CN102319423B - Health care product for treating habitual constipation caused by internal heat due to yin deficiency - Google Patents
Health care product for treating habitual constipation caused by internal heat due to yin deficiency Download PDFInfo
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- CN102319423B CN102319423B CN201110306595XA CN201110306595A CN102319423B CN 102319423 B CN102319423 B CN 102319423B CN 201110306595X A CN201110306595X A CN 201110306595XA CN 201110306595 A CN201110306595 A CN 201110306595A CN 102319423 B CN102319423 B CN 102319423B
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Abstract
The invention relates to a health care product for treating habitual constipation caused by internal heat due to yin deficiency. The health care product comprises the following raw materials in parts by weight: 20 to 60 parts of largehead atractylodes rhizome, 10 to 40 parts of stir-fried chicken gizzard membrane with vinegar, 20 to 40 parts of collagen, 10 to 20 parts of propolis, 1 to 2 parts of lycium barbarum polysaccharides, 1 to 2 parts of astragalus polysaccharides, 1-2 parts of eucommia bark polysaccharides, 1 to 2 parts of peppermint oil, 1 to 2 parts of vitamin E and an appropriate amount of refined honey. By adopting a supplement method rather than a simple reducing method, the cause of disease is eliminated, and gastrointestinal motility and bowel movement are restored.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of habitually health promoting product and preparation method thereof that is used for the treatment of yin asthenia generating intrinsic heat.
Background technology
After the habitual constipation outbreak (functional constipation), defecation is less than 3 times weekly, or defecation often feels difficulty, can be detained because of stool, and the toxin hyperabsorption, cholesterol absorption is too much, and complexion dusk is dim, too fat to move, causes hemorrhoid, anal fissure, has blood in stool, colorectal cancer.Habitual constipation is common in old people, pregnant and lying-in women, the patient of operative rehabilitation phase, causes the constitutional Intestinal motility owing to having a delicate constitution unusual, and the stool wriggling is carried and delayed.The method for the treatment of constipation is that to rush down be main mostly, after the medication relieving constipation, causes again the secondary constipation.Simultaneously, cathartic causes that easily the power and water solution matter of body is disorderly, and habitual constipation is without specific medicament.
The traditional Chinese medical science is thought: large intestine is the organ in charge of transportation, and here compound goes out.Post transmits waste matter, and with lung be the exterior and the interior, lung qi is respectful to fall, the defeated cloth of body fluid is normal, then large intestine internal organs gas is unobstructed, coming in and going out, there have to be normal.If work and rest mistake degree, take good care of oneself improper, intemperance of taking food or the pungent savoury of surfeit etc. cause damp and hot heresy to pent up large intestine, body fluid virtual loss or deficiency; Or affect mechanism of qi after operation or the severe injury, cause in venation block, qi depression to blood stasis, the turbid pathogen waste matter stagnation intestinal FU QI being obstructed, the difficult row of constipation, formation constipation.Therefore treatment blood stasis dispelling intestinal stasis relieving, the purging FU-organs of regulating the flow of vital energy, the methods of loosening bowel to relieve constipation of adopting more.
The treatment by Chinese herbs constipation has superiority.The Rhizoma Atractylodis Macrocephalae has QI invigorating, spleen invigorating dehumidifying and the antiabortive effect of hidroschesis.In treatise on Febrile Diseases, " Medical Treasures of the Golden Chamber ", Zhang Zhongjing is just just hard or let out continuous diarrhea with Rhizoma Atractylodis Macrocephalae treatment, still, the bitter dry impairment of YIN of the Rhizoma Atractylodis Macrocephalae, being only applicable to middle Jiao has wet card, as belonging to yin asthenia generating intrinsic heat or the dry thirsty person of body fluid deficiency, should not use, can not be used for yin asthenia generating intrinsic heat person's habitual constipation person.The habitual constipation Chinese medicine of exploitation treatment yin asthenia generating intrinsic heat, be the Traditional Chinese health product scope focus to be solved arranged for a long time.
Summary of the invention
The object of the invention provides a kind of habitually health promoting product and preparation method thereof that is used for the treatment of yin asthenia generating intrinsic heat.
The present invention relates to a kind of health promoting product that is used for the treatment of the habitual constipation of yin asthenia generating intrinsic heat, formed by the raw material of following weight portion:
Rhizoma Atractylodis Macrocephalae 20-60 part, vinegar Endothelium Corneum Gigeriae Galli (parched) 10-40 part, collagen protein 20-40 part, propolis 10-20 part, lycium barbarum polysaccharide 1-2 part, astragalus polysaccharides 1-2 part, eucommia bark polycose 1-2 part, Oleum menthae 1-2 part, vitamin e1-2 part, refined honey are an amount of.
The present invention is used for the treatment of the preparation method of health promoting product of the habitual constipation of yin asthenia generating intrinsic heat:
In the A step, the Rhizoma Atractylodis Macrocephalae, vinegar Endothelium Corneum Gigeriae Galli (parched) are ground into fine powder, obtain fine powder A for subsequent use;
In the B step, lycium barbarum polysaccharide, astragalus polysaccharides, eucommia bark polycose are mixed even, sieve, and obtain fine powder B for subsequent use;
C step, get collagen protein, propolis, Oleum menthae, vitamin E and be dissolved in the soybean oil, according to the film dispersion method preparation, add the ultrasonic hydration of distilled water, the solution supersound process obtains mixed liquor C, and is for subsequent use;
In the D step, with fine powder A for subsequent use, fine powder B for subsequent use, mixed liquor C is behind the mix homogeneously; Add refined honey and/or distilled water, be mixed and made into honeyed pill.This is health product of the present invention.
The present invention relates to a kind of health promoting product that is used for the treatment of the habitual constipation of yin asthenia generating intrinsic heat, preferably the raw material by following weight portion forms:
20 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of vinegar Endothelium Corneum Gigeriae Galli (parched)s, 20 parts of collagen protein, 10 parts of propolis, 1 part of lycium barbarum polysaccharide, 1 part of astragalus polysaccharides, 1 part of eucommia bark polycose, 1 part of Oleum menthae, vitamin e1 part, refined honey are an amount of.
The present invention relates to a kind of health promoting product that is used for the treatment of the habitual constipation of yin asthenia generating intrinsic heat, preferably the raw material by following weight portion forms:
60 parts of the Rhizoma Atractylodis Macrocephalaes, 40 parts of vinegar Endothelium Corneum Gigeriae Galli (parched)s, 40 parts of collagen protein, 20 parts of propolis, 2 parts of lycium barbarum polysaccharide, 2 parts of astragalus polysaccharidess, 2 parts of eucommia bark polycoses, 2 parts of Oleum menthae, vitamin E2 part, refined honey are an amount of.
The present invention is according to the principle of differentiation of tcm, follow " treating both the principal and secondary aspects of a disease " principle, adopt that YIN nourishing and the production of body fluid promoting is moisturized, the method for clearing away heat and resolving stagnation of food, diarrhea relieving constipation, invigorating the spleen and benefiting QI, Hezhong Huazhi, reinforcing the kidney and supporting YANG, take the Rhizoma Atractylodis Macrocephalae as monarch drug, take propolis, vinegar Endothelium Corneum Gigeriae Galli (parched) as ministerial drug.The propolis bitterness is hot, returns spleen, stomach warp, can suppress the dry property of the Rhizoma Atractylodis Macrocephalae, and tonify deficiency for oral administration is weak, change turbid fat, only quench one's thirst.The vinegar Endothelium Corneum Gigeriae Galli (parched), removing food stagnancy stagnates, strengthening the spleen and stomach.Lycium barbarum polysaccharide, astragalus polysaccharides, eucommia bark polycose be adjuvant drug, Oleum menthae for making medicine, priming effect composition enters large intestine channel.All medicines are harmonious, and have the intestinal stasis relieving of purging heat, and loosening bowel to relieve constipation is not hindered the effect of healthy energy.
The invention belongs to pure Chinese medicine health-care product, safe, the secondary constipation can not appear.
The preparation method of lycium barbarum polysaccharide: Fructus Lycii adds distilled water, homogenate, 100 degrees centigrade heat treated 2-4 hour, 95% ethanol precipitation is got precipitation, vacuum drying is pulverized and is obtained the lycium barbarum polysaccharide coarse powder.
The preparation method of astragalus polysaccharides: the Radix Astragali adds distilled water, homogenate, 90 degrees centigrade microwave treatment 0.5-1 hour, 95% ethanol precipitation is got precipitation, vacuum drying is pulverized and is obtained the astragalus polysaccharides coarse powder.
The preparation method of eucommia bark polycose: the Cortex Eucommiae adds distilled water, homogenate, 90 degrees centigrade microwave treatment 0.5-1 hour, 95% ethanol precipitation is got precipitation, vacuum drying is pulverized and is obtained the eucommia bark polycose coarse powder.
The preparation method of lycium barbarum polysaccharide, astragalus polysaccharides, eucommia bark polycose includes, without being limited to above technology.
Specific embodiment
Embodiment 1
A kind of health promoting product that is used for the treatment of the habitual constipation of yin asthenia generating intrinsic heat is comprised of the raw material of following weight portion:
20 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of vinegar Endothelium Corneum Gigeriae Galli (parched)s, 20 parts of collagen protein, 10 parts of propolis, 1 part of lycium barbarum polysaccharide, 1 part of astragalus polysaccharides, 1 part of eucommia bark polycose, 1 part of Oleum menthae, vitamin e1 part, refined honey are an amount of.
In the A step, the Rhizoma Atractylodis Macrocephalae, vinegar Endothelium Corneum Gigeriae Galli (parched) are ground into fine powder, obtain fine powder A for subsequent use;
In the B step, lycium barbarum polysaccharide, astragalus polysaccharides, eucommia bark polycose are mixed even, sieve, and obtain fine powder B for subsequent use;
C step, get collagen protein, propolis, Oleum menthae, vitamin E and be dissolved in the soybean oil, according to the film dispersion method preparation, add the ultrasonic hydration of distilled water, the solution supersound process obtains mixed liquor C, and is for subsequent use;
In the D step, with fine powder A for subsequent use, fine powder B for subsequent use, mixed liquor C is behind the mix homogeneously; Add refined honey and/or distilled water, be mixed and made into honeyed pill.
Embodiment 2
A kind of health promoting product that is used for the treatment of the habitual constipation of yin asthenia generating intrinsic heat is comprised of the raw material of following weight portion:
60 parts of the Rhizoma Atractylodis Macrocephalaes, 40 parts of vinegar Endothelium Corneum Gigeriae Galli (parched)s, 40 parts of collagen protein, 20 parts of propolis, 2 parts of lycium barbarum polysaccharide, 2 parts of astragalus polysaccharidess, 2 parts of eucommia bark polycoses, 2 parts of Oleum menthae, vitamin E2 part, refined honey are an amount of.
In the A step, the Rhizoma Atractylodis Macrocephalae, vinegar Endothelium Corneum Gigeriae Galli (parched) are ground into fine powder, obtain fine powder A for subsequent use;
In the B step, lycium barbarum polysaccharide, astragalus polysaccharides, eucommia bark polycose are mixed even, sieve, and obtain fine powder B for subsequent use;
C step, get collagen protein, propolis, Oleum menthae, vitamin E and be dissolved in the soybean oil, according to the film dispersion method preparation, add the ultrasonic hydration of distilled water, the solution supersound process obtains mixed liquor C, and is for subsequent use;
In the D step, with fine powder A for subsequent use, fine powder B for subsequent use, mixed liquor C is behind the mix homogeneously; Add refined honey and/or distilled water, be mixed and made into honeyed pill.
Embodiment 3
Health product of the present invention promote the impact of function on the Constipation Model intestine in rats
With 50 wistar rats, 200 ± 20g, male and female half and half, random packet is divided into Normal group, Constipation Model group, embodiment 2 high dose group, embodiment 2 low dose group, 10 every group.
Carry out modeling according to the herbal pharmacology laboratory manual: with compound diphenoxylate 60mg/kg gavage, continuous 10 days, during normal diet, form Constipation Model.
Embodiment 2 high dose group 50mg (crude drug)/kg, embodiment 2 low dose group 20mg (crude drug)/kg gavages, continuous 10 days, during normal diet, 2 times/d.
Not husky Billy (5mg/kg) gavage, continuous 10 days, during normal diet, 2 times/d.
According to literature processing experiment, observe defecation time, total number of defecation and 4h excrement are heavy in the record administration 4h.The results are shown in Table.
Be subjected to reagent on the impact (x ± S, n=10) of rat model intestine movement function
| Group | Dosage | Defecation time (min) | 4h excrement heavy (g) | The total grain of defecation number in the 4h |
| Normal group | ----- | 39.9±3.2 | 0.53±0.12 | 10.2±1.7 |
| Model group | ----- | 88.5±5.4 | 0.35±0.07 | 5.7±1.1* |
| Embodiment 2 low dose group | 20mg (crude drug)/kg | 54.7±4.9* | 0.43±0.14* | 7.6±1.3* |
| Embodiment 2 high dose group | 50 (crude drug) mg/kg | 41.9±2.5* | 0.48±0.17** | 8.5±0.9** |
| Not husky Billy | 5mg/kg | 70.83±5.2* | 0.40±0.09* | 6.2±1.1* |
Compare with model control group: * p＜0.05, * * p＜0.01.
Embodiment 2 can promote the defecation of constipation rat, and the high dose group effect is remarkable.
Embodiment 4 health product of the present invention are to the effect of the habitual constipation of yin asthenia generating intrinsic heat
The yin asthenia generating intrinsic heat person, constipation with dry stool such as sheep dung shape, emaciated physique, the ring of dizzy order, soreness of the waist and knees or see flushed cheeks night sweat, the resembling of the yin asthenia generating intrinsic heat such as the few Tianjin of xerostomia, dysphoria with feverish sensation in the chest palms and soles, halitosis, dryness in the nasal cavity.
" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that criterion of therapeutical effect is issued with reference to national traditional chinese medical science administration,
Cure: just matter turned profit, and was unobstructed during solution with interior defecation 1 time in 2 days, and 6 weeks did not recur
Take a turn for the better: just matter turned profit with interior defecation in 3 days, and it is smooth that defecation is owed;
Do not heal: symptom is without improvement.
Therapeutic outcome
Treatment group 50 examples, the men and women half and half, random distribution, 50 (crude drugs) mg/ time, 1 day twice, continue 30 days, cure 20 examples, account for 40%; 23 examples that take a turn for the better account for 46%; 7 examples more account for 14%.
Matched group 50 examples, the men and women half and half, random distribution, not husky Billy, 5mg/ time, 1 day twice, continue 30 days, cure 15 examples, account for 30%; 11 examples that take a turn for the better account for 22%; 24 examples more account for 48%.
Two groups of differences have very significant (P＜0.01).
Claims (1)
1. health promoting product that is used for the treatment of the habitual constipation of yin asthenia generating intrinsic heat, it is characterized in that: the raw material by following weight portion forms:
Rhizoma Atractylodis Macrocephalae 20-60 part, vinegar Endothelium Corneum Gigeriae Galli (parched) 10-40 part, collagen protein 20-40 part, propolis 10-20 part, lycium barbarum polysaccharide 1-2 part, astragalus polysaccharides 1-2 part, eucommia bark polycose 1-2 part, Oleum menthae 1-2 part, vitamin e1-2 part, refined honey are an amount of;
The preparation method of lycium barbarum polysaccharide: Fructus Lycii adds distilled water, homogenate, 100 degrees centigrade heat treated 2-4 hour, 95% ethanol precipitation is got precipitation, vacuum drying is pulverized and is obtained the lycium barbarum polysaccharide coarse powder;
The preparation method of astragalus polysaccharides: the Radix Astragali adds distilled water, homogenate, 90 degrees centigrade microwave treatment 0.5-1 hour, 95% ethanol precipitation is got precipitation, vacuum drying is pulverized and is obtained the astragalus polysaccharides coarse powder;
The preparation method of eucommia bark polycose: the Cortex Eucommiae adds distilled water, homogenate, 90 degrees centigrade microwave treatment 0.5-1 hour, 95% ethanol precipitation is got precipitation, vacuum drying is pulverized and is obtained the eucommia bark polycose coarse powder.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110306595XA CN102319423B (en) | 2011-10-11 | 2011-10-11 | Health care product for treating habitual constipation caused by internal heat due to yin deficiency |
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| CN201110306595XA CN102319423B (en) | 2011-10-11 | 2011-10-11 | Health care product for treating habitual constipation caused by internal heat due to yin deficiency |
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| CN102319423B true CN102319423B (en) | 2013-05-01 |
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