CN102293917B - Medicine for treating myocarditis - Google Patents
Medicine for treating myocarditis Download PDFInfo
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- CN102293917B CN102293917B CN 201110266960 CN201110266960A CN102293917B CN 102293917 B CN102293917 B CN 102293917B CN 201110266960 CN201110266960 CN 201110266960 CN 201110266960 A CN201110266960 A CN 201110266960A CN 102293917 B CN102293917 B CN 102293917B
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- parts
- medicine
- rhizoma
- treating myocarditis
- myocarditis
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- 239000003814 drug Substances 0.000 title claims abstract description 22
- 229940079593 drug Drugs 0.000 title claims abstract description 6
- 208000009525 Myocarditis Diseases 0.000 title abstract description 8
- 241001522129 Pinellia Species 0.000 claims abstract description 3
- 241000628997 Flos Species 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 241000245240 Lonicera Species 0.000 claims description 2
- 241000545442 Radix Species 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 7
- 230000008901 benefit Effects 0.000 abstract description 2
- 244000001632 Acorus gramineus Species 0.000 abstract 1
- 235000013073 Acorus gramineus Nutrition 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 244000288705 Chrysosplenium alternifolium Species 0.000 abstract 1
- 235000017405 Chrysosplenium alternifolium Nutrition 0.000 abstract 1
- 241000244987 Daiswa polyphylla Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 240000002948 Ophiopogon intermedius Species 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 241000411851 herbal medicine Species 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 description 4
- 230000006793 arrhythmia Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 3
- 206010019280 Heart failures Diseases 0.000 description 2
- 239000009636 Huang Qi Substances 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000004062 sedimentation Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010047470 viral myocarditis Diseases 0.000 description 2
- 102000004625 Aspartate Aminotransferases Human genes 0.000 description 1
- 108010003415 Aspartate Aminotransferases Proteins 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 102000004420 Creatine Kinase Human genes 0.000 description 1
- 108010042126 Creatine kinase Proteins 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 108010044467 Isoenzymes Proteins 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 241001570521 Lonicera periclymenum Species 0.000 description 1
- 208000000418 Premature Cardiac Complexes Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010042434 Sudden death Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
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- 238000002555 auscultation Methods 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 239000006189 buccal tablet Substances 0.000 description 1
- 229940046011 buccal tablet Drugs 0.000 description 1
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- 239000008101 lactose Substances 0.000 description 1
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- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Abstract
The invention relates to a medicine for treating myocarditis. The medicine for treating myocarditis is prepared from the following Chinese herbal medicines: honeysuckle flower, sophorae flavescentis, pinellia ternate, liquorice, paris polyphylla, ligusticum wallichii, acorus gramineus, dwarf lilyturf tuber, Chinese magnoliavine fruit, golden saxifrage and astragalus. The medicine for treating myocarditis is prepared from natural medicines, so the medicine for treating myocarditis has the advantages of quick response, good curative effect and no toxic or side effect.
Description
Technical field
The present invention relates to field of medicaments, specifically, relate to a kind of myocarditic medicament for the treatment of.
Background technology
Myocarditis refers to have in the cardiac muscle limitation or diffuse acute, subacute or chronic inflammatory lesion.The relative incidence rate of viral myocarditis constantly increases in recent years.State of an illness weight is different, shows widely differently, and how heavier the infant state of an illness is, and much lighter the adult is, and the lighter can be without obvious condition of illness, and severe one can concurrent severe arrhythmia, cardiac insufficiency even sudden death.The prodrome of acute stage or subacute stage myocarditis, patient can have heating, tired, hyperhidrosis, nervous, out of breath, precordial fullness pain etc.Check the arrhythmia such as visible premature beat, conduction block.Glutamic oxaloacetic transaminase, GOT, atrophy accompanied by elevation of CK, erythrocyte sedimentation rate speeds.Electrocardiogram, x-ray inspection help diagnosis.Treatment comprises rests, and improves myocardial nutrition, control cardiac insufficiency and corrects arrhythmia, prevents secondary infection etc.
Summary of the invention
The purpose of this invention is to provide a kind of myocarditic medicament for the treatment of.
In order to realize purpose of the present invention, the invention provides a kind of myocarditic medicament for the treatment of, it is to be made by weight by following bulk drugs: Flos Lonicerae 5-10 part, Radix Sophorae Flavescentis 10-20 part, Rhizoma Pinelliae 20-30 part, Radix Glycyrrhizae 10-20 part, Rhizoma Paridis 10-20 part, Rhizoma Chuanxiong 5-15 part, Rhizoma Acori Graminei 10-30 part, Radix Ophiopogonis 10-20 part, Fructus Schisandrae Chinensis 5-10 part, Herba euphorbiae lunulatae 10-20 and Radix Astragali 5-10 part.
Preferably, it is to be made by weight by following bulk drugs: 8 parts of 8 parts of Flos Loniceraes, 15 parts of Radix Sophorae Flavescentiss, 25 parts of the Rhizoma Pinelliaes, 15 parts in Radix Glycyrrhizae, 15 parts of Rhizoma Paridis, 10 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Acori Graminei, 15 parts of Radix Ophiopogonis, 8 parts of Fructus Schisandrae Chinensis, Herba euphorbiae lunulatae 15 and the Radixs Astragali.
Preferably, described medicament is tablet, dispersible tablet, buccal tablet, powder or granule.
Use natural drug in the myocarditic medicine for the treatment of of the present invention, so its advantage that has instant effect, good effect, has no side effect.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 powder of the present invention
Extracting honeysuckle 80 gram, Radix Sophorae Flavescentis 150 grams, the Rhizoma Pinelliae 250 grams, Radix Glycyrrhizae 150 grams, Rhizoma Paridis 150 grams, Rhizoma Chuanxiong 100 grams, Rhizoma Acori Graminei 200 grams, Radix Ophiopogonis 150 gram, Fructus Schisandrae Chinensis 80 grams, Herba euphorbiae lunulatae 15 and the Radix Astragali 80 grams, pulverize, cross 100 mesh sieves, then add lactose 100 grams and mannitol 200 grams, mixing is packed in 100 bags and be get final product.
Experimental example
Select 120 routine patients all to meet the 7th edition internal medicine diagnosis of viral myocarditis standard, male 64 examples wherein, women 56 examples, age 12-54 year; Upper respiratory tract infection history 75 examples are arranged.Heating shower 81 examples are arranged, weak 95 examples, uncomfortable in chest, cardiopalmus 82 examples, precordialgia, pale complexion 62 examples, nausea and vomiting 39 examples among the 120 routine patients.The routine blood test numeration of leukocyte is: 4.1-15.3 x 10
9/ L, wherein leucocytosis＞10.0 x 10
9/ L 32 examples, acute stage erythrocyte sedimentation rate 48 examples that raise, serum creatine kinase isoenzyme 59 examples that raise.It is low flat or be inverted that patient with slight symptoms's electrocardiogram often shows as the T ripple, and limb lead low-voltage, severe one can occur that the ST section is forced down even myocardial infarction sample ST section is raised or abnormality Q wave, various arrhythmia can occur.
Treat with the medicine that makes among the embodiment 1, wherein one day 3 times, each one bag, treating January is a course for the treatment of.In therapeutic process, carry out cardiac auscultation, electrocardiographic oscillogram and trace electrocardiogram, record myocarditis situation.
Criterion of therapeutical effect
Produce effects: symptom and sign disappears substantially, and lab testing is normal, and it is normal that electrocardiogram recovers, and effectively: clinical symptoms partly disappears, and sign and lab testing are improved, and electrocardiogram takes a turn for the better; Invalid: clinical symptoms, sign and every coherence check are without improvement.
Through the observation of a course for the treatment of is arranged, finding has 120 patient treatment effects to be produce effects, and does not observe obvious untoward reaction during whole treatment.
Claims (2)
1. treat myocarditic medicament for one kind, it is characterized in that it is to be made by weight by following bulk drugs: 8 parts of 8 parts of Flos Loniceraes, 15 parts of Radix Sophorae Flavescentiss, 25 parts of the Rhizoma Pinelliaes, 15 parts in Radix Glycyrrhizae, 15 parts of Rhizoma Paridis, 10 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Acori Graminei, 15 parts of Radix Ophiopogonis, 8 parts of Fructus Schisandrae Chinensis, Herba euphorbiae lunulatae 15 and the Radixs Astragali.
2. the myocarditic medicament for the treatment of according to claim 1 is characterized in that, described medicament is tablet, powder or granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110266960 CN102293917B (en) | 2011-09-09 | 2011-09-09 | Medicine for treating myocarditis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110266960 CN102293917B (en) | 2011-09-09 | 2011-09-09 | Medicine for treating myocarditis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102293917A CN102293917A (en) | 2011-12-28 |
| CN102293917B true CN102293917B (en) | 2013-01-09 |
Family
ID=45354750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110266960 Expired - Fee Related CN102293917B (en) | 2011-09-09 | 2011-09-09 | Medicine for treating myocarditis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102293917B (en) |
-
2011
- 2011-09-09 CN CN 201110266960 patent/CN102293917B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN102293917A (en) | 2011-12-28 |
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Owner name: TIANJIANG PHARMACEUTICAL INDUSTRY CO., LTD., JIANG Free format text: FORMER OWNER: LIU JIE Effective date: 20130701 |
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Free format text: CORRECT: ADDRESS; FROM: 272111 JINING, SHANDONG PROVINCE TO: 214400 WUXI, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20130701 Address after: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee after: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin Address before: Department of Cardiology, first people's Hospital, 6 health Road, Shandong, Jining 272111, China Patentee before: Liu Jie |
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| TR01 | Transfer of patent right |
Effective date of registration: 20170419 Address after: 062350 Suning County, Cangzhou Province, the town of the town of the town of Wu Zhuang, No. Patentee after: Zhang Xueju Address before: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee before: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin |
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| TR01 | Transfer of patent right | ||
| CP02 | Change in the address of a patent holder |
Address after: Daze town Pingdu City 30% road 266000 Shandong city of Qingdao Province Patentee after: Zhang Xueju Address before: 062350 Suning County, Cangzhou Province, the town of the town of the town of Wu Zhuang, No. Patentee before: Zhang Xueju |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130109 Termination date: 20170909 |
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| CF01 | Termination of patent right due to non-payment of annual fee |