CN102188487A - Traditional Chinese preparation for treating rhinitis and preparation method thereof - Google Patents
Traditional Chinese preparation for treating rhinitis and preparation method thereof Download PDFInfo
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- CN102188487A CN102188487A CN 201110119471 CN201110119471A CN102188487A CN 102188487 A CN102188487 A CN 102188487A CN 201110119471 CN201110119471 CN 201110119471 CN 201110119471 A CN201110119471 A CN 201110119471A CN 102188487 A CN102188487 A CN 102188487A
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Abstract
The invention relates to a traditional Chinese preparation for treating rhinitis and a preparation method thereof. The traditional Chinese preparation for treating rhinitis is prepared from the following raw materials and auxiliary materials in parts by weight: 1-8 parts of magnolia biondii pamp volatile oil or magnolia biondii pamp volatile oil mixture, 1-6 parts of borneolum syntheticum, 1-3 parts of peppermint oil, 10-40 parts of absolute ethyl alcohol, 20-80 parts of tween-80 and 5-40 parts of purified water, thus being made into spraying agent. The invention has the advantages that: compared with the prior art, the formula constitution is clear, the preparation has obvious curative effects on treating acute and chronic and allergic rhinitis. In addition, the preparation method is simple and convenient for process, and thus the quality is easy to control. The preparation does not contain ephedrine or nemazoline, thus overcoming the side effect of causing medicamentous rhinitis and the like easily caused by long-time administration of other medicaments. People are administrated by directly spraying the nasal cavity, the advantages of uniform local administration, fast adsorption and action, and obvious curative effect can be achieved. The traditional Chinese preparation is effective on the rhinitis and has no toxic and side effects.
Description
Technical field:
The present invention relates to a kind of Chinese medicine preparation that is used for the treatment of rhinitis and preparation method thereof, belong to technical field of Chinese medicines.
Technical background:
Rhinitis is a commonly encountered diseases, frequently-occurring disease.Rhinitis is the inflammation of nasal membrane and submucous tissue.Show as hyperemia or edema, the patient nasal obstruction occurs through regular meeting, stream clear water tears, rhinocnesmus, throat's discomfort, symptoms such as cough.The number of suffering from rhinitis at present is more and more, and the age trend becomes younger.Pathogenic factors has 1, inherited genetic factors, 2. nasal mucosa susceptibility, 3. antigenic substance.The type of rhinitis has a variety of: 1, acute rhinitis: due to the actute infection, be commonly called as " cold " or " flu ", General Symptoms can be arranged; Friendship with autumn and winter or winter-spring season is seen more.2, chronic rhinitis: be common frequently-occurring disease, develop by acute rhinitis.Thoroughly and repeatedly do not show effect relevant with the secondary infection of merging antibacterial, treatment.Be nasal membrane and submucosal chronic inflammatory disease.Very common, the lighter is called simple property chronic rhinitis, and weight person is called hypertrophic rhinitis.3, allergic rhinitis: be nasal membrane to suck airborne some composition extremely sensitive due to.Its symptom is very similar to flu, but can repeatedly show effect in one day; When not showing effect, then normal fully.The disease appearing at regular intervals and the season of allergic rhinitis are closely related.4, medicamentous rhinitis: medicamentous rhinitis is the result of the long-term continuous action of inappropriate nasal cavity applied medicine, and also can be regarded as is a kind of chronic rhinitis.Its pathogenesis is exactly inappropriate nasal cavity applied medicine, comprises that the intensive nasal mucosa vessels of use effect shrinks nasal drop, liquor strength medicinal liquid, over administration or the long-term prescription etc. of oozing such as too high, non-.These all can damage the structure of nasal mucosa cilium, thereby influence the physiological function of nasal mucosa, produce clinical disease.5, allergic rhinitis: be commonly called as allergic rhinitis, its cardinal symptom is unexpected rhinocnesmus, sneeze, snivel, nasal obstruction, and outbreak repeatedly.All violate the patient throughout the year and be the perennial allergic rhinitis, only in fixed season, send out the author and be seasonal allergic rhinitis.The former is mainly by dust, acarid, mycete and cotton-wool etc. cause that the latter is mainly caused by pollen within doors.This disease belongs to I metallergy disease.6, seasonal rhinitis: be called " pollinosis " again, its morbidity has obvious seasonal, and spring and autumn is season occurred frequently.
Summary of the invention:
The objective of the invention is to: provide to disclose a kind of Chinese medicine preparation that is used for the treatment of rhinitis, another object of the present invention also is the preparation method of the above-mentioned Chinese medicine preparation of open preparation.
Chinese medicine preparation of the present invention is that former, the adjuvant with following weight ratio is that component is made: 1～8 part in Flos Magnoliae volatile oil or Flos Magnoliae volatile oil mixture, 1～6 part of Borneolum Syntheticum, 1～3 part of Oleum menthae, 10～40 parts of dehydrated alcohol, 20～50 parts of tween 80s, 5～40 parts of purified water.
The preparation method of preparation of the present invention: get Flos Magnoliae by required weight portion and be ground into coarse powder, steam distillation or supercritical CO
2The fluid extraction method is extracted Flos Magnoliae volatile oil or mixture of volatile oil, and is standby; Get Borneolum Syntheticum adding dehydrated alcohol and make dissolving, add purified water, Flos Magnoliae volatile oil or mixture of volatile oil and Oleum menthae, tween 80 mix homogeneously again, make spray.
Flos Magnoliae is one of principal agent of the treatment cacorhinia recorded of Chinese Pharmacopoeia, suffering, temperature.Has dispersing wind and cold, the effect of clearing the nasal passage.Volatile oil is the Flos Magnoliae effective ingredient, has effects such as analgesia, calmness, antiallergic, and can shrink nasal mucosa vessels, eliminates swelling, and certain antibacterial and anti-inflammation functions is arranged.Key medicine for diseases such as treatment headache, nasal sinusitis, nasal obstruction are obstructed.Be usually used in treating all kinds rhinitis clinically.
Borneolum Syntheticum, hot, bitter, be slightly cold.Has the refreshment of having one's ideas straightened out, the effect of clearing away heat to alleviate pain.Has antibacterial and antiphlogistic pharmacological action.Be usually used in treatment of allergic rhinitis clinically.
Herba Menthae, hot, cool.Has dispelling wind-heat, refresh oneself, the effect of rash.Oleum menthae is the effective ingredient of Herba Menthae, can promote secretion showing as aspect the effect of respiratory system, makes the dilution of heavy-gravity mucus, and shows tangible mitigation.
In sum, the Chinese medicine preparation that is used for the treatment of rhinitis of the present invention has the effect of treatment acute and chronic and allergic rhinitis.
The Chinese medicine preparation that is used for the treatment of rhinitis of the present invention be on clinical experience basis for many years, sum up be used for the treatment rhinitis the efficacious prescriptions medicine arranged.
Beneficial effect of the present invention: compared with prior art, prescription of the present invention constitutes, and therapeutic effect clear and definite, preparation is obvious, has the effect of treatment acute and chronic and allergic rhinitis.Easy, the control of being convenient to quality of preparation method technology simultaneously.This preparation does not contain ephedrine or azoles quinoline how, has overcome the other drug life-time service and has easily caused side effect such as medicamentous rhinitis.Adopt the direct spray delivery of nasal cavity, have topical evenly, absorb fast rapid-action characteristics evident in efficacy.Rhinitis is had therapeutical effect and has no side effect.
The specific embodiment:
Embodiment 1: get Flos Magnoliae 200g and be ground into coarse powder, steam distillation extracts volatile oil, and is standby.Get Borneolum Syntheticum 3.3g adding 40ml dehydrated alcohol and make dissolving, add the 30ml purified water again, mix homogeneously.Flos Magnoliae volatile oil and Oleum menthae 2.0ml and 3ml tween 80 mix homogeneously with above-mentioned solution mix homogeneously, are made spray.
Embodiment 2: get Flos Magnoliae 100g and be ground into coarse powder, steam distillation extracts volatile oil, and is standby.Get Borneolum Syntheticum 3.3g adding 40ml dehydrated alcohol and make dissolving, add the 30ml purified water again, mix homogeneously.Flos Magnoliae volatile oil and Oleum menthae 3.0ml and 3ml tween 80 mix homogeneously with above-mentioned solution mix homogeneously, are made spray.
Embodiment 3: get Flos Magnoliae 300g and be ground into coarse powder, steam distillation extracts volatile oil, and is standby.Get Borneolum Syntheticum 1.7g adding 25ml dehydrated alcohol and make dissolving, add the 45ml purified water again, mix homogeneously.Flos Magnoliae volatile oil and Oleum menthae 1.0ml and 3ml tween 80 mix homogeneously with above-mentioned solution mix homogeneously, are made spray.
Embodiment 4: get Flos Magnoliae 200g and be ground into coarse powder, put supercritical CO
2In the fluid extraction device, extract the Flos Magnoliae volatile oil mixture, standby.Get Borneolum Syntheticum 3.3g adding 40ml dehydrated alcohol and make dissolving, add the 30ml purified water again, mix homogeneously.Flos Magnoliae volatile oil mixture and Oleum menthae 2.0ml and 3ml tween 80 mix homogeneously with above-mentioned solution mix homogeneously, are made spray.
Embodiment 5: get Flos Magnoliae 100g and be ground into coarse powder, put supercritical CO
2In the fluid extraction device, extract the Flos Magnoliae volatile oil mixture, standby.Get Borneolum Syntheticum 3.3g adding 40ml dehydrated alcohol and make dissolving, add the 30ml purified water again, mix homogeneously.Flos Magnoliae volatile oil mixture and Oleum menthae 3.0ml and 3ml tween 80 mix homogeneously with above-mentioned solution mix homogeneously, are made spray.
Embodiment 6: get Flos Magnoliae 300g and be ground into coarse powder, put supercritical CO
2In the fluid extraction device, extract the Flos Magnoliae volatile oil mixture, standby.Get Borneolum Syntheticum 1.7g adding 25ml dehydrated alcohol and make dissolving, add the 45ml purified water again, mix homogeneously.Flos Magnoliae volatile oil mixture and Oleum menthae 1.0ml and 3ml tween 80 mix homogeneously with above-mentioned solution mix homogeneously, are made spray.
Claims (2)
1. Chinese medicine preparation that is used for the treatment of rhinitis is characterized in that: described Chinese medicine preparation is that former, the adjuvant with following weight ratio is that component is made: 1～8 part in Flos Magnoliae volatile oil or Flos Magnoliae volatile oil mixture, 1～6 part of Borneolum Syntheticum, 1～3 part of Oleum menthae, 10～40 parts of dehydrated alcohol, 20～50 parts of tween 80s, 5～40 parts of purified water.
2. a preparation method that is used for the treatment of the Chinese medicine preparation of rhinitis according to claim 1 is characterized in that: get Flos Magnoliae by required weight portion and be ground into coarse powder, steam distillation or supercritical CO
2The fluid extraction method is extracted Flos Magnoliae volatile oil or mixture of volatile oil, and is standby; Get Borneolum Syntheticum adding dehydrated alcohol and make dissolving, add purified water, Flos Magnoliae volatile oil or mixture of volatile oil and Oleum menthae, tween 80 mix homogeneously again, make spray.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201110119471 CN102188487A (en) | 2011-05-04 | 2011-05-04 | Traditional Chinese preparation for treating rhinitis and preparation method thereof |
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| CN 201110119471 CN102188487A (en) | 2011-05-04 | 2011-05-04 | Traditional Chinese preparation for treating rhinitis and preparation method thereof |
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| CN102188487A true CN102188487A (en) | 2011-09-21 |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406745A (en) * | 2011-12-06 | 2012-04-11 | 广东药学院 | Traditional Chinese medicine composition for treating rhinitis and preparation method thereof |
| CN103054944A (en) * | 2013-02-05 | 2013-04-24 | 吴正虎 | Patchouli oil-peppermint oil soft capsule and preparation method |
| CN106822243A (en) * | 2017-03-02 | 2017-06-13 | 河南利欣制药股份有限公司 | It is a kind of to treat compound preparation of anemofrigid cold and preparation method thereof |
| CN108904644A (en) * | 2018-10-08 | 2018-11-30 | 广东云瑶生物医药科技有限公司 | Borneol larynx nose is logical and preparation method thereof |
| CN110215481A (en) * | 2019-06-13 | 2019-09-10 | 贵州良济药业有限公司 | A kind of Chinese medicine composition that treating allergic rhinitis and preparation method |
| CN110604759A (en) * | 2018-06-15 | 2019-12-24 | 哈尔滨吉利达科技有限公司 | Rhinitis spray and preparation method thereof |
| CN111346126A (en) * | 2018-12-24 | 2020-06-30 | 韩长序 | Medicinal liquor for treating rhinitis |
| CN111803538A (en) * | 2020-08-16 | 2020-10-23 | 张称浩 | Atomizing irrigation traditional Chinese medicine for rhinitis and application thereof |
| CN113730458A (en) * | 2021-06-18 | 2021-12-03 | 蔡爱军 | Nasal cavity dripping (spraying) liquid for eliminating snore |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1589876A (en) * | 2004-03-31 | 2005-03-09 | 通化斯威药业股份有限公司 | Medicine for treating Aids |
-
2011
- 2011-05-04 CN CN 201110119471 patent/CN102188487A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1589876A (en) * | 2004-03-31 | 2005-03-09 | 通化斯威药业股份有限公司 | Medicine for treating Aids |
Non-Patent Citations (1)
| Title |
|---|
| 《质谱学报》 20071231 赵欧; 梁逸曾 《辛夷挥发油不同提取方法的研究》 106 2 , * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406745A (en) * | 2011-12-06 | 2012-04-11 | 广东药学院 | Traditional Chinese medicine composition for treating rhinitis and preparation method thereof |
| CN103054944A (en) * | 2013-02-05 | 2013-04-24 | 吴正虎 | Patchouli oil-peppermint oil soft capsule and preparation method |
| CN106822243A (en) * | 2017-03-02 | 2017-06-13 | 河南利欣制药股份有限公司 | It is a kind of to treat compound preparation of anemofrigid cold and preparation method thereof |
| CN110604759A (en) * | 2018-06-15 | 2019-12-24 | 哈尔滨吉利达科技有限公司 | Rhinitis spray and preparation method thereof |
| CN108904644A (en) * | 2018-10-08 | 2018-11-30 | 广东云瑶生物医药科技有限公司 | Borneol larynx nose is logical and preparation method thereof |
| CN111346126A (en) * | 2018-12-24 | 2020-06-30 | 韩长序 | Medicinal liquor for treating rhinitis |
| CN110215481A (en) * | 2019-06-13 | 2019-09-10 | 贵州良济药业有限公司 | A kind of Chinese medicine composition that treating allergic rhinitis and preparation method |
| CN111803538A (en) * | 2020-08-16 | 2020-10-23 | 张称浩 | Atomizing irrigation traditional Chinese medicine for rhinitis and application thereof |
| CN113730458A (en) * | 2021-06-18 | 2021-12-03 | 蔡爱军 | Nasal cavity dripping (spraying) liquid for eliminating snore |
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Application publication date: 20110921 |