CN102274580A - Electrical stimulated therapeutic instrument and application method thereof - Google Patents
Electrical stimulated therapeutic instrument and application method thereof Download PDFInfo
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- CN102274580A CN102274580A CN2011101253460A CN201110125346A CN102274580A CN 102274580 A CN102274580 A CN 102274580A CN 2011101253460 A CN2011101253460 A CN 2011101253460A CN 201110125346 A CN201110125346 A CN 201110125346A CN 102274580 A CN102274580 A CN 102274580A
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Abstract
The invention discloses an electrical stimulated therapeutic instrument which comprises working circuits and electrodes. The working circuits possess a first current output circuit and a second current output circuit. The electrodes comprise a first group of electrodes and a second group of electrodes. The first group of electrodes is connected with an output terminal of the first current output circuit. The second group of the electrodes is connected with the output terminal of the second current output circuit. The invention also discloses a method of using the electrical stimulated therapeutic instrument to treat spiritual and mental illnesses, such as depression, anxiety, mania and insomnia.
Description
Technical field
The present invention relates to the electronic medical instruments technical field.
Background technology
It is unhappy to it has been recognized that problems such as depression, anxiety, mad dry, insomnia can not be interpreted as simply, and should go from the category of mental sickness and mental illness to treat and treat.At these diseases, have and carry out Drug therapy, also have and carry out traditional Chinese medical science traditional remedies, the electronic stimulation that utilizes electronic therapeutic instrument to implement has also appearred now.
For example, a kind of instrument---CES that can treat depressed and anxiety that it is said has appearred in the U.S., and its single channel output frequency is 0.5Hz or 100Hz (putting mutually with switch), and sites of electrostimulation is with electrode clip ear-lobe.Also having the depressed electrical stimulation apparatus of another kind of treatment that wound is then arranged, is the electronic installation of a similar heart pacemaker, in its implanted patient's body, by its constantly electric shock stimulate the vagus nerve of patient's brain, thereby alleviate depression symptom effectively.
Sieve of Beijing mental health institute and spring etc. have studied one specially at the electric acupuncture apparatus of depression treatment, and single channel output stimulates hundred to converge and the space between the eyebrows two caves simultaneously, and electrode is to thrust two acupuncture points with acupuncture needle, and it is not quite clear specifically to export electrical quantity.
A kind of electric shock therapy is arranged, depress at 80～100 voltaisms, electric current is the brain by the people directly, to reach therapeutic purposes.This method is generally carried out under anesthesia, and being divided into has tic and do not have the tic method.Whole body is twitched when having tic promptly to switch on, and not having tic is that health is not twitched.This method is to being had side effect in various degree by therapist.
Existing electric acupuncture apparatus and electrical stimulation apparatus can frequency modulation, but can not accurately regulate, and just can know the accurate frequency of being transferred by the frequency measurement instrument.
Summary of the invention
The objective of the invention is to obtain the extremely low treatment depression of one efficient, noinvasive, side effect and the treatment and the auxiliary treatment equipment of anxiety neurosis.
In order to reach the foregoing invention purpose, the present invention has adopted following technical scheme: a kind of electric stimulation therapeutic apparatus, comprise operating circuit and electrode, and described operating circuit has first current output circuit and second current output circuit; Reach described electrode and be made up of first group of electrode and second group of electrode, described first group of electrode is connected with the outfan of first current output circuit, and described second group of electrode is connected with the outfan of second current output circuit.
Wherein, the output frequency of described first current output circuit is 5～150Hz; The output frequency of described second current output circuit is 0.1～6Hz.
Further, described operating circuit has first insulating power supply and second insulating power supply, the input of described first current output circuit is connected with the outfan of first insulating power supply, and the input of described second current output circuit is connected with the outfan of second insulating power supply.
As optimal way, described first insulating power supply and second insulating power supply are the DC/DC insulating power supply.
Further, described operating circuit has a power module and a control circuit, and described control circuit is electrically connected with power module, and described first current output circuit of signal controlling and second current output circuit.
As optional mode, described first group of electrode and second group of electrode are for thrusting formula electrode or the non-formula electrode that thrusts.
Another object of the present invention is to use the method for above-mentioned electric stimulation therapeutic apparatus as the therapeutic equipments of treatment depression, anxiety, mad dry, the spirit of having a sleepless night and mental illness, this method may further comprise the steps:
(A) two counter electrode of described electric stimulation therapeutic apparatus are placed respectively on two pairs of acupuncture points;
(B) two counter electrode adopt the output frequency of 5～150Hz respectively, and the output frequency of 0.1～6Hz, simultaneously energising.
As a kind of preferred version, described two pairs of acupuncture points are SANYINJIAO acupoint, pass to the electric current of the output frequency of 0.1～6Hz; Reach TAICHONG acupoint, pass to the electric current of the output frequency of 5～150Hz.
The power frequency of two counter electrode is preferably SANYINJIAO acupoint 0.5Hz, TAICHONG acupoint 25Hz.
The present invention is by adopting said structure, and its two arrays of electrodes is electrically connected on two current output circuits respectively, and is arranged on simultaneously on two acupuncture points and carries out electronic stimulation, simple effectively, safety and side effect be extremely low.And this adopts the form of two independent current output circuit, can reduce crosstalking of two-way different frequency circuit.
Electric stimulation therapeutic apparatus of the present invention has simply effective and safe therapeutic effect as the therapeutic equipments of spirit such as treatment depression, anxiety, mad dry, insomnia and mental illness by provable its of animal experiment contrast, and its effect is better than existing technology.Use this instrument--adopt under the situation of optimized frequency, carried out 10 routine clinical trials, carried out for six weeks altogether, obtain following therapeutic outcome (seeing Table 1):
Table 1: the HAMD of various treatment meanss subtracts the branch rate.Data are percentage rate (%) in the table
In the last table, common drug is meant all antidepressant drugs of the existing SSRIs of comprising class medicine and venlafaxine; SSRIs class medicine is a most popular now line antidepressant drug; Venlafaxine is existing fastest antidepressant drug (negative interaction is also quite big).Wherein, the above-mentioned branch rate that subtracts is weighted mean.That is: p=∑ (pi*ni)/∑ ni; What pi and ni were respectively each sample subtracts branch rate and sample number.N=∑ ni, i.e. total sample number.The branch rate that subtracts of each sample is according to the mean value calculation of the day part of each sample.
The HAMD score value is high more, illustrates that depressed degree is serious more, and is low more then more near normal level.Clinical cure is defined as HAMD (17) scoring≤7 minutes, or HAMD subtracts branch rate 〉=75%.In other words, it is high more that HAMD subtracts the branch rate, illustrates that therapeutic effect is remarkable more.When first week, there are 2 examples to reach the effect of clinical cure in 10 examples of employing therapeutic instrument.HAMD is respectively: be respectively before the treatment 24 and 22 fens, be respectively for first weekend 6 and 5 fens.Added up the case (total routine number is 1115 examples) of the use common drug treatment of disclosed report, having only has 2 examples (not having concrete data) to reach clinical cure in 28 examples in certain clinical trial.
From last table as seen, use the therapeutic instrument treatment, the branch rate that subtracts of HAMD surmounts the other medicines therapeutic effect far away promptly up to 40.46% in first week.In second, four, six weeks subsequently, the branch rate that subtracts of HAMD is also up to 47.40%～62.72%.Hence one can see that, and therapeutic instrument more can quick acting than medicine, particularly when first week.The meaning of quick acting is: the misery that alleviates patient fast; Can reduce the danger of patient's financial burden and suicide; Improve the treatment confidence of depressive patients, improve patient's compliance the doctor.
For side effect, when this therapeutic instrument of application carries out electronic stimulation, in the first secondary therapeutic process slight dizzy phenomenon may appear, and very fast disappearance after time treatment is finished.Follow-up treatment dizzy phenomenon can not occur again.And by contrast, take medicine, the appetite that can occur continuing descends, feels sick, dizziness, xerostomia, diarrhoea, cardiopalmus, constipation, weak, Glutamate pyruvate transaminase rises, blurred vision, drowsiness, gastrointestinal reaction, erythra, insomnia, dysuria, intense, tremble, ECG change, abdominal distention etc.30%--90% among the medication person can produce or multinomial side effect in above-mentioned.
As seen, this therapeutic instrument is a kind of rapid-action, the anti depressant therapy equipment that side effect is extremely low.
Description of drawings
Fig. 1 is a circuit structure block chart of the present invention.
Among the figure:
The 10-input voltage; 21-first insulating power supply; 22-second insulating power supply; 31-first current output circuit; The 32-second electric current output current; First group of electrode of 41-; Second group of electrode of 42-; The 50-control circuit; The 60-power module.
Fig. 2 is that the power frequency that acts on TAICHONG acupoint immobilizes under the situation, opens wild test score curve chart when acting on SANYINJIAO acupoint acupuncture point power frequency and changing.
Fig. 3 is under the power frequency that acts on SANYINJIAO acupoint immobilizes situation, and the score curve chart is tested in the open country of opening when acting on the power frequency variation of TAICHONG acupoint acupuncture point.
When Fig. 4 is the selected respectively 0.5Hz frequency of the electric current that acts on SANYINJIAO acupoint or TAICHONG acupoint, when changing, opens another acupuncture point power frequency the change curve of wild test score.
Now in conjunction with the accompanying drawings and embodiments the present invention is described in further detail:
The specific embodiment
As shown in Figure 1, electric stimulation therapeutic apparatus of the present invention, mainly comprise electrode and operating circuit, described operating circuit mainly is made up of first insulating power supply 21, second insulating power supply 22, first current output circuit 31, second current output circuit 32, control circuit 50 and power module 60.Described electrode is made up of first group of electrode 41 and second group of electrode 42.This first insulating power supply 21 and second insulating power supply 22 are the DC/DC insulating power supply.
The input of first insulating power supply 21, second insulating power supply 22 and power module 60 is connected with input voltage 10 respectively; The input of first current output circuit 31 is connected with the outfan of first insulating power supply 21, and its outfan then connects first group of electrode 41; The input of second current output circuit 32 is connected with the outfan of second insulating power supply 22, and its outfan then connects second group of electrode 42; Control circuit 50 is electrically connected and exports control signal to control the circuit parameter of first current output circuit 31 and second current output circuit 32 with power module 60, and handle feedback signal from first current output circuit 31 and second current output circuit 32, this feedback signal is mainly the power frequency of two current output circuits.First group of electrode 41 is connected with the outfan of first current output circuit 31, and second group of electrode 42 is connected with the outfan of second current output circuit 32.First group of electrode 41 and second group of electrode 42 are fixed in by on the acupuncture point of therapist for thrusting formula electrode or the non-formula electrode that thrusts.
The mode of the circuit parameter of above-mentioned control circuit control current output circuit can adopt existing conventional treatment mode, form by oscillating circuit and voltage as current output circuit, regulate the output current frequency of the vibration coefficient of oscillating circuit by control circuit with the control voltage.And for example current output circuit is made up of crystal oscillator+frequency dividing circuit and voltage (containing control module), regulates the output current frequency of the divide ratio of crystal oscillator+frequency dividing circuit with the control voltage by control circuit, or the like.
When the present invention uses, first group of electrode and second group of electrode are individually fixed in by on two groups of acupuncture points of the same name of therapist, be fixed in by the TAICHONG acupoint position (bilateral) of therapist as first group of electrode, second group of electrode is fixed in by the sanyinjiao point of therapist (bilateral).Starting instrument exports the two-way electric current simultaneously, the first current output circuit output frequency is that the electric current of a certain fixed frequency between 5～150Hz acts on TAICHONG acupoint position (bilateral) by first group of electrode, making the second current output circuit output frequency is that the electric current of a certain fixed frequency between 0.1～6Hz acts on sanyinjiao point (bilateral) by second group of electrode, thereby to being played excellent curative by the depression of therapist, anxiety neurosis or other psychiatric department disease.According to evidence, the optimized frequency of two electrode output currents is combined as TAICHONG acupoint 25Hz, sp 6 0.5Hz.The frequency of two arrays of electrodes output current and the time of output current can be set by control circuit.
Two current output circuits of the present invention provide electric power by insulating power supply independently respectively, can remove in the electrical network triple-frequency harmonics and reduce interfering signal and moment surge, avoid causing the equipment operation undesired because power supply is bad.The current waveform distortion (as triple-frequency harmonics) that nonlinear load causes can not polluted electrical network by isolation, avoids having influence on the operate as normal of alternating current power supply and electrical network is produced pollution, plays the effect that purifies electrical network; When human body because when touching hot base plate, will make electric current pass through human body and the earth formation loop, causing the harm of getting an electric shock, if use insulating power supply, will because primary and secondary is by the magnetic field positive energy exchange, there be hard connection physically more safely, even if human body touches charged article, can be electronegative potential and make the current potential at charged position also, can not cause the harm of getting an electric shock because of human body and the earth coequality.Therefore for the occasion of its application, have more safe, reliable, stable advantage.
Embodiment 1
This example is that the best of breed that acts on the acupuncture point is screened.
Select seven acupuncture points commonly used of treatment depression, connected valleys, the space between the eyebrows, Nei Guan, Shenmen, Baihui, sp 6, Tai Chong.Press C
7 1, C
7 2, C
7 3, C
7 4, C
7 5, C
7 6, C
7 7, number of combinations be 7,21,35,35,21,7,1 totally 127 kinds of acupuncture point compound modes carry out the depressed rat treatment of chronic stress experiment, fixed-frequency as a result of detects to open wild test at 2Hz.The results are shown in following table 2:
Table 2
| Number of rats | Open wild result of the test (on average) | The acupuncture point combination | |
| On average | 1270 | 20.45 | All combinations |
| Best | 10 | 53.2 | Dash very much-sp 6 |
| Inferior good | 10 | 33.6 | Dash very much-connected valleys |
The wild test method of opening that the present invention adopts is: spacious case, and height is 40cm, and length and width respectively are 80cm, and perisporium is a black, and the bottom surface is made up of 25 squares that area equates.Passing through the bottom surface number of squares with animal is the horizontal movement score, and whenever passing through lattice is one minute.Counted three minutes, mark is high more, and depressed degree is low more.
Result of the test shows, dashes very much-combination the best of sp 6.
Embodiment 2
This example is that electrical stimulation parameters is screened.
Selected dash very much-acupuncture point of sp 6 is combined into the line frequency composite test.Institute's selected frequency is: 0.5Hz, 2Hz, 5Hz., dash very much-sp 6 selects for use said frequencies to make up in twos respectively, and totally 9 combinations are tested.Result such as Fig. 2, shown in Figure 3.Among the figure, vertical coordinate is for opening wild test score, and abscissa is that frequency is adopted at the acupuncture point.No matter SANYINJIAO acupoint or TAICHONG acupoint, when adopting the 0.5Hz frequency, when the frequency that adopt at another acupuncture point changes, can be along with the increase of power frequency numerical value, therapeutic effect can become and become better and better.And the best of breed that herein shows is: SANYINJIAO acupoint 0.5Hz, TAICHONG acupoint 5Hz.
Embodiment 3
When sp 6 or too towards selecting the 0.5Hz frequency respectively, and another acupuncture point selects a frequency among 5Hz, 15Hz, 25Hz, 100Hz, the 150Hz to test respectively, the result as shown in Figure 4, can see, after SANYINJIAO acupoint or TAICHONG acupoint were selected the action current of 0.5Hz frequency respectively, its therapeutic effect all can increase along with the frequency at another acupuncture point and become excellent.But during the selected 0.5Hz of SANYINJIAO acupoint, along with the increase of TAICHONG acupoint institute selected frequency, when its therapeutic effect value added is much better than the selected 0.5Hz of TAICHONG acupoint, the effect that increases along with the increase of SANYINJIAO acupoint institute selected frequency.
The present invention is not limited to above-mentioned embodiment, if various changes of the present invention or modification are not broken away from the spirit and scope of the present invention, if these are changed and modification belongs within claim of the present invention and the equivalent technologies scope, then the present invention also is intended to comprise these changes and modification.
Claims (9)
1. electric stimulation therapeutic apparatus comprises operating circuit and electrode, it is characterized in that, described operating circuit has first current output circuit and second current output circuit; Reach described electrode and be made up of first group of electrode and second group of electrode, described first group of electrode is connected with the outfan of first current output circuit, and described second group of electrode is connected with the outfan of second current output circuit.
2. electric stimulation therapeutic apparatus according to claim 1 is characterized in that, the output frequency of described first current output circuit is 5～150Hz; The output frequency of described second current output circuit is 0.1～6Hz.
3. electric stimulation therapeutic apparatus according to claim 1 and 2, it is characterized in that, described operating circuit has first insulating power supply and second insulating power supply, the input of described first current output circuit is connected with the outfan of first insulating power supply, and the input of described second current output circuit is connected with the outfan of second insulating power supply.
4. electric stimulation therapeutic apparatus according to claim 3 is characterized in that, described first insulating power supply and second insulating power supply are the DC/DC insulating power supply.
5. electric stimulation therapeutic apparatus according to claim 1, it is characterized in that, described operating circuit has a power module and a control circuit, and described control circuit is electrically connected with power module, and described first current output circuit of signal controlling and second current output circuit.
6. electric stimulation therapeutic apparatus according to claim 1 is characterized in that, described first group of electrode and second group of electrode are for thrusting formula electrode or the non-formula electrode that thrusts.
7. application such as the described electric stimulation therapeutic apparatus of claim 1～6 is characterized in that may further comprise the steps as the method for the therapeutic equipments of treatment depression, anxiety, mad dry, the spirit of having a sleepless night and mental illness:
(A) two counter electrode of described electric stimulation therapeutic apparatus are placed respectively on two pairs of acupuncture points;
(B) two counter electrode adopt the output frequency of 5～150Hz respectively, and the output frequency of 0.1～6Hz, simultaneously energising.
8. method according to claim 7 is characterized in that, described two pairs of acupuncture points are respectively SANYINJIAO acupoint, pass to the output frequency of 0.1～6Hz; Reach TAICHONG acupoint, pass to the output frequency of 5～150Hz.
9. method according to claim 8 is characterized in that the power frequency of two counter electrode is preferably SANYINJIAO acupoint 0.5Hz, TAICHONG acupoint 25Hz.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110354385A (en) * | 2019-07-18 | 2019-10-22 | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | Through the multi-modal electric stimulation therapeutic apparatus of cranium and its application method |
| CN110898333A (en) * | 2019-12-06 | 2020-03-24 | 广东筑宾健康产业有限公司 | Health management instrument for assisting in repairing anxiety and depression and use method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101048100A (en) * | 2004-09-08 | 2007-10-03 | 奥林巴斯株式会社 | Capsule type medical device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101048100A (en) * | 2004-09-08 | 2007-10-03 | 奥林巴斯株式会社 | Capsule type medical device |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110354385A (en) * | 2019-07-18 | 2019-10-22 | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | Through the multi-modal electric stimulation therapeutic apparatus of cranium and its application method |
| CN110898333A (en) * | 2019-12-06 | 2020-03-24 | 广东筑宾健康产业有限公司 | Health management instrument for assisting in repairing anxiety and depression and use method |
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Application publication date: 20111214 |