CN102266416A - Alcohol-based spraying agent for burn and scald wound treatment - Google Patents
Alcohol-based spraying agent for burn and scald wound treatment Download PDFInfo
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- CN102266416A CN102266416A CN 201110177796 CN201110177796A CN102266416A CN 102266416 A CN102266416 A CN 102266416A CN 201110177796 CN201110177796 CN 201110177796 CN 201110177796 A CN201110177796 A CN 201110177796A CN 102266416 A CN102266416 A CN 102266416A
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Abstract
The invention provides an alcohol-based spraying agent for burn and scald wound treatment, and the alcohol-based spraying agent is prepared from the following raw drug ingredients in parts by weight: 450-600 parts of elm bark, 150-300 parts of phellodendron, 150-300 parts of rhubarb, 150-300 parts of rhizoma coptidis, 50-150 parts of borneol and 800-1200 parts of alcohol. In order to achieve the effects of clearing away heat and relieving pain, resisting against bacteria and diminishing swelling, cooling blood and eliminating stasis, the combination of elm bark, phellodendron, rhubarb, rhizoma coptidis, borneol and alcohol is adopted, so that the synergic effect of the drug ingredients is generated, thus the spraying agent can be effectively used for emergency treatment of burn and scald wound.
Description
Technical field
The present invention relates to external medicinal herb spray field, be specifically related to a kind of wine base spray that is used for the empyrosis wound surface emergency processing, pain relieving at once, prevent that the deterioration of wound surface from infecting, for I degree burn, scald and have the effect of rapid treatment.
Background technology
After burn, the scald, a lot of people smear gentian voiet, mercurochrome, Gentian Violet etc. on wound, and these are harmful on the contrary to wound.The medicine that scribbles color at empyrosis wound surface can influence the judgement of doctor to depth of burn, and the judgement of depth of burn is that the doctor works out one of treatment plan very important basis.Moreover, among the people have many be used to burn or scald after wound surface " indigenous method " handled, be coated with Adeps melis outward such as wound surface, plant ash, or even some Chinese medicine preparation.From the angle of modern medicine, these processing methods among the people tend to cause traumatic infection, increase the weight of the wound surface damage, thereby are worthless.Correctly smearing medicine has: safflower oil, vaseline, moist expose burn ointment etc. can effectively reduce wound pain, and the effect of certain protection wound surface is also arranged.The common recognition of medical circle is at present: only just can help host's phagocyte in moistening condition and play a role, promote that inflammation disappears, protect from infection.Simultaneously moist environment also can prevent exposing of teleneuron and death, alleviates wound pain, helps the dissolving of slough and promotes the release of multiple somatomedin, provides an ideal environment to wound healing, thus the promotion wound healing.
The number of the applying for a patent CN200510038222.3 of Wang Laiyi discloses " medicine of a kind of burn and scald early time treatment and preparation method thereof; it is a crude drug with Radix Scutellariae, Fructus Gardeniae, Rhizoma Chuanxiong, the Radix Astragali, Radix Angelicae Sinensis, Radix Notoginseng, Radix Paeoniae Rubra, Pericarpium Zanthoxyli, Natrii Sulfas, Rhizoma Zingiberis Recens, Borneolum Syntheticum mainly; be prepared into liquor according to a certain weight ratio; be coated with usefulness behind the burn immediately on wound surface; pain relieving at once; the red and swollen disappearance, the may command blister forms.”
Summary of the invention
The object of the present invention is to provide a kind of empyrosis wound surface to handle the wine base spray with effect of antipyretic analgesic, antibacterial detumescence, cooling blood and dissolving stasis, be used for burn, scald wound processing, at once pain relieving, prevent that the deterioration of wound surface from infecting, for I degree burn, scald and have the effect of rapid treatment.
Technical scheme of the present invention:
Empyrosis wound surface of the present invention is handled the raw medicinal material of wine base spray and the consumption of composition by weight is groped to sum up to draw through the inventor in a large number, and the each component consumption all has effect preferably in this scope: Cortex ulmi pumilae 450-600 part, Cortex Phellodendri 150-300 part, Radix Et Rhizoma Rhei 150-300 part, Rhizoma Coptidis 150-300 part, Borneolum Syntheticum 50-150 part, ethanol 800-1200 part.
Be preferably: 500 parts of Cortex ulmi pumilae, 200 parts of Cortex Phellodendris, 200 parts of Radix Et Rhizoma Rhei, 200 parts of Rhizoma Coptidis, 100 parts of Borneolum Syntheticums, 1000 parts of ethanol.
Preparation method: step 1, the Cortex ulmi pumilae with described weight portion, Cortex Phellodendri, Radix Et Rhizoma Rhei, Rhizoma Coptidis powder are broken into asperities, and the gauze outsourcing is immersed in the ethanol and steeped seven days, takes on a red color, and filter and remove residue adds Borneolum Syntheticum; Step 2, medicinal liquid that step 1 obtains is sub-packed in the little spray bottle gets final product.
Using method: cut off blister earlier, use the lignocaine localized pulverization earlier before the medication first, spray this medicine again, about one day four times.
Indication: burn, burn, scald
Use taboo:
1, children's and facial careful usefulness it should be noted that when using lignocaine local anaesthetics thing allergy sufferers are forbidden.
2, lignocaine sprays and can reduce pain.
3, after this medicine even sprays three times, can form protecting film (incrustation) in the wound surface appearance, protecting film (crust sheet) will come off voluntarily, must not go crust, in order to avoid stay scar.
For reaching the effect of antipyretic analgesic, antibacterial detumescence, cooling blood and dissolving stasis, the present invention selects: Cortex ulmi pumilae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Rhizoma Coptidis, Borneolum Syntheticum make up, with these drug regimens, make each efficacy of drugs produce synergism, thereby can be effective to burn, scald the emergency processing of hindering wound surface.In the raw materials of traditional Chinese medicinal materials that the present invention chooses, its effect and pharmacological action are respectively:
Cortex ulmi pumilae: [source] this product is dry bark or the root bark of Ulmaceae plant elm Ulmus pumila L..[processing of gathering] winter, spring gather, and take advantage of to scrape off the taupe brown cork when fresh, vertically cut open, touch with mallet, and skin is separated with core, strip Rhizoma Euonymus, dry.[nature and flavor and function] is sweet, flat.Nontoxic.Diuretic, treating stranguria, detumescence.Be used for urinary obstruction, stranguria with turbid discharge, edema, carbuncle carbuncle on the back, erysipelas, scabies.
Cortex Phellodendri [meridian distribution of property and flavor] hardship, cold.Return kidney, bladder, large intestine channel.[function with cure mainly] heat clearing and damp drying, eliminating fire and detoxication removes the hectic fever due to YIN-deficiency clearind deficient heat.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency.[chemical constituent] Cortex Phellodendri mainly contains berberine about 1.6%, still contain palmatine, phellodendrine, jateorhizine, obacunone, Caulis menispermi is appointed alkali, candicine, magnoline, limonin etc. root bark is isolated berberine about 9%, still contain jateorhizine, phellodendrine, candicine. the Cortex Phellodendri content of berberine is higher, reaching the 3%.[antibacterial action] the Cortex Phellodendri antibiotic effective ingredient is berberine. Cortex Phellodendri decoct or pure preserved material in vitro tests are to staphylococcus aureus, Staphylococcus albus, Staphylococcus citreus, Diplococcus pneumoniae, meningococcus, Streptococcus viridans, vibrio cholera, diphtheria corynebacterium, dysentery bacterium, bacillus pyocyaneus etc. all have inhibitory action, to escherichia coli, the Bacillus typhi nearly unavailable. report is also arranged for the escherichia coli responder. with regard to crude drug, Antibacterial Function of Coptis is strong 1 times than Cortex Phellodendri. and the in vitro tests Cortex Phellodendri also has inhibitory action to tubercule bacillus, and to anti-streptomycin, aminosalicylic acid, the mycobacterium tuberculosis strain of isoniazid is also effective. when doing the experiment treatment with Cavia porcellus inoculation mycobacterium hominis, curative effect oral or injection is all very poor. to the Cavia porcellus of inoculation Mycobacterium bovis, do intramuscular injection from the hydrochloric acid crystal that Cortex Phellodendri is extracted, certain curative effect is arranged.Cortex Phellodendri is taken a favorable turn to the clinical symptoms and the X ray examination of tuberculosis patient, and is better than Rhizoma Coptidis.
Radix Et Rhizoma Rhei: [another name]: Radix Et Rhizoma Rhei, general, yellow good, fire ginseng, skin as, another name for Sichuan Province Radix Et Rhizoma Rhei, Radixet Rhizoma Rhei, cow tongue Radix Et Rhizoma Rhei, bright and beautiful stricture of vagina, give birth to army.[meridian distribution of property and flavor] hardship, cold.Gui Jing: stomach warp; Large intestine channel; Liver Channel; Spleen channel.[function cures mainly]: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Detoxifcation; The excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; The edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stasis of blood stagnated and suffered from abdominal pain puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.[medical material Ji Yuan]: be the root and the rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.[chemical constituent] Radix Et Rhizoma Rhei contains anthracene derivative, stilbenes compound, tannin class, organic acid, volatile oil etc.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire.[anastalsis]: characteristics: effect is definite, instant effect.[hemostasis effective ingredient]: α-catechin, gallic acid.[anastalsis mechanism]: promote hematoblastic adhesion and aggregation capability; Platelet increasing number and fibrinogen content; Reduce the antithrombin activity; Make injured partial vasoconstriction.[anti-infectious function] antimicrobial spectrum: responsive antibacterial has staphylococcus, Hemolytic streptococcus, micrococcus gonococcus, diphtheria corynebacterium, Bacillus typhi, dysentery bacterium etc.Responsive virus has influenza virus, Orphan virus, hepatitis B virus, poliovirus etc.Other sensitive microbials have ameba, trichomonas vaginitis, schistosomicide and leptospira etc.[antibiotic effective ingredient]: chrysophanic acid, emodin, aloe-emodin.Antibacterial action mechanism: the enzyme system that influences folic acid; Suppress bacterial nucleic acid and protein synthesis; Suppress the bacterium living beings oxidase system; Inducement interferon.(2) antiinflammatory, refrigeration function.(3) immunomodulating: anthraquinone derivative can suppress non-specific immunity.(4) defying age antioxidation, more and more both at home and abroad scholars prove that the contained tannin of Radix Et Rhizoma Rhei has good antioxidation.
Rhizoma Coptidis [nature and flavor] hardship, cold, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated.[chemical analysis] rhizome contains multiple isoquinoline alkaloid, and is the highest with content of berberine, is 5～8%, still contains coptisine, 13-methyl-.psi.-coptisine., palmatine, jateorhizine, epiberberine and magnoflorine etc.; Acid ingredient has ferulic acid, chlorogenic acid etc.Fibrous root contains berberine can reach 5%; Leaf of Rhizoma Coptidis contains berberine 1.4%～2.9%.[mechanism of action] 1. stops the K+ outflow.2. increase Ca2+ concentration in the cell.3. suppress the generation of free radical, reduce the damage of lipid peroxide myocardial cell.4. reduce myocardial oxygen consumption.[Detoxication] antagonism bacteriotoxin, reduction staphylococcus aureus coagulase, hemolysin are tired, and reduce colibacillary virulence.[antiinflammatory, analgesic] 1. suppresses the kinds of experiments inflammation, and effective ingredient is a berberine, and antiinflammatory mechanism discharges relevant with the stimulation corticotropin; 2. refrigeration function is relevant with the neuronic generation in PO/AH district of inhibition maincenter.
Borneolum Syntheticum: other titles: Borneolum Syntheticum, Borneolum Syntheticum, brain, Borneolum Syntheticum, sheet brain, Borneolum Syntheticum brain, Flos Mume brain, natural Broneolum Syntheticum, old borneol, borneol.[main component]: this product is the crystallization that obtains from the resin of Borneolum Syntheticum and volatile oil, is to be close to pure dextro Borneolum Syntheticum.Contain multiple ter penoids in the resin of Borneolum Syntheticum and the volatile oil.Except that Borneolum Syntheticum, still contain sesquiterpenes such as Humuleno, beta-elemene, caryophyllene, triterpenoids such as oleanolic acid, alphitolic acid, asiatic acid, dipterocarpol, dryobalanone, erythrodiol.[function with cure mainly] logical all keys, the stagnated fire of loosing, removing nebula makes eye bright, reducing swelling and alleviating pain.Control the apoplexy locked mouth, the calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is the nebula film also, enterobiasis.[pharmacological action]: antibacterial, antiinflammatory action experiment in vitro shows: the Borneolum Syntheticum of higher concentration (0.5%) has bacteriostasis.The bacteriostasis of synthetic borneol and natural Broneolum Syntheticum is identical.Borneolum Syntheticum, isoborneol all have antibacterial action; And all can significantly suppress rat Ovum Gallus domesticus album pedal swelling; Isoborneol also has inhibitory action to the Oleum Tiglii auricle edema.Point out them that oozing out with the swollen process of inflammation such as tissue edema of liquid had inhibitory action.Above reference material " Baidu's encyclopaedia ".
Be the Da Gengjia result of use, the present invention also provides this empyrosis wound surface to handle spray preparing process; Preparation method: step 1, the Cortex ulmi pumilae with described weight portion, Cortex Phellodendri, Radix Et Rhizoma Rhei, Rhizoma Coptidis powder are broken into asperities, and the gauze outsourcing is immersed in the ethanol and steeped seven days, takes on a red color, and filter and remove residue adds Borneolum Syntheticum; Step 2, medicinal liquid that step 1 obtains is sub-packed in the little spray bottle gets final product.
Empyrosis wound surface of the present invention is handled spray, effect with antipyretic analgesic, antibacterial detumescence, cooling blood and dissolving stasis, be used to burn, scald the emergency processing of hindering wound surface, pain relieving at once, prevent that the deterioration of wound surface from infecting, for I degree burn, scald and have the effect of rapid treatment.
So far, still not finding the report and the application of relevant Chinese medicine empyrosis wound surface processing wine base spray of the present invention, particularly is the wine base spray that main component and described other raw medicinal material compatibilities are made with the Cortex ulmi pumilae.The inventor is through research repeatedly, and the checking repeatedly by clinical trial, and having found finally has the external of better curative effect Chinese medicine empyrosis wound surface processing wine base spray, thereby has finished the present invention.
Basic document:
Utilize empyrosis wound surface of the present invention to handle the wine base spray, clinically be used for I in Dengfeng City, Henan Province institute of traditional Chinese medicine, II degree empyrosis wound surface is handled; 2009--2011 empyrosis wound surface in February is handled 359 examples; Therapeutic Method: directly spray the affected part; Blister is arranged, cut off blister and again spray is sprayed the affected part.Effect: pain relieving at once, the cool and comfortable sense is arranged, colourless trace is convenient to the condition of the injury and is judged, does not have to worsen and infects.
Specific implementation method
Embodiment one; Empyrosis wound surface of the present invention is handled the wine base spray, and its raw medicinal material and components by weight percent are respectively; Cortex ulmi pumilae 450-600 part, Cortex Phellodendri 150-300 part, Radix Et Rhizoma Rhei 150-300 part, Rhizoma Coptidis 150-300 part, Borneolum Syntheticum 50-150 part, ethanol 800-1200 part.
Be preferably: 500 parts of Cortex ulmi pumilae, 200 parts of Cortex Phellodendris, 200 parts of Radix Et Rhizoma Rhei, 200 parts of Rhizoma Coptidis, 100 parts of Borneolum Syntheticums, 1000 parts of ethanol.
Preparation method: step 1, the Cortex ulmi pumilae with described weight portion, Cortex Phellodendri, Radix Et Rhizoma Rhei, Rhizoma Coptidis powder are broken into asperities, and the gauze outsourcing is immersed in the ethanol and steeped seven days, takes on a red color, and filter and remove residue adds Borneolum Syntheticum; Step 2, medicinal liquid that step 1 obtains is sub-packed in the little spray bottle gets final product.
Claims (2)
1. an empyrosis wound surface is handled the wine base spray, and it is characterized in that: its raw medicinal material and components by weight percent are respectively; Cortex ulmi pumilae 450-600 part, Cortex Phellodendri 150-300 part, Radix Et Rhizoma Rhei 150-300 part, Rhizoma Coptidis 150-300 part, Borneolum Syntheticum 50-150 part, ethanol 800-1200 part.
2. handle the wine base spray according to the described a kind of empyrosis wound surface of claim 1, it is characterized in that: preparation method: step 1, the Cortex ulmi pumilae with described weight portion, Cortex Phellodendri, Radix Et Rhizoma Rhei, Rhizoma Coptidis powder are broken into asperities, the gauze outsourcing, immerse in the ethanol and steeped seven days, take on a red color, filter and remove residue adds Borneolum Syntheticum; Step 2, medicinal liquid that step 1 obtains is sub-packed in the little spray bottle gets final product.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716357A (en) * | 2012-06-18 | 2012-10-10 | 梁小松 | Medicament for treating scald without scar left and preparation method of medicament |
| CN105267377A (en) * | 2014-06-26 | 2016-01-27 | 杨秀凯 | Miao ethnomedicine medicated wine for treating burns and scalds |
| CN109364145A (en) * | 2018-12-29 | 2019-02-22 | 王德荣 | A kind of Chinese medicine burn spray and preparation method |
| CN110038059A (en) * | 2019-03-15 | 2019-07-23 | 广州中医药大学第一附属医院 | One kind three lowigite ice burn Chinese medicine oil and preparation method thereof |
-
2011
- 2011-06-29 CN CN 201110177796 patent/CN102266416A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 《开卷有益求医问药》 19950331 刘国应 中医治疗烧烫伤新方(下) 26 1 , 第3期 * |
| 《辽宁中医学院学报》 20031130 韦东 中医药治疗烧伤的研究及其进展 388 1 第5卷, 第4期 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716357A (en) * | 2012-06-18 | 2012-10-10 | 梁小松 | Medicament for treating scald without scar left and preparation method of medicament |
| CN105267377A (en) * | 2014-06-26 | 2016-01-27 | 杨秀凯 | Miao ethnomedicine medicated wine for treating burns and scalds |
| CN109364145A (en) * | 2018-12-29 | 2019-02-22 | 王德荣 | A kind of Chinese medicine burn spray and preparation method |
| CN109364145B (en) * | 2018-12-29 | 2021-09-14 | 王德荣 | Traditional Chinese medicine spray for treating burn and preparation method thereof |
| CN110038059A (en) * | 2019-03-15 | 2019-07-23 | 广州中医药大学第一附属医院 | One kind three lowigite ice burn Chinese medicine oil and preparation method thereof |
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Application publication date: 20111207 |