CN102343010B - Chinese medicinal composition for treating prolapse of lumbar intervertebral disc - Google Patents
Chinese medicinal composition for treating prolapse of lumbar intervertebral disc Download PDFInfo
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- CN102343010B CN102343010B CN201110370071A CN201110370071A CN102343010B CN 102343010 B CN102343010 B CN 102343010B CN 201110370071 A CN201110370071 A CN 201110370071A CN 201110370071 A CN201110370071 A CN 201110370071A CN 102343010 B CN102343010 B CN 102343010B
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Abstract
The invention discloses a Chinese medicinal composition for treating prolapse of lumbar intervertebral disc. The Chinese medicinal composition is prepared from the following bulk pharmaceuticals by weight: 12-26 grams of white paeony root, 5-9 grams of roasted liquoric root, 8-14 grams of prepared common monkshood mother root, 5-9 grams of Chinese ephedra, 15-20 grams of prepared rehmannia rhizome, 3-6 grams of scorpio, 3-6 grams of centipede, 12-25 grams of clematis root, 10-18 grams of twotooth achyranthes root, 10-24 grams of fortune's drynaria rhizome, 9-18 grams of Chinese atractylodes, 6-15 grams of white mustard seed, 15-28 grams of astragalus, 10-15 grams of Chinese angelica, 6-13 grams of pseudo-ginseng, 8-13 grams of hiraute shiny bugleweed herb, 15-26 grams of deer's horn deglued and 10-20 grams of rhizoma corydalis. As proved by clinical test, the Chinese medicinal composition has a remarkable curative effect on prolapse of lumbar intervertebral disc, and the effective rate is over 92 percent.
Description
Technical field
The present invention relates to a kind of medicine of treating prolapse of lumbar intervertebral disc, relate in particular to a kind of Chinese medicine composition of treating prolapse of lumbar intervertebral disc.
Background technology
Prolapse of lumbar intervertebral disc is a kind of because of being weakened body resistance long-pending damage after the regression of lumbar intervertebral disc own, under the various factors effect, causing lumbar intervertebral disc stress balance stable state by the commonly encountered diseases due to breaking.But traditional view thinks that the pathogeny of prolapse of lumbar intervertebral disc is because the spine structure mechanics is changed into main cause and caused, so traditional doctor trained in Western medicine is the pain relieving anti symptom treatment, or relies on surgical operation therapy or traction etc., and therapeutic effect is all undesirable; Traditional Chinese medical science expectant treatment generally adopts the drug for invigorating blood circulation and eliminating stasis treatment, and therapeutic effect is also undesirable.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition of treatment prolapse of lumbar intervertebral disc evident in efficacy.
The pathogeny of prolapse of lumbar intervertebral disc be since body under a variety of causes effect, weakened body resistance long-pending damage, phlegm and blood stasis; Disorder of QI and blood, meridians are not smooth, spasm of muscles and vessels; The fascia dislocation causes lumbar intervertebral disc stress balance stable state and is broken, and card belongs to deficiency in origin and excess in superficiality, simulataneous insufficiency and excessive; The pathogenesis that both included " stagnation of QI and blood may bring about pain " has the pathogenesis of " Rong Ze pain " again.From the state of an illness of prolapse of lumbar intervertebral disc, weakened body resistance long-pending damage causes the degeneration of lumbar intervertebral disc, and the patient all has pain in various degree clinically, and is numb or tangible pressure pain point is arranged, the dim partially or purple tongue of body of the tongue, petechia, and this is levying of the expectorant stasis of blood.From course of disease analysis, patient's medical history is all longer, and prolonged illness certainly will the blood network interruption of service form blood stasis, and the not normal formation expectorant of water liquid metabolism stagnates, and the expectorant stasis of blood occurs for suffering from.From histologic analysis, all there are organic disease in various degree in patient's lumbar intervertebral disc and adjacent tissue, and the hyperemia reflection of these tissues promptly is levying of blood stasis; Vegetation after the hamartoplasia is stagnant the levying of expectorant.Therefore, void, the stasis of blood, expectorant three are run through the overall process of prolapse of lumbar intervertebral disc.The Therapeutic Principle mainly is that tonify deficiency is set upright, and the expectorant stasis of blood is also controlled the QI and blood regulating; Unimpeded meridians promptly improve affected part (lumbar intervertebral disc) microcirculation, eliminate dysbolismus; Reduce outthrust and discharge inflammation-causing substance, eliminate nerve root surrounding tissue edema, dwindle the vertebral pulp volume; Remove nerve compression, repair the affected part damage, thereby recover lumbar intervertebral disc stress balance stable state.
The present invention treats the Chinese medicine composition of prolapse of lumbar intervertebral disc, is formed by following parts by weight of Chinese traditional medicine feedstock production: Radix Paeoniae Alba 12-26g, Radix Glycyrrhizae Preparata 5-9g, Radix Aconiti Preparata 8-14g, Herba Ephedrae 5-9g, Radix Rehmanniae Preparata 15-20g, Scorpio 3-6g, Scolopendra 3-6g, Radix Clematidis 12-25g, Radix Achyranthis Bidentatae 10-18g, Rhizoma Drynariae 10-24g, Rhizoma Atractylodis 9-18g, Semen Sinapis Albae 6-15g, Radix Astragali 15-28g, Radix Angelicae Sinensis 10-15g, Radix Notoginseng 6-13g, Herba Lycopi 8-13g, Cornu Cervi Degelatinatum 15-26g, Rhizoma Corydalis 10-20g.
The raw material of Chinese medicine weight portion proportion optimization scope for preparing Chinese medicine composition of the present invention is: Radix Paeoniae Alba 13-16g, Radix Glycyrrhizae Preparata 6-8g, Radix Aconiti Preparata 9-12g, Herba Ephedrae 6-8g, Radix Rehmanniae Preparata 16-18g, Scorpio 3-5g, Scolopendra 3-5g, Radix Clematidis 15-20g, Radix Achyranthis Bidentatae 10-15g, Rhizoma Drynariae 10-20g, Rhizoma Atractylodis 12-16g, Semen Sinapis Albae 8-12g, Radix Astragali 18-25g, Radix Angelicae Sinensis 10-12g, Radix Notoginseng 8-10g, Herba Lycopi 10-12g, Cornu Cervi Degelatinatum 16-20g, Rhizoma Corydalis 12-18g.
The raw material of Chinese medicine weight portion proportioning the best for preparing Chinese medicine composition of the present invention is: Radix Paeoniae Alba 15g, Radix Glycyrrhizae Preparata 6g, Radix Aconiti Preparata 9g, Herba Ephedrae 6g, Radix Rehmanniae Preparata 17g, Scorpio 3g, Scolopendra 3g, Radix Clematidis 15g, Radix Achyranthis Bidentatae 12g, Rhizoma Drynariae 12g, Rhizoma Atractylodis 12g, Semen Sinapis Albae 10g, Radix Astragali 20g, Radix Angelicae Sinensis 10g, Radix Notoginseng 8g, Herba Lycopi 10g, Cornu Cervi Degelatinatum 18g, Rhizoma Corydalis 14g.
This clearly demarcated Chinese medicine composition can adopt the conventional method for preparing of Chinese medicine to prepare, and promptly through the step of extraction, cryoconcentration, spray drying, granulation, processes for use the getting final product of granule pack.
The Chinese medicine composition that this is clearly demarcated, the Radix Astragali, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Rhizoma Drynariae, Radix Achyranthis Bidentatae benefiting vital QI and blood, bone and muscle strengthening, empty with the treating the liver deficiency of the kidney; Radix Notoginseng, Herba Lycopi, Scorpio, Scolopendra, Radix Clematidis, Semen Sinapis Albae blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, the expectorant diuretic, dredge the meridian passage, power hero and tool is searched the merit of picking is just accord with the pathogenesis of prolonged illness multiple deficiency and stasis excessive phlegm; Radix Aconiti Preparata, Herba Ephedrae, Rhizoma Atractylodis, Radix Glycyrrhizae, Radix Paeoniae Alba relaxing muscles and tendons and activating QI and blood in the collateral, the eliminating impediment pain relieving; Rhizoma Corydalis has analgesic activity; The Cornu Cervi Degelatinatum warming the kidney to activate YANG, astringing to arrest bleeding replenishes the calcareous and aminoacid of human body, improves protein metabolism and improves energy metabolism, increases kidney diuresis function, and enhancing human body immunity power can also promote sclerotin healing, and anti-aging effects is arranged.All medicines share, and expectorant disappears, QI and blood is in harmonious proportion, meridians are dredged freely, thereby improved the affected part microcirculation but then elimnation for excess and tonification for deficiency, the stasis of blood are loose; Eliminate dysbolismus, reduce outthrust and discharge inflammation-causing substance, eliminate nerve root surrounding tissue edema; Dwindle the vertebral pulp volume, remove nerve compression, repair the affected part damage; Recover lumbar intervertebral disc stress balance stable state, all diseases of lower limb skelalgia are eliminated.
Chinese medicine composition of the present invention has significant curative effect through clinical trial to the treatment prolapse of lumbar intervertebral disc, and effective percentage reaches more than 92%.In clinical trial, will be divided into test group and matched group at random through outpatient service and the inpatient that CT makes a definite diagnosis, in test group 546 examples, male 326 examples, women 220 examples, age 24-67 year, average 45 years old, the course of disease 2 week-12 year; In matched group 100 examples, male 57 examples, women 43 examples, 20 years old-61 years old age, average 43 years old, the course of disease 1 week-10 year.Two groups of statistical information there was no significant differences such as patient's sex, age and the course of disease (p>0.05), have comparability.Test one group of 116 example and take the Chinese medicine of the embodiment of the invention 1, one bag of every day (36g); Test two group of 230 example and take the Chinese medicine of the embodiment of the invention 2, one bag of every day (39g); Testing three group of 200 example and take the Chinese medicine of the embodiment of the invention 3, all is branch secondary decoction being taken warmly one bag of every day (46g), promptly adds a little eliminating cold for resuscitation water logging bubble earlier; Add boiled water again to 250-300ml, stir, granule is fully dissolved; Under the clothes, 7 days is a course of treatment, treats 2 courses of treatment altogether.Matched group is taken cloth Lip river branch slow releasing capsule 0.3 according to conventional method, every day 2 times, sooner or later each once, the course of treatment same test group.The curative effect evaluation criteria is: recovery from illness, and the lumbago and skelalgia transference cure, motion is normal, and the neural reflex function is most of to be recovered, and can participate in operate as normal; Effectively, the lumbago and skelalgia transference cure, the neural reflex funtion part is recovered, and can participate in light muscle power work; Invalid, treat 2 courses of treatment after, the lumbago and skelalgia symptom does not alleviate, and does not relatively have obviously change before neural reflex inspection and the treatment.Clinical test results sees the following form:
The specific embodiment
Further specify the present invention through embodiment below, but content of the present invention is not limited only to this:
Embodiment 1
Raw material of Chinese medicine weight portion proportioning: Radix Paeoniae Alba 15g, Radix Glycyrrhizae Preparata 6g, Radix Aconiti Preparata 9g, Herba Ephedrae 6g, Radix Rehmanniae Preparata 17g, Scorpio 3g, Scolopendra 3g, Radix Clematidis 15g, Radix Achyranthis Bidentatae 12g, Rhizoma Drynariae 12g, Rhizoma Atractylodis 12g, Semen Sinapis Albae 10g, Radix Astragali 20g, Radix Angelicae Sinensis 10g, Radix Notoginseng 8g, Herba Lycopi 10g, Cornu Cervi Degelatinatum 18g, Rhizoma Corydalis 14g.
Embodiment 2
Raw material of Chinese medicine weight portion proportioning: Radix Paeoniae Alba 13g, Radix Glycyrrhizae Preparata 9g, Radix Aconiti Preparata 9g, Herba Ephedrae 6g, Radix Rehmanniae Preparata 15g, Scorpio 3g, Scolopendra 3g, Radix Clematidis 15g, Radix Achyranthis Bidentatae 10g, Rhizoma Drynariae 10g, Rhizoma Atractylodis 12g, Semen Sinapis Albae 8g, Radix Astragali 28g, Radix Angelicae Sinensis 10g, Radix Notoginseng 8g, Herba Lycopi 10g, Cornu Cervi Degelatinatum 16g, Rhizoma Corydalis 12g.
Embodiment 3
Raw material of Chinese medicine weight portion proportioning: Radix Paeoniae Alba 26g, Radix Glycyrrhizae Preparata 8g, Radix Aconiti Preparata 12g, Herba Ephedrae 8g, Radix Rehmanniae Preparata 20g, Scorpio 5g, Scolopendra 5g, Radix Clematidis 20g, Radix Achyranthis Bidentatae 15g, Rhizoma Drynariae 20g, Rhizoma Atractylodis 16g, Semen Sinapis Albae 12g, Radix Astragali 15g, Radix Angelicae Sinensis 12g, Radix Notoginseng 10g, Herba Lycopi 12g, Cornu Cervi Degelatinatum 20g, Rhizoma Corydalis 18g.
Claims (3)
1. a Chinese medicine composition of treating prolapse of lumbar intervertebral disc is characterized in that being formed by following parts by weight of Chinese traditional medicine feedstock production: Radix Paeoniae Alba 12-26g, Radix Glycyrrhizae Preparata 5-9g, Radix Aconiti Preparata 8-14g, Herba Ephedrae 5-9g, Radix Rehmanniae Preparata 15-20g, Scorpio 3-6g, Scolopendra 3-6g, Radix Clematidis 12-25g, Radix Achyranthis Bidentatae 10-18g, Rhizoma Drynariae 10-24g, Rhizoma Atractylodis 9-18g, Semen Sinapis Albae 6-15g, Radix Astragali 15-28g, Radix Angelicae Sinensis 10-15g, Radix Notoginseng 6-13g, Herba Lycopi 8-13g, Cornu Cervi Degelatinatum 15-26g, Rhizoma Corydalis 10-20g.
2. a kind of Chinese medicine composition of treating prolapse of lumbar intervertebral disc according to claim 1 is characterized in that being formed by following parts by weight of Chinese traditional medicine feedstock production: Radix Paeoniae Alba 13-16g, Radix Glycyrrhizae Preparata 6-8g, Radix Aconiti Preparata 9-12g, Herba Ephedrae 6-8g, Radix Rehmanniae Preparata 16-18g, Scorpio 3-5g, Scolopendra 3-5g, Radix Clematidis 15-20g, Radix Achyranthis Bidentatae 10-15g, Rhizoma Drynariae 10-20g, Rhizoma Atractylodis 12-16g, Semen Sinapis Albae 8-12g, Radix Astragali 18-25g, Radix Angelicae Sinensis 10-12g, Radix Notoginseng 8-10g, Herba Lycopi 10-12g, Cornu Cervi Degelatinatum 16-20g, Rhizoma Corydalis 12-18g.
3. a kind of Chinese medicine composition of treating prolapse of lumbar intervertebral disc according to claim 1 is characterized in that being formed by following parts by weight of Chinese traditional medicine feedstock production: Radix Paeoniae Alba 15g, Radix Glycyrrhizae Preparata 6g, Radix Aconiti Preparata 9g, Herba Ephedrae 6g, Radix Rehmanniae Preparata 17g, Scorpio 3g, Scolopendra 3g, Radix Clematidis 15g, Radix Achyranthis Bidentatae 12g, Rhizoma Drynariae 12g, Rhizoma Atractylodis 12g, Semen Sinapis Albae 10g, Radix Astragali 20g, Radix Angelicae Sinensis 10g, Radix Notoginseng 8g, Herba Lycopi 10g, Cornu Cervi Degelatinatum 18g, Rhizoma Corydalis 14g.
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| CN201110370071A CN102343010B (en) | 2011-11-21 | 2011-11-21 | Chinese medicinal composition for treating prolapse of lumbar intervertebral disc |
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| CN201110370071A CN102343010B (en) | 2011-11-21 | 2011-11-21 | Chinese medicinal composition for treating prolapse of lumbar intervertebral disc |
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| CN102343010B true CN102343010B (en) | 2012-10-24 |
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| CN103263640A (en) * | 2013-05-23 | 2013-08-28 | 张伯洲 | Traditional Chinese medicine composite for promoting nucleus pulposus retraction and restoring intervertebral disc fiber ring cracking |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1539479A (en) * | 2003-10-30 | 2004-10-27 | 王志臣 | Drug for curing disease of proplapse of lumbar intervertebral disc |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1539479A (en) * | 2003-10-30 | 2004-10-27 | 王志臣 | Drug for curing disease of proplapse of lumbar intervertebral disc |
Non-Patent Citations (2)
| Title |
|---|
| 中医治疗腰椎间盘突出症的近况;何敢;《右江民族医学院学报》;20000229(第2期);301－302 * |
| 何敢.中医治疗腰椎间盘突出症的近况.《右江民族医学院学报》.2000,(第2期),301－302. |
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