CN102342522B - Health food - Google Patents
Health food Download PDFInfo
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- CN102342522B CN102342522B CN201110256063.XA CN201110256063A CN102342522B CN 102342522 B CN102342522 B CN 102342522B CN 201110256063 A CN201110256063 A CN 201110256063A CN 102342522 B CN102342522 B CN 102342522B
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- health food
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- aweto
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Abstract
The invention belongs to the technical field of health food; the invention discloses health food; the health food raw materials comprise aweto extracts and mineral matter, wherein the aweto extracts account for 10-100 parts by weight, and the mineral matter accounts for 0.05-50 parts by weight. Through research for several years and based on modern medical theory, the applicant finds that the combination of substances such as aweto extracts and mineral matter has very good health care effect; through pharmacological experiment for immunity improvement, the invention determines that substancessuch as aweto extracts and mineral matter have very good synergistic effect, and have better pharmacological effect than single use of aweto.
Description
Technical field
The invention belongs to the medicines and health protection food technology field, be specifically related to the health food that a kind of raw material comprises Cordyceps and mineral matter.
Background technology
Health food is a kind of food, has the general character of normal food, and the function of energy balance the body is suitable for specific crowd edible, but can not treats disease.The growth rate of in recent years countries in the world health food development is all very fast, and health care (function) food is called as " healthy food " in European and American countries, be called as in Japan " functional food ".The rise of China's health care (function) food is at beginning of the nineties late 1980s, development through one, two generations, also will march toward the third generation, be that health food not only needs human body and zoopery to prove that this product has a certain physiological regulation function, more need find out structure, content, the mechanism of action and due stable form in food with this health factor.
Chinese caterpillar fungus claims again Cordyceps sinensis, CORDYCEPS etc.The bacterium worm combination that the fungi of Clavicipitaceae (Cordyceps Militaris) and bat moth larvae form under specific condition, stroma goes out head, the Dan Sheng, elongated such as baseball rod of larva, long 4-11cm.Cordyceps sinensis is the famous precious Chinese medicine of China, TCM Literature think Cordyceps sinensis distinguish the flavor of sweet warm in nature, the effect that secret lean gas is arranged, protect lung kidney tonifying, hemostasis and phlegm.The modern medicine clinical research shows, the diseases such as Cordyceps sinensis can treat that phthisical cough phlegm blood, night sweat, impotence, seminal emission, jaundice are sick, pulmonary tuberculosis and old weak, chronic cough and asthma have strong taking in concurrently to hold back calm effect.
Cordyceps sinensis is the famous precious Chinese medicine of China, therefore, its research and development are the emphasis of healthcare field always, existing bibliographical information a large amount of exploitations about Cordyceps sinensis, health food take Cordyceps sinensis as raw material on the market is also very many, therefore, how Cordyceps sinensis is carried out deep development significant.
Summary of the invention
For these reasons, the scientific research personnel of our company is through for many years research, take modern medical theory as the basis, find Cordyceps (one or more in Cordyceps sinensis polysaccharide, cordycepin, the cordycepic acid), mineral matter, add or do not add collagen polypeptide etc., have the effect of good health care after the combination, the present invention determines by pharmacological testing, the material such as Cordyceps and mineral matter has good synergy, has better pharmacological action than independent use Cordyceps sinensis.
The present invention is achieved through the following technical solutions.
A kind of health food, healthy food material are Cordyceps and mineral matter, and wherein Cordyceps comprises the 10-100 weight portion, mineral matter 0.05-50 weight portion.
Above-mentioned Cordyceps refers to one or more of Cordyceps sinensis polysaccharide, cordycepin, cordycepic acid.Cordyceps is natural cs extract or ferment cordyceps sinensis bacterium powder extracts.
Mineral matter described above is one or more of calcium, chromium, cobalt, copper, fluorine, iodine, iron, boron, magnesium, manganese, molybdenum, phosphorus, potassium, sodium, selenium, sulphur, vanadium, zinc, chlorine or the compound that contains mentioned component.
Above-mentioned healthy food material also comprises Fructus Corni, frutus cnidii, the Radix Astragali, barrenwort, Psoralea corylifolia, the tuber of dwarf lilyturf, the rhizome of davallia, the root of kudzu vine, the red sage root, saline cistanche, glutinous rehmannia, the bark of eucommia, saline cistanche, teasel root, Bailey Myospalax Born, or the extract of above-mentioned Chinese medicine, one or more 1000-5000 weight portions of collagen polypeptide, Glucosamine.
Above-mentioned health food has pharmacological actions such as improving immunity, antiviral, anti-inflammation.
Above-mentioned health food is oral formulations.
Oral formulations described above is tablet, pill, capsule or oral liquid.
Above-mentioned health food is beverage.
One, pharmacological test example
Test 1
Improve immunity function experiment 1
Experimental animal: the female small white mouse of Kunming kind, body weight 18-22g.
Trial drug:
Test 1 group: Cordyceps sinensis.
Test 2 groups: cordycepin.
Test 3 groups: cordycepin 10mg, mineral calcium 0.03mg, magnesium 0.01mg, iron 0.01mg.
Test 4 groups: Cordyceps sinensis polysaccharide 50mg, cordycepic acid 50mg, mineral matter 50mg (calcium 10mg, magnesium 10mg, iron 3mg, zinc 5.5mg, manganese 1mg, selenium 9.5mg, cobalt 0.5mg, molybdenum 10.5mg).
Test 5 groups: cordycepin 20mg, cordycepic acid 20mg, Cordyceps sinensis polysaccharide 35mg, mineral matter 4mg (calcium 2mg, magnesium 1mg, iron 0.5mg, molybdenum 0.5mg), collagen polypeptide 2g.
Test method: get the mouse random packet: blank group, trial drug group, mouse gastric infusion every day 1 time, each dosage is 1g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
Mouse delayed allergy (DTH) was measured: in gavage the 26th day, inject 2% sheep red blood cell (SRBC) (SRBC) 0.2m l/ to mouse peritoneal and only carry out sensitization, the 4th day left back toe ring of every mouse hypodermic injection 20%SRBC of section after immunity (20 μ l/ only) attacks.And 24h measures the same position of the left back sufficient intestines of every mouse thickness before attacking and after attacking, and calculates and attacks forward and backward difference, carries out variance analysis.
Result of the test sees Table 1.
Table 1 pair mouse DTH measurement result (24h)
Annotate: compare * * P＜0.01, * P＜0.05 with control group; Compare #P＜0.05 with 2 groups of tests; Compare △ P＜0.05 with 4 groups of tests.
2, improve immunity function experiment 2
Trial drug:
Test 1 group: Cordyceps sinensis.
Test 2 groups: Cordyceps sinensis polysaccharide.
Test 3 groups: Cordyceps sinensis polysaccharide 15mg, mineral calcium 35mg.
Test 4 groups: cordycepic acid 60mg, mineral matter 25mg (magnesium 5mg, iron 5mg, zinc 2mg, manganese 3mg, cobalt 4mg, chromium 6mg), collagen polypeptide 1g.
Test 5 groups: cordycepin 15mg, Cordyceps sinensis polysaccharide 55mg, mineral matter 18mg (zinc 5.3mg, selenium 4.5mg, cobalt 0.2mg, chromium 5mg, molybdenum 0.3mg), collagen polypeptide 8.5g.
Test method: get the mouse random packet: blank group, trial drug group, mouse gastric infusion every day 1 time, testing 1 group is 1g/kg to testing 4 groups of each dosages, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
ConA inducing mouse SPL transformation experiment (mtt assay): to the aseptic spleen of getting of each group mouse, splenocyte suspension processed, adjusting splenocyte concentration with RPMI 1640 complete culture solutions is 3 * 10
9Individual/L, carry out lymphproliferation response according to MTr method in the program, survey its absorbance (A) at 752-C ultraviolet-uisible spectrophotometer 570nm wavelength place at last, calculate ConA
+With ConA
-The absorbance value difference in each hole.Carry out variance analysis.Result of the test sees Table 2.
Table 2 pair mouse spleen lymphocyte conversion test is measurement result (24h) as a result
Annotate: compare * * P＜0.01, * P＜0.05 with control group; Compare #P＜0.05 with 2 groups of tests; Compare △ P＜0.05 with 3 groups of tests.
Test 3
Improve immunity function experiment 3
Trial drug:
Test 1 group: Cordyceps sinensis.
Test 2 groups: cordycepic acid.
Test 3 groups: Cordyceps sinensis polysaccharide 25mg, mineral matter magnesium 0.03mg, iron 0.015, zinc 0.005mg, collagen polypeptide 2g.
Test 4 groups: cordycepin 100mg, mineral matter 10mg (magnesium 2mg, iron 4mg, zinc 0.9mg, manganese 0.1mg, selenium 0.1mg, cobalt 0.9mg, chromium 0.5mg, molybdenum 1.5mg), collagen polypeptide 7g.
Test 5 groups: cordycepic acid 60mg, mineral matter 5.5mg (calcium 3mg, magnesium 1mg, iron 1mg, molybdenum 0.5mg), Radix Astragali 3g.
Experimental animal: the female small white mouse of Kunming kind, body weight 18-22g.
Test method: get the mouse random packet: blank group, trial drug group, mouse gastric infusion every day 1 time, each dosage is 1.5g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
Serum hemolysin is measured: in gavage the 25th day to mouse peritoneal injection 2%SRBC (0.2ml/ only), after immunity, plucked the eyeball blood sampling on the 5th day, separation of serum and at the clear hemolysin test of the enterprising promoting circulation of blood of Microhemagglutination plate: hatch 3h for 37 ℃, statistics hemagglutination degree calculates the corresponding antibodies product.Carry out variance analysis.Result of the test sees Table 3.
Table 3 couple mice serum hemolysin test result
Annotate: compare * * P＜0.01, * P＜0.05 with control group; Compare △ P＜0.05 with 2 groups of tests.
Two, Preparation Example
Embodiment 1
A kind of health food, healthy food material are cordycepin 10mg, mineral calcium 0.03mg, magnesium 0.01mg, iron 0.01mg.
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 2
A kind of health food, healthy food material are Cordyceps sinensis polysaccharide 30mg, cordycepin 30mg, cordycepic acid 40mg, mineral matter 50mg (calcium 5mg, magnesium 5mg, iron 15.25mg, zinc 2.5mg, manganese 5mg, selenium 4.75mg, cobalt 2.5mg, chromium 5mg, molybdenum 5mg).
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 3
A kind of health food, healthy food material are cordycepic acid 50mg, mineral matter 4mg (calcium 2mg, magnesium 1mg, iron 0.5mg, molybdenum 0.5mg), red sage root 4g.
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 4
A kind of health food, healthy food material are Cordyceps sinensis polysaccharide 25mg, mineral calcium 0.1mg, dwarf lilyturf tuber total saponins 300mg.
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 5
A kind of health food, healthy food material are cordycepin 40mg, Cordyceps sinensis polysaccharide 25mg, mineral matter 5mg (magnesium 1mg, iron 1mg, zinc 0.5mg, manganese 0.99mg, cobalt 0.51mg, chromium 1mg).
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 6
A kind of health food, healthy food material are cordycepic acid 30mg, mineral matter 1.8mg (zinc 0.5mg, selenium 0.48mg, cobalt 0.02mg, chromium 0.5mg, molybdenum 0.3mg), collagen polypeptide 3g, Glucosamine 1g.
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 7
A kind of health food, healthy food material are Cordyceps sinensis polysaccharide 10mg, mineral matter iron 0.1mg, barrenwort 3g, Psoralea corylifolia 2g,, root of kudzu vine 1g, red sage root 2g,, saline cistanche 0.5g, teasel root 1g, Bailey Myospalax Born 1g.
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 8
A kind of health food, healthy food material are cordycepin 55mg, mineral matter 5mg (magnesium 0.5mg, iron 1.5mg, zinc 0.5mg, manganese 0.5mg, cobalt 1mg, chromium 1mg).
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 9
A kind of health food, healthy food material are cordycepin 75mg, mineral matter 4.5mg (calcium 3mg, zinc 0.5mg, selenium 0.45mg, cobalt 0.05mg, chromium 0.5mg).
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 10
A kind of health food, healthy food material are cordycepic acid 35mg, cordycepin 35mg, mineral matter magnesium 0.035mg, iron 0.01, zinc 0.005mg, frutus cnidii 2g, Glucosamine 35mg.
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 11
A kind of health food, healthy food material are cordycepin 100mg, mineral matter 10mg (magnesium 2mg, iron 4mg, zinc 0.9mg, manganese 0.1mg, selenium 0.1mg, cobalt 0.9mg, chromium 1.5mg, molybdenum 1.5mg).
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Embodiment 12
A kind of health food, healthy food material are cordycepin 60mg, mineral matter 5.5mg (calcium 3mg, magnesium 1mg, iron 1mg, molybdenum 0.5mg).
Above-mentioned health food is prepared into oral formulations; Oral formulations is tablet, pill, capsule or oral liquid.
Above-mentioned health food is prepared into beverage.
Claims (5)
1. a health food is characterized in that the health food active component consists of: cordycepin 20mg, cordycepic acid 20mg, Cordyceps sinensis polysaccharide 35mg, calcium 2mg, magnesium 1mg, iron 0.5mg, molybdenum 0.5mg, collagen polypeptide 2g.
2. the application of a kind of health food according to claim 1 in preparation raising immunity food.
3. a kind of health food according to claim 1, wherein health food is oral formulations.
4. a kind of health food according to claim 3, wherein oral formulations is tablet, pill, capsule or oral liquid.
5. a kind of health food according to claim 3, wherein health food is beverage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110256063.XA CN102342522B (en) | 2011-09-01 | 2011-09-01 | Health food |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110256063.XA CN102342522B (en) | 2011-09-01 | 2011-09-01 | Health food |
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| Publication Number | Publication Date |
|---|---|
| CN102342522A CN102342522A (en) | 2012-02-08 |
| CN102342522B true CN102342522B (en) | 2013-10-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201110256063.XA Expired - Fee Related CN102342522B (en) | 2011-09-01 | 2011-09-01 | Health food |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102919850B (en) * | 2012-05-21 | 2016-04-20 | 孟令刚 | A kind of composition for nutraceutical and medicine |
| CN103652940A (en) * | 2012-09-07 | 2014-03-26 | 江苏学府生物工程有限公司 | Production method of Cordyceps militaris polypeptide soft capsule |
| CN103053732A (en) * | 2012-12-18 | 2013-04-24 | 苏州天南星生物科技有限公司 | Health protection tea |
| CN104041830B (en) * | 2014-06-19 | 2015-08-26 | 青岛银色世纪健康产业集团有限公司 | A kind of fish skin collagen peptide compound product strengthening immunologic function and preparation method thereof |
| CN104524119A (en) * | 2014-12-10 | 2015-04-22 | 常州诺瑞格纳米科技有限公司 | Health product capable of preventing cold |
| CN104920935A (en) * | 2015-05-27 | 2015-09-23 | 淮南联合大学 | Asiatic cornelian cherry fruit total triterpene oral liquid and preparation method thereof |
| CN105901688A (en) * | 2015-12-14 | 2016-08-31 | 威海百合生物技术股份有限公司 | Calcium-retaining health food and preparation method thereof |
| CN106174217A (en) * | 2016-07-01 | 2016-12-07 | 广西博白县琼达农业科技有限公司 | A kind of rich vanadium black olive dumplings |
| CN109463603A (en) * | 2018-10-22 | 2019-03-15 | 春溟科技(北京)有限公司 | Cordyceps sinensis selenium oyster calcium solid granules and preparation method thereof |
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| CN1895664A (en) * | 2006-06-09 | 2007-01-17 | 杨德瑜 | Cordyceps sinensis and emu collagens peptide capsules and production thereof |
| CN101810336A (en) * | 2010-04-30 | 2010-08-25 | 广东仙乐制药有限公司 | Chewable soft capsules and method for preparing same |
| CN102133241A (en) * | 2011-03-15 | 2011-07-27 | 郭景龙 | Medicine composite with effect of improving immunity |
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2011
- 2011-09-01 CN CN201110256063.XA patent/CN102342522B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1362059A (en) * | 2001-01-05 | 2002-08-07 | 唐山王清任制药有限公司 | Nano Chinese medicine piece and its prepn |
| CN1895664A (en) * | 2006-06-09 | 2007-01-17 | 杨德瑜 | Cordyceps sinensis and emu collagens peptide capsules and production thereof |
| CN101810336A (en) * | 2010-04-30 | 2010-08-25 | 广东仙乐制药有限公司 | Chewable soft capsules and method for preparing same |
| CN102133241A (en) * | 2011-03-15 | 2011-07-27 | 郭景龙 | Medicine composite with effect of improving immunity |
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| CN102342522A (en) | 2012-02-08 |
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