CN102274153A - Skin-care composite with moisturizing effect - Google Patents
Skin-care composite with moisturizing effect Download PDFInfo
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Abstract
The invention provides a skin-care composite with moisturizing effect. The raw drug in parts by weight comprises 10-30 parts of astragalus mongholicus, 3-10 parts of salvia miltiorrhiza, 4-16 parts of mangnolia officinalis, 3-15 parts of honeysuckle flower, 2-10 parts of liquorice and 3-12 parts of divaricate saposhnikovia root; according to the invention, the thought formula on the composing principles in Chinese traditional medicine is adopted; the astragalus mongholicus, the salvia miltiorrhiza, the mangnolia officinalis, the honeysuckle flower, the liquorice and the varicate saposhnikovia root are selected as the main raw materials; a proper extracting process is designed according to the features of the raw materials, so that the components are combined rationally and cooperated with each other and the effect of lasting moisture is achieved really.
Description
Technical field
The present invention relates to a kind of external skin-care composition, relate in particular to a kind of skin care compositions with moisture-keeping efficacy with the herbal composite preparation.
Background technology
To old, the process of its skin aging also can be described as the process that the skin moisture-keeping type reduces to the people by infant.Skin moisture-keeping mainly is meant the water content of epidermis, particularly cuticular water content, and cuticular water content plays decisive role to the sensation and the outward appearance of skin, and when cuticular water content was sufficient, skin will be soft, smooth, water profit, saturating intelligence.Under the normal condition, the water content of skin accounts for 18%～20% of all water content of human body, and with advancing age, the water content of skin is fewer and feweri.Therefore, using moisture-keeping cosmetics is to keep skin smooth, softness, whippy important channel.A lot of moisture-keeping cosmetics are arranged in the market, of a great variety, effect is different, method for moisturizing commonly used is direct moisturizing or additional lubricant component, with nourishes rough skin, but the shortcoming that this often existence of preserving moisture is cured the symptoms, not the disease, it is instant preserving moisture, can not preserve moisture lastingly, can't fundamentally solve skin problem, play real moistening effect.
Summary of the invention
It is that primary raw material is used for the skin care compositions that daily skin protection has moisture-keeping efficacy with the Chinese medicine extract that technical problem solved by the invention provides a kind of.
Another object of the present invention provides the application of above-mentioned skin care compositions.
Further aim of the present invention provides the preparation method of above-mentioned skin care compositions.
The present invention for achieving the above object, the technical scheme of employing is:
A kind of skin care compositions with moisture-keeping efficacy, crude drug is: counts by weight,
The Radix Astragali 10～30; Radix Salviae Miltiorrhizae 3～10; Cortex Magnoliae Officinalis 4～16; Flos Lonicerae 3～15; Radix Glycyrrhizae 2～10; Radix Saposhnikoviae 3～12.
Skin care compositions of the present invention, crude drug is preferably: counts by weight,
The Radix Astragali 20; Radix Salviae Miltiorrhizae 5; Cortex Magnoliae Officinalis 6; Flos Lonicerae 6; Radix Glycyrrhizae 5; Radix Saposhnikoviae 6.
Skin care compositions of the present invention can be made uses such as water preparation, facial cream, is applied to facial and whole health.Preferred for preparation becomes moisturizer, moisturiser, hand cream, profit body breast, cosmetic water and the elite etc. of preserving moisture.But be not limited to above-mentioned dosage form, can be according to known method in the skin care item industrial circle, described skin care compositions is made various skin care item after by the known method degerming.
Described skin care item preferably further comprise glycerol and/or antiseptic.With the increase moistening effect, and be beneficial to preservation.
The preparation method of skin care compositions of the present invention, step is:
(1) takes by weighing each crude drug respectively according to consumption;
(2) Radix Astragali and Radix Glycyrrhizae are mixed, and Yu Shuizhong soaked 0.5～2 hour, the mass volume ratios of described two flavor crude drug total amounts and water are (0.5～1): (10～30) g/ml, be heated to 80～100 ℃, and be incubated 0.5～2 hour;
(3) Radix Salviae Miltiorrhizae, Cortex Magnoliae Officinalis, Flos Lonicerae and Radix Saposhnikoviae are mixed, and Yu Shuizhong soaked 2～4 hours, the mass volume ratios of described four flavor crude drug total amounts and water are (0.5～1): (15～40) g/ml, be heated to 100 ℃, and be incubated 30 minutes～1 hour;
(4) extracting solution that described step (2) and (3) are obtained carries out coarse filtration respectively, and filtrate is merged;
(5) filtrate that step (4) is obtained is cooled to 30～50 ℃, carries out vacuum filtration, gets filtrate, obtains activity extract.
Coarse filtration is to filter with 200～300 order gauzes in the wherein said step (4).Vacuum filtration is to use plate-and-frame filtration in the wherein said step (5), and vacuum is 0.05～0.1Mpa, and the filter plate fineness is 1～5 micron.Adopt described preparation method can extract active component in the crude drug preferably.
The present invention is to adopt the prescription thought prescription of the traditional Chinese medical science " monarch ".Selecting the Radix Astragali, Radix Salviae Miltiorrhizae, Cortex Magnoliae Officinalis, Flos Lonicerae, Radix Glycyrrhizae and Radix Saposhnikoviae for use is primary raw material.According to the suitable extraction process of material characteristic design, make each component reasonable combination, synergism really reaches the effect of preserving moisture lastingly.The brief introduction of Six-element medical material effect is as follows:
The Radix Astragali: nature and flavor are sweet, warm.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Salviae Miltiorrhizae: bitter in the mouth is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, the amenorrhea dysmenorrhea, breast ventral spine pain, pyretic arthralgia pain, the skin ulcer wound swells and ache dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Cortex Magnoliae Officinalis: bitter in the mouth, suffering, temperature.Return spleen, stomach, lung, large intestine channel.The dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is removed full.Be used for the humidity hysteresis damaging the spleen and stomach, the gastral cavity painful abdominal mass is vomited and diarrhoea, stagnation of QI due to dyspepsia, and abdominal distention constipation, phlegm retention is breathed with cough.
Flos Lonicerae: sweet in the mouth, cold.Return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, wind-heat dissipating.Be used for the carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, warm heating.
Radix Glycyrrhizae: sweet in the mouth is flat.GUIXIN, spleen, lung, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Saposhnikoviae: acrid in the mouth, sweet, warm.Return bladder, liver, spleen channel.Inducing diaphoresis to dispel wind wins and wets, relieving convulsion.Be used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
The traditional Chinese medical science thinks, the gas, blood, the body fluid that run among the meridians are to constitute human body and keep human life activity's material base.Skin covers our whole body, on the one hand by the outer function of defending of oneself, the body interior internal organs is played a protective role, and is the first road barrier of body defence exopathogen; On the other hand, as the whole machine body inalienable part, skin need equally gas, blood, body fluid warm, moisten and moisten foster.Among the present invention, Radix Astragali benefiting QI for strengthening the superficies, the capable then blood of gas is capable, is monarch drug, the Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, the Flos Lonicerae heat-clearing and toxic substances removing, Cortex Magnoliae Officinalis expectorant dampness is removed expectorant, the stasis of blood, wet of skin zone, be ministerial drug, the Radix Saposhnikoviae expelling pathogenic wind from the body surface is dispeled owing to for the moment deficiency of vital energy, opening of sweat pores and is lived in a place other than one's hometown in the external pathogen of flesh table, is adjuvant drug; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, and have the effect of benefiting vital QI and blood, be messenger drug.Benefiting QI for activating blood circulation, dispelling phlegm and eliminating dampness, normal circulation of qi and blood is gone up flourish fur, and dredging the meridian, is induced sweat at heat clearing away, damp eliminating, and skin of face naturally will water profit, fine and smooth, pale, uniform, presents the natural beauty of health, romantic charm U.S..
Skin care compositions of the present invention is to be the external preparation of primary raw material with Chinese medicine, and each medicine combination is according to the method for the invention preparation, and is without any side effects, and skin is not had any stimulation and untoward reaction.
The using method of skin care compositions of the present invention: generally speaking, respectively be coated with once every day sooner or later, is applied to face or health everywhere.
Description of drawings
Fig. 1 tests in the example 2 skin hydration rate change curve in time for the present invention;
Fig. 2 tests in the example 2 skin moisture content change curve in time for the present invention;
Fig. 3 tests in the example 2 the skin rate change curve in time of preserving moisture relatively for the present invention.
The specific embodiment
For further specifying the present invention, specify with the following Examples:
Embodiment 1:
A kind of skin care compositions with moisture-keeping efficacy, the preparation crude drug is:
Radix Astragali 20g, Radix Salviae Miltiorrhizae 5g, Cortex Magnoliae Officinalis 6g, Flos Lonicerae 6g, Radix Glycyrrhizae 5g, Radix Saposhnikoviae 6g;
Method is:
(1) takes by weighing each crude drug respectively according to consumption;
(2) Radix Astragali and Radix Glycyrrhizae are mixed, and Yu Shuizhong soaked 1 hour, the total amount of the Radix Astragali and Radix Glycyrrhizae and the mass volume ratio of water are 1: 20 (g/ml), are heated to 100 ℃, are incubated 1 hour;
(3) Radix Salviae Miltiorrhizae, Cortex Magnoliae Officinalis, Flos Lonicerae and Radix Saposhnikoviae are mixed, and Yu Shuizhong soaked 4 hours, the mass volume ratios of described four flavor crude drug total amounts and water are 1: 30 (g/ml), are heated to 100 ℃, are incubated 30 minutes;
(4) extracting solution that described step (2) and (3) are obtained carries out coarse filtration with 200 order gauzes respectively, and filtrate is merged;
(5) filtrate that step (4) is obtained is cooled to 30 ℃, carries out vacuum sheet frame sucking filtration, and vacuum is 0.1Mpa, and the filter plate fineness is 1 micron, gets filtrate, obtains activity extract.
A kind of skin care compositions with moisture-keeping efficacy, the preparation crude drug is:
Radix Astragali 10g, Radix Salviae Miltiorrhizae 8g, Cortex Magnoliae Officinalis 10g, Flos Lonicerae 9g, Radix Glycyrrhizae 2g, Radix Saposhnikoviae 3g;
Method is:
(1) takes by weighing each crude drug respectively according to consumption;
(2) Radix Astragali and Radix Glycyrrhizae are mixed, and Yu Shuizhong soaked 2 hours, the total amount of the Radix Astragali and Radix Glycyrrhizae and the mass volume ratio of water are 1: 30 (g/ml), are heated to 80 ℃, are incubated 40 minutes;
(3) Radix Salviae Miltiorrhizae, Cortex Magnoliae Officinalis, Flos Lonicerae and Radix Saposhnikoviae are mixed, and Yu Shuizhong soaked 4 hours, the mass volume ratios of described four flavor crude drug total amounts and water are 1: 40 (g/ml), are heated to 100 ℃, are incubated 1 hour;
(4) extracting solution that described step (2) and (3) are obtained carries out coarse filtration with 250 order gauzes respectively, and filtrate is merged;
(5) filtrate that step (4) is obtained is cooled to 50 ℃, carries out vacuum sheet frame sucking filtration, and vacuum is 0.5Mpa, and the filter plate fineness is 5 microns, gets filtrate, obtains activity extract.
Embodiment 3:
A kind of skin care compositions with moisture-keeping efficacy, the preparation crude drug is:
Radix Astragali 15g, Radix Salviae Miltiorrhizae 3g, Cortex Magnoliae Officinalis 16g, Flos Lonicerae 12g, Radix Glycyrrhizae 8g, Radix Saposhnikoviae 9g;
Method is:
(1) takes by weighing each crude drug respectively according to consumption;
(2) Radix Astragali and Radix Glycyrrhizae are mixed, and Yu Shuizhong soaked 0.5 hour, the total amount of the Radix Astragali and Radix Glycyrrhizae and the mass volume ratio of water are 0.5: 20 (g/ml), are heated to 90 ℃, are incubated 0.5 hour;
(3) Radix Salviae Miltiorrhizae, Cortex Magnoliae Officinalis, Flos Lonicerae and Radix Saposhnikoviae are mixed, and Yu Shuizhong soaked 2 hours, the mass volume ratios of described four flavor crude drug total amounts and water are 0.5: 20 (g/ml), are heated to 100 ℃, are incubated 30 minutes;
(4) extracting solution that described step (2) and (3) are obtained carries out coarse filtration with 300 order gauzes respectively, and filtrate is merged;
(5) filtrate that step (4) is obtained is cooled to 40 ℃, carries out vacuum sheet frame sucking filtration, and vacuum is 0.08Mpa, and the filter plate fineness is 3 microns, gets filtrate, obtains activity extract.
A kind of skin care compositions with moisture-keeping efficacy, the preparation crude drug is:
Radix Astragali 25g, Radix Salviae Miltiorrhizae 10g, Cortex Magnoliae Officinalis 4g, Flos Lonicerae 15g, Radix Glycyrrhizae 10g, Radix Saposhnikoviae 12g;
Preparation method is with embodiment 1.
Embodiment 5
A kind of skin care compositions with moisture-keeping efficacy, the preparation crude drug is:
Radix Astragali 30g, Radix Salviae Miltiorrhizae 9g, Cortex Magnoliae Officinalis 8g, Flos Lonicerae 10g, Radix Glycyrrhizae 6g, Radix Saposhnikoviae 10g;
Preparation method is with embodiment 2.
Get activity extract that embodiment 1-5 obtains at last as active effective ingredient, with various adjuvant, preparation method is prepared various skin-protection products routinely, as moisturiser, moisture-retention gel, moisturizer, moisture retention water, hand cream or the like.Can be used for human body face or health everywhere, generally speaking, respectively be coated with once every day sooner or later.The preserving moisture and protecting skin compositions that further proves the application by following test is an effective and safe:
Test example 1: Product Safety evaluation
Human skin patch
1. tried thing: moisturiser
The preparation of moisturiser:
A component: caprylic/capric triglyceride 8g, glyceryl monostearate 2g, stearyl alcohol 5g, shea butter 4g, polydimethylsiloxane 2g, methyl glucose sesquistearate 2g, PEG-20 methyl glucose sesquistearate 2g.
B component: glycerol 4g, butanediol 3g, hyaluronate sodium 0.1g, xanthan gum 0.2g, deionized water 59.4g.
The activity extract 8g that C component: embodiment 1 obtains.
D component: floral perfume 0.1g, Methylisothiazolinone 0.2g.
Preparation method: the A component mixed be heated to 80 ℃, be incubated 20 minutes; The B component mixes and is heated to 80 ℃, is incubated 20 minutes.
The B component is added in the A component, and homogenizing stirs, and 80 ℃ are incubated 10 minutes.
Be cooled to 55 ℃, add the C component.
Be cooled to 45 ℃, add the D component.
Be cooled to 35 ℃, discharging, fill obtains moisturiser.
2. negative control: blank
The preparation of blank sample:
The preparation of moisturiser:
A component: caprylic/capric triglyceride 8g, glyceryl monostearate 2g, stearyl alcohol 5g, shea butter 4g, polydimethylsiloxane 2g, methyl glucose sesquistearate 2g, PEG-20 methyl glucose sesquistearate 2g.
B component: glycerol 4g, butanediol 3g, hyaluronate sodium 0.1g, xanthan gum 0.2g, deionized water 59.4g.
C: floral perfume 0.1g, Methylisothiazolinone 0.2g.
Preparation method: the A component mixed be heated to 80 ℃, be incubated 20 minutes; The B component mixes and is heated to 80 ℃, is incubated 20 minutes.
The B component is added in the A component, and homogenizing stirs, and 80 ℃ are incubated 10 minutes.
Be cooled to 45 ℃, add the C component.
Be cooled to 35 ℃, discharging, fill obtains blank sample.
3. experimenter: totally 30 people, male 0 people, women 30 people in age 21-48 year, meet the experimenter and volunteer inclusion criteria.
4. patch method: select qualified speckle examination device for use, with closed patch test method, to be tried the about 0.020ml～0.025ml of thing (semifluid) drips in speckle examination device, the external special adhesive tape sticks in the experimenter back, remove after 24 hours and tried thing, remove the back respectively and observed dermoreaction in 0.5,24,48 hour, write down its result by dermoreaction grade scale in " cosmetics health standard " (version in 2007).
Result of the test sees Table 1:
Table 1 human skin patch result
Human skin patch table 1 as a result shows: skin adverse reaction appears in 30 philtrums, 0 example; Illustrate that skin care compositions of the present invention is safe in utilization.
Test example 2: the evaluation of moisture-keeping efficacy
One, experimental principle
Human experimentation, the crowd forms test population by particular experiment, and test subject makes the variation of (and cosmetic industry composition) front and back moisture of skin and moisture loss that applies some make up, thereby determines the moisture-keeping efficacy of cosmetics (or functional component).
Two, experimental apparatus
Moisture content of skin test Corneometer CM825, moisture scatter and disappear through skin and test Tewameter TM300.
Three, experiment crowd and testing time
The experimenter amounts to 30 people.Concrete sex composition and age structure are determined at random.
Four, experimental technique
1. select the left and right cheek of experimenter cycle labeling successively: be subjected to examination zone and blank zone;
2. use moisture content of skin test Corneometer CM825, moisture to scatter and disappear by the technical staff and test the TewameterTM300 measurement, average, be designated as blank value through skin.
3. tried the zone at experimenter's cheek and smear moisturiser sample (with test example 1), blank sample (with test example 1) is smeared in the blank zone; At experimental session, the experimenter does not use other any cosmetics.
The experimenter make continuously applied some make up one hour, two hours, four hours after, use moisture content of skin test Corneometer CM825, moisture to measure 5 times by the technical staff through the skin test Tewameter TM300 that scatters and disappears, average.
5. the statistics experimenter tests the numerical value that the position records at every turn, analyzes its moisture of skin and moisture loss Changing Pattern.
Five, experimental result
The result as Figure 1-3, wherein Fig. 1-3 is respectively skin hydration rate, skin moisture content and the skin rate change curve in time of preserving moisture relatively; As can be seen from the figure, the moisturiser sample had the lock of continuing water effect in four hours, preserve moisture significantly.
Test example 3: clinical experiment
Be divided into 2 groups with the experimenter of test in the example 2 is parallel, first group leader's phase (3 months) was used moisturiser sample (with test example 1); Second group is used blank sample (with test example 1); Using method identical (each once is applied in face sooner or later) at experimental session, except basic cleaning skin protection, is no longer carried out other skin protection work.After 3 months, at first outward appearance is observed first group of experimenter, finds that this group experimenter's the general water of face skin is tender glossy, strokes also smoother softness; Relatively, second group of experimenter's face skin is coarse relatively unsmooth, and complexion is darker.Secondly the moisture content of skin of test subject finds that second group of experimenter's of face skin water content average specific of first group of experimenter face skin water content exceeds 8-10%.
Can prove that by above-mentioned test the application's preserving moisture and protecting skin compositions has permanent moistening effect.
Above-described embodiment is described preferred implementation of the present invention; be not that scope of the present invention is limited; design under the prerequisite of spirit not breaking away from the present invention; various distortion and improvement that the common engineers and technicians in this area make technical scheme of the present invention all should fall in the definite protection domain of claims of the present invention.
Claims (8)
1. the skin care compositions with moisture-keeping efficacy is characterized in that, crude drug is: count by weight,
The Radix Astragali 10～30; Radix Salviae Miltiorrhizae 3～10; Cortex Magnoliae Officinalis 4～16; Flos Lonicerae 3～15; Radix Glycyrrhizae 2～10; Radix Saposhnikoviae 3～12.
2. skin care compositions according to claim 1 is characterized in that, crude drug is: count by weight,
The Radix Astragali 20; Radix Salviae Miltiorrhizae 5; Cortex Magnoliae Officinalis 6; Flos Lonicerae 6; Radix Glycyrrhizae 5; Radix Saposhnikoviae 6.
3. claim 1 or 2 described skin care compositionss have application in the skin care item of moisture-keeping efficacy in preparation.
4. application according to claim 3 is characterized in that, described skin care item are moisturiser, moisture-retention gel, moisturizing emulsion, moisture retention water and/or hand cream.
5. application according to claim 3 is characterized in that described skin care item also comprise glycerol and/or antiseptic.
6. the preparation method of claim 1 or 2 described skin care compositionss is characterized in that, step is:
(1) takes by weighing each crude drug respectively according to consumption;
(2) Radix Astragali and Radix Glycyrrhizae are mixed, and Yu Shuizhong soaked 0.5～2 hour, the mass volume ratios of described two flavor crude drug total amounts and water are (0.5～1): (10～30) g/ml, be heated to 80～100 ℃, and be incubated 0.5～2 hour;
(3) Radix Salviae Miltiorrhizae, Cortex Magnoliae Officinalis, Flos Lonicerae and Radix Saposhnikoviae are mixed, and Yu Shuizhong soaked 2～4 hours, the mass volume ratios of described four flavor crude drug total amounts and water are (0.5～1): (15～40) g/ml, be heated to 100 ℃, and be incubated 30 minutes～1 hour;
(4) extracting solution that described step (2) and (3) are obtained carries out coarse filtration respectively, and filtrate is merged;
(5) filtrate that step (4) is obtained is cooled to 30～50 ℃, carries out vacuum filtration, gets filtrate, obtains activity extract.
7. preparation method according to claim 6 is characterized in that, coarse filtration is to filter with 200～300 order gauzes in the described step (4).
8. according to claim 6 or 7 described preparation methoies, it is characterized in that vacuum filtration is to use plate-and-frame filtration in the described step (5), vacuum is 0.05～0.1Mpa, and the filter plate fineness is 1～5 micron.
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| CN105194285A (en) * | 2015-05-28 | 2015-12-30 | 孟宏 | Radiation-proof external traditional Chinese medicine composition and cream with skin barrier repair effect and preparation method thereof |
| CN106333896A (en) * | 2016-10-08 | 2017-01-18 | 广州丹奇日用化工厂有限公司 | Cosmetic composition containing oligopeptide-1 and application thereof |
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| CN104784075A (en) * | 2015-04-01 | 2015-07-22 | 广西大学 | Herbal mask powder capable of effectively moisturizing |
| CN105194285A (en) * | 2015-05-28 | 2015-12-30 | 孟宏 | Radiation-proof external traditional Chinese medicine composition and cream with skin barrier repair effect and preparation method thereof |
| CN105194285B (en) * | 2015-05-28 | 2019-02-05 | 孟宏 | Have effects that radiation protection and repair the external medicine composition of skin barrier, cream and preparation method thereof |
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| CN102274153B (en) | 2012-11-21 |
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