CN102271632A - 可原位再填充的眼植入物 - Google Patents

可原位再填充的眼植入物 Download PDF

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Publication number
CN102271632A
CN102271632A CN2009801534855A CN200980153485A CN102271632A CN 102271632 A CN102271632 A CN 102271632A CN 2009801534855 A CN2009801534855 A CN 2009801534855A CN 200980153485 A CN200980153485 A CN 200980153485A CN 102271632 A CN102271632 A CN 102271632A
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CN
China
Prior art keywords
implant
eyes
mentioned
opening
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801534855A
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English (en)
Chinese (zh)
Inventor
A·L·韦纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Research LLC
Original Assignee
Alcon Research LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Research LLC filed Critical Alcon Research LLC
Publication of CN102271632A publication Critical patent/CN102271632A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
CN2009801534855A 2009-01-02 2009-12-18 可原位再填充的眼植入物 Pending CN102271632A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14224209P 2009-01-02 2009-01-02
US61/142,242 2009-01-02
PCT/US2009/068613 WO2010078063A1 (en) 2009-01-02 2009-12-18 In-situ refillable ophthalmic implant

Publications (1)

Publication Number Publication Date
CN102271632A true CN102271632A (zh) 2011-12-07

Family

ID=42077107

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801534855A Pending CN102271632A (zh) 2009-01-02 2009-12-18 可原位再填充的眼植入物

Country Status (13)

Country Link
US (1) US20100174272A1 (enExample)
EP (1) EP2379027A1 (enExample)
JP (1) JP2012514493A (enExample)
KR (1) KR20110119681A (enExample)
CN (1) CN102271632A (enExample)
AR (1) AR076637A1 (enExample)
AU (1) AU2009333100B2 (enExample)
BR (1) BRPI0923810A2 (enExample)
CA (1) CA2750178A1 (enExample)
MX (1) MX2011006726A (enExample)
TW (1) TW201026300A (enExample)
WO (1) WO2010078063A1 (enExample)
ZA (1) ZA201104271B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908226A (zh) * 2012-11-12 2013-02-06 杨勋 稳固型自疏通青光眼钉
CN105246438A (zh) * 2013-03-28 2016-01-13 弗赛特影像4股份有限公司 用于输送治疗物质的眼科植入物
CN109195556A (zh) * 2016-04-05 2019-01-11 弗赛特影像4股份有限公司 可植入眼睛药物递送装置
CN109431678A (zh) * 2018-12-17 2019-03-08 中国医学科学院北京协和医院 经巩膜角膜药物传输系统
CN113230019A (zh) * 2021-04-16 2021-08-10 南京佑羲医药科技有限公司 一种用于眼球玻璃体内植入的长效缓释给药装置
WO2025172440A1 (en) 2024-02-16 2025-08-21 F. Hoffmann-La Roche Ag Port device for introducing a liquid pharmaceutical compound into an intraocular space

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2683224C (en) 2001-04-07 2014-12-02 Glaukos Corporation System and methods thereof for treatment of ocular disorders
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
EP2316394B1 (en) 2001-06-12 2016-11-23 The Johns Hopkins University Reservoir device for intraocular drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
SG173167A1 (en) 2009-01-29 2011-08-29 Forsight Labs Llc Posterior segment drug delivery
WO2010093945A2 (en) 2009-02-13 2010-08-19 Glaukos Corporation Uveoscleral drug delivery implant and methods for implanting the same
WO2012071476A2 (en) 2010-11-24 2012-05-31 David Haffner Drug eluting ocular implant
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
EP4289416A3 (en) * 2009-05-18 2024-01-03 Dose Medical Corporation Drug eluting ocular implant
US10206813B2 (en) * 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US8419673B2 (en) 2009-09-21 2013-04-16 Alcon Research, Ltd. Glaucoma drainage device with pump
US8545431B2 (en) * 2009-09-21 2013-10-01 Alcon Research, Ltd. Lumen clearing valve for glaucoma drainage device
US8257295B2 (en) 2009-09-21 2012-09-04 Alcon Research, Ltd. Intraocular pressure sensor with external pressure compensation
US8721580B2 (en) * 2009-09-21 2014-05-13 Alcon Research, Ltd. Power saving glaucoma drainage device
CA2807508A1 (en) * 2010-08-05 2012-02-09 Forsight Vision4, Inc. Subconjunctival implant for posterior segment drug delivery
EP2600812B1 (en) * 2010-08-05 2021-09-22 ForSight Vision4, Inc. Apparatus to treat an eye
HUE054113T2 (hu) 2010-08-05 2021-08-30 Forsight Vision4 Inc Injekciós készülék gyógyszerbejuttatáshoz
WO2012019139A1 (en) 2010-08-05 2012-02-09 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
US9605663B2 (en) * 2010-08-24 2017-03-28 Qwtip Llc System and method for separating fluids and creating magnetic fields
US8235053B2 (en) 2010-09-08 2012-08-07 Alcon Research, Ltd. Implantable punctal plug
US8864703B2 (en) 2010-10-05 2014-10-21 Alcon Research, Ltd. Drug introduction and placement system
WO2012068549A2 (en) 2010-11-19 2012-05-24 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
WO2013003620A2 (en) 2011-06-28 2013-01-03 Forsight Vision4, Inc. Diagnostic methods and apparatus
US10307292B2 (en) 2011-07-18 2019-06-04 Mor Research Applications Ltd Device for adjusting the intraocular pressure
EP2739252A4 (en) * 2011-08-05 2015-08-12 Forsight Vision4 Inc SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE
WO2013040247A2 (en) 2011-09-16 2013-03-21 Forsight Vision4, Inc. Fluid exchange apparatus and methods
US8585631B2 (en) 2011-10-18 2013-11-19 Alcon Research, Ltd. Active bimodal valve system for real-time IOP control
US8840578B2 (en) 2011-12-09 2014-09-23 Alcon Research, Ltd. Multilayer membrane actuators
US8579848B2 (en) 2011-12-09 2013-11-12 Alcon Research, Ltd. Active drainage systems with pressure-driven valves and electronically-driven pump
WO2013090197A1 (en) 2011-12-12 2013-06-20 Alcon Research, Ltd. Active drainage systems with dual-input pressure-driven valves
WO2013090231A1 (en) 2011-12-13 2013-06-20 Alcon Research, Ltd. Active drainage systems with dual-input pressure-driven valves
US9339187B2 (en) 2011-12-15 2016-05-17 Alcon Research, Ltd. External pressure measurement system and method for an intraocular implant
WO2013116061A1 (en) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
WO2013148275A2 (en) 2012-03-26 2013-10-03 Glaukos Corporation System and method for delivering multiple ocular implants
US9528633B2 (en) 2012-12-17 2016-12-27 Novartis Ag MEMS check valve
US9572712B2 (en) 2012-12-17 2017-02-21 Novartis Ag Osmotically actuated fluidic valve
US9295389B2 (en) 2012-12-17 2016-03-29 Novartis Ag Systems and methods for priming an intraocular pressure sensor in an intraocular implant
US9968603B2 (en) 2013-03-14 2018-05-15 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
US9597227B2 (en) * 2013-03-15 2017-03-21 Abbott Medical Optics Inc. Trans-sclera portal for delivery of therapeutic agents
US10093978B2 (en) 2013-08-12 2018-10-09 Genentech, Inc. Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms
US9226851B2 (en) 2013-08-24 2016-01-05 Novartis Ag MEMS check valve chip and methods
US9283115B2 (en) 2013-08-26 2016-03-15 Novartis Ag Passive to active staged drainage device
US9289324B2 (en) 2013-08-26 2016-03-22 Novartis Ag Externally adjustable passive drainage device
US9681983B2 (en) 2014-03-13 2017-06-20 Novartis Ag Debris clearance system for an ocular implant
US9603742B2 (en) 2014-03-13 2017-03-28 Novartis Ag Remote magnetic driven flow system
EA201692109A1 (ru) 2014-05-01 2017-03-31 Дженентек, Инк. Варианты антител к фактору d и их применение
EP3677229A1 (en) 2014-05-29 2020-07-08 Glaukos Corporation Implants with controlled drug delivery features
EP3169289B1 (en) 2014-07-15 2020-04-15 ForSight Vision4, Inc. Ocular implant delivery device
MY182793A (en) 2014-08-08 2021-02-05 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
AU2015346450B2 (en) 2014-11-10 2020-01-30 Forsight Vision4, Inc. Expandable drug delivery devices and method of use
WO2016164406A1 (en) * 2015-04-06 2016-10-13 The Regents Of The University Of Colorado, A Body Corporate Intraocular oxygen delivery and absorption devices and methods
US9655777B2 (en) 2015-04-07 2017-05-23 Novartis Ag System and method for diagphragm pumping using heating element
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
WO2017075252A1 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibody variant conjugates and uses thereof
US10407510B2 (en) 2015-10-30 2019-09-10 Genentech, Inc. Anti-factor D antibodies and conjugates
JP6912475B2 (ja) 2015-11-20 2021-08-04 フォーサイト・ビジョン フォー・インコーポレーテッドForsight Vision4, Inc. 持続放出性薬物送達機器用の多孔質構造体
KR101750651B1 (ko) * 2016-01-28 2017-06-23 동국대학교 산학협력단 약물 잔류 방지능 및 재충전 기능을 갖는 안구 내 약물 주입 장치
CN115120405A (zh) 2016-04-20 2022-09-30 多斯医学公司 生物可吸收眼部药物的递送装置
EP3691586A2 (en) 2017-10-06 2020-08-12 Glaukos Corporation Systems and methods for delivering multiple ocular implants
USD846738S1 (en) 2017-10-27 2019-04-23 Glaukos Corporation Implant delivery apparatus
EP3713528A1 (en) 2017-11-21 2020-09-30 ForSight Vision4, Inc. Fluid exchange apparatus for expandable port delivery system and methods of use
PE20230414A1 (es) 2020-03-24 2023-03-07 Genentech Inc Agentes de fijacion a tie2 y metodos de uso
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
SE2351151A1 (en) * 2023-10-06 2025-04-07 Anna Herland Medical device

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3788327A (en) * 1971-03-30 1974-01-29 H Donowitz Surgical implant device
US4193397A (en) * 1977-12-01 1980-03-18 Metal Bellows Corporation Infusion apparatus and method
US4886488A (en) * 1987-08-06 1989-12-12 White Thomas C Glaucoma drainage the lacrimal system and method
US5122128A (en) * 1990-03-15 1992-06-16 Alza Corporation Orifice insert for a ruminal bolus
US5707643A (en) * 1993-02-26 1998-01-13 Santen Pharmaceutical Co., Ltd. Biodegradable scleral plug
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US20050119737A1 (en) * 2000-01-12 2005-06-02 Bene Eric A. Ocular implant and methods for making and using same
US7708711B2 (en) * 2000-04-14 2010-05-04 Glaukos Corporation Ocular implant with therapeutic agents and methods thereof
DE60135352D1 (de) 2000-08-30 2008-09-25 Univ Johns Hopkins Vorrichtung zur intraokularen wirkstoffverabreichung
CA2432438C (en) * 2001-01-09 2011-04-26 Microchips, Inc. Flexible microchip devices for ophthalmic and other applications
US6881198B2 (en) * 2001-01-09 2005-04-19 J. David Brown Glaucoma treatment device and method
EP2316394B1 (en) * 2001-06-12 2016-11-23 The Johns Hopkins University Reservoir device for intraocular drug delivery
JP2006516618A (ja) * 2003-01-24 2006-07-06 コントロール・デリバリー・システムズ・インコーポレイテッド アドレナリン作動薬を眼へ輸送するために徐放性デバイス及び方法
US20070077270A1 (en) * 2005-03-28 2007-04-05 Clemson University Delivery devices and methods for long-term, targeted delivery of therapeutic agents to the eye and ear
US20080147021A1 (en) * 2006-12-15 2008-06-19 Jani Dharmendra M Drug delivery devices

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908226A (zh) * 2012-11-12 2013-02-06 杨勋 稳固型自疏通青光眼钉
CN102908226B (zh) * 2012-11-12 2014-07-09 杨勋 稳固型自疏通青光眼钉
CN105246438A (zh) * 2013-03-28 2016-01-13 弗赛特影像4股份有限公司 用于输送治疗物质的眼科植入物
CN109195556A (zh) * 2016-04-05 2019-01-11 弗赛特影像4股份有限公司 可植入眼睛药物递送装置
CN113017981A (zh) * 2016-04-05 2021-06-25 弗赛特影像4股份有限公司 药物递送装置
CN109431678A (zh) * 2018-12-17 2019-03-08 中国医学科学院北京协和医院 经巩膜角膜药物传输系统
CN113230019A (zh) * 2021-04-16 2021-08-10 南京佑羲医药科技有限公司 一种用于眼球玻璃体内植入的长效缓释给药装置
WO2025172440A1 (en) 2024-02-16 2025-08-21 F. Hoffmann-La Roche Ag Port device for introducing a liquid pharmaceutical compound into an intraocular space

Also Published As

Publication number Publication date
AR076637A1 (es) 2011-06-29
BRPI0923810A2 (pt) 2015-07-14
MX2011006726A (es) 2011-07-20
AU2009333100B2 (en) 2014-08-14
EP2379027A1 (en) 2011-10-26
TW201026300A (en) 2010-07-16
JP2012514493A (ja) 2012-06-28
CA2750178A1 (en) 2010-07-08
WO2010078063A1 (en) 2010-07-08
AU2009333100A1 (en) 2011-07-07
KR20110119681A (ko) 2011-11-02
US20100174272A1 (en) 2010-07-08
ZA201104271B (en) 2012-08-29

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Application publication date: 20111207