CN102228648A - Chinese medicinal composition for treating icterohepatitis - Google Patents
Chinese medicinal composition for treating icterohepatitis Download PDFInfo
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- CN102228648A CN102228648A CN2011101745501A CN201110174550A CN102228648A CN 102228648 A CN102228648 A CN 102228648A CN 2011101745501 A CN2011101745501 A CN 2011101745501A CN 201110174550 A CN201110174550 A CN 201110174550A CN 102228648 A CN102228648 A CN 102228648A
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Abstract
The invention relates to a Chinese medicinal composition for treating icterohepatitis, which consists of the following components by weight: 60 to 75 grams of virgate wormwood herb, 15 to 30 grams of stringy stonecrop herb, 10 to 15 grams of rhubarb, 5 to 9 grams of vinegar turtle shell, 10 to 15 grams of root of red-rooted salvia, 10 to 15 grams of astragalus, 3 to 5 grams of glabrous greenbrier rhizome, 5 to 7 grams of costustoot, 10 to 13 grams of spreading hedyotis herb, 15 to 18 grams of vinegar Chinese magnoliavine fruit, 20 to 24 grams of bupleurum and 30 to 45 grams of folium isatidis. Therefore the Chinese medicinal composition has the good effect on the treatment of the icterohepatitis.
Description
One, technical field
The present invention relates to a kind of Chinese medicine composition that is used for the treatment of icterohepatitis.
Two, background technology
Icterohepatitis is very high at China's sickness rate, though multiple medicine is arranged can treat, because the side effect of Chinese medicine composition deposits yields is less, the traditional Chinese medicine composition for treating icterohepatitis is widely used, therefore the Chinese medicine composition that is used for the treatment of icterohepatitis is a kind of important medicament, in the existing Chinese medicine composition that is used for the treatment of icterohepatitis, the effect of treatment icterohepatitis is not so good.
Three, summary of the invention
The objective of the invention is to be used for the treatment of the Chinese medicine composition of icterohepatitis, the better effects if of treatment icterohepatitis.
For achieving the above object, the technical scheme of taking of the present invention is: medicine of the present invention is formed, and is made up of Herba Artemisiae Scopariae 60-75 gram, Herba Sedi 15-30 gram, Radix Et Rhizoma Rhei 10-15 gram, Carapax Trionycis (processed with vinegar) 5-9 gram, Radix Salviae Miltiorrhizae 10-15 gram, Radix Astragali 10-15 gram, Rhizoma Smilacis Glabrae 3-5 gram, Radix Aucklandiae 5-7 gram, Herba Hedyotidis Diffusae 10-13 gram, Fructus Schisandrae Chinensis (processed with vinegar) 15-18 gram, Radix Bupleuri 20-24 gram and Folium Isatidis 30-45 gram.
The effect of Herba Artemisiae Scopariae wherein: be the dampness removing jaundice eliminating; skin ulcer is treated in detoxifcation; in we, adopt Herba Artemisiae Scopariae; because of Herba Artemisiae Scopariae has significant hepatic cholagogic effect; its mechanism of action is energy transaminase lowering activity; alleviate swelling of liver cell, the balloon sample becomes, and fat becomes and degree of necrosis; induce liver drug enzyme; strengthen the function of detoxification of liver, the complete sum of protection liver cell membrane promotes liver cell regeneration, to first, hepatitis B; icterohepatitis; significant curative effect is arranged, and Herba Artemisiae Scopariae has the promotion bile secretion, the effect that cholic acid and bilirubin are got rid of in the increase bile.Herba Artemisiae Scopariae has significant hepatoprotective effect, to first, and hepatitis B, icterohepatitis, significant curative effect is arranged. function of gallbladder promoting is arranged, promote bile secretion, the effect that cholic acid and bilirubin are discharged in the increase bile. can increase the heart coronary flow, microcirculation improvement, and blood pressure lowering is arranged, blood fat reducing, anticoagulation, diuresis is analgesic relievings asthma, and drives away ascarid and suppresses the effect of multiple pathogenic dermatophytes and antibacterial.
The effect of Herba Sedi: be the dampness removing jaundice eliminating, heat-clearing and toxic substances removing adopts Herba Sedi among the we, and light the oozing of Yin Qigan let out, the heat clearing away that is slightly cold can the dampness removing jaundice eliminating, and normal and Herba Artemisiae Scopariae are with usefulness, its pharmacological action has hepatoprotective effect, and acute to treating, chronic, active hepatitis all have the transaminase lowering effect.
The effect of Radix Et Rhizoma Rhei is: expelling pathogenic heat to loosen the bowels, removing pathogenic heat from blood and toxic substance from the body, effects such as removing blood stasis dysmenorrhea adopt Radix Et Rhizoma Rhei among the we, be to protect the liver because of it, choleretic effect, be obviously to reduce CCL4 etc. and cause the ALT value that liver is cured the wound, alleviate swelling of liver cell, degeneration and necrosis, its effect link comprises: promote the synthetic and liver cell regeneration of hepatocyte RNA, stimulate interferon to produce, suppress the breeding of virus, promote the liver blood circulation, microcirculation improvement etc., can dredge bile capillary in the liver, improve cholestasis in the biliary ductuli, promote gallbladder to shrink, lax gallbladder oddi sphincter promotes bile secretion and bilirubin to drain.
The effect of Carapax Trionycis (processed with vinegar): nourishing YIN for suppressing the hyperactive YANG, bring down a fever to remove and steam hard masses softening and resolving.It is that Carapax Trionycis (processed with vinegar) can improve the lymphoblastic transformation rate that we adopt it, prolongs the antibody time, raise immunity, and the protection adrenal cortex function can promote hemopoietic function, improves the white content of red eggs, can be used for the anemia due to the hepatopathy.Strong effect: the Trionyx sinensis Wiegmann polysaccharide can obviously improve mice hypoxia-bearing capability and anti-refrigeration, can prolong the mice swimming time, antifatigue effect is arranged, immunologic enhancement: the Trionyx sinensis Wiegmann polysaccharide can significantly improve mice plaque forming cells's haematolysis ability, promotes hemolytic antibody to generate; And strengthen mice delayed hypersensitivity, other: this product can suppress the hypertrophy of connective tissue, and caking can disappear; The effect that increases plasma protein is arranged, can be used for the anemia due to the hepatopathy.
The effect of Radix Salviae Miltiorrhizae is: timid stasis of blood pain relieving, the dysmenorrhea of invigorating blood circulation, relieving restlessness clears away heart-fire, it is the reparation and the regeneration that can promote multiple tissues such as liver, bone, skin because of its pharmacological action that we adopt Radix Salviae Miltiorrhizae, promote that wherein the reparation and the regeneration of hepatic tissue are especially remarkable, can suppress or alleviate hepatocellular degeneration, necrosis and inflammatory reaction reduce glutamate pyruvate transaminase in the serum, have certain promotion liver cell regeneration effect, the energy coronary artery dilator, increase coronary flow, improve myocardial ischemia, infraction and cardiac function, regulate the rhythm of the heart, and can expand peripheral blood vessel, microcirculation improvement; Can improve body's hypoxia tolerance; Anticoagulation is arranged, promote fibrinolytic, suppress platelet aggregation, suppress thrombotic effect; The energy blood fat reducing suppresses coronary atherosclerosis and forms; Can suppress or alleviate hepatocellular degeneration, necrosis and inflammatory reaction, promote liver cell regeneration, and anti-fibrosis effect is arranged; Can shorten the convalescent period of erythrocyte and hematochrome, Reticulocyte is increased, can promote the reparation of tissue, quicken the healing of fracture; There is nervus centralis that inhibitory action is arranged; Antitumor action is arranged; Energy enhancing human body immunity function; The energy blood sugar lowering; Various bacteria such as tubercule bacillus there is inhibitory action.
The effect of Huang Shi is: benefiting QI for strengthening the superficies, arresting sweating takes off admittedly, holder skin ulcer granulation promoting, inducing diuresis to remove edema.Adopt Huang Shi to increase because of the mechanism that protects the liver in the pharmacological action is to make hepatic glycogen among the we, the total serum protein and the albumin reduction that cause for liver injury have the rise effect, can increase
3The H-leucine mixes liver, and protein promotes its renewal, recovers the normal immunologic function of body, improves the ability of removing virus or suppressing the virus diffusion.
The effect of Rhizoma Smilacis Glabrae is: detoxicating and resolving stagnation of pathogens, and timid wind and removing obstruction in channels, dampness removing is let out turbid.It is in its pharmacological action that we adopt Rhizoma Smilacis Glabrae, and Rhizoma Smilacis Glabrae can discharge the inflammatory process of lymphokine and optionally suppress cell immune response by influencing the T lymphocyte, can strengthen we's detoxification and promoting urination effect with the Herba Artemisiae Scopariae compatibility.
The effect of the Radix Aucklandiae is promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.It is to be amusing because of this product gas perfume (or spice) that we adopt the Radix Aucklandiae, and acrid in the mouth can be manageed it, and bitterness the master let out, walk three warmers and gallbladder meridian, thus can the circulation of qi promoting spleen invigorating, again can depressed liver-energy dispersing and function of gallbladder promoting, can control the wet fortuneization of spleen, the liver failing to maintain the normal flow of QI and cause retention and fumigation of damp-heat inside the body, the abdominal distention of mechanism of qi retardance, hypochondriac pain, jaundice can with " Radix Et Rhizoma Rhei, Herba Artemisiae Scopariae " compatibility, make the irritability row, blood along and pain is ended, control the vexed belch of painful abdominal mass with this, edema abdominal distention, the dysentery beriberi, the merit of all transferring the diffusing gas that stagnates.But hot perfume belongs to sun, and sun then rises floating, stagnates as middle Jiao, following close-burning, row under palpus assistant Semen Arecae is fallen; Dry because of property perfume (or spice), same Rhizoma Coptidis, Radix Scutellariae are controlled dysentery, and same Cortex Phellodendri, Radix Stephaniae Tetrandrae are controlled beriberi, and all the cold medicine of mat and make it is dry is then used this god.If anger is gone against to attack and is dashed, all overly have a pain, with this lung qi is transferred, then lung qi if hepatic depression causes pain between side of body rib lower abdomen, is dredged it with Pericarpium Citri Reticulatae Viride from volt, makes the irritability row, and then blood ends along pain.
The effect of Herba Hedyotidis Diffusae is: heat-clearing and toxic substances removing, dampness removing is treating stranguria.Bold and unrestrained employing Herba Hedyotidis Diffusae is in its pharmacological action, and this product can stimulate the reticuloendothelial system hypertrophy in vivo, and enhancing antibody forms, and makes skein cell, leukocytic phagocytic activity strengthen, thereby reach antibiotic, antiphlogistic purpose.This product dampness removing of can heat clearing away holding concurrently again, modern clinical research this product can be used for multiple disease, jaundice due to damp-heat disease first-selection.
The effect of Fructus Schisandrae Chinensis (processed with vinegar) is: supplementing QI for promoting the production of body fluid, kidney calming restrains astringent or styptic treatment for spontaneous sweating.It is to be that because of the mechanism that protects the liver in its pharmacological action " the Fructus Schisandrae Chinensis sour in the mouth is sweet, and property theory thinks that acid can tonifying liver, slow liver that we adopt Fructus Schisandrae Chinensis.Studies show that; Fructus Schisandrae Chinensis and schizandrol thereof, schisandrin B have protective effect to acute and chronic liver injury; can alleviate hepatic necrosis; prevent that fatty from becoming, the antibody dimensionization, and serum ALT activities is significantly reduced; strengthen adrenal gland and matter function; the hepatocyte inflammatory reaction is alleviated, can supplementing QI for promoting the production of body fluid, the nourishing kidney of astringing the lung, antidiarrheal, arresting seminal emission, calm the nerves, can control diseases such as chronic cough dyspnea due to deficiency, the few xerostomia in Tianjin, seminal emission chronic diarrhea, forgetful insomnia.The pharmacological testing proof can be regulated central nervous system's excitement and process of inhibition, promotes body metabolism, regulates the secretion of gastric juice and bile, and hepatitis convalescent period transaminase rising person is had the reduction effect.
The effect of Radix Bupleuri is: evacuate and bring down a fever dispersing the stagnated live-QI to relieve the stagnation of QI, invigorating YANG QI to promote eruption.We's employing Radix Bupleuri is that the mechanism of hepatic cholagogic in its pharmacological action is that the hepatic injury that multiple reason causes is had certain preventive and therapeutic effect, ALT, AST are reduced, alleviate hepatocyte injury, promote that liver function recovery is normal, improve the resistivity of body to nonspecific stimulation, promote hepatocyte DNA synthetic, suppress the synthetic of extracellular matrix, can make bile output increase, reduce the cholic acid in the bile, bile pigments and content of cholesterol, Radix Bupleuri bitter in the mouth, suffering, cold nature; Return liver, gallbladder meridian; Little fragrant liter loose, and has clearing away heat and expelling pathogen in the exterior, treating SHAO YANG disease by mediation, dispersing the stagnated live-QI to relieve the stagnation of QI, the effect of ascending up spleen-Qi and Yang.
The curative effect of Folium Isatidis is: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.We adopt the Folium Isatidis pharmacological action that hepatitis B surface antigen is had inhibitory action.The modern clinical research Folium Isatidis is used for acute infectious hepatitis more, and record Folium Isatidis master pyrotoxic dysentery in the Compendium of Material Medica, jaundice, sore throat, erysipelas etc.
Four, specific implementation method
The medicine of first embodiment of the present invention is formed, and is made up of Herba Artemisiae Scopariae 60 grams, Herba Sedi 15 grams, Radix Et Rhizoma Rhei 10 grams, Carapax Trionycis (processed with vinegar) 5 grams, Radix Salviae Miltiorrhizae 10 grams, the Radix Astragali 10 grams, Rhizoma Smilacis Glabrae 3 grams, the Radix Aucklandiae 5 grams, Herba Hedyotidis Diffusae 10 grams, Fructus Schisandrae Chinensis (processed with vinegar) 15 grams, Radix Bupleuri 20 grams and Folium Isatidis 30 grams.
The fried one-tenth Chinese medicine of these several Chinese medicines soup, take for twice daily in morning and evening, seven days is a course of treatment, after the course of treatment, drug withdrawal 1-2 days, carries out next one course of treatment again.
The medicine of second embodiment of the present invention is formed, and is made up of Herba Artemisiae Scopariae 75 grams, Herba Sedi 30 grams, Radix Et Rhizoma Rhei 15 grams, Carapax Trionycis (processed with vinegar) 9 grams, Radix Salviae Miltiorrhizae 15 grams, the Radix Astragali 15 grams, Rhizoma Smilacis Glabrae 5 grams, the Radix Aucklandiae 7 grams, Herba Hedyotidis Diffusae 13 grams, Fructus Schisandrae Chinensis (processed with vinegar) 18 grams, Radix Bupleuri 24 grams and Folium Isatidis 45 grams.
The medicine of the 3rd embodiment of the present invention is formed, and is made up of Herba Artemisiae Scopariae 70 grams, Herba Sedi 22 grams, Radix Et Rhizoma Rhei 12 grams, Carapax Trionycis (processed with vinegar) 7 grams, Radix Salviae Miltiorrhizae 13 grams, the Radix Astragali 12 grams, Rhizoma Smilacis Glabrae 4 grams, the Radix Aucklandiae 6 grams, Herba Hedyotidis Diffusae 11.5 grams, Fructus Schisandrae Chinensis (processed with vinegar) 16.5 grams, Radix Bupleuri 22 grams and Folium Isatidis 37 grams.
In conjunction with concrete case the present invention is done to describe in detail.
The patient man, 12 years old, before not taking medicine of the present invention, glutamate pyruvate transaminase 395, glutamic oxaloacetic transaminase, GOT 397, albumin 27.5, globulin ratio 1.01, total bilirubin 341.5, bilirubin direct 195, TOTAL BILE ACID TBA 96.3, glutamyl-transpeptidase 91, alkali phosphatase 197, lactic acid dehydrogenase 288, take medicine of the present invention after four courses of treatment, glutamate pyruvate transaminase 23, glutamic oxaloacetic transaminase, GOT 36, albumin 40, globulin ratio 36.1, total bilirubin 20.7, bilirubin direct 18.9, TOTAL BILE ACID TBA 10.8, glutamyl transpeptidase 59, alkali phosphatase 139, lactic acid dehydrogenase 254, hepatitis b surface antigen positive 1:32.
The patient man, 30 years old, before not taking medicine of the present invention, glutamate pyruvate transaminase 455, glutamic oxaloacetic transaminase, GOT 497, albumin 32.5, globulin ratio 1.08, total bilirubin 441.5, bilirubin direct 225.9, TOTAL BILE ACID TBA 106.3, glutamyl-transpeptidase 91, alkali phosphatase 197, lactic acid dehydrogenase 268, take medicine of the present invention after four courses of treatment, glutamate pyruvate transaminase 13, glutamic oxaloacetic transaminase, GOT 39, albumin 42, globulin ratio 36.1, total bilirubin 23.7, bilirubin direct 12.9, TOTAL BILE ACID TBA 10.8, glutamyl transpeptidase 58, alkali phosphatase 139, lactic acid dehydrogenase 154, hepatitis b surface antigen positive 1:32.
The patient man, 50 years old, before not taking medicine of the present invention, glutamate pyruvate transaminase 355, glutamic oxaloacetic transaminase, GOT 399, albumin 25.5, globulin ratio 1.08, total bilirubin 391.5, bilirubin direct 205.9, TOTAL BILE ACID TBA 106.3, glutamyl-transpeptidase 91, alkali phosphatase 197, lactic acid dehydrogenase 289, take medicine of the present invention after four courses of treatment, glutamate pyruvate transaminase 28, glutamic oxaloacetic transaminase, GOT 38, albumin 36, globulin ratio 35.1, total bilirubin 23.7, bilirubin direct 19.9, TOTAL BILE ACID TBA 11.8, glutamyl transpeptidase 58, alkali phosphatase 129, lactic acid dehydrogenase 184, hepatitis b surface antigen positive 1:30.
The patient man, 60 years old, before not taking medicine of the present invention, glutamate pyruvate transaminase 457, glutamic oxaloacetic transaminase, GOT 490, albumin 22.5, globulin ratio 0.98, total bilirubin 397.5, bilirubin direct 225.9, TOTAL BILE ACID TBA 106.3, glutamyl-transpeptidase 91, alkali phosphatase 197, lactic acid dehydrogenase 290, take medicine of the present invention after four courses of treatment, glutamate pyruvate transaminase 25, glutamic oxaloacetic transaminase, GOT 39, albumin 35, globulin ratio 35.1, total bilirubin 23.7, bilirubin direct 14.9, TOTAL BILE ACID TBA 10.8, glutamyl transpeptidase 56, alkali phosphatase 135, lactic acid dehydrogenase 154, hepatitis b surface antigen positive 1:29.
Patient woman, 20 years old, before not taking medicine of the present invention, glutamate pyruvate transaminase 555, glutamic oxaloacetic transaminase, GOT 500, albumin 21.5, globulin ratio 1.02, total bilirubin 401.5, bilirubin direct 225.9, TOTAL BILE ACID TBA 103.3, glutamyl transpeptidase 87, alkali phosphatase 197, lactic acid dehydrogenase 290, take medicine of the present invention after four courses of treatment, glutamate pyruvate transaminase 18, glutamic oxaloacetic transaminase, GOT 39, albumin 35, globulin ratio 35.7, total bilirubin 25.7, bilirubin direct 14.9, TOTAL BILE ACID TBA 11.8, glutamyl transpeptidase 59, alkali phosphatase 138, lactic acid dehydrogenase 158, hepatitis b surface antigen positive 1:30.
Patient woman, 48 years old, before not taking medicine of the present invention, glutamate pyruvate transaminase 458, glutamic oxaloacetic transaminase, GOT 498, albumin 30.5, globulin ratio 1.06, total bilirubin 396.5, bilirubin direct 225.9, TOTAL BILE ACID TBA 104.3, glutamyl transpeptidase 89, alkali phosphatase 189, lactic acid dehydrogenase 286, take medicine of the present invention after four courses of treatment, glutamate pyruvate transaminase 17, glutamic oxaloacetic transaminase, GOT 37, albumin 37, globulin ratio 35.1, total bilirubin 22.7, bilirubin direct 15.9, TOTAL BILE ACID TBA 11.8, glutamyl transpeptidase 61, alkali phosphatase 135, lactic acid dehydrogenase 164, hepatitis b surface antigen positive 1:31.
Therefore the present invention in conjunction with traditional Chinese medical science traditional theory and modern treatment theory, treats the better effects if of icterohepatitis according to traditional Chinese medical science traditional theory and modern treatment theory.
In the technical field of the Chinese medicine composition that is used for the treatment of icterohepatitis, every technology contents of being made up of Herba Artemisiae Scopariae 60-75 gram, Herba Sedi 15-30 gram, Radix Et Rhizoma Rhei 10-15 gram, Carapax Trionycis (processed with vinegar) 5-9 gram, Radix Salviae Miltiorrhizae 10-15 gram, Radix Astragali 10-15 gram, Rhizoma Smilacis Glabrae 3-5 gram, Radix Aucklandiae 5-7 gram, Herba Hedyotidis Diffusae 10-13 gram, Fructus Schisandrae Chinensis (processed with vinegar) 15-18 gram, Radix Bupleuri 20-24 gram and Folium Isatidis 30-45 gram of including is all in protection scope of the present invention.
Claims (1)
1. Chinese medicine composition that is used for the treatment of icterohepatitis, it is characterized in that medicine forms, form by Herba Artemisiae Scopariae 60-75 gram, Herba Sedi 15-30 gram, Radix Et Rhizoma Rhei 10-15 gram, Carapax Trionycis (processed with vinegar) 5-9 gram, Radix Salviae Miltiorrhizae 10-15 gram, Radix Astragali 10-15 gram, Rhizoma Smilacis Glabrae 3-5 gram, Radix Aucklandiae 5-7 gram, Herba Hedyotidis Diffusae 10-13 gram, Fructus Schisandrae Chinensis (processed with vinegar) 15-18 gram, Radix Bupleuri 20-24 gram and Folium Isatidis 30-45 gram.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102626509A (en) * | 2012-04-21 | 2012-08-08 | 张金梅 | Traditional Chinese medicine composite for curing pediatric jaundice |
CN103550740A (en) * | 2013-11-01 | 2014-02-05 | 杨献华 | Traditional Chinese medicinal composition for treating icterohepatitis and application of traditional Chinese medicinal composition |
CN105250959A (en) * | 2015-10-27 | 2016-01-20 | 哈尔滨市康隆药业有限责任公司 | Traditional Chinese medicine preparation for repairing liver damage and preparation method |
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CN1076626A (en) * | 1993-01-19 | 1993-09-29 | 李先文 | Medicine taken after being mixed with boiling water for liver trouble |
CN1994378A (en) * | 2006-12-27 | 2007-07-11 | 常熟雷允上制药有限公司 | Compound formulation for treating icteric viral hepatitis and method for preparing same |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102626509A (en) * | 2012-04-21 | 2012-08-08 | 张金梅 | Traditional Chinese medicine composite for curing pediatric jaundice |
CN102626509B (en) * | 2012-04-21 | 2013-11-06 | 张金梅 | Traditional Chinese medicine composite for curing pediatric jaundice |
CN103550740A (en) * | 2013-11-01 | 2014-02-05 | 杨献华 | Traditional Chinese medicinal composition for treating icterohepatitis and application of traditional Chinese medicinal composition |
CN103550740B (en) * | 2013-11-01 | 2015-06-10 | 杨献华 | Traditional Chinese medicinal composition for treating icterohepatitis and application of traditional Chinese medicinal composition |
CN105250959A (en) * | 2015-10-27 | 2016-01-20 | 哈尔滨市康隆药业有限责任公司 | Traditional Chinese medicine preparation for repairing liver damage and preparation method |
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