CN102342983B - Chinese medicinal composition for treating pain in the legs and numbness of the extremities and preparation method of preparation thereof - Google Patents

Chinese medicinal composition for treating pain in the legs and numbness of the extremities and preparation method of preparation thereof Download PDF

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CN102342983B
CN102342983B CN2011103129504A CN201110312950A CN102342983B CN 102342983 B CN102342983 B CN 102342983B CN 2011103129504 A CN2011103129504 A CN 2011103129504A CN 201110312950 A CN201110312950 A CN 201110312950A CN 102342983 B CN102342983 B CN 102342983B
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pain
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孙丰卿
孙同欣
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Nantong San Intellectual Property Service Co ltd
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Abstract

The invention relates to a Chinese medicinal composition for treating pain in the legs and numbness of the extremities and a preparation method of a preparation thereof. The Chinese medicinal composition comprises the following bulk pharmaceuticals in parts by weight: 25-35 parts of pangolin, 10-20 parts of centipede, 15-25 parts of scorpio, 45-55 parts of szechuan lovage rhizome, 15-25 parts of common monkshood mother root, 45-55 parts of twotooth achyranthes, 25-35 parts of safflower, 35-45 parts of szechwan Chinaberry fruit, 25-35 parts of myrrh, 25-35 parts of liquoric root, 45-55 parts of himalayan teasel root, 45-55 parts of clematis root, 45-55 parts of east asian tree fern rhizome, 45-55 parts of malaytea scurfpea fruit, 45-55 parts of fortune's drynaria rhizome, 45-55 parts of Chinese taxillus twig and 45-55 parts of cortex eucommiae. The preparation method comprises the following steps of: processing the bulk pharmaceuticals in a qualified way; weighing; smashing; sieving; and mixing to obtain medicinal powder. In the Chinese medicinal composition, monarch medicaments, ministerial medicaments, adjuvant medicaments and conductant medicaments play different roles; the Chinese medicinal composition has quick response and a small side effect, and the aims of treating internally and externally and treating both principal and secondary aspects of a disease are fulfilled; and the Chinese medicinal composition has the effects of relieving clinical symptoms of pain in the legs and numbness of the extremities and remarkably shortening the disease course, and has a remarkable treatment effect.

Description

A kind of preparation method for the treatment of the Chinese medicine composition and the preparation thereof of lumbago and skelalgia
Technical field
The present invention relates to a kind of preparation method for the treatment of the Chinese medicine composition and the preparation thereof of lumbago and skelalgia, belong to tcm field.
Background technology
Lumbago and skelalgia has become one of subject matter of puzzlement modern life.Its sickness rate is only second to flu and occupies second.But the disability rate that is caused is but much serious than flu.Epidemiology statistics shows, the light early or late or heavy puzzlement that all is subjected to lumbago and skelalgia of 80% adult.According to how tame hospital statistics, lumbago and skelalgia patient accounts for surgery patient's 30%.The reason of lumbago and skelalgia is a lot, except the only a few patient for acute wound causes, mostly because of due to chronic strain, regression, hypertrophy, the intervertebral disk hernia.Prolapse of lumbar intervertebral disc is the main cause that causes lumbago and skelalgia, and the lumbago and skelalgia that is caused by it accounts for about 10% of whole lumbago and skelalgia cases.Disease such as osteoporosis, tumor of spinal cord also can cause lumbago and skelalgia in addition.Its diseased region is many with soft tissue often, and osteoarthrosis takes second place, and the blood vessel sexually transmitted disease (STD) is then rare.
The cause of disease that causes lumbago and skelalgia has: the other lesion tissue of bone, joint and soft tissue lesions, particularly spinal column and ridge: comprise that acute lumbar muscle sprain, prolapse of lumbar intervertebral disc, derangement of lumbar facet joint, ankylosing spondylitis, lumbar spinal stenosis, fracture dislocation of spine, lumbar vertebrae bone are loose, supraspinal ligament injury, interspinal ligament injury, lumbar muscle strain, myofascitis pain syndrome and lumbar vertebra congenital malformation or the like.The pain that the referred pain of viscera disease and vertebra active chronic inflammation and tumor cause.The psychological disease of spirit is as hysteria and depression.
Motherland's medical science thinks that lumbago and skelalgia diseases caused by exogenous pathogenic factor internal injury all can take place, and it is basis that its pathological change often shows to suffer from a deficiency of the kidney, being invaded by exogenous pathogen, and the tumbling down sprain and contusion are the target characteristics.Meridians are paths of QI-blood circulation, belong to internal organs in it, and outer network is linked up the exterior and the interior, about the perforation in podomere.If meridians are attacked by exopathogen, QI and blood cohesion, the venation of being jammed, stagnation of QI and blood may bring about pain.The Therapeutic Method of primary disease is a lot, and clinical treatment is mainly taken the medicine of nonsteroidal antiinflammatory drug and trophic nerve, but clinical efficacy is poor, and treatment time is long, and side effect is big, and modal is exactly injury of gastrointestinal tract, and, wait characteristics easily repeatedly how not at etiological treatment.
Summary of the invention
At above deficiency, the invention provides a kind of preparation method for the treatment of the Chinese medicine composition and the preparation thereof of lumbago and skelalgia.
Technical scheme of the present invention is as follows:
A kind of Chinese medicine composition for the treatment of lumbago and skelalgia is made by following medical material: Squama Manis 25-35 part, Scolopendra 10-20 part, Scorpio 15-25 part, Rhizoma Chuanxiong 45-55 part, Radix Aconiti 15-25 part, Radix Achyranthis Bidentatae 45-55 part, Flos Carthami 25-35 part, Fructus Toosendan 35-45 part, Myrrha 25-35 part, Radix Glycyrrhizae 25-35 part, Radix Dipsaci 45-55 part, Radix Clematidis 45-55 part, Rhizoma Cibotii 45-55 part, Fructus Psoraleae 45-55 part, Rhizoma Drynariae 45-55 part, parasitic 45-55 part and Cortex Eucommiae 45-55 part.
Further preferred as technique scheme, described Chinese medicine composition is made by following medical material:
30 parts of Squama Manis, 15 parts of Scolopendras, 20 parts of Scorpios, 50 parts of Rhizoma Chuanxiongs, 20 parts of Radix Aconitis, 50 parts of Radix Achyranthis Bidentataes, 30 parts on Flos Carthami, 40 parts of Fructus Toosendans, 30 parts of Myrrhas, 30 parts in Radix Glycyrrhizae, 50 parts of Radix Dipsacis, 50 parts of Radix Clematidis, 50 parts of Rhizoma Cibotii, 50 parts of Fructus Psoraleaes, 50 parts of Rhizoma Drynariae, 50 parts of parasitisms, 50 parts of the Cortexs Eucommiae.
Chinese medicine composition pharmaceutical preparation of the present invention is one of following dosage forms: watered pill, honey pill agent, tablet, capsule or powder.Make by prior art.
A kind of preparation method for the treatment of the Chinese medicine composition pharmaceutical preparation of lumbago and skelalgia may further comprise the steps:
A, get each medicinal ingredient in proportion, concoct, pulverize, cross 80～100 mesh sieves, be mixed into medicated powder by prior art;
B, with the medicated powder of step a general with cold boiled water or Sucus Zingberis be piller, cold drying, packing promptly gets watered pill;
C, get 300 parts of 300 parts of sucrose, 130 parts in water and Mel in addition, mix, refine when relative density is about 1.38 (70 ℃ of mensuration), filter, add the medicated powder mixing of step a, the pill piece is rubbed the ball bar with the hands, the pill grain, and the heavy 9g of every ball promptly gets honey pill agent;
D, the medicated powder of step a is added 125 parts of Mel and an amount of eliminating cold for resuscitation water is made granule, drying adds the moderate lubrication agent by prior art and is pressed into tablet;
E, with add being suitable for adjuvant in the medicated powder of step a, make capsule or powder by prior art.
In above raw material,
The Squama Manis function with cure mainly expel wind to dredge collateral, promoting blood circulation to restore menstrual flow stimulating milk secretion, detumescence and apocenosis.Be used for the Fengshi Guanjie arthralgia pain; , numbness contracture, amenorrhea and mass in the abdomen, galactostasis, carbuncle sore tumefacting virus.
Scolopendra has endogenous wind stopping spasmolytic, dispersing pathogen accumulation, the effect of removing obstruction in the collateral to relieve pain.Be mainly used in the tic spasm, middle air port, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, infantile convulsion, cards such as venom.
The Scorpio function with cure mainly endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Control infantile convulsion and take out and pluck, epilepsy, apoplexy, hemiplegia, facial hemiparalysis, migraine, rheumatic arthralgia, tetanus, tuberculous lymphadenitis, the rubella skin ulcer is swollen, skin infection, scrofula.
The Rhizoma Chuanxiong activating QI to alleviate the depression, the method wind-dryness is wet, promoting blood circulation and stopping pain.Dispelling the wind and dampness pathogens arthralgia pain tumbling and swelling, air-cooled headache is revolved dizzy, and the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Be used for menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body.
The Radix Aconiti function with cure mainly expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
The Radix Achyranthis Bidentatae function with cure mainly eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Be used for amenorrhea and mass in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.
The Flos Carthami function with cure mainly promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Be used for amenorrhea, dysmenorrhea, lochia is not all right, the abdominal mass mass in the abdomen, injury from falling down, skin infection swells and ache.
The Fructus Toosendan function with cure mainly the soothing liver-QI promoting the circulation of QI to relieve pain.Be used for the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation, anthelmintic.
The Myrrha effect blood blood stasis removing that looses, subduing swelling and relieving pain.Cure mainly traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Radix Glycyrrhizae attending effectiveness invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The Radix Dipsaci merit is in invigorating the liver and kidney, bone and muscle strengthening, and blood circulation regulating ends metrorrhagia. cure mainly back acid carbuncle, the podomere flaccidity syndrome and arthralgia syndrome, muscle folding bone is decreased in the tumbling down damage, and fetal movement is leaked red, metrorrhagia hematochezia, seminal emission, leukorrhagia. and the carbuncle skin ulcer is swollen.
The Radix Clematidis function with cure mainly expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Be used for rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone choke with sobs larynx,
The invigorating the liver and kidney of Rhizoma Cibotii attending effectiveness, strong waist knee joint, wind-damp dispelling.Be used for soreness of the waist and knees, weakness of the lower extremities, rheumatic arthralgia.
The Fructus Psoraleae function cures mainly has the kidney warming controlling nocturnal emission with astringent drugs, warm spleen antidiarrheal, the effect of helping inspiration to relieve asthma; Cure mainly insufficiency of kidney-YANG, chills and pain of the waist and kness, impotence and premature ejaculation, emission and spermatorrhea, frequent urination and enuresis; Deficiency of spleen-YANG and kidneyYANG, the stool chronic diarrhea; Failure of the kidney in receiving QI, deficiency and coldness are breathed heavily and are coughed; Vitiligo, alopecia areata.
The Rhizoma Drynariae function cures mainly the kidney invigorating bone strengthening, continues to hinder pain relieving.Be used for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, and the muscles and bones folding is hindered; The external treatment alopecia areata, vitiligo.
The effect of the Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Control the spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is desired to fall, frequent fetal movement, hypertension.
The invigorating the liver and kidney of Herba Taxilli attending effectiveness, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.Be used for rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and the metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement; Hypertension.
It is basis that its pathological change of lumbago and skelalgia often shows to suffer from a deficiency of the kidney, being invaded by exogenous pathogen, and internal injury, the tumbling down sprain and contusion are the target characteristics.Point out just as " miscellaneous diseases source and course rhinoceros candle ": " suffer from a deficiency of the kidney, it also; Wind, cold, wet, heat, phlegm retention, the stagnation of QI, blood stasis, sprain and contusion, it marks also.Or from mark, or from this, your nothing is lost it should." time, QI-blood circulation more stagnated more for a long time, the meridians that stagnate, stagnation of QI and blood may bring about pain.
Fructus Psoraleae, Radix Dipsaci, the sweet temperature of Rhizoma Drynariae are gone into the Liver and kidney warp among the present invention, and warming and recuperating the kidney-YANG is arranged, bone and muscle strengthening, and the merit that benefit is deficient, the double toil of Radix Dipsaci flavor has the promoting the circulation of blood arteries and veins, the effect of reducing swelling and alleviating pain simultaneously.The hot temperature of loosing of Myrrha is logical, blood-activating and qi-promoting, and pain relieving can be stretched muscle again and be exempted from the numbness blood circulation promoting and blood stasis dispelling.The deficiency of the Cortex Eucommiae, Rhizoma Cibotii, parasitic sweet temperature compensation Liver and kidney, strong waist knee joint, wind-damp dispelling.Squama Manis, Scolopendra, the pain relieving of Scorpio expel wind to dredge collateral, promoting blood circulation to restore menstrual flow, compatibility Radix Glycyrrhizae cushion toxicity, strong.The Radix Aconiti expelling wind and removing dampness, antalgic.Rhizoma Chuanxiong, the soothing the liver promoting QI circulation for relieving depression of Fructus Toosendan, promoting blood circulation and stopping pain.The Radix Achyranthis Bidentatae tonifying liver and kidney and strengthening bones and muscles, the sharp joint of promoting blood circulation, priming is descending, Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.The Radix Clematidis expelling wind and removing dampness, removing obstruction in the collateral to relieve pain is alleviated muscle arteries and veins contracture.All medicines share, and logical benefit is helped mutually, treating both the principal and the secondary aspects of a disease at the same time.We have the absorption that promotes congestion, alleviate the elimination edema.The energy microcirculation improvement changes hemorheology and hemodynamic state, thereby reduces intra-osteal pressure, increases the oxygen confession, and lumbar vertebra body bone marrow inner acidic metabolite is reduced, and improves the lumbar intervertebral disc nutrient environment indirectly, the inhibition bone degeneration.
The present invention compared with prior art has the following advantages: monarch of the present invention, minister, help, make and respectively execute its effect, have the medication instant effect, side effect is little, can reach inside and outside and execute the purpose of giving consideration to both the incidental and fundamental.Can suppress the development of the state of an illness, alleviate clinical symptoms, and can obviously shorten the course of disease, therapeutic effect is obvious, is worthy of popularization.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment 1:
A kind of Chinese medicine composition for the treatment of lumbago and skelalgia, described medicine is made by following medical material: 45 parts of 25 parts of Squama Manis, 10 parts of Scolopendras, 15 parts of Scorpios, 45 parts of Rhizoma Chuanxiongs, 15 parts of Radix Aconitis, 45 parts of Radix Achyranthis Bidentataes, 25 parts on Flos Carthami, 35 parts of Fructus Toosendans, 25 parts of Myrrhas, 25 parts in Radix Glycyrrhizae, 45 parts of Radix Dipsacis, 45 parts of Radix Clematidis, 45 parts of Rhizoma Cibotii, 45 parts of Fructus Psoraleaes, 45 parts of Rhizoma Drynariae, parasitic 45 parts and the Cortexs Eucommiae.
The preparation method of described Chinese medicinal composition preparation may further comprise the steps:
A, get each medicinal ingredient in proportion, concoct, pulverize, cross 80～100 mesh sieves, be mixed into medicated powder by prior art;
B, with the medicated powder of step a general with cold boiled water or Sucus Zingberis be piller, cold drying, packing promptly gets watered pill;
C, get 300 parts of sucrose in addition, 300 parts of 130 parts in water and Mel mix, and refine when relative density is about 1.38 (70 ℃ of mensuration), filter, and add the medicated powder mixing of step a, and the pill piece is rubbed the ball bar with the hands, the pill grain, and the heavy 9g of every ball promptly gets honey pill agent;
D, the medicated powder of step a is added 125 parts of Mel and an amount of eliminating cold for resuscitation water is made granule, drying adds the moderate lubrication agent by prior art and is pressed into tablet;
E, with add being suitable for adjuvant in the medicated powder of step a, make capsule, powder by prior art.
Embodiment 2:
A kind of Chinese medicine composition for the treatment of lumbago and skelalgia, described medicine is made by following medical material: 35 parts of Squama Manis, 20 parts of Scolopendras, 25 parts of Scorpios, 55 parts of Rhizoma Chuanxiongs, 25 parts of Radix Aconitis, 55 parts of Radix Achyranthis Bidentataes, 35 parts on Flos Carthami, 45 parts of Fructus Toosendans, 35 parts of Myrrhas, 35 parts in Radix Glycyrrhizae, 55 parts of Radix Dipsacis, 55 parts of Radix Clematidis, 55 parts of Rhizoma Cibotii, 55 parts of Fructus Psoraleaes, 55 parts of Rhizoma Drynariae, 55 parts of parasitisms, 55 parts of the Cortexs Eucommiae.
Preparation method is with embodiment 1.
Embodiment 3:
A kind of Chinese medicine composition for the treatment of lumbago and skelalgia, described medicine is made by following medical material: 30 parts of Squama Manis, 15 parts of Scolopendras, 20 parts of Scorpios, 50 parts of Rhizoma Chuanxiongs, 20 parts of Radix Aconitis, 50 parts of Radix Achyranthis Bidentataes, 30 parts on Flos Carthami, 40 parts of Fructus Toosendans, 30 parts of Myrrhas, 30 parts in Radix Glycyrrhizae, interrupted 50 parts, 50 parts of Radix Clematidis, 50 parts of Rhizoma Cibotii, 50 parts of Fructus Psoraleaes, 50 parts of Rhizoma Drynariae, parasitic 50 parts, 50 parts of the Cortexs Eucommiae.
Preparation method is with embodiment 1.
Contrast test: criterion of therapeutical effect: draft recovery from illness with reference to " disease of tcm diagnosis criterion of therapeutical effect ": the straight lower limb of lumbago and skelalgia transference cure is raised more than 70 ℃, can recover operate as normal and take a turn for the better: lumbago and skelalgia alleviate the waist movable function improve invalid: symptom and sign does not have obvious improvement
Choose 400 routine lumbago and skelalgia patients (comprising prolapse of lumbar intervertebral disc, bulging, sciatica, old lumbar degenerative pathological changes, the lumbar vertebra hyperosteogeny patient), picked at random 300 examples are organized as treatment, other 100 examples are organized in contrast, wherein 300 routine patients are divided into treatment group 1, treatment group 2 and treatment group 3,100 routine patients of each treatment group treatment picked at random, treatment group 1 uses the honey pill agent of the embodiment of the invention 1 preparation to treat, and treatment group 2 uses the honey pill agent of the embodiment of the invention 2 preparations to treat, treatment group 3 uses the honey pill agent of the embodiment of the invention 3 preparations to treat, each 9g, every day 2 times, 15 days is a course of treatment.
The patient of matched group adopts intramuscular injection vitamin B1 and vitamin B12 to add oral Dicolfanac Sodium Sustained Release Tablets and treats.
Therapeutic outcome such as following table:
The contrast group Cure Take a turn for the better (example) Invalid (example) Cure rate Effective percentage
Treatment group 1 71 16 13 71％ 87％
Treatment group 2 75 16 9 75％ 91％
Treatment group 3 81 13 6 81％ 94％
Matched group 63 14 23 63％ 77％
From above tables of data as can be seen, 3 nonresponders are organized in treatment 15 of 6 examples, accounts for 6%, and 13 examples of improvement account for 13%, and healing person's 81 examples account for 81%, and total effective 94%.The matched group nonresponder has 23 examples, accounts for 23%, and 14 examples of improvement account for 14%, and healing person's 63 examples account for 63%, and is total effective 77%.Treatment group effective percentage cure rate is apparently higher than matched group, and the cure rate effective percentage of treatment group 3 is higher than all the other treatment groups 1 and treatment group 2, and to organize 3 prescriptions the most effective in treatment in sum.

Claims (1)

1. a Chinese medicine composition for the treatment of lumbago and skelalgia is characterized in that being made by following medicinal materials in part by weight: 30 parts of Squama Manis, 15 parts of Scolopendras, 20 parts of Scorpios, 50 parts of Rhizoma Chuanxiongs, 20 parts of Radix Aconitis, 50 parts of Radix Achyranthis Bidentataes, 30 parts on Flos Carthami, 40 parts of Fructus Toosendans, 30 parts of Myrrhas, 30 parts in Radix Glycyrrhizae, 50 parts of Radix Dipsacis, 50 parts of Radix Clematidis, 50 parts of Rhizoma Cibotii, 50 parts of Fructus Psoraleaes, 50 parts of Rhizoma Drynariae, 50 parts of parasitisms, 50 parts of the Cortexs Eucommiae.
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CN102670886B (en) * 2012-05-18 2013-09-11 仲崇华 Traditional Chinese medicine for treating sciatica
CN103316227A (en) * 2013-07-01 2013-09-25 郑福来 Medicine composition for treating rheumatic diseases in muscles and bones and preparation method thereof
CN104398698A (en) * 2014-11-12 2015-03-11 崔新明 Traditional Chinese medicine composition for treating meniscus injury
CN106266934A (en) * 2016-06-14 2017-01-04 梁万波 A kind of Chinese medicine composition treating neck, shoulder, waist and leg pain and capsule and preparation method

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License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Jingxuan Textile Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048319

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231127

Application publication date: 20120208

Assignee: Nantong Huanlian Textile Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048315

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231127

Application publication date: 20120208

Assignee: Nantong Huase Space Textile Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048606

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Anergu New Material Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048605

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Laiou Electronic Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048604

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Yitong Intelligent Control Technology (Nantong) Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048603

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Ouchen Electronic Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048602

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Laishang Electronic Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048601

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Lingde Pharmaceutical Equipment Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048600

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Chujie Electronic Equipment Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048597

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Jiaerjie Labor Care Products Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048596

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: JIANGSU KANGFEITE POWER TECHNOLOGY Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048594

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Tuoerpu Surveying and Mapping Information Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048583

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong TongZhou Jinfeng Textile Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048582

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Weiai Home Textile Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048563

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Qiju Textile Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048556

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Juguang Trading Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048551

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Chenghui Pharmacy Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048548

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Tongzhou Kangxintang Drugstore Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048542

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Tuanpinhui E-commerce Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048537

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Koushun E-commerce Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048506

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Tuoda Machinery Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048494

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Weizhi New Material Technology (Nantong) Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048487

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: NANTONG FEIHAI ELECTRONIC TECHNOLOGY CO.,LTD.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048483

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Haoshi new material technology Nantong Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048475

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: Nantong Steel Machinery Manufacturing Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048466

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231128

Application publication date: 20120208

Assignee: NANTONG YUQI METAL PRODUCTS Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048459

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: NANTONG KYLIN MACHINERY LTD.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048456

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: NANTONG LILIAN MACHINE TOOL MANUFACTURING CO.,LTD.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048450

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Yuma Electromechanical Manufacturing Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048446

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Dongdong Steel Structure Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048444

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Huaxin Price Evaluation Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048443

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Yaocheng mechanical equipment manufacturing Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048440

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

Application publication date: 20120208

Assignee: Nantong Xinxin Pharmaceutical Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048425

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231129

EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20120208

Assignee: Nantong Yijialai Woolen Knitting Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980049377

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: NANTONG BEITE PHARMACEUTICAL MACHINERY Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980049199

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: NANTONG HAIGUO MACHINERY Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980049196

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: Nantong Qiaojiang packaging materials Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980049191

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: Nantong Bairun Catering Management Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980049185

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: Nantong Nongchaoer Food Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048976

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: Xingren Tank Farm of Nantong Xinhai Liquefied Gas Service Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048969

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: NANTONG SHUANGHE FOOD Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048967

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: Jiangsu guanan electromechanical Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048961

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: Nantong Runyuan structural parts Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048952

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231203

Application publication date: 20120208

Assignee: Nantong Jinbao Machinery Manufacturing Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048947

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231202

Application publication date: 20120208

Assignee: Nantong Juntai motor vehicle testing Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048942

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231202

Application publication date: 20120208

Assignee: Honglei mechanical equipment (Nantong) Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048782

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231202

Application publication date: 20120208

Assignee: American Antelope Home Textile (Nantong) Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048774

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231202

Application publication date: 20120208

Assignee: Nantong Ansheng Textile Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048765

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231130

Application publication date: 20120208

Assignee: NANTONG YA TAI CANDLE ARTS & CRAFTS Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048764

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231130

Application publication date: 20120208

Assignee: Nantong Jianwei Metal Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048759

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231202

Application publication date: 20120208

Assignee: JIANGSU YATAI FITNESS CO.,LTD.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980048748

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231202

EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20120208

Assignee: Nantong Zhili Machinery Technology Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2023980049698

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20231205

EE01 Entry into force of recordation of patent licensing contract
OL01 Intention to license declared
OL01 Intention to license declared
EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20120208

Assignee: JIANGSU HAOHAN INFORMATION TECHNOLOGY Co.,Ltd.

Assignor: Nantong San Intellectual Property Service Co.,Ltd.

Contract record no.: X2024980003183

Denomination of invention: A traditional Chinese medicine combination and its preparation method for treating lower back and leg pain

Granted publication date: 20130731

License type: Common License

Record date: 20240322