CN102283940A - Chinese medicinal preparation for treating palpitation - Google Patents
Chinese medicinal preparation for treating palpitation Download PDFInfo
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- CN102283940A CN102283940A CN 201110218382 CN201110218382A CN102283940A CN 102283940 A CN102283940 A CN 102283940A CN 201110218382 CN201110218382 CN 201110218382 CN 201110218382 A CN201110218382 A CN 201110218382A CN 102283940 A CN102283940 A CN 102283940A
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Abstract
The invention discloses a Chinese medicinal preparation for treating palpitation. The Chinese medicinal preparation is prepared from the following Chinese herbal medicines in part by weight: 9 to 15 parts of golden thread, 9 to 15 parts of lightyellow sophora root, 12 to 18 parts of Chinese angelica, 15 to 18 parts of rehmannia root, 30 to 45 parts of spina date seed and 15 to 30 parts of platycladi seed. During preparation, the Chinese medicinal preparation can be prepared into various formulations which are used clinically, such as tablets, granules, capsules, pills and the like. In the Chinese medicinal preparation, the rehmannia root and the Chinese angelica are used for nourishing yin and blood to address root cause, the golden thread and the lightyellow sophora root are used for clearing heat and purging intense heat, and the spina date seed and the platycladi seed are used for soothing nerves and calming palpitation to address symptoms; and the Chinese herbal medicines are rigorous in compatibility, comprise monarch, minister, assistant and guide medicaments, are complementary to each other, have the effects of nourishing yin and blood, purging intense heat, soothing nerves, nourishing heart-yin, clearing away heart-fire, calming mind and the like, and are mainly used for treating palpitation, inquietude and rapid pulse due to deficiency of the heart-yin and excessive fire in heart. During treatment, the Chinese medicinal preparation is taken orally, one dose is taken every day, 6 to 7 days is one treatment course, and the palpitation can be cured for three or four treatment courses.
Description
Technical field
The invention provides a kind of Chinese medicine preparation for the treatment of cardiopalmus and preparation method thereof.
Background technology
Cardiopalmus (palpitation) refers to the conscious palpitation of patient, even a class symptom that can not be autonomous.During generation, the conscious rapid heart beat of patient and strong, and with the pareordia sense of discomfort.The category that belongs to motherland's medical science " palpitation with fear " and " severe palpitation ".This disease is found in the multiple lysis, and many and insomnia, forgetful, dizzy, tinnitus etc. are also deposited, and all a variety of causes cause that heartbeat frequency, the rhythm and pace of moving things take place all can cause cardiopalmus unusually.
Long and rich experience to primary disease research for motherland's medical science, belongs to " cardiopalmus ", " palpitation with a distress feeling " category, and how improper etc. because of body constitution, diet, seven emotions, medicine food, it is empty to cause that negative and positive of qi and blood loses, and lack of preservation of spirit or expectorant, drink, fire, the stasis of blood upset in the heart, malaise.The conscious irritability of patient, palpitation can not be autonomous, and often accompany uncomfortable in chest, breathe hard, symptom such as insomnia, forgetful, dizzy, tinnitus.This disease is found in the multiple lysis, and many and insomnia, forgetful, dizzy, tinnitus etc. are also deposited, and all a variety of causes cause that heartbeat frequency, the rhythm and pace of moving things take place all can cause cardiopalmus unusually.Clinical data shows that 83.0% sudden death patient is with this disease.Therefore, actively prevent and treat arrhythmia, significant to improving patient's life quality.Though modern medicine is easier to the primary disease clinical diagnosis, its treatment and evaluation prognosis are then difficult.Along with the progress of medical science, though at present interventional therapy may melt ectopic pacemaker fully, because of patient age is tending towards aging more, risk and treatment cost increase, thus Most patients can not be suitable for, so present antiarrhythmic drug is still the main line of treatment.But because the arrhythmia Western medicine itself has arrhythmogenic effect and can suppress the potential danger of heart normal physiological activity function, so its clinical tolerance, compliance are relatively poor; Electric in addition physiological action is single, so its range of application also is subjected to certain limitation.
At present, lack in the prior art cardiopalmus curative effect medicine preferably, the similar medicine of domestic medical market is less.
Summary of the invention
At above-mentioned prior art, the invention provides a kind of Chinese medicine preparation for the treatment of cardiopalmus, the present invention is based on the dialectical opinion of motherland's medical science and controls, and starts with from integrally-regulated, grows the heart-yin, clearing away heart-fire, tranquilizing mind; Make the patient ataraxy, the multiple body peace of rule.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine preparation for the treatment of cardiopalmus is made by following bulk drugs: 9～15 parts of Rhizoma Coptidis, 9～15 parts of Radix Sophorae Flavescentiss, 12～18 parts of Radix Angelicae Sinensis, 15～18 parts of Radix Rehmanniae, 30～45 parts of Semen Ziziphi Spinosaes, 15～30 parts of Semen Platycladi.
The Chinese medicine preparation of described treatment cardiopalmus can be made various dosage forms commonly used clinically, as tablet, granule, capsule, pill etc.
The preparation method of the Chinese medicine preparation of described treatment cardiopalmus is:
(1) get Rhizoma Coptidis, Radix Sophorae Flavescentis, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Ziziphi Spinosae, Semen Platycladi, decoct with water respectively, amount of water is 8～12 times of quality of medicinal material, extracts 1～3 time, each 1～2 hour, collects volatile oil;
(2) merge above-mentioned decocting liquid, filter, filtrate is concentrated into the extractum that relative density is 1.19～1.20 (60 ℃);
(3) adding 95% ethanol (volume mass mark) in extractum is 60% (volume mass mark) to containing the alcohol amount, leaves standstill 24 hours; Get supernatant, filter, reclaim ethanol, being concentrated into relative density is the thick paste of (60 ℃) more than 1.30;
(4) with equivalent extract at 60～80 ℃ of following drying under reduced pressure, pulverized 80 mesh sieves, drug powder, add conventional excipient substance, make tablet, granule, capsule or pill.Such as, preparation during granule, dry granulation behind (drug powder quality 5%) the dextrin mixing that adds 5%, granulate, granular preparation.Preparation is during capsule, granule incapsulated get final product.
In the prescription of the present invention, Rhizoma Coptidis, Radix Sophorae Flavescentis, Radix Angelicae Sinensis and Radix Rehmanniae are monarch-minister drug altogether, and Semen Ziziphi Spinosae and Semen Platycladi are adjuvant altogether, and the drug effect of each raw material is as follows:
Rhizoma Coptidis: its bitter in the mouth, cold in nature, warps such as GUIXIN, liver.Effect is a heat clearing and damp drying, eliminating fire and detoxication.Rhizoma Coptidis is kind clear away heart-fire through fire, be the medicine commonly used of " eliminating heart-fire "; " book on Chinese herbal medicine newly organized " said: " Rhizoma Coptidis goes into the heart and collaterals of the uterus, and pathogenic fire purging also can be gone into liver, asks to join one the medicine of tying-in greatly, all can go into it, and it is outstanding also full-time to go into the heart "; Point out in " Treatise on Febrile Disease with Notes " that Rhizoma Coptidis can " catharsis heart purgation deficiency-heat "; " pearl sac " said: " Rhizoma Coptidis its with having four: removing pathogen in the heart dirty fiery is also ... ", and claim that it can " remove sun have a surplus, the cool heart reduces phlegm and internal heat ".
Radix Sophorae Flavescentis: its bitter in the mouth, cold in nature, warps such as GUIXIN, liver.Effect is a heat clearing and damp drying, wind dispelling insecticide, diuresis." book on Chinese herbal medicine is through hundred kinds of records " title Radix Sophorae Flavescentis " specially control the fire of heart channel, close with the Rhizoma Coptidis function, be many but Rhizoma Coptidis seemingly removes the fire of heart, it is many that Radix Sophorae Flavescentis seemingly removes the fire of heart internal organs small intestinal "; Compendium of Material Medica then claims its " can the kidney invigorating, only kidney water is weak and phase hyperactivity of fire person is suitable with it ", and thinks its " can the kidney invigorating, cover and get its bitter dampness, cold heat extraction also ".Rhizoma Coptidis and Radix Sophorae Flavescentis two medicines match, and Rhizoma Coptidis is gone on, and are many to remove monarch fire; Radix Sophorae Flavescentis is gone down, and is advisable to remove mutually fire.Burning hot decline, heat go that then blood is peaceful, are ministerial drug altogether.The shared cloudy heart-yang that presses down that nourishes heart of two groups of medicines of the monarch and his subjects, clearing away heart-fire protects the heart-yin.
Radix Angelicae Sinensis: its sweet in the mouth, suffering, warm in nature, return warps such as liver, the heart.Effect is invigorated blood circulation for enriching blood, pain relieving, intestine moistening." book on Chinese herbal medicine is looked for the truth " said: " Radix Angelicae Sinensis is specially gone into the heart.Hot sweet gentle, all books carry to going into the heart being responsible for production of blood top grade "; " book on Chinese herbal medicine just " claims " so specially can enrich blood, its gas is light and hot for Radix Angelicae Sinensis, its sweet in the mouth and weigh, again can promoting the circulation of blood, invigorating middle warmer has, in the row benefit is arranged, the sincere gas medicine in the blood, the panacea in the blood also ", and " blood deficiency blood depletion, the card of the moon branch loss all should be used it " such as; " curing mainly secret formula " claim its " though warm in nature, and blood deficiency have hot person also available it, because of its can hemopoietic be YIN nourishing, YIN nourishing can be brought down a fever also "; " book on Chinese herbal medicine through hundred kinds of records " then claims its " specially in enriching blood, blood mend then that the moon is so incensed that and ".Radix Rehmanniae and Radix Angelicae Sinensis two medicines are monarch drug altogether, the cloudy blood of reinforcing the heart and the kidney nourishing water of holding concurrently is played the merit that tonifying YIN is held back sun.
Radix Rehmanniae: its sweet in the mouth, hardship, cold in nature, GUIXIN, liver, kidney channel.Effect is a clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting." Bencao Jingshu " claims that Radix Rehmanniae is " key medicine of the kidney invigorating man, product on the tonifying YIN blood "; " Japan hanako materia medica " claims that it can " control palpitation with fear labor bad ", and " can hemopoietic can YIN nourishing, can YIN nourishing can bring down a fever also "; " herbal classic is met former " claims " cloudy little excess of YANG, the phase heated is strong, takes advantage of cloudy position, day by day decocts; the disease of hyperactivity of fire caused by deficiency of YIN, suitable Radix Rehmanniae moves back sun with YIN nourishing ", and " interior special removing heat from blood YIN nourishing is moistened skin outward; Rong Ze, and patient is empty and have hot person to add to use it ... the merit of moisturizing is arranged, and have the greasy trouble of taste also.
Semen Ziziphi Spinosae: its sweet in the mouth, property is flat, GUIXIN, Liver Channel.Effect is a tranquilizing by nourishing the heart, arresting sweating.Semen Ziziphi Spinosae can nourish heart the moon, the liver benefiting blood and mind tranquilizing and the heart calming, Shennong's Herbal claims its " main trusted subordinate's cold and heat ... obey settling five organs are for a long time made light of one's life by commiting suicide and prolonged life "; " Mingyi Bielu " claims it to lead " vexatious insomnia ", " sweating due to debility ", " the liver benefiting gas ", " invigorating middle warmer ", " helping cloudy gas " again; " book on Chinese herbal medicine converge with speech " claims that it can " astringing QI be calmed the nerves "; " the careless cut of dwelling " then claim its " though property convergence and abnormal smells from the patient is flat, when assistant with his medicine, its merit is seen by the side ... assistant is returned ground, can hold back blood and nutrition is Kidney-Yin ".
Semen Platycladi: its sweet in the mouth, property is flat, warps such as GUIXIN, kidney.Effect is a tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Compendium of Material Medica claims that Semen Platycladi can " gas that nourishes heart, the profit kidney is dry, the peace soul decide soul, Fructus Alpiniae Oxyphyllae is allayed excitement ", and " Semen Platycladi is flat and cold not dry, sweet in the mouth and mend Xin Erneng profit, its gas delicate fragrance, heart kidney thoroughly "; Shennong's Herbal then claims its " main palpitation with fear ... settling five organs ".Semen Ziziphi Spinosae and Semen Platycladi two medicines match and assist the monarch and his subjects, nourishing YIN and benefiting blood, and mind tranquilizing and the heart calming is adjuvant altogether.
Radix Rehmanniae in the prescription, Radix Angelicae Sinensis nourishing YIN and benefiting blood are to effect a permanent cure, and Rhizoma Coptidis, Radix Sophorae Flavescentis clearing away heat-fire, Semen Ziziphi Spinosae, Semen Platycladi are calmed the nerves and throbbed with fear surely to take stopgap measures; All medicine compatibilities are rigorous, and monarch is had, and complement each other the merit of playing nourishing YIN and benefiting blood altogether, relieving inflammation or internal heat and calming the nerves; Have effects such as the heart-yin of taste, clearing away heart-fire, tranquilizing mind, cure mainly deficiency of heart-yin, the moving uneasiness of the prosperous cardiopalmus of heart-fire, thready and rapid pulse for main pathogenesis.During treatment, oral, every day potion, 6-7 days is a course of treatment, general three or can cure four courses of treatment.
The raw materials used medicine of Chinese medicine preparation of the present invention is all cheap and easy to get, and cost of manufacture is low, good effect.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment.
The Chinese medicine preparation (granule) of embodiment 1 preparation treatment cardiopalmus
Prescription is: Rhizoma Coptidis 12 grams, Radix Sophorae Flavescentis 12 grams, Radix Angelicae Sinensis 15 grams, Radix Rehmanniae 16 grams, Semen Ziziphi Spinosae 38 grams, Semen Platycladi 22 grams (potion).
Preparation method is:
(1) get Rhizoma Coptidis, Radix Sophorae Flavescentis, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Ziziphi Spinosae, Semen Platycladi, decoct with water respectively, amount of water is 10 times of quality of medicinal material, extracts each 2 hours 2 times;
(2) merge above-mentioned decocting liquid, filter, filtrate is concentrated into the extractum of relative density 1.20 (60 ℃);
(3) adding 95% ethanol (volume mass mark) in extractum is 60% (volume mass mark) to containing the alcohol amount, leaves standstill 24 hours; Get supernatant, filter, reclaim ethanol, being concentrated into relative density is the thick paste of 1.30 (60 ℃).
(4) with equivalent extract at 60～80 ℃ of following drying under reduced pressure, pulverized 80 mesh sieves, add dry granulation behind the 5% dextrin mixing, granulate, granule.(granulation, granulate are common process)
The Chinese medicine preparation (capsule) of embodiment 2 preparation treatment cardiopalmus
Prescription is: Rhizoma Coptidis 10 grams, Radix Sophorae Flavescentis 14 grams, Radix Angelicae Sinensis 14 grams, Radix Rehmanniae 17 grams, Semen Ziziphi Spinosae 35 grams, Semen Platycladi 25 grams (potion).
Preparation method is:
(1) get Rhizoma Coptidis, Radix Sophorae Flavescentis, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Ziziphi Spinosae, Semen Platycladi, decoct with water respectively, amount of water is 10 times of quality of medicinal material, extracts each 2 hours 2 times;
(2) merge above-mentioned decocting liquid, filter, filtrate is concentrated into the extractum of relative density 1.20 (60 ℃);
(3) adding 95% ethanol (volume mass mark) in extractum is 60% (volume mass mark) to containing the alcohol amount, leaves standstill 24 hours; Get supernatant, filter, reclaim ethanol, being concentrated into relative density is the thick paste of 1.30 (60 ℃).
(4) with equivalent extract at 60～80 ℃ of following drying under reduced pressure, pulverized 80 mesh sieves, add dry granulation behind the 5% dextrin mixing, granulate incapsulates granule, makes capsule.
The Chinese medicine preparation (tablet) of embodiment 3 preparation treatment cardiopalmus
Prescription is: Rhizoma Coptidis 13 grams, Radix Sophorae Flavescentis 11 grams, Radix Angelicae Sinensis 16 grams, Radix Rehmanniae 16 grams, Semen Ziziphi Spinosae 40 grams, Semen Platycladi 20 grams.
Preparation method is with embodiment 1, but pulverizes 80 mesh sieves at last, obtain drug powder after, add conventional adjuvant, make tablet.
The Chinese medicine preparation (pill) of embodiment 4 preparation treatment cardiopalmus
Prescription is: Rhizoma Coptidis 9 grams, Radix Sophorae Flavescentis 15 grams, Radix Angelicae Sinensis 12 grams, Radix Rehmanniae 18 grams, Semen Ziziphi Spinosae 30 grams, Semen Platycladi 30 grams.
Preparation method is with embodiment 1, but pulverizes 80 mesh sieves at last, obtain drug powder after, add conventional adjuvant, make pill.
The Chinese medicine preparation (granule) of embodiment 5 preparation treatment cardiopalmus
Prescription is: Rhizoma Coptidis 15 grams, Radix Sophorae Flavescentis 9 grams, Radix Angelicae Sinensis 18 grams, Radix Rehmanniae 15 grams, Semen Ziziphi Spinosae 45 grams, Semen Platycladi 15 grams.
Preparation method is with embodiment 1.
Clinical data
Case 1 king so-and-so, man, 31 years old, 2004-08-05 first visit.
Main suit: in nervous January, increase the weight of a week.
Symptom: the patient occurred nervous before January, be persistence, and is moving then increase the weight of.Once in certain hospital admission, be ECG and showed: the existing premature beat in arrhythmia-room.But do not give regular treatment.The sx of having palpitation in a nearly week comes the inventor to locate outpatient service for asking further treatment.Existing patient is nervous, is persistence, movable back shortness of breath and fatigue, flushed complexion, the xerostomia order is puckery, five tidal surge of emotion heat, two cheekbones are rubescent, receive can, little sleep disturbed by dreams, urine is transferred, big dry stool.
The tongue arteries and veins: red tongue, yellow and thin fur, thready and rapid pulse, the knot generation.
History of past illness: 10 years provirus property myocarditis medical histories.
Auxiliary examination: EKG shows: arrhythmia-artrial premature beat takes place frequently.
Diagnosis: arrhythmia-artrial premature beat.
Handle: take embodiment 1 drug prepared, every day, potion was taken 7 days.
The 2004-08-12 further consultation:
Symptom: the patient still has nervous symptom, and time ends when sending out, and the twinge of idol companion's breast is not relaxed, and diseases such as flushed complexion, xerostomia obviously alleviate, dysphoria with feverish sensation in the chest palms and soles still, and hectic fever night sweat, two cheekbones are rubescent, but make moderate progress.Receive can, sleep to improve, urine is transferred, stool slightly does.
EKG shows: arrhythmia-artrial premature beat takes place frequently.
The tongue arteries and veins: red tongue, thin fur, little Huang, thready pulse, the knot generation.
Handle: take embodiment 1 drug prepared, every day, potion was taken 7 days.
The 2004-08-19 further consultation:
Symptom: nervous further alleviate, chest pain disappears, and does not have five tidal surge of emotion heat, and two cheekbones are rubescent, and flushed complexion, xerostomia are alleviated, poor appetite, the time feel sick, acid regurgitation, dormancy can, two just transfer.
The tongue arteries and veins: red tongue, white and thin fur, thready pulse, the knot generation.
Handle: take embodiment 1 drug prepared, every day, potion was taken 7 days.
The 2004-08-26 further consultation:
Symptom: accidentally have palpitation surplus no significant discomfort.Receive sleep can, two just transfer.
The tongue arteries and veins: light red tongue, white and thin fur, thready pulse, the knot generation.
Handle: take embodiment 1 drug prepared, every day, potion was taken 7 days.
Pay a return visit: pay a return visit no sense of discomfort after March.Repeatedly checking EKG shows: normal range electrocardiogram.
Case 2 grandsons so-and-so, man 55 years old, the 2005-01-08 first visit.
Main suit: ictal March uncomfortable in chest, nervous.
Symptom: the patient feel nearly March ictal uncomfortable in chest, have palpitation, breathe hard, the pulse of testing oneself has intermittently, once in certain hospital admission, is diagnosed as frequent premature ventricualr contraction.Take metoprolol, 12.5mgbid, effect is undesirable.Existing patient ictal uncomfortable in chest, have palpitation, breathe hard, fatigue and weakness, few moving lazy speech, dysphoria with feverish sensation in the chest palms and soles, hectic fever, night sweat, flushed cheeks, it is poor to sleep, yellowish or reddish urine, constipation, defecation inability.
Tongue arteries and veins: red tongue with thin and yellow fur, irregularly intermittent and regularly intermittent pulse.
Auxiliary examination: EKG shows: ventricular premature contraction takes place frequently.
Diagnosis: arrhythmia-ventricular premature contraction takes place frequently
Handle: take embodiment 2 drug prepared, every day, potion was taken 6 days.
The 2005-01-14 further consultation
The main suit: uncomfortable in chestly, nervous before alleviate, the more preceding minimizing of premature beat attack times is still breathed hard, fatigue and weakness, but before alleviate.Dysphoria with feverish sensation in the chest palms and soles, hectic fever, night sweat, the flushed cheeks symptom obviously alleviates.Receive can, the difference of sleeping dreaminess, little Huang of urinating, constipation, defecation inability.
Tongue arteries and veins: red tongue with thin and yellow fur, irregularly intermittent and regularly intermittent pulse.
Handle: take embodiment 2 drug prepared, every day, potion was taken 6 days.
The 2005-01-20 further consultation
The main suit: uncomfortable in chest, nervous more precedingly obviously alleviate, the more preceding minimizing of premature beat attack times is breathed hard, and fatigue and weakness obviously alleviates.No dysphoria with feverish sensation in the chest palms and soles, hectic fever, night sweat, flushed cheeks symptom.Receive can, it is poor to sleep, two just transfer.
Tongue arteries and veins: red tongue with thin fur, irregularly intermittent and regularly intermittent pulse.
Handle: take embodiment 2 drug prepared, every day, potion was taken 6 days.
Pay a return visit: pay a return visit after February, nervous, transference cure uncomfortable in chest do not have uncomfortable.
Case 3 grandsons so-and-so, man, 63 years old, 2008-10-15 first visit.
Main suit: weak 1 month of nervous companion.
Symptom: the patient is the nervous symptom of no obvious inducement appearance before January, and movable back sees not have dizziness, headache more, do not have to feel sick, vomiting, symptoms such as no uncomfortable in chest, chest pain, it is conscious listless to show the patient, malaise, with two lower limb for very, surplus no significant discomfort, poor appetite, loss of appetite, dormancy can, big dry stool, a few days delegation, urine is transferred.
Tongue arteries and veins: light red tongue yellow fur, thready pulse.
History of past illness: hypertension medical history 10 years, be up to 180/105mmHg, oral amlodipine, perindopril control, blood pressure is in normal range.
Auxiliary examination: auxiliary examination: Holter shows: (08-10-6 is in Shandong hospital) shows: 1, multiple premature ventricular beat, idol are in pairs.2, the atrial premature beat that takes place frequently, a short battle array room speed.The no abnormal dynamic change of 3ST section, low flat inversion of T ripple.EKG (08-10-7 is in certain hospital): 1, under the old, the rear wall myocardial infarction, 2, ST-T changes.
Diagnosis: 1, under coronary heart disease-old, rear wall myocardial infarction 2, the arrhythmia-ventricular premature contraction that takes place frequently, the artrial premature beat that takes place frequently, the time be a short battle array room speed 3, hypertension (3 grades, high danger).
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
The 2008-10-22 further consultation:
The main suit: medical history is the same, patient's private prosecution back lower limb transference cure of aching of taking medicine, the weak doing well,improving that waits, still have nervous, receive sleep can, big dry stool, about 3 days delegation, urine is transferred.
Tongue arteries and veins: the dark yellow fur of tongue, deep-thready pulse.
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
The 2008-10-29 further consultation:
The main suit: medical history is the same, patient's nervous sx in back of taking medicine, weak symptom disappears substantially, receive sleep can, two just transfer.
The tongue arteries and veins: red tongue, tongue is white, deep-thready pulse.
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
Pay a return visit: pay a return visit after February, patient's transference cure of have palpitation still feels weak, surplus nothing discomfort after the activity.
Case 4 kings so-and-so, woman, 61 years old, 2009-10-22 first visit.
Main suit: ictal nervous 5 years, increase the weight of half a year.
Symptom: the patient before 5 years no obvious inducement occur ictal nervously, occur during more than rest,, be diagnosed as " coronary heart disease, ventricular premature contraction takes place frequently " in local hospital admission, do not give attention; Nervous sx before half a year, outbreak is frequent, no chest pain, dizziness, moving usually then sensation of oppression over the chest with shortness of breath, spontaneous perspiration, weak, dizziness, dim complexion, receive sleep can, two just accent.
The tongue arteries and veins: tongue is dark red, and tongue is greasy in vain, and stringy pulse is tied generation.
Auxiliary examination: Holter shows: the ventricular premature contraction that takes place frequently, 7927 times/24h, the T ripple is low flat.
Diagnosis: 1, arrhythmia-ventricular premature contraction 2, coronary heart disease take place frequently.
Treatment: take embodiment 1 drug prepared, every day, potion was taken 6 days.
The 2009-10-29 further consultation:
The main suit: patient's symptom such as have palpitation, breathe hard before alleviates, and still has dizziness, weak, nauseating, sweating, receive sleep can, two just transfer.
The tongue arteries and veins: red tongue, tongue are greasy in vain, stringy and thready pulse.
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
The 2009-11-05 further consultation:
The main suit: patient's nervous symptom such as breathe hard in back of taking medicine obviously alleviates, and does not have dizzy, weak, nauseating, sweating, receive dormancy can, two just accent.
The tongue arteries and veins: the red tongue tongue is white, thready pulse.
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
Pay a return visit: pay a return visit after February, nervous symptom appears in patient again, breathes hard, symptom such as spontaneous perspiration also significantly improves.
Case 5 kings so-and-so, man, 71 years old, 2010-10-22 first visit.
Main suit: in year surplus in the of nervous 10, increase the weight of January.
Symptom: the patient did not have obvious inducement and occurs having palpitation before 10 years, and idol has uncomfortable in chest, tachypnea, no chest pain, headache, and idol has dizziness, does not give systematic treating always, is diagnosed as ventricular premature contraction in community clinic.Before January, patient's sx of having palpitation, take the commentaries on classics of not getting better after the Drug therapys such as metoprolol, WENXIN KELI, heart nourishing, gave " amiodarone " 0.2g bid treatment back remission before 12 days, existing patient still feels nervous, uncomfortable in chest, heaviness of the head as if it were tightly bandaged, the vomiting sputum, receive can, it is poor to sleep, dreaming often and waking easily, two just transfer.
The tongue arteries and veins: purplish tongue is dim, and tongue is greasy in vain, thready pulse.
History of past illness: hypertension medical history 6 years, be up to 180/95mmHg, take metoprolol, compound Herba Apocyni veneti (Folium Apocyni Veneti), controlling of blood pressure is undesirable.
Auxiliary examination: Holter shows: the ventricular premature contraction that takes place frequently, the time be premature ventricular beat, 1947 times/24h.
Diagnosis: 1, the arrhythmia-ventricular premature contraction 2 that takes place frequently, hypertension (3 grades of high danger).
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
The 2010-10-29 further consultation:
The main suit: medical history is the same, patient's nervous sx in back of taking medicine, no uncomfortable in chest, chest pain does not have dizzy, headache, receive can, it is poor to sleep, two just accent.
The tongue arteries and veins: tongue is dark red, and tongue is greasy in vain, thready pulse.
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
The 2010-11-05 further consultation:
The main suit: medical history is the same, and patient's nervous symptom in back of taking medicine obviously alleviates, the more preceding improvement of sleep, receive can, two just accent.
The tongue arteries and veins: tongue is dark red, and tongue is white, thready pulse.
Handle: take embodiment 1 drug prepared, every day, potion was taken 6 days.
Pay a return visit: pay a return visit patient's transference cure of having palpitation, no significant discomfort after February.
Claims (7)
1. a Chinese medicine preparation for the treatment of cardiopalmus is characterized in that, is made by following bulk drugs: 9～15 parts of Rhizoma Coptidis, 9～15 parts of Radix Sophorae Flavescentiss, 12～18 parts of Radix Angelicae Sinensis, 15～18 parts of Radix Rehmanniae, 30～45 parts of Semen Ziziphi Spinosaes, 15～30 parts of Semen Platycladi.
2. a kind of Chinese medicine preparation for the treatment of cardiopalmus according to claim 1 is characterized in that: made by following bulk drugs: 12 parts of Rhizoma Coptidis, 12 parts of Radix Sophorae Flavescentiss, 15 parts of Radix Angelicae Sinensis, 16 parts of Radix Rehmanniae, 38 parts of Semen Ziziphi Spinosaes, 22 parts of Semen Platycladi.
3. a kind of Chinese medicine preparation for the treatment of cardiopalmus according to claim 1 is characterized in that: made by following bulk drugs: 10 parts of Rhizoma Coptidis, 14 parts of Radix Sophorae Flavescentiss, 14 parts of Radix Angelicae Sinensis, 17 parts of Radix Rehmanniae, 35 parts of Semen Ziziphi Spinosaes, 25 parts of Semen Platycladi.
4. a kind of Chinese medicine preparation for the treatment of cardiopalmus according to claim 1 is characterized in that: made by following bulk drugs: 13 parts of Rhizoma Coptidis, 11 parts of Radix Sophorae Flavescentiss, 16 parts of Radix Angelicae Sinensis, 16 parts of Radix Rehmanniae, 40 parts of Semen Ziziphi Spinosaes, 20 parts of Semen Platycladi.
5. a kind of Chinese medicine preparation for the treatment of cardiopalmus according to claim 1 is characterized in that: made by following bulk drugs: 9 parts of Rhizoma Coptidis, 15 parts of Radix Sophorae Flavescentiss, 12 parts of Radix Angelicae Sinensis, 18 parts of Radix Rehmanniae, 30 parts of Semen Ziziphi Spinosaes, 30 parts of Semen Platycladi.
6. a kind of Chinese medicine preparation for the treatment of cardiopalmus according to claim 1 is characterized in that: made by following bulk drugs: 15 parts of Rhizoma Coptidis, 9 parts of Radix Sophorae Flavescentiss, 18 parts of Radix Angelicae Sinensis, 15 parts of Radix Rehmanniae, 45 parts of Semen Ziziphi Spinosaes, 15 parts of Semen Platycladi.
7. each described a kind of preparation method for the treatment of the Chinese medicine preparation of cardiopalmus among the claim 1-6 is characterized in that step is as follows:
(1) get Rhizoma Coptidis, Radix Sophorae Flavescentis, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Ziziphi Spinosae, Semen Platycladi, decoct with water respectively, amount of water is 8～12 times of quality of medicinal material, extracts each 1～2 hour 1～3 time;
(2) merge above-mentioned decocting liquid, filter, it is 1.19～1.20 extractum that filtrate is concentrated into relative density;
(3) adding 95% ethanol in extractum is 60% to containing the alcohol amount, leaves standstill 24 hours; Get supernatant, filter, be concentrated into relative density and be the thick paste more than 1.30;
(4) with equivalent extract at 60～80 ℃ of following drying under reduced pressure, pulverized 80 mesh sieves, drug powder, add conventional excipient substance, make tablet, granule, capsule or pill.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142768A (en) * | 2013-03-28 | 2013-06-12 | 重庆市畜牧科学院 | Anti-stress biostime traditional Chinese medicine composition for piglets and preparation method of traditional Chinese medicine composition |
| CN104027612A (en) * | 2013-03-07 | 2014-09-10 | 曹克强 | Traditional Chinese medicine preparation for treating arrhythmia |
| CN104825732A (en) * | 2015-05-05 | 2015-08-12 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating palpitaition |
| CN115105564A (en) * | 2021-03-19 | 2022-09-27 | 苏州玉森新药开发有限公司 | Traditional Chinese medicine composition for treating arrhythmia and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634206A (en) * | 2003-12-26 | 2005-07-06 | 王保安 | Capsule for treating heart palpitation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1634206A (en) * | 2003-12-26 | 2005-07-06 | 王保安 | Capsule for treating heart palpitation |
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| Title |
|---|
| 《山东中医杂志》 20040220 薛梅等 中医药治疗快速性心律失常近况 123-125 1-7 第23卷, 第02期 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104027612A (en) * | 2013-03-07 | 2014-09-10 | 曹克强 | Traditional Chinese medicine preparation for treating arrhythmia |
| CN103142768A (en) * | 2013-03-28 | 2013-06-12 | 重庆市畜牧科学院 | Anti-stress biostime traditional Chinese medicine composition for piglets and preparation method of traditional Chinese medicine composition |
| CN103142768B (en) * | 2013-03-28 | 2015-02-18 | 重庆市畜牧科学院 | Anti-stress biostime traditional Chinese medicine composition for piglets and preparation method of traditional Chinese medicine composition |
| CN104825732A (en) * | 2015-05-05 | 2015-08-12 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating palpitaition |
| CN115105564A (en) * | 2021-03-19 | 2022-09-27 | 苏州玉森新药开发有限公司 | Traditional Chinese medicine composition for treating arrhythmia and preparation method and application thereof |
| CN115105564B (en) * | 2021-03-19 | 2023-10-20 | 苏州玉森新药开发有限公司 | Traditional Chinese medicine composition for treating arrhythmia and preparation method and application thereof |
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