CN102133360B - Oral administration medicament for treating dysphagia and preparation method thereof - Google Patents
Oral administration medicament for treating dysphagia and preparation method thereof Download PDFInfo
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- CN102133360B CN102133360B CN201110044832.XA CN201110044832A CN102133360B CN 102133360 B CN102133360 B CN 102133360B CN 201110044832 A CN201110044832 A CN 201110044832A CN 102133360 B CN102133360 B CN 102133360B
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Abstract
The invention discloses an oral administration medicament for treating dysphagia and a preparation method thereof. The oral administration medicament consists of the following Chinese medicinal raw materials: notoginseng root, dragon's blood, barbed skullcap herb, spreading hedyotis herb, agaric, raw hawthorn fruit, chicken's gizzard-membrane, chinaroot greenbrier, Chinese fan palm, Chinese date and liquoric root. The preparation method comprises the following steps of: crushing notoginseng root and dragon's blood, sieving with a 300-mesh sieve, and bottling for later use; putting the other nine medicaments into a marmite, adding water until the water is above 2 centimeters of the medicaments, decocting over strong fire, decocting over slow fire for 30 minutes, pouring liquid medicine, and decocting once again by the same method; mixing the liquid medicine decocted at two times and concentrating until paste is formed, and pouring medicinal powder formed by crushing notoginseng root and dragon's blood into the marmite quickly, stirring and mixing fully and uniformly; pouring medicinal paste out, putting into a drying oven, drying at the temperature of between 45 and 55 DEG C, crushing and sieving with a 300-mesh sieve; and loading medicinal powder into capsules, wherein 0.3 gram of medicinal powder is loaded in each capsule. The oral administration medicament for treating dysphagia has an obvious effect, effective rate of 96 percent and cure rate of 80 percent.
Description
Technical field
The invention belongs to pure technical field of Chinese medicines, specifically a kind of dysphagic endo-medicine and preparation method thereof for the treatment of.
Background technology
A dysphagic disease is the name of disease of the traditional Chinese medical science, is similar to esophageal carcinoma, gastric cancer, the pyloric obstruction of modern medicine, is a kind of digestive tract disease.Choke, refer to swallow under food difficulty, diaphragm, refers to that chest and diaphragm blocks, and eats food and does not swallow, or swallow and spue, and is referred to as dysphagic.Chinese medicine thinks have because of expectorant stasis of blood person, has because of blood stasis person, has because of gastric qi upper punch person, has because the dried-up person of cardia causes and under food difficulty, forms dysphagic person.Western medicine expectant treatment and operative treatment for doctor trained in Western medicine, cause life danger and very large burden economically to people.In medical medical science innermost thoughts and feelings < < to open the loose > > therapeutic effect of diaphragm also not obvious.
Summary of the invention
Object of the present invention is just to provide a kind for the treatment of to choke and uses rear instant effect, and effect is remarkable, cheapness, and pure Chinese medicine is easily got in medicine source.
Technical scheme of the present invention is to realize like this, a kind ofly treat dysphagic endo-medicine, it is characterized in that: it is to be made by the raw material of Chinese medicine of following weight parts Radix Notoginseng 30, Sanguis Draxonis 25, Herba Scutellariae Barbatae 18, Herba Hedyotidis Diffusae 18, Polyporus 50, Fructus Crataegi 100, Endothelium Corneum Gigeriae Galli 20, Rhizoma Smilacis Chinensis 18, seed of Livistona chinensis R.Br. 18, Fructus Jujubae 60, Radix Glycyrrhizae 15.
The preparation method of medicine of the present invention is as follows: first Radix Notoginseng 30, Sanguis Draxonis 25 were pulverized to 300 mesh sieves altogether, receive bottle standby, then by Herba Scutellariae Barbatae 18, Herba Hedyotidis Diffusae 18, Polyporus 50, Fructus Crataegi 100, Endothelium Corneum Gigeriae Galli 20, Rhizoma Smilacis Chinensis 18, seed of Livistona chinensis R.Br. 18, Fructus Jujubae 60, Radix Glycyrrhizae 15.Above 9 taste medicines are placed in marmite, then to pouring in marmite, crossing 2 centimetres of medicines soaks 20 minutes, water is poured out, to pouring in marmite, cross 2 centimetres of medicines again, endure out with high heat, then with slow fire, endure 30 minutes, then water is poured out, in marmite, pouring is crossed 2 centimetres of medicines again, endure out with high heat, then with slow fire, endure 30 minutes, then water is poured out, again the liquid medicine of enduring for twice is poured on together and is concentrated, when liquid medicine is concentrated into cream rapidly by Radix Notoginseng 30, the medicated powder that Sanguis Draxonis 25 was pulverized 300 mesh sieves is altogether poured in marmite and is stirred and makes it abundant mix homogeneously, then ointment is poured out and is placed on (temperature is controlled at 45-55 ℃) oven dry in drying baker, pulverized again 300 mesh sieves, medicated powder is encapsulated, every capsules fills 0.3 gram.
Medicine of the present invention also can be processed into tablet, powder, honeyed pill, the watered pill by above method.
Medicine of the present invention has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, eliminating carbuncle pain relieving, hard masses softening and resolving, promoting digestion and removing stagnation, the function of eliminating dampness and diuresis.
Medicine of the present invention is suitable for dysphagic disease, comprises esophageal carcinoma, gastric cancer, pyloric obstruction.
Main disease is seen: food difficulty is swallowed, distension and fullness in the abdomen, and the indistinct pain of stomach, dyspepsia, Ai gas, or spue after food, thirst with desire to drink, yellow urine, the pallor of breathing hard, puffiness of the face and dropsy of the feet, becomes thin.
Instructions of taking: day takes 3 times, each serving 3, taking medicine before meal.
Treat the course for the treatment of: within 90 days, be a course for the treatment of, the lighter, can cure 1-2 the course for the treatment of, severe one, can cure 2-3 the course for the treatment of.
Apply Drug therapy cardiac spasm disease of the present invention, successful, has no side effect, effective percentage 96%, cure rate 80%.
Drug action mechanism of the present invention is as follows:
Herba Scutellariae Barbatae: bitter in the mouth, cold nature.There is heat-clearing and toxic substances removing, the merit of inducing diuresis to remove edema.This product, for conventional anticarcinogen, can be used for the treatment of kinds cancer, see (813 pages of < < TCM Recipe pharmacy > >, the Guangdong college of traditional Chinese medicine compiles, and the Guangdong People's Press publishes.
Rhizoma Smilacis Chinensis: sweet in the mouth, light, cold nature.There is heat-clearing and toxic substances removing, the merit of wind-damp dispelling.This product is used for esophageal carcinoma, as esophageal carcinoma, gastric cancer, colon cancer etc., (the same, to see 812 pages)
Seed of Livistona chinensis R.Br.: sweet in the mouth, puckery, property is flat.The merit with hard masses softening and resolving.Can be used for the treatment of kinds cancer, (the same, to see 820 pages)
Herba Hedyotidis Diffusae: sweet in the mouth, light,, cold nature.There is heat-clearing and toxic substances removing, the merit of eliminating damp-heat.(the same, to see 179 pages)
Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature.Enter liver, stomach warp.There is hemostasis by removing blood stasis, the merit of reducing swelling and alleviating pain (the same, to see 527 pages)
Sanguis Draxonis: sweet in the mouth, salty.Property is put down.Enter the heart, Liver Channel.There is astringing to arrest bleeding, stasis-dispelling and pain-killing, the merit of sore life.(the same, to see 530-531 page)
Polyporus: sweet in the mouth, light, property is flat.Enter kidney, urinary bladder channel.The merit with promoting diuresis to eliminate damp pathogen.(the same, to see 305 pages)
Fructus Crataegi: sour in the mouth, sweet, warm in nature.Enter spleen, stomach, Liver Channel.There is dyspepsia and intestinal stasis relieving, the merit of blood stasis-eliminating and stagnation-dissipating.(the same, to see 461 pages)
Endothelium Corneum Gigeriae Galli: sweet in the mouth, puckery, property is flat.Enter spleen, stomach, small intestinal, urinary bladder channel.There is promoting digestion and removing stagnation, arresting enursis, the merit that fossil is treating stranguria.(the same, to see 463-464 page)
Fructus Jujubae: sweet in the mouth, property are put down.Matter is moistened many liquid, enters spleen, stomach warp.There is spleen reinforcing stomach reinforcing, the merit of the mediation property of medicine.(the same, to see 601-602 page)
Radix Glycyrrhizae: sweet in the mouth, property are put down.Enter spleen, lung meridian.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, nourishing the lung to arrest cough, the mediation property of medicine, the function of relieving spasm to stop pain.(the same, to see 602-603 page)
Chinese medicine thinks, cardiac spasm disease cause mostly is feelings will and does not relax, due to functional activity of QI being not smooth.Functional activity of QI being not smooth makes depression of liver-QI, and the organic complication of internal organs often appears in incoordination between the liver and stomach.The traditional Chinese medical science is said, " sad spleen, excessive anger impairing the liver ".Damage of the spleen is depressed, and depressed body fluid is cloth not, and body fluid not cloth is gathered into expectorant; Liver hinders the stagnation of QI, and the stagnation of QI blood operation is not smooth, and blood operation is not smooth, becomes the stasis of blood, and the expectorant stasis of blood is handed over and to be hindered in esophagus, food be difficult for into; Friendship hinders in stomach easily tells, abdominal distention, biochemical resource is few at least in feed, for a long time poly-stomach internal organs must fire-transformation occur scorching hot, constipation due to dry stool, even angiorrhexis is bled.Disease sees that eating difficulty swallows, distension and fullness in the abdomen, and Ai gas, or spue after food, thirst with desire to drink, yellow urine, the pallor of breathing hard, puffiness of the face and dropsy of the feet, becomes thin.Control suitable heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, eliminating carbuncle pain relieving, promoting digestion and removing stagnation, eliminating dampness and diuresis is controlled getting twice the result with half the effort of cardiac spasm disease to reach.
The present invention selects Radix Notoginseng, Sanguis Draxonis blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain; Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Rhizoma Smilacis Chinensis, seed of Livistona chinensis R.Br. heat-clearing and toxic substances removing, hard masses softening and resolving; Fructus Crataegi, Endothelium Corneum Gigeriae Galli promoting digestion and removing stagnation; Polyporus promoting diuresis to eliminate damp pathogen; Fructus Jujubae, Radix Glycyrrhizaeization Yin and promoting production of body liquid, coordinating the actions of various ingredients in a prescription, all medicines are synthetic has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, eliminating carbuncle pain relieving, promoting digestion and removing stagnation, the merit of eliminating dampness and diuresis, can cure rapidly cardiac spasm disease.
Specific embodiments
Below in conjunction with embodiment, the invention will be further described:
Embodiment: get Radix Notoginseng 30, Sanguis Draxonis 25, Herba Scutellariae Barbatae 18,, Herba Hedyotidis Diffusae 18, Polyporus 50, Fructus Crataegi 100, Endothelium Corneum Gigeriae Galli 20, Rhizoma Smilacis Chinensis 18, seed of Livistona chinensis R.Br. 18, Fructus Jujubae 60, Radix Glycyrrhizae 15.
The method for the treatment of of medicine of the present invention is as follows: first Radix Notoginseng 30, Sanguis Draxonis 25 were pulverized to 300 mesh sieves altogether, and received bottle standby, then by Herba Scutellariae Barbatae 18, Herba Hedyotidis Diffusae 18, Polyporus 50, Fructus Crataegi 100, Endothelium Corneum Gigeriae Galli 20, Rhizoma Smilacis Chinensis 18, seed of Livistona chinensis R.Br. 18, Fructus Jujubae 60, Radix Glycyrrhizae 15.Above 9 taste medicines are placed in marmite, then to pouring in marmite, cross 2 centimetres of medicines and soak 20 minutes, water is poured out, then cross 2 centimetres of medicines to pouring in marmite, endure out with high heat, then with slow fire, endure 30 minutes, then liquid medicine is poured out; To pouring in marmite, cross 2 centimetres of medicines again, endure out with high heat, then with slow fire, endure 30 minutes, then liquid medicine is poured out; Again the liquid medicine of enduring for twice is poured on together and is concentrated, the medicated powder of rapidly Radix Notoginseng 30, Sanguis Draxonis 25 being pulverized altogether to 300 mesh sieves when liquid medicine is concentrated into cream is poured in marmite and is stirred and makes it abundant mix homogeneously, then ointment is poured out and is placed on (temperature is controlled at 45-55 ℃) oven dry in drying baker, pulverized again 300 mesh sieves, medicated powder is encapsulated, and every capsules fills 0.3 gram.
Medicine of the present invention also can be processed into tablet, powder, honeyed pill, the watered pill by above method.
Medicine of the present invention has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, eliminating carbuncle pain relieving, hard masses softening and resolving, promoting digestion and removing stagnation, the function of eliminating dampness and diuresis.
Medicine of the present invention is suitable for dysphagic disease, comprises esophageal carcinoma, gastric cancer, pyloric obstruction.
Main disease is seen: food difficulty is swallowed, distension and fullness in the abdomen, and the indistinct pain of stomach, dyspepsia, Ai gas, or spue after food, thirst with desire to drink, yellow urine, the pallor of breathing hard, puffiness of the face and dropsy of the feet, becomes thin.
Instructions of taking: day takes 3 times, each serving 3, taking medicine before meal.
Treat the course for the treatment of: within 90 days, be a course for the treatment of, the lighter, can cure 1-2 the course for the treatment of, severe one, can cure 2-3 the course for the treatment of.
Apply secret prescription handed down in the family from generation to generation treatment cardiac spasm disease of the present invention, successful, has no side effect, effective percentage 96%, cure rate 80%.
For showing the curative effect of medicine of the present invention, 200 routine patients for the treatment of are divided into matched group and experimental group, vertical shelves stay looks in addition Statistical Comparison.Matched group 100 examples, 40 routine esophageal carcinoma wherein, 50 routine gastric cancer, pyloric obstruction 10 examples, with < <, open the loose > > of diaphragm and treat 1-3 the course for the treatment of, take 1 dose every day, after supper, take half an hour; Experimental group 100 examples, 40 routine esophageal carcinoma wherein, 50 routine gastric cancer, pyloric obstruction 10 examples, with Drug therapy 1-3 of the present invention course for the treatment of, per diem take 3 times, each serving 3, taking medicine before meal; All with symptom food difficulty, swallow, distension and fullness in the abdomen, the indistinct pain of stomach, dyspepsia, Ai gas, or spue after food, thirst with desire to drink, yellow urine, the pallor of breathing hard, puffiness of the face and dropsy of the feet, becomes thin and alleviates as effectively; Symptom food difficulty is swallowed, distension and fullness in the abdomen, and Ai gas, or spue after food, thirst with desire to drink, yellow urine, the pallor of breathing hard, puffiness of the face and dropsy of the feet, becomes thin and disappears for recovery from illness, and statistics shows that result is as follows:
Table 1: matched group curative effect situation
Table 2, experimental group curative effect situation
For showing that curative effect illustrates:
Example 1, Wu X, 61 years old now, people from West Lake, Yanggu County, went to a doctor over 2006, ill before 5 years, was diagnosed as pyloric obstruction through Liaocheng City the People's Hospital, and disease is seen: Ai gas, singultus, spues after food, and one's belly is tight as a drum, greasy fur, thready pulse.Clinical diagnosis is pyloric obstruction, gets medicine of the present invention and per diem takes 3 times, and each serving 3, taking medicine before meal, takes 90 days, and symptom all disappears, and follows up a case by regular visits to so far not recurrence.
Example 2, poplar X, man, 69 years old now, Yanggu County Shouzhang people from town, 2007 go to a doctor, before 3 years, suffer from gastropathy, epigastric distending pain, dyspepsia, after feed, pain increases the weight of, vomiting band blood, through the ultrasound diagnosis of Liaocheng City the People's Hospital, is diagnosed as gastric ulcer, gastric cancer, disease is seen: Ai gas, and stomach tenderness pain, becomes thin, the pallor of breathing hard, greasy fur, thready pulse.Tell to withdraw all medicines, take medicine of the present invention, per diem take 3 times, each serving 3, taking medicine before meal, takes 180 days, and symptom all disappears, and follows up a case by regular visits to so far not recurrence.
Claims (1)
1. treat dysphagic endo-medicine for one kind, it is characterized in that: it is comprised of the raw material of Chinese medicine of following weight parts, Radix Notoginseng 30, Sanguis Draxonis 25, Herba Scutellariae Barbatae 18, Herba Hedyotidis Diffusae 18, Polyporus 50, Fructus Crataegi 100, Endothelium Corneum Gigeriae Galli 20, Rhizoma Smilacis Chinensis 18, seed of Livistona chinensis R.Br. 18, Fructus Jujubae 60, Radix Glycyrrhizae 15; First Radix Notoginseng 30, Sanguis Draxonis 25 were pulverized to 300 mesh sieves altogether, receive bottle standby, then by Herba Scutellariae Barbatae 18, Herba Hedyotidis Diffusae 18, Polyporus 50, Fructus Crataegi 100, Endothelium Corneum Gigeriae Galli 20, Rhizoma Smilacis Chinensis 18, seed of Livistona chinensis R.Br. 18, Fructus Jujubae 60, Radix Glycyrrhizae 15, above 9 taste medicines are placed in marmite, then to pouring in marmite, cross 2 centimetres of medicines and soak 20 minutes, water is poured out, to pouring in marmite, cross 2 centimetres of medicines again, endure out with high heat, then with slow fire, endure 30 minutes, then liquid medicine is poured out; To pouring in marmite, cross 2 centimetres of medicines again, endure out with high heat, then with slow fire, endure 30 minutes, then liquid medicine is poured out, then the liquid medicine of enduring for twice is poured on together and is concentrated, the medicated powder of rapidly Radix Notoginseng 30, Sanguis Draxonis 25 being pulverized altogether to 300 mesh sieves when liquid medicine is concentrated into cream is poured in marmite and is stirred and makes it abundant mix homogeneously, then ointment is poured out to be placed in drying baker and dry, temperature is controlled at 45-55 ℃, then pulverizes 300 mesh sieves, medicated powder is encapsulated, and every capsules fills 0.3 gram.
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104523927A (en) * | 2014-12-09 | 2015-04-22 | 蒋勇 | Traditional Chinese medicine composition for treating phlegm stagnant type esophageal cancer and application thereof |
| CN105582369A (en) * | 2015-09-18 | 2016-05-18 | 王浩敏 | Traditional Chinese medicine for treating diffuse esophagisms |
| CN106177756A (en) * | 2016-07-26 | 2016-12-07 | 冷国玉 | A kind of treat dysphagic Chinese medicine composition |
| CN107412652A (en) * | 2017-09-04 | 2017-12-01 | 王文春 | A kind of medicine for treating dysphagia and regurgitation and preparation method thereof |
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| CN1973886A (en) * | 2006-11-01 | 2007-06-06 | 薛志清 | Gastropathy treating Chinese medicine composition and its prepn form and prepn process |
| CN101391019A (en) * | 2008-10-23 | 2009-03-25 | 蒋月芳 | Internal medicine for treating breast carcinoma |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1973886A (en) * | 2006-11-01 | 2007-06-06 | 薛志清 | Gastropathy treating Chinese medicine composition and its prepn form and prepn process |
| CN101391019A (en) * | 2008-10-23 | 2009-03-25 | 蒋月芳 | Internal medicine for treating breast carcinoma |
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| 全蝎治疗恶性肿瘤的临床研究;刘玉清等;《热带医学杂志》;20031231;第3卷(第04期);484-488 * |
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