CN102219752A - 一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的新晶型d - Google Patents
一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的新晶型d Download PDFInfo
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- CN102219752A CN102219752A CN 201110100792 CN201110100792A CN102219752A CN 102219752 A CN102219752 A CN 102219752A CN 201110100792 CN201110100792 CN 201110100792 CN 201110100792 A CN201110100792 A CN 201110100792A CN 102219752 A CN102219752 A CN 102219752A
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- triazole
- difluorobenzyl
- methane amide
- trifluoroacetic acid
- crystal formation
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Priority Applications (1)
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CN 201110100792 CN102219752B (zh) | 2011-04-21 | 2011-04-21 | 一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的晶型d |
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CN 201110100792 CN102219752B (zh) | 2011-04-21 | 2011-04-21 | 一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的晶型d |
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Publication Number | Publication Date |
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CN102219752A true CN102219752A (zh) | 2011-10-19 |
CN102219752B CN102219752B (zh) | 2013-04-10 |
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CN 201110100792 Expired - Fee Related CN102219752B (zh) | 2011-04-21 | 2011-04-21 | 一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的晶型d |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4789680A (en) * | 1982-12-23 | 1988-12-06 | Ciba-Geigy Corporation | Aralkyltriazole compounds |
CN1225087A (zh) * | 1996-07-11 | 1999-08-04 | 诺瓦提斯公司 | 1-取代的4-氰基-1,2,3-三唑的制备方法 |
WO2010043849A1 (en) * | 2008-10-13 | 2010-04-22 | Cipla Limited | Process for the preparation of rufinamide |
CN101768124A (zh) * | 2008-12-30 | 2010-07-07 | 北京本草天源药物研究院 | 一种药物晶体及其制备方法和用途 |
US20100234616A1 (en) * | 2009-03-16 | 2010-09-16 | Dipharma Francis S.R.L. | Method for the preparation of rufinamide |
US20110034523A1 (en) * | 2009-08-04 | 2011-02-10 | Dipharma Francis S.R.L. | Crystalline forms of rufinamide |
-
2011
- 2011-04-21 CN CN 201110100792 patent/CN102219752B/zh not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4789680A (en) * | 1982-12-23 | 1988-12-06 | Ciba-Geigy Corporation | Aralkyltriazole compounds |
CN1225087A (zh) * | 1996-07-11 | 1999-08-04 | 诺瓦提斯公司 | 1-取代的4-氰基-1,2,3-三唑的制备方法 |
WO2010043849A1 (en) * | 2008-10-13 | 2010-04-22 | Cipla Limited | Process for the preparation of rufinamide |
CN101768124A (zh) * | 2008-12-30 | 2010-07-07 | 北京本草天源药物研究院 | 一种药物晶体及其制备方法和用途 |
US20100234616A1 (en) * | 2009-03-16 | 2010-09-16 | Dipharma Francis S.R.L. | Method for the preparation of rufinamide |
US20110034523A1 (en) * | 2009-08-04 | 2011-02-10 | Dipharma Francis S.R.L. | Crystalline forms of rufinamide |
Non-Patent Citations (3)
Title |
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《Progress in Natural Science》 20060930 WANG Junmin et al. Synthesis and anticonvulsant activity of 1-substituted benzyl-N-substituted-1,2,3-triazole-4-formamides 925-929 1-3、9、10 第16卷, 第9期 * |
《Tetrahedron Letters》 20100418 Whitney H. Mudd, Erland P. Stevens An efficient synthesis of rufinamide, an antiepileptic drug 3229-3231 1-3、10 第51卷, * |
《中国医药工业杂志》 20101231 居文建等 卢非酰胺的合成 247-248 1-3、10 第41卷, 第4期 * |
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Publication number | Publication date |
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CN102219752B (zh) | 2013-04-10 |
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Address after: 100021 Beijing city Chaoyang District West business center boziwan Jinhai rich 402 (A) 21 storey building Applicant after: China Resources Saike Pharmaceutical Co., Ltd. Address before: 100021 Beijing city Chaoyang District West business center boziwan Jinhai rich 402 (A) 21 storey building Applicant before: Saike Pharmaceutical Co., Ltd., Beijing |
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Free format text: CORRECT: APPLICANT; FROM: SAIKE PHARMACEUTICAL CO., LTD., BEIJING TO: CHINA RESOURCES SAIKE PHARMACEUTICAL CO., LTD. |
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Effective date of registration: 20160115 Address after: 100028 Beijing City, Chaoyang District Shuguang Sirirath A Phoenix Plaza No. 5 block 27 layer Patentee after: Beijing General Pharmaceutical Corporation Address before: 100021 Beijing city Chaoyang District West business center boziwan Jinhai rich 402 (A) 21 storey building Patentee before: China Resources Saike Pharmaceutical Co., Ltd. |
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Granted publication date: 20130410 Termination date: 20210421 |