A kind of Chinese medicine composition for the treatment of silt sample cholelithiasis
Technical field
The present invention relates to a kind of Chinese prescription, especially a kind of Chinese medicine composition for the treatment of silt sample cholelithiasis.
Background technology
Cholelithiasis belongs to the sick category of traditional Chinese medical science hypochondriac pain, mainly is damp and hot decocting, and forms sandstone, blocks due to the biliary tract.Calculus the greater can be taked operative treatment, but the muddy stone operative treatment is difficult to remove, and easily recurrence, causes very big misery to the patient.
Summary of the invention
Main task of the present invention is to provide a kind of Chinese medicine composition for the treatment of silt sample cholelithiasis at above problem, and this medicine has clearing away heat-damp and promoting diuresis, effect that calculus is treating stranguria
The present invention selects Endothelium Corneum Gigeriae Galli, Herba Lysimachiae, Spora Lygodii, Radix Clematidis, Herba Artemisiae Scopariae, Semen Trichosanthis, Radix Glycyrrhizae, yellow wine, crystal sugar to make up, and makes each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat silt sample cholelithiasis.
Endothelium Corneum Gigeriae Galli wherein: the gizzard inwall of Phasianidae animal man chicken (Gallus gallus domesticus Brisson).Nature and flavor are sweet, and are cold.Return spleen, stomach, small intestinal, urinary bladder channel.Effect with promoting digestion and invigorating the stomach.
Herba Lysimachiae: be Primulaceae plant Lysimachia christinae Hance (formal name used at school: dry herb Lysimachia christinae Hance).Sweet, the little hardship of nature and flavor, cold.Return liver, gallbladder, kidney, urinary bladder channel.Has relieving stranguria by diuresis; Heat-clearing and toxic substances removing; The effect of dissipating blood stasis for subsidence of swelling cures mainly liver and gall and urinary system calculus.
Above-mentioned Endothelium Corneum Gigeriae Galli heavily fortified point helps digestion and activating the spleen; Herba Lysimachiae relieving stranguria by diuresis and calculus. the two 5 usefulness has the effect of dissovling and discharging calculus, activating the spleen diuretic.
Spora Lygodii: be the spore of Lygodiaceae plant Spora Lygodii Lygodium japonicum (Thunb.) Sw..Cold in nature, sweet in the mouth.Return bladder, small intestine meridian.Effect with eliminating damp-heat, treating stranguria pain relieving, diuresis and expelling stone.Experiment shows that after the Spora Lygodii preparation was injected to anesthetized dog, its ureteral peristalsis frequency obviously increased, and ureter epimere cavity pressure obviously raises. the prompting Spora Lygodii has the effect of the calculus of promotion.
Radix Clematidis: be the dry root and rhizome of dicotyledon Ranunculaceae Ranunculaceae Radix Clematidis Clematis chinensis Osbeck, Clematis hexapetala (mountain knotweed) C.hexapetala Pall. or northeast clematis (black common vetch) C.manshurica Rupr..The nature and flavor suffering is salty, and temperature is poisonous.Go into urinary bladder channel.Has promoting urination to remove dampness, removing obstruction in the collateral to relieve pain, expectorant water, the effect of the hypochondriac lump of loosing.
Herba Artemisiae Scopariae: be the seedling of feverfew Herba Artemisiae Scopariae Artemisia capillaris Thunb..Nature and flavor are slightly cold, and are hot, bitter.Return spleen, stomach, liver, gallbladder meridian.Have hepatic cholagogic, clearing away heat-damp and promoting diuresis, promote bile secretion, the effect that cholic acid and bilirubin are discharged in the increase bile
Semen Trichosanthis: sweet in flavor and cold in property for the seed of cucurbitaceous plant Fructus Trichosanthis and Chinese Fructus Trichosanthis, go into lung, stomach, large intestine channel.Effect with Qinghua heat-phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, loosening bowel to relieve constipation.
Radix Glycyrrhizae: be dicotyledon pulse family Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. G.inflata Bat., or the root and rhizome of Glycyrrhiza glabra L. G.glabra L..Property is put down, and sweet in the mouth is returned 12 warps.Has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.
Yellow wine and crystal sugar: the effective ingredient of medicine can not only be dissolved out, be easy to absorption of human body, can also arrive the position that needs treatment so as to the guiding drug effect.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have curative effect preferably in the following weight parts scope: Endothelium Corneum Gigeriae Galli 4-8 part, Herba Lysimachiae 1-5 part, Spora Lygodii 1-5 part, Radix Clematidis 1-5 part, Herba Artemisiae Scopariae 1-3 part, Semen Trichosanthis 1-3 part, Radix Glycyrrhizae 0.5-2 part, crystal sugar 0.5-2 part, yellow wine are an amount of.
Wherein be preferably: 6 parts of Endothelium Corneum Gigeriae Galli, 3 parts of Herba Lysimachiaes, 3 parts of Spora Lygodii, 3 parts of Radix Clematidis, 2 parts of Herba Artemisiae Scopariaes, 2 parts of Semen Trichosanthiss, 1 part in Radix Glycyrrhizae, 1 part in crystal sugar, yellow wine are an amount of.
The present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, oral liquid etc.For example these crude drug decoctings can be got filtrate after filtration, add antiseptic and make oral liquid; Also can directly take decoction in case of necessity.
The present invention has clearing away heat-damp and promoting diuresis, effect that calculus is treating stranguria, can effectively promote smooth muscle of bile vesica to shrink, and makes the Oddi sphincter dilatation, impels cholelithiasis to discharge, and we also have simultaneously and eliminate the cholecystitis card that cholelithiasis caused, and promote the recovery of cholecystitis.According to clinical 120 routine patients are observed statistics, take medicine total effective rate course of treatment total effective rate 95.8%, two course of treatment 99.2% of the present invention.
The specific embodiment
Embodiment one, 4 parts of Endothelium Corneum Gigeriae Galli, 1 part of Herba Lysimachiae, 1 part of Spora Lygodii, 1 part of Radix Clematidis, 1 part of Herba Artemisiae Scopariae, 1 part of Semen Trichosanthis, 0.5 part in Radix Glycyrrhizae, 0.5 part in crystal sugar, yellow wine are an amount of.
Embodiment two: 6 parts of Endothelium Corneum Gigeriae Galli, 3 parts of Herba Lysimachiaes, 3 parts of Spora Lygodii, 3 parts of Radix Clematidis, 2 parts of Herba Artemisiae Scopariaes, 2 parts of Semen Trichosanthiss, 1 part in Radix Glycyrrhizae, 1 part in crystal sugar, yellow wine are an amount of.
Embodiment three: 8 parts of Endothelium Corneum Gigeriae Galli, 5 parts of Herba Lysimachiaes, 5 parts of Spora Lygodii, 5 parts of Radix Clematidis, 3 parts of Herba Artemisiae Scopariaes, 3 parts of Semen Trichosanthiss, 2 parts in Radix Glycyrrhizae, 2 parts in crystal sugar, yellow wine are an amount of.
Its manufacture method is: with the weighting raw materials (daily dose) proportionally of Endothelium Corneum Gigeriae Galli, Herba Lysimachiae, Spora Lygodii, Radix Clematidis, Herba Artemisiae Scopariae, Semen Trichosanthis, Radix Glycyrrhizae in the foregoing description, get an amount of yellow wine and soaked said medicine 2-3 hour, the yellow wine consumption was not advisable just to have said medicine, conventional manufacture method according to Chinese medicine decoction decocts then, get Tonga and go into the guiding drug crystal sugar and divide two parts, sooner or later each portion.
Be the clinical statistics data that the patient uses medicine of the present invention below:
One, physical data
Accept outpatient service and inpatient totally 120 examples for medical treatment, symptoms such as pain are arranged repeatedly under the right rib of outbreak, make a definite diagnosis through ultrasound diagnosis, man's 62 examples, woman's 58 examples, age 31-56 year, 39.6 years old mean age, the course of disease 6 months is with interior person's 58 examples, 6 months-1 year person's 32 examples, person's 30 examples more than 1 year, wherein, be full of type muddy stone 45 examples in the gallbladder, non-type muddy stone 75 examples that are full of in the gallbladder.
Two, tcm diagnosis standard
Persistence distending pain under the right rib, and take on the back radiation to the right, companion's nausea and vomiting, inappetence, slight fever, red tongue, yellow, thin and slightly greasy fur, wiry and frequent pulse.
Three, Therapeutic Method
Make the decoction of a daily dose according to above-mentioned manufacture method, divide two parts, sooner or later each portion.3 days is a course of treatment.
Four, efficacy assessment standard
1, cure: sings and symptoms disappears.Imaging examination (B ultrasonic, PTC, ERCP, biliary tract vein or peroral contrast must have wherein 2 kinds of inspection methods) calculus disappears.
2, produce effects: sings and symptoms obviously alleviates, and imaging examination calculus obviously minimizing reaches more than 1/2, or calculus diminishes 1/2 above person.
3, effective: sings and symptoms has and alleviates.The imaging examination calculus reduces or the person of diminishing before the treatment.
4, invalid: sings and symptoms has and alleviates or no change.The imaging examination calculus does not have the changer.
Five, therapeutic outcome statistics
Wherein: total effective rate=cure rate+obvious effective rate+effective percentage.