CN102245172B - 包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法 - Google Patents

包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法 Download PDF

Info

Publication number
CN102245172B
CN102245172B CN2009801504351A CN200980150435A CN102245172B CN 102245172 B CN102245172 B CN 102245172B CN 2009801504351 A CN2009801504351 A CN 2009801504351A CN 200980150435 A CN200980150435 A CN 200980150435A CN 102245172 B CN102245172 B CN 102245172B
Authority
CN
China
Prior art keywords
metformin
preparation
hydroxy propyl
propyl cellulose
voglibose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2009801504351A
Other languages
English (en)
Chinese (zh)
Other versions
CN102245172A (zh
Inventor
赵日焕
洪一基
安泰军
李镕宅
郑善五
尹明植
权五亿
李恃氾
吴多苑
崔洛铉
李熙贞
卢贤贞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CJ Medical and Health Co., Ltd.
Original Assignee
CJ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CJ Corp filed Critical CJ Corp
Publication of CN102245172A publication Critical patent/CN102245172A/zh
Application granted granted Critical
Publication of CN102245172B publication Critical patent/CN102245172B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2009801504351A 2008-12-15 2009-12-10 包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法 Expired - Fee Related CN102245172B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2008-0127289 2008-12-15
KR1020080127289A KR101189639B1 (ko) 2008-12-15 2008-12-15 메트포르민 및 α-글리코시다제 억제제를 포함하는 경구 제제 및 그 제조방법
PCT/KR2009/007383 WO2010071321A2 (ko) 2008-12-15 2009-12-10 메트포르민 및 α-글리코시다제 억제제를 포함하는 경구 제제 및 그 제조방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2013100288368A Division CN103143018A (zh) 2008-12-15 2009-12-10 包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法

Publications (2)

Publication Number Publication Date
CN102245172A CN102245172A (zh) 2011-11-16
CN102245172B true CN102245172B (zh) 2013-04-10

Family

ID=42269214

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2013100288368A Pending CN103143018A (zh) 2008-12-15 2009-12-10 包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法
CN2009801504351A Expired - Fee Related CN102245172B (zh) 2008-12-15 2009-12-10 包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN2013100288368A Pending CN103143018A (zh) 2008-12-15 2009-12-10 包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法

Country Status (4)

Country Link
JP (2) JP5371068B2 (ko)
KR (1) KR101189639B1 (ko)
CN (2) CN103143018A (ko)
WO (1) WO2010071321A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101336499B1 (ko) * 2013-03-06 2013-12-03 씨제이제일제당 (주) 당뇨병의 예방 또는 치료용 복합 조성물
US20200164047A1 (en) * 2017-05-19 2020-05-28 Università Degli Studi Di Milano Therapy and diagnosis of disease characterized by alterations in the dna damage response
CN111374952B (zh) * 2018-12-29 2022-07-26 甘李药业江苏有限公司 阿卡波糖药物组合物及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1414862A (zh) * 1999-11-03 2003-04-30 布里斯托尔-迈尔斯斯奎布公司 抗糖尿病制剂以及方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000028989A1 (en) * 1998-11-12 2000-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
KR100705210B1 (ko) * 2004-09-23 2007-04-06 주식회사 한독약품 경구투여를 위한 당뇨병 치료용 약제학적 복합제제
MXPA05010977A (es) * 2005-10-12 2007-04-11 Abdala Leopoldo Espinosa Composiciones farmaceuticas que comprenden sustancias antidiabeticas combinadas para su uso en diabetes mellitus.
KR100812538B1 (ko) * 2006-10-23 2008-03-11 한올제약주식회사 약물 제어방출형 메트포르민-글리메피리드 복합제제

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1414862A (zh) * 1999-11-03 2003-04-30 布里斯托尔-迈尔斯斯奎布公司 抗糖尿病制剂以及方法

Also Published As

Publication number Publication date
JP5671767B2 (ja) 2015-02-18
WO2010071321A2 (ko) 2010-06-24
CN102245172A (zh) 2011-11-16
CN103143018A (zh) 2013-06-12
KR20100068811A (ko) 2010-06-24
JP2013189466A (ja) 2013-09-26
JP5371068B2 (ja) 2013-12-18
WO2010071321A3 (ko) 2010-10-21
KR101189639B1 (ko) 2012-10-12
JP2012511568A (ja) 2012-05-24

Similar Documents

Publication Publication Date Title
CA2752434C (en) Pharmaceutical composition comprising linagliptin and a sglt2 inhibitor
CN111728953B (zh) 一种托法替布或其盐的缓释制剂及其制备方法
CN103655570B (zh) 西格列汀与二甲双胍复方缓释制剂及其制备方法
CN105878204B (zh) 一种盐酸二甲双胍渗透泵控释片及其制备方法
WO2021238978A1 (zh) 含硝羟喹啉前药的药物组合物及其制备方法和应用
US20080279938A1 (en) Zaltoprofen-containing sustained release tablet and process for the preparation thereof
US9421188B2 (en) Combination product comprising phentermine and topiramate, and preparation method thereof
CN102499923B (zh) 一种药物组合物、其制备方法及用途
CN102245172B (zh) 包含二甲双胍和α-糖苷酶抑制剂的口服制剂及其制备方法
EP2945618B1 (en) Combinations of a glp1r agonist and metformin and use thereof for the treatment of type 2 diabetes and other disorders
EP2073846B1 (en) Combinations of antipsychotic drugs and tetracyclines in the treatment of psychiatric disorders
US11998535B2 (en) Methods of treatment of tuberous sclerosis complex
US20040147564A1 (en) Combinations of glimepiride and the thiazolidinedione for treatment of diabetes
EP4193991A1 (en) Obizidine fumarate enteric-coated pill, preparation method therefor and use thereof
KR20050020575A (ko) 지속성 탐스로신 정제의 제조방법 및 그에 따른 지속성탐스로신 정제
CN101168059A (zh) 一种含有双胍、磺酰脲和噻唑烷二酮的稳定的药物组合物及其制备方法
CN106806353A (zh) 艾拉莫德缓释胶囊及其制备方法
Mundada Development of Alternate Drug Delivery Systems for Drugs Used in Treatment of Chronic Diseases
OA21484A (en) Methods of treatment of tuberous sclerosis complex.
CN102349905B (zh) 一种二甲双胍晶体及其与吡格列酮的药用组合物与制备方法
KR20220101148A (ko) 암의 치료를 위한 소아용 제제
Deb Formulation Development and Optimization of Extended Release Pellets filled in Hard Gelatin Capsules Comtaining an Antimuscarinic Agent
CN101444626A (zh) 一种含有双胍、磺酰脲和噻唑烷二酮的稳定的药物组合物及其制备方法
WO2017115252A1 (en) An oral osmotic pharmaceutical composition of vildagliptin
CN104224859A (zh) 银杏叶提取物缓释微丸制剂

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: CJ CHEILJEDANG CORP.

Free format text: FORMER OWNER: CJ CORP.

Effective date: 20150129

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20150129

Address after: Seoul, South Kerean

Patentee after: CJ Medical and Health Co., Ltd.

Address before: Seoul, South Korea

Patentee before: CJ Corp.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130410

Termination date: 20181210