CN102284013A - Chinese herbal medicine preparation for treating hyperplasia of mammary glands - Google Patents
Chinese herbal medicine preparation for treating hyperplasia of mammary glands Download PDFInfo
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- CN102284013A CN102284013A CN2011102317741A CN201110231774A CN102284013A CN 102284013 A CN102284013 A CN 102284013A CN 2011102317741 A CN2011102317741 A CN 2011102317741A CN 201110231774 A CN201110231774 A CN 201110231774A CN 102284013 A CN102284013 A CN 102284013A
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Abstract
The invention discloses a Chinese herbal medicine preparation for treating hyperplasia of mammary glands. In order to overcome the defects in the background art, the invention provides a Chinese herbal medicine preparation for treating hyperplasia of mammary glands, which has the advantages of low price, obvious curative effect, short treatment period and no relapse and is convenient to use. The Chinese herbal medicine preparation for treating hyperplasia of mammary glands is prepared from the following Chinese herbal medicines: trichosanthes kirilowii Maxim, Gueldenstaedtia verna, antler, rhizoma pleionis, polygala japonica, geranium wilfordii, rhizoma bolbostemmae, Vincetoxicum amplexicaule, madder, pangolin and the like. The preparation method of the Chinese herbal medicine preparation for treating hyperplasia of mammary glands comprises the following steps: removing non-medicinal parts, washing, cleaning, drying, weighing according to the proportion, merging, pulverizing, passing through an 80 mesh screen, sterilizing, drying and packaging. The Chinese herbal medicine preparation for treating hyperplasia of mammary glands is taken with warm water three times a day, 10g a time. The treatment course is 15 days. The clinical data statistical analysis on 300 patients with hyperplasia of mammary glands indicates that the shortest time for treating hyperplasia of mammary glands is 1 week, the longest time is 3 weeks, and the effective rate is 100%.
Description
One, technical field:
The present invention relates to a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy, specifically, relating to a kind of is the oral powder of the treatment cyclomastopathy made of formula material with the Chinese herbal medicine.
Two, background technology:
Cyclomastopathy claims mammary dysplasia again, is a mammary gland parenchyma and a matter unusual in quantity and form of the breast structure due to hypertrophy and the subinvolution to some extent.Neither inflammation, also non-tumor.The danger that breast carcinoma takes place this patient is higher 1.4～1.5 times than healthy women, therefore is subjected to paying attention to widely.The pressure that modern female causes body and mind owing to work, family and social factor thereof, the sickness rate of cyclomastopathy have the trend that increases year by year.Have the patient of report cyclomastopathy account for the health check-up women 70% one 90% ", sexually revise though cyclomastopathy belongs to hyperplasia of prostate, the normal women of its danger that cancerates increases by 2～4 times.
Cyclomastopathy belongs to the traditional Chinese medical science " nodules of the breast " category, and " Waike Zhengzong, Orthodox Manual of External Diseases " said: " nodules of the breast is a nodule in the breast, shape such as ball ovum, or weigh down the recast pain, or not bitterly, color of the leather is constant, and it is examined with the susceptible to anger growth and decline, is that worry impairing spleen is arranged, angry impairing the liver, pent-up forms "." surgery case compilation " " nodule in the breast, though the cloud hepatopathy, the fundamental cause of water disease being in the kidney ".Described the clinical characters of " nodules of the breast ", emphasized that the generation of nodules of the breast is relevant with depression of liver-QI, illustrated kidney and dash the material impact of appointing in the cyclomastopathy morbidity.Herba Sidae Rhombifoliae soup commonly used clinically, XIAOYAO POWDER, bupleurum powder for relieving liver-qi, the combination of minor bupleurum decoction with power etc., flexibility is cut out, or QI and blood takes into account, or simultaneously using both cold and hot drugs, or reinforcement and elimination in combination, or harmonizing the liver and spleen, or conciliates the gallbladder stomach, conciliates about inside and outside, the traffic, dredges the purpose of boiling QI and blood thereby reach.
The medicine of treatment cyclomastopathy is more at present, as: the vitamin medicaments treatment (vitamin B of doctor trained in Western medicine
1, B
6, E etc.), adopt antiestrogenic endocrine therapy (tamoxifen, danazol, Ergolactin etc.), Chinese patent medicine is as XIAOYAO POWDER, XIAOJIN WAN, RUPIXIAO, RUKUAIXIAO etc.But Western medicine hormone antagonist class medicine easily causes the discomfort of endocrine regulation and human body, and the Chinese patent medicine that now appears on the market also can only play the effect of alleviation and can not obtain the radical cure.A kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy is exactly a basis disadvantages of background technology now, reaches cheap, and is evident in efficacy, and treatment cycle is short, and the remarkable result that does not recur after controlling is worth clinical expansion to use.
Three, summary of the invention:
The objective of the invention is in order to overcome disadvantages of background technology, and provide a kind of cheap, easy to use, evident in efficacy, treatment cycle short, a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy of not recurring after controlling.This prescription does not still have report so far, and the medical material of use is a Chinese herbal medicine.
For achieving the above object, the technical solution used in the present invention is: a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy is characterized in that it contains the Chinese herbal medicine of compositions such as Fructus Trichosanthis, Gueldenstaedtia verna, Cornu Cervi, Pseudobulbus Cremastrae Seu Pleiones, Lepidogrammitis drymoglossoides (Bak.) Ching, Herba Erodii, Rhizoma Bolbostematis, Radix Cynanchi Amplexicaulis, Radix Rubiae, Squama Manis.
The technical solution used in the present invention is: a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy is that it contains the Chinese herbal medicine formula of following weight portion: Fructus Trichosanthis 180-250 part, Gueldenstaedtia verna 180-250 part, Cornu Cervi 35-50 part, Pseudobulbus Cremastrae Seu Pleiones 35-50 part, Lepidogrammitis drymoglossoides (Bak.) Ching 80-120 part, Herba Erodii 80-120 part, Rhizoma Bolbostematis 80-120 part, Radix Cynanchi Amplexicaulis 80-120 part, Radix Rubiae 120-180 part, Squama Manis 120-180 part.
The optimal technical scheme that drug dose of the present invention adopts is: a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy is characterized in that it contains the Chinese herbal medicine of following weight portion: 200 parts of Fructus Trichosanthis, 200 parts of Gueldenstaedtia vernas, 40 parts on Cornu Cervi, 40 parts of Pseudobulbus Cremastrae Seu Pleioness, 100 parts of Lepidogrammitis drymoglossoides (Bak.) Chings, 100 parts of Herba Erodiis, 100 parts of Rhizoma Bolbostematiss, 100 parts of Radix Cynanchi Amplexicauliss, 150 parts in Radix Rubiae, 150 parts of Squama Maniss.
The present invention's " a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy ", the Chinese herbal medicine plant and animal material that is adopted is:
Fructus Trichosanthis is that calabash material snake gourd plant Fructus Trichosanthis Trichosanthes kirilowii Maxim is used as medicine with mature fruit.(" Pharmacopoea Chinensis " 2010 editions one one)
Gueldenstaedtia verna is that leguminous plant Gueldenstaedtia verna Gueldenstaedtia multiflora Bge is with all herbal medicine.(the new medical college in Jiangsu " Chinese medicine voluminous dictionary ")
Cornu Cervi is that animal in deer family deer Cervus nippon Temminck is used as medicine with ossified angle.(" Pharmacopoea Chinensis " 2010 editions one one)
Pseudobulbus Cremastrae Seu Pleiones is that orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino. is used as medicine with pseudobulb.(" Pharmacopoea Chinensis " 2010 editions one one)
Lepidogrammitis drymoglossoides (Bak.) Ching is that Polypodiaceae plant Drymoglossum Herba Drymoglossi Lepidogrammitis drymoglossoides (Bak) ching is with all herbal medicine.Dictionary (the new medical college in Jiangsu " Chinese medicine voluminous dictionary ")
Geranium wilfordii is that the plant Herba Erodii Ceranium wilfordii Maxim of Mang cattle Seedling section is with all herbal medicine.(" Pharmacopoea Chinensis " 2010 editions one one)
Rhizoma Bolbostematis is that cucurbitaceous plant Rhizoma Bolbostematis Bolbostemma Paniculatum (Maxim) Franguet. is used as medicine with dry tuber.(" Pharmacopoea Chinensis " 2010 editions one one)
Radix Cynanchi Amplexicaulis is that asclepiadaceae plant Radix Cynanchi Amplexicaulis Cynanchum amplexicaule Hemsl is used as medicine with rhizome.(the new medical college in Jiangsu " Chinese medicine voluminous dictionary ")
Radix Rubiae be Maguireothamnus speciosus Radix Rubiae Rubia cordifolia L. with dry root and rhizome be used as medicine.(" Pharmacopoea Chinensis " 2010 editions one one)
Squama Manis is the dace first of Manidae animal Manitis Manis pentadactyla L., is used as medicine with the dace first.(the new medical college in Jiangsu " Chinese medicine voluminous dictionary ")
The process technology scheme that the present invention adopts is to adopt conventional preparation method to be prepared from: with Fructus Trichosanthis, Gueldenstaedtia verna, Cornu Cervi, Pseudobulbus Cremastrae Seu Pleiones, Lepidogrammitis drymoglossoides (Bak.) Ching, Herba Erodii, Rhizoma Bolbostematis, Radix Cynanchi Amplexicaulis, Radix Rubiae, Squama Manis through cleaning dry back by the proportioning weighing of writing out a prescription, merge and pulverized 80 mesh sieves, sterilization, packing gets final product.
Using method: each 10 grams, every day three times, warm water delivery service.15 days is a course of treatment.
Acute toxicity test: the oral said preparation 10g/kg of mice, be equivalent to oral 50 times of human body, untoward reaction and death do not appear.
Clinical trial: for showing " a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy ", for the therapeutic effect of cyclomastopathy, the inventor has done statistical analysis to 300 routine cyclomastopathy patients (wherein: the oldest 52 years old, minimum 31 years old) clinical data.The result shows: adopt " a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy " treatment cyclomastopathy, the shortest time was 1 week, was 3 weeks the most for a long time, and effective percentage is 100%.
Model case:
Case 1: Cao, the woman, 41 years old, live two groups in Chinese olive village, Zhenan County, go to a doctor in August, 2006.
The main suit: the bilateral distending pain of the breast played streak lump 6 years, increase the weight of through preceding outbreak, through after alleviate gradually, the few color of menstrual blood volume is dark, poor sleep, temper agitation.
Diagnosis: show bilateral breast hypertrophy through the report of infrared chart diagnosis of scans.
Treatment: use alleviate one week of medicine of the present invention, the diffusing piece of two week knots disappears, and the recovery from illness of three weeks was checked to hospital after March, and cyclomastopathy disappears.Follow up a case by regular visits to, do not see recurrence so far.
Case 2: Liu 40 years old, live cloud desk temple, Zhenan County town December in 2008 and examined in 26th.
The main suit: mammary swelling is accompanied a burst of twinge, and nociceptive reflex is to sternocostal part and shoulder back.Companion's susceptible to lose temper due to restlessness, belch uncomfortable in chest, insomnia and dreamful sleep.
Diagnosis: show (1) cyclomastopathy through the report of infrared chart diagnosis of scans; (2) the secondary breast in left side.
Treatment: hospitalize: antiinflammatory five days, sick position one week of acupuncture of breast district.Oral ease pill, two weeks of XIAOJIN WAN, the state of an illness alleviates to some extent, and being difficulet and sulky because of house hold affairs after January makes disease relapse, one anti-as before, recommend through the people and to use three days pain reliefs of medicine of the present invention, one week back pain disappear.Logotype recovery from illness two courses of treatment disappears through hospital's check cyclomastopathy and secondary breast, follows up a case by regular visits to after 2 years and does not see recurrence.
Case 3: river, woman, 45 years old, live two vegetable gardens, Zhenan County, JIUYUE was examined on the 12nd in 2007.
The main suit: suffered from cystic hyperplasia of breast 1 year, Xijing examination in hospital data is arranged, show the about 3 * 2cm size of the right breast of PE outer below hardness matter Hard Roll piece, the border is clear, and mobility can.
Diagnosis: right newborn fibroadenoma.
Treatment: extract through hospital surgical, one week of antiinflammatory leaves hospital, right breast is gone up the swelling twinge outward after March, checks to hospital to be beading nodules, is diagnosed as cyclomastopathy, take medicine of the present invention upon somebody's introduction, the back pain disappearance of one week, lump dissipates mostly, serve on recovery from illness two courses of treatment, disappear through the check cyclomastopathy, follow up a case by regular visits to not recurrence after 2 years.
Four, the specific embodiment:
Prescription is formed and proportioning: 200 parts of Fructus Trichosanthis, 200 parts of Gueldenstaedtia vernas, 40 parts on Cornu Cervi, 40 parts of Pseudobulbus Cremastrae Seu Pleioness, 100 parts of Lepidogrammitis drymoglossoides (Bak.) Chings, 100 parts of Herba Erodiis, 100 parts of Rhizoma Bolbostematiss, 100 parts of Radix Cynanchi Amplexicauliss, 150 parts in Radix Rubiae, 150 parts of Squama Maniss.
Preparation method: raw medicinal materials such as Fructus Trichosanthis, Gueldenstaedtia verna, Cornu Cervi, Pseudobulbus Cremastrae Seu Pleiones, Lepidogrammitis drymoglossoides (Bak.) Ching, Herba Erodii, Rhizoma Bolbostematis, Radix Cynanchi Amplexicaulis, Radix Rubiae, Squama Manis are cleaned respectively, wash and cut, dry take by weighing respectively by prescription proportioning consumption, raw medicinal material is merged pulverized 80 mesh sieves, sterilization, packing promptly.
Prescription:
Microbial check: the every 1g of bacterial population must not be above 10000; The every 1g of mycete and yeast count must not be above 100; The every 1g of escherichia coli must not detect; The every 1g of coliform should be less than 100.
Moisture: must not surpass 9.0%.
Granularity: reach more than 95% by No. 5 sieves.
Store: airtight storage.
Claims (4)
1. Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy is characterized in that it contains the Chinese herbal medicine of compositions such as Fructus Trichosanthis, Gueldenstaedtia verna, Cornu Cervi, Pseudobulbus Cremastrae Seu Pleiones, Lepidogrammitis drymoglossoides (Bak.) Ching, Herba Erodii, Rhizoma Bolbostematis, Radix Cynanchi Amplexicaulis, Radix Rubiae, Squama Manis.
2. a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy according to claim 1 is that it contains the Chinese herbal medicine formula of following weight portion: Fructus Trichosanthis 180-250 part, Gueldenstaedtia verna 180-250 part, Cornu Cervi 35-50 part, Pseudobulbus Cremastrae Seu Pleiones 35-50 part, Lepidogrammitis drymoglossoides (Bak.) Ching 80-120 part, Herba Erodii 80-120 part, Rhizoma Bolbostematis 80-120 part, Radix Cynanchi Amplexicaulis 80-120 part, Radix Rubiae 120-180 part, Squama Manis 120-180 part.
3. a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy according to claim 1 is characterized in that it contains the Chinese herbal medicine of following preferred weight part: 200 parts of Fructus Trichosanthis, 200 parts of Gueldenstaedtia vernas, 40 parts on Cornu Cervi, 40 parts of Pseudobulbus Cremastrae Seu Pleioness, 100 parts of Lepidogrammitis drymoglossoides (Bak.) Chings, 100 parts of Herba Erodiis, 100 parts of Rhizoma Bolbostematiss, 100 parts of Radix Cynanchi Amplexicauliss, 150 parts in Radix Rubiae, 150 parts of Squama Maniss.
4. " a kind of Chinese herbal and crude drugs preparations for the treatment of cyclomastopathy " according to claim 1, the Chinese herbal medicine plant and animal material that is adopted is:
Fructus Trichosanthis is that calabash material snake gourd plant Fructus Trichosanthis Trichosanthes kirilowii Maxim is used as medicine with mature fruit.(" Pharmacopoea Chinensis " 2010 editions one one)
Gueldenstaedtia verna is that leguminous plant Gueldenstaedtia verna Gueldenstaedtia multifiora Bge is with all herbal medicine.(the new medical college in Jiangsu " Chinese medicine voluminous dictionary ")
Cornu Cervi is that animal in deer family deer Cervus nippon Temminck is used as medicine with ossified angle.(" Pharmacopoea Chinensis " 2010 editions one one)
Pseudobulbus Cremastrae Seu Pleiones is that orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino. is used as medicine with pseudobulb.(" Pharmacopoea Chinensis " 2010 editions one one)
Lepidogrammitis drymoglossoides (Bak.) Ching is that Polypodiaceae plant Drymoglossum Herba Drymoglossi Lepidogrammitis drymoglossoides (Bak) ching is with all herbal medicine.Dictionary (the new medical college in Jiangsu " Chinese medicine voluminous dictionary ")
Geranium wilfordii is that the plant Herba Erodii Ceranium wilfordii Maxim of Mang cattle Seedling section is with all herbal medicine.(" Pharmacopoea Chinensis " 2010 editions one one)
Rhizoma Bolbostematis is that cucurbitaceous plant Rhizoma Bolbostematis Bolbostemma Paniculatum (Maxim) Franguet. is used as medicine with dry tuber.(" Pharmacopoea Chinensis " 2010 editions one one)
Radix Cynanchi Amplexicaulis is that asclepiadaceae plant Radix Cynanchi Amplexicaulis Cynanchum amplexicaule Hemsl is used as medicine with rhizome.(the new medical college in Jiangsu " Chinese medicine voluminous dictionary ")
Radix Rubiae be Maguireothamnus speciosus Radix Rubiae Rubia cordifolia L. with dry root and rhizome be used as medicine.(" Pharmacopoea Chinensis " 2010 editions one one)
Squama Manis is the dace first of Manidae animal Manitis Manis pentadactyla L., is used as medicine with the dace first.(the new medical college in Jiangsu " Chinese medicine voluminous dictionary ").
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1410097A (en) * | 2002-11-21 | 2003-04-16 | 杜仰恩 | Chinese patent medicine for treating mastoncus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1410097A (en) * | 2002-11-21 | 2003-04-16 | 杜仰恩 | Chinese patent medicine for treating mastoncus |
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