CN102143766B - 包括可生物降解性聚合物的掺混物的医疗器械和方法 - Google Patents

包括可生物降解性聚合物的掺混物的医疗器械和方法 Download PDF

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Publication number
CN102143766B
CN102143766B CN200980135834.0A CN200980135834A CN102143766B CN 102143766 B CN102143766 B CN 102143766B CN 200980135834 A CN200980135834 A CN 200980135834A CN 102143766 B CN102143766 B CN 102143766B
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China
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phase
axis
polymer
strain
polymer blend
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Chinese (zh)
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CN102143766A (zh
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J·张
S·刘
J·L·施莱
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Medtronic Inc
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Medtronic Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/041Mixtures of macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Prostheses (AREA)
CN200980135834.0A 2008-08-06 2009-08-04 包括可生物降解性聚合物的掺混物的医疗器械和方法 Active CN102143766B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8670708P 2008-08-06 2008-08-06
US61/086,707 2008-08-06
US12/534,264 2009-08-03
US12/534,264 US8129477B1 (en) 2008-08-06 2009-08-03 Medical devices and methods including blends of biodegradable polymers
PCT/US2009/052626 WO2010017153A2 (en) 2008-08-06 2009-08-04 Medical devices and methods including blends of biodegradable polymers

Publications (2)

Publication Number Publication Date
CN102143766A CN102143766A (zh) 2011-08-03
CN102143766B true CN102143766B (zh) 2014-04-23

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Country Status (6)

Country Link
US (1) US8129477B1 (enExample)
EP (1) EP2318059B1 (enExample)
JP (1) JP2011530331A (enExample)
CN (1) CN102143766B (enExample)
ES (1) ES2704014T3 (enExample)
WO (1) WO2010017153A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8496865B2 (en) * 2010-10-15 2013-07-30 Abbott Cardiovascular Systems Inc. Method to minimize chain scission and monomer generation in processing of poly(L-lactide) stent
US10940167B2 (en) 2012-02-10 2021-03-09 Cvdevices, Llc Methods and uses of biological tissues for various stent and other medical applications
WO2014124356A2 (en) 2013-02-11 2014-08-14 Cook Medical Technologies Llc Expandable support frame and medical device
WO2015034889A2 (en) 2013-09-04 2015-03-12 Zzyzx Polymers LLC Methods for increasing throughput rates of solid-state extrusion devices
WO2015054595A1 (en) * 2013-10-12 2015-04-16 Zzyzx Polymers LLC Fabricating drug delivery systems
US20230323115A1 (en) * 2020-10-30 2023-10-12 Toray Industries, Inc. Polymer composition and molded article

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1468273A (zh) * 2000-08-23 2004-01-14 E�����ݻ���ҵ���޹�˾ 适用作层制品覆盖层和包裹物及其它包装材料的可生物降解聚合物膜和片
CN101205356A (zh) * 2006-12-22 2008-06-25 深圳市奥贝尔科技有限公司 聚羟基烷酸酯及其共聚物与聚乳酸的共混改性

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4844854A (en) 1987-09-22 1989-07-04 United States Surgical Corporation Process for making a surgical device using two-phase compositions
US5252642A (en) 1989-03-01 1993-10-12 Biopak Technology, Ltd. Degradable impact modified polyactic acid
US5641501A (en) 1994-10-11 1997-06-24 Ethicon, Inc. Absorbable polymer blends
US5871468A (en) 1996-04-24 1999-02-16 Medtronic, Inc. Medical catheter with a high pressure/low compliant balloon
US5756651A (en) * 1996-07-17 1998-05-26 Chronopol, Inc. Impact modified polylactide
US6150493A (en) 1997-06-12 2000-11-21 General Electric Company Process for the preparation of poly(ester-carbonate)s
DE19755966B4 (de) * 1997-12-16 2004-08-05 Urs J. Dr. Hänggi Verwendung von Formulierungen von wasserfesten, biologisch abbaubaren Polymeren aus nachwachsenden Rohstoffen mit erhöhter Bindungsaffinität zur Herstellung von Trägern für Analysensysteme und Testsysteme aus diesen Formulierungen
GB9814609D0 (en) 1998-07-07 1998-09-02 Smith & Nephew Polymers
US6400992B1 (en) 1999-03-18 2002-06-04 Medtronic, Inc. Co-extruded, multi-lumen medical lead
US6607548B2 (en) 2001-05-17 2003-08-19 Inion Ltd. Resorbable polymer compositions
US6926903B2 (en) 2001-12-04 2005-08-09 Inion Ltd. Resorbable polymer composition, implant and method of making implant
US20030105530A1 (en) 2001-12-04 2003-06-05 Inion Ltd. Biodegradable implant and method for manufacturing one
GB0202233D0 (en) 2002-01-31 2002-03-20 Smith & Nephew Bioresorbable polymers
GB0317192D0 (en) 2003-07-19 2003-08-27 Smith & Nephew High strength bioresorbable co-polymers
US20050137360A1 (en) 2003-12-19 2005-06-23 General Electric Company Clear polycarbonate polyester blend
US8747878B2 (en) 2006-04-28 2014-06-10 Advanced Cardiovascular Systems, Inc. Method of fabricating an implantable medical device by controlling crystalline structure
US20060041102A1 (en) 2004-08-23 2006-02-23 Advanced Cardiovascular Systems, Inc. Implantable devices comprising biologically absorbable polymers having constant rate of degradation and methods for fabricating the same
CA2619571A1 (en) 2005-08-18 2007-02-22 Smith & Nephew, Plc High strength devices and composites
US20090274742A1 (en) 2005-08-18 2009-11-05 Brown Malcolm Nmi Multimodal high strength devices and composites
WO2007066345A1 (en) 2005-12-09 2007-06-14 Council Of Scientific & Industrial Research A melt transurethane process for the preparation of polyurethanes
WO2007092417A1 (en) * 2006-02-07 2007-08-16 Tepha, Inc. Toughened polylactic acid polymers and copolymers
US20070203569A1 (en) * 2006-02-24 2007-08-30 Robert Burgermeister Implantable device formed from polymer blends having modified molecular structures
GB0605885D0 (en) 2006-03-24 2006-05-03 Smith & Nephew Composite Material
US7964210B2 (en) 2006-03-31 2011-06-21 Abbott Cardiovascular Systems Inc. Degradable polymeric implantable medical devices with a continuous phase and discrete phase
CA2652753C (en) 2006-05-12 2015-12-08 Cordis Corporation Balloon expandable bioabsorbable drug eluting stent
US20080033540A1 (en) 2006-08-01 2008-02-07 Yunbing Wang Methods to prepare polymer blend implantable medical devices
US7923022B2 (en) 2006-09-13 2011-04-12 Advanced Cardiovascular Systems, Inc. Degradable polymeric implantable medical devices with continuous phase and discrete phase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1468273A (zh) * 2000-08-23 2004-01-14 E�����ݻ���ҵ���޹�˾ 适用作层制品覆盖层和包裹物及其它包装材料的可生物降解聚合物膜和片
CN101205356A (zh) * 2006-12-22 2008-06-25 深圳市奥贝尔科技有限公司 聚羟基烷酸酯及其共聚物与聚乳酸的共混改性

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
聚合物增强增韧机理研究进展;杨伏生等;《中国塑料》;20010831;第15卷(第8期);全文 *

Also Published As

Publication number Publication date
CN102143766A (zh) 2011-08-03
ES2704014T3 (es) 2019-03-13
EP2318059A2 (en) 2011-05-11
WO2010017153A2 (en) 2010-02-11
US8129477B1 (en) 2012-03-06
JP2011530331A (ja) 2011-12-22
EP2318059B1 (en) 2018-10-03
WO2010017153A3 (en) 2011-03-31

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