne through heat clearing and dampness promotion of angelica, flavescent sophora and fresh rehmannia
CN101584771A (en) * 2008-12-18 2009-11-25 芮育健 Novel application for treating acne through heat clearing and dampness removing of Chinese herbal medicaments of angelica, sophora and fresh rehmannia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101224287A (en) * 2007-12-27 2008-07-23 佟家勇 Oral administration Chinese traditional medicine for treating acne and preparing method thereof
CN101584794A (en) * 2008-12-08 2009-11-25 芮育健 Novel method for treating acne through heat clearing and dampness promotion of angelica, flavescent sophora and fresh rehmannia
CN101584771A (en) * 2008-12-18 2009-11-25 芮育健 Novel application for treating acne through heat clearing and dampness removing of Chinese herbal medicaments of angelica, sophora and fresh rehmannia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104027661A (en) * 2013-03-05 2014-09-10 范德润 Traditional Chinese medicine preparation for treating facial acne

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