CN102133314A - 治疗溃疡性结肠炎的中药制剂 - Google Patents
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Abstract
本发明属于中药制剂领域，特别涉及一种治疗溃疡性结肠炎的中药制剂，其特征在于是由如下重量份数的原料制成：白芍3份、枳实2份、槟榔1份、防风1份、丹参2份、焦楂3份、茯苓3份、白头翁3份和败酱草3份。本发明是在传统的中医辩证施治的基础上结合临床实践研制而成的，诸药相合具有行气活血佐以理脾的功效，治疗溃疡性结肠炎具有疗效显著、见效快、安全方便、无毒副作用、不易复发等优点。
Description
技术领域
本发明属于中药制剂领域，特别涉及一种治疗溃疡性结肠炎的中药制剂。
背景技术
溃疡性结肠炎是一种原因不明的直肠和结肠非特异性的炎性疾患，病变部位一般在直肠和乙状结肠，发病年龄以20-40岁多见，常见的临床症状为长期不明原因的腹痛、腹泻，里急后重，粘液和脓血便，且有反复发作、不易治愈的特点。该病属中医的腹痛、肠癖范围，多因湿热、气滞血瘀、寒热错杂日久伤及脾肾所致，其病机是脾胃受伤、运化失调、气滞血瘀，中医通过辩证施治取得了很好的治疗效果。
发明内容
本发明所要解决的技术问题是提供一种具有行气活血佐以理脾之功的治疗溃疡性结肠炎的中药制剂，克服了现有治疗溃疡性结肠炎技术疗程长、效果慢、副作用大等缺点。
本发明治疗溃疡性结肠炎的中药制剂，其特征在于是由如下重量份数的原料制成：白芍3份、枳实2份、槟榔1份、防风1份、丹参2份、焦楂3份、茯苓3份、白头翁3份和败酱草3份。
制备方法：按重量份数称取上述原料，洗净、去杂、晾干；粉碎成颗粒，置多功能提取罐中加水煎煮二次，第一次加总药材10倍量的水煎煮2小时，取煎液，第二次加总药材7倍量的水煎煮1小时；取两次煎液混合、过滤，热封袋中，每袋200ml，100℃高温灭菌，包装即得。口服，一次一袋，日服二次，十天为一个疗程。
本发明药物机理如下：
白芍：养血调经、平肝止痛、敛阴止汗，本品养肝阴、调肝气、平肝阳、缓急止痛。
枳实：破气除痞、化痰消积，本品能行气化痰以消痞、破气除满而止痛。
槟榔：驱虫消积、行气利水，本品善行胃肠之气，消积导滞。
防风：发表散风、胜湿止痛、止痉、止泻，本品临床中常用于肝郁侮脾、腹痛泄泻及肠风下血。
丹参：活血调经、凉血消痛、安神，本品取其活血化瘀之功涤荡胃肠之瘀毒。
焦楂：消食化积、行气散瘀，取本品行气止痛之力缓其肠中积气、活血化瘀祛其瘀毒。
茯苓：利水渗湿、健脾安神，本品特点补而不峻、利而不猛，既能祛邪又能扶正、补脾。
白头翁：清热解毒、凉血止痛，本品尤善清肠胃湿热及血分热毒。
败酱草：清热解毒、消痈排脓、祛瘀止痛，本品辛散苦泄，既能解毒排脓又能活血消痈，故常用于治疗肠道瘀毒。
本发明药物有如下优点：
(1)本发明所使用的中草药符合《中华人民共和国药典》规定，药物安全可靠。
(2)本发明不仅可治疗溃疡性结肠炎，对溃疡性结肠炎的预防也有很好的作用。诸药相合共具有行气活血佐以理脾之功，治疗溃疡性结肠炎具有疗效显著、见效快、安全方便、无毒副作用、不易复发等优点。
疗效判断：
痊愈：反复发作性腹痛、腹泻、脓血便等症状完全消失；查体，全腹无压痛、腹软无包块；X线检查，结肠无异常发现。
好转：反复发作性腹痛、腹泻等症状明显好转，腹泻次数减少、无脓血便及粘液便；触诊，腹软无包块，右下腹有时有压痛感、无反跳痛。
无效：症状无改善，同治疗前。
治疗结果：治疗溃疡性结肠炎患者120例，患者服用本发明汤剂，每日早晚各一次，每次一袋，十天为一个疗程。经过四个疗程治疗，痊愈80例，占67％，好转24例，占20％，无效16例，占13％，总有效率87％。通过四个疗程治疗观察，病人无任何不良反应，三大常规化验及肝肾功能检测未发现异常现象。
以下列举几个典型病例：
病例1：患者任某某，男，40岁，患溃疡性结肠炎一年余，中西医治疗病情时轻时重，本次因受凉后致病情加重，明显的腹痛、腹泻、里急后重、脓血便(日便5-6次)，于2004年6月15日来诊我院，口服本发明药物治疗一疗程后症状明显改善，治疗四个疗程后症状完全消失，全身无阳性体征可查，X线检查正常。随访一年无复发。
病例2：患者窦某某，女，45岁，患溃疡性结肠炎2年余，病情时轻时重，本次因生气致宿疾复发，明显的腹痛、里急后重、脓血便，口服本发明药物治疗四个疗程后症状完全消失，各项检查正常，随访一年无复发。
病例3：患者张某某，女，50岁，患溃疡性结肠炎半年余，本次因过度劳累后致病情加重，腹痛、腹泻、粘液便(日便3-5次)，伴有恶心、呕吐、食欲欠佳，乏力，脘腹胀满；于2000年11月10日来诊我院，查，全腹压痛左下腹明显，有时可触及肿块；口服本发明药物治疗四个疗程后症状完全消失，全身无阳性体征可查，随访一年无复发。
具体实施方式
实施例：汤剂，按重量份数称取原料：白芍3份、枳实2份、槟榔1份、防风1份、丹参2份、焦楂3份、茯苓3份、白头翁3份和败酱草3份。制备方法：洗净、去杂、晾干；粉碎成颗粒，置多功能提取罐中加水煎煮二次，第一次加总药材10倍量的水煎煮2小时，取煎液，第二次加总药材7倍量的水煎煮1小时；取两次煎液混合、过滤，热封袋中，每袋200ml，100℃高温灭菌，包装即得。
Claims (1)
1.一种治疗溃疡性结肠炎的中药制剂，其特征在于是由如下重量份数的原料制成：白芍份、枳实 份、槟榔 份、防风 份、丹参 份、焦楂 份、茯苓 份、白头翁 份和败酱草 份。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893457A (zh) * | 2014-03-31 | 2014-07-02 | 王红 | 一种治疗溃疡性结肠炎中药 |
| CN104958462A (zh) * | 2015-07-25 | 2015-10-07 | 王璐 | 一种治疗十二指肠溃疡的中药 |
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| CN101703750A (zh) * | 2009-11-13 | 2010-05-12 | 王心聚 | 一种治疗胃肠病的中药制剂 |
| CN101732666A (zh) * | 2009-11-04 | 2010-06-16 | 泰一和浦（北京）中医药研究院有限公司 | 一种治疗肝炎晚期病证的中药组合物及其制备方法 |
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| CN101732666A (zh) * | 2009-11-04 | 2010-06-16 | 泰一和浦（北京）中医药研究院有限公司 | 一种治疗肝炎晚期病证的中药组合物及其制备方法 |
| CN101703750A (zh) * | 2009-11-13 | 2010-05-12 | 王心聚 | 一种治疗胃肠病的中药制剂 |
Non-Patent Citations (2)
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| 《内蒙古中医药》 20050131 鲁文明 中医药治疗功能性消化不良研究进展 , 第1期 2 * |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893457A (zh) * | 2014-03-31 | 2014-07-02 | 王红 | 一种治疗溃疡性结肠炎中药 |
| CN103893457B (zh) * | 2014-03-31 | 2018-04-17 | 王红 | 一种治疗溃疡性结肠炎中药 |
| CN104958462A (zh) * | 2015-07-25 | 2015-10-07 | 王璐 | 一种治疗十二指肠溃疡的中药 |
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